Journal of Yeungnam Medical Science

Volume 38(1); January 2021

Review articles

Gastroenterology and Hepatology
Gallbladder polyps: evolving approach to the diagnosis and management: Kook Hyun Kim; Yeungnam Univ J Med. 2021;38(1):1-9. Published online May 15, 2020; DOI: https://doi.org/10.12701/yujm.2020.00213

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Gallbladder (GB) polyp is a mucosal projection into the GB lumen. With increasing health awareness, GB polyps are frequently found using ultrasonography during health screening. The prevalence of GB polyps ranges between 1.3% and 9.5%. Most patients are asymptomatic and have benign characteristics. Of the nonneoplastic polyps, cholesterol polyps are most common, accounting for 60%–70% of lesions. However, a few polyps have malignant potential. Currently, the guidelines recommend laparoscopic cholecystectomy for polyps larger than 1 cm in diameter due to their malignan potential. The treatment algorithm can be influenced by the size, shape, and numbers of polyps, old age (>50 years), the presence of primary sclerosing cholangitis, and gallstones. This review summarizes the commonly recognized concepts on GB polyps from diagnosis to an algorithm of treatment.

Citations

Citations to this article as recorded by

Predicting Neoplastic Gallbladder Polyps: The Role of Current Surgical Indications and Preoperative Images
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Establishing a radiomics model using contrast-enhanced ultrasound for preoperative prediction of neoplastic gallbladder polyps exceeding 10 mm
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European Journal of Medical Research.2025;[Epub] CrossRef
Danning tablets for the treatment of multiple gallbladder polyps: Study protocol of multicentre, randomised, open-labelled, controlled trial
Tian Yang, Ming-Da Wang, Gui-Lin Xie, Xiong-Hua Wang, Liu Zheng, Li-Min Wang, Guang-Fa Xiao, Yong-Qing Yang, Chao Li, Alfred Wei Chieh Kow, Feng Shen
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Endoscopic ultrasound-guided gallbladder endoscopic mucosal resection: a pilot porcine study
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The link between Helicobacter pylori infection and gallbladder and biliary tract diseases: A review
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Annals of Hepato-Biliary-Pancreatic Surgery.2023; 27(3): 241. CrossRef
The gallbladder: what’s new in 2022?
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Abdominal Radiology.2022; 48(1): 2. CrossRef
Gallbladder polyps: diagnosis and treatment tactics (literature review)
S. N. Perekhodov, D. V. Nikolaev, S. S. Saidov
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Is there a role for growth status in distinguishing gallbladder adenomas from cholesterol polyps? – A retrospective study based on 520 cholecystectomy patients
Wenqing Bao, Anan Xu, Shubin Ni, Bo Wang, Humaira Urmi, Bin Zhao, Yongmei You, Hai Hu
Scandinavian Journal of Gastroenterology.2021; 56(12): 1450. CrossRef
Imagerie des tumeurs bénignes des voies biliaires et de la vésicule
J.-P. Tasu, B. Bergougnoux, E. Frouin, S. Velasco, C. Aubé, N. Beydoun
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Polyps and cancer of the biliary system (lecture for medical practitioners)
G. V. Shavkuta
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Obstetrics, Gynecology, and Reproductive Medicine
Classification of endometriosis: Soo-Young Lee, Yu-Jin Koo, Dae-Hyung Lee; Yeungnam Univ J Med. 2021;38(1):10-18. Published online August 7, 2020; DOI: https://doi.org/10.12701/yujm.2020.00444

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Abstract PDF

Endometriosis is a chronic disease associated with pelvic pain and infertility. Several classification systems for the severity of endometriosis have been proposed. Of these, the revised American Society for Reproductive Medicine classification is the most well-known. The ENZIAN classification was developed to classify deep infiltrating endometriosis and focused on the retroperitoneal structures. The endometriosis fertility index was developed to predict the fertility outcomes in patients who underwent surgery for endometriosis. Finally, the American Association of Gynecological Laparoscopists classification is currently being developed, for which 30 endometriosis experts are analyzing and researching data by assigning scores to categories considered important; however, it has not yet been fully validated and published. Currently, none of the classification systems are considered the gold standard. In this article, we review the classification systems, identify their pros and cons, and discuss what improvements need to be made to each system in the future.

Citations

Citations to this article as recorded by

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Analysis of VEGF, IGF1/2 and the Long Noncoding RNA (lncRNA) H19 Expression in Polish Women with Endometriosis
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Shulin Zhong, Yuzhen Liang, Zhixi Wu, Li Wei
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Psychological hallmarks of endometriosis with emphasis on sexual dysfunction, stress, anxiety and depressive symptoms
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Exosomal microRNAs and long noncoding RNAs: as novel biomarkers for endometriosis
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Aki Kido, Yuki Himoto, Yusaku Moribata, Yasuhisa Kurata, Yuji Nakamoto
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Mireille D. Truong, Lauren N. Tholemeier
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NLRP3 activated macrophages promote endometrial stromal cells migration in endometriosis
Feng Zhou, Fanxuan Zhao, Qianmeng Huang, Xiang Lin, Songying Zhang, Yongdong Dai
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European Journal of Obstetrics & Gynecology and Reproductive Biology.2021; 263: 252. CrossRef
Stigma and Endometriosis: A Brief Overview and Recommendations to Improve Psychosocial Well-Being and Diagnostic Delay
Omar T. Sims, Jhumka Gupta, Stacey A. Missmer, Irene O. Aninye
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Physical therapy, Sports Therapy, and Rehabilitation
Updates on the treatment of adhesive capsulitis with hydraulic distension: Jang Hyuk Cho; Yeungnam Univ J Med. 2021;38(1):19-26. Published online August 31, 2020; DOI: https://doi.org/10.12701/yujm.2020.00535

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270 Download
12 Crossref

Abstract PDF

Adhesive capsulitis of the shoulder joint is a common disease characterized by pain at the insertional area of the deltoid muscle and decreased range of motion. The pathophysiological process involves fibrous inflammation of the capsule and intraarticular adhesion of synovial folds leading to capsular thickening and contracture. Regarding the multidirectional limitation of motion, a limitation in external rotation is especially prominent, which is related to not only global fibrosis but also to a localized tightness of the anterior capsule. Ultrasound and magnetic resonance imaging studies can be applied to rule out other structural lesions in the diagnosis of adhesive capsulitis. Hydraulic distension of the shoulder joint capsule provides pain relief and an immediate improvement in range of motion by directly expanding the capsule along with the infusion of steroids. However, the optimal technique for hydraulic distension is still a matter of controversy, with regards to the infusion volume and rupture of the capsule. By monitoring the real-time pressure-volume profile during hydraulic distension, the largest possible fluid volume can be infused without rupturing the capsule. The improvement in clinical outcomes is shown to be greater in capsule-preserved hydraulic distension than in capsule-ruptured distension. Moreover, repeated distension is possible, which provides additional clinical improvement. Capsule-preserved hydraulic distension with maximal volume is suggested to be an efficacious treatment option for persistent adhesive capsulitis.

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Comparing the Efficacy of Intra-articular Platelet-rich Plasma and Corticosteroid Injections in the Management of Adhesive Capsulitis of Shoulder
Suriya Kulothungan Karikalan, Karthik Murugan, Lionel John J
Journal of Orthopedics and Joint Surgery.2025; 7(1): 104. CrossRef
Rotator Interval vs Posterior Approach Ultrasound-guided Corticosteroid Injections in Primary Frozen Shoulder: A Meta-analysis of Randomized Controlled Trials
Francisco Javier Arrambide-Garza, Juventino Tadeo Guerrero-Zertuche, Neri Alejandro Alvarez-Villalobos, Alejandro Quiroga-Garza, Abraham Espinosa-Uribe, Felix Vilchez-Cavazos, Yolanda Salinas-Alvarez, Juan Antonio Rivera-Perez, Rodrigo Enrique Elizondo-Om
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A prospective, randomized, blinded study on the efficacy of using corticosteroids in hydrodilatation as a treatment for adhesive capsulitis of the shoulder
Joan Tomàs Gebellí-Jové, Antonio Buñuel-Viñau, Marta Canela-Capdevila, Jordi Camps, Fàtima Sabench, Petrea Iftimie-Iftimie
Shoulder & Elbow.2024;[Epub] CrossRef
Pharmacoacupuncture for the Treatment of Frozen Shoulder: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Ji-Ho Lee, Hyeon-Sun Park, Sang-Hyeon Park, Yun-Kyung Song, Dong-Ho Keum, Seo-Hyun Park
Current Pain and Headache Reports.2024; 28(12): 1365. CrossRef
Frozen Shoulder: Diagnosis and Management
Sean R. Wise, Paul Seales, Alex P. Houser, Chase B. Weber
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Ultrasound-guided hydrodilatation of glenohumeral joint combined with acupotomy for treatment of frozen shoulder
Huajun Xu, Yingchun Zhang, Caishan Wang
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Impact of capsular preservation on patient-reported outcomes and complication rates in total hip arthroplasty using the direct anterior approach
Vincent A. Stadelmann, Hannes A. Rüdiger, Selina Nauer, Michael Leunig
The Bone & Joint Journal.2022; 104-B(7): 826. CrossRef
Management of Patients with Adhesive Capsulitis via Ultrasound-Guided Hydrodilatation without Concomitant Intra-Articular Lidocaine Infusion: A Single-Center Experience
Yung-Chieh Chen, Shu-Huei Shen, Hong-Jen Chiou, Yung-Liang Wan
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Role of Platelet-Rich Plasma in the Treatment of Adhesive Capsulitis: A Prospective Cohort Study
Syed Imran Haider, Muhammad Zarak Awais, Muhammad Tahir Iqbal
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Musculoskeletal complications in patients with diabetes mellitus
Jong Han Choi, Hae-Rim Kim, Kee-Ho Song
The Korean Journal of Internal Medicine.2022; 37(6): 1099. CrossRef
Comparison of the spread pattern of medial-to-lateral and lateral-to-medial rotator interval injections: A cadaveric study
Benjamin J. Kozlowski, John Tran, Philip W.H. Peng, Anne M.R. Agur, Nimish Mittal
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Updates on Intra-articular Corticosteroid Injection for the Treatment of Adhesive Capsulitis
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Gastroenterology and Hepatology
Pathophysiology and protective approaches of gut injury in critical illness: Chang Yeon Jung, Jung Min Bae; Yeungnam Univ J Med. 2021;38(1):27-33. Published online September 23, 2020; DOI: https://doi.org/10.12701/yujm.2020.00703

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Abstract PDF

The gut is a complex organ that has played an important role in digestion, absorption, endocrine functions, and immunity. The gut mucosal barriers consist of the immunologic barrier and nonimmunologic barrier. During critical illnesses, the gut is susceptible to injury due to the induction of intestinal hyperpermeability. Gut hyperpermeability and barrier dysfunction may lead to systemic inflammatory response syndrome. Additionally, gut microbiota are altered during critical illnesses. The etiology of such microbiome alterations in critical illnesses is multifactorial. The interaction or systemic host defense modulation between distant organs and the gut microbiome is increasingly studied in disease research. No treatment modality exists to significantly enhance the gut epithelial integrity, permeability, or mucus layer in critically ill patients. However, multiple helpful approaches including clinical and preclinical strategies exist. Enteral nutrition is associated with an increased mucosal barrier in animal and human studies. The trophic effects of enteral nutrition might help to maintain the intestinal physiology, prevent atrophy of gut villi, reduce intestinal permeability, and protect against ischemia-reperfusion injury. The microbiome approach such as the use of probiotics, fecal microbial transplantation, and selective decontamination of the digestive tract has been suggested. However, its evidence does not have a high quality. To promote rapid hypertrophy of the small bowel, various factors have been reported, including the epidermal growth factor, membrane permeant inhibitor of myosin light chain kinase, mucus surrogate, pharmacologic vagus nerve agonist, immune-enhancing diet, and glucagon-like peptide-2 as preclinical strategies. However, the evidence remains unclear.

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Gut integrity in intensive care: alterations in host permeability and the microbiome as potential therapeutic targets
Takehiko Oami, Takashi Shimazui, Tetsuya Yumoto, Shunsuke Otani, Yosuke Hayashi, Craig M. Coopersmith
Journal of Intensive Care.2025;[Epub] CrossRef
Limonene Exerts Anti-Inflammatory Effect on LPS-Induced Jejunal Injury in Mice by Inhibiting NF-κB/AP-1 Pathway
Sarmed H. Kathem, Yasameen Sh. Nasrawi, Shihab H. Mutlag, Surya M. Nauli
Biomolecules.2024; 14(3): 334. CrossRef
S2k-Leitlinie Klinische Ernährung in der Hepatologie
Mathias Plauth, Lars Bechmann, Donata Grajecki, Felix Gundling, Ludwig Kramer, Andreas E. Kremer, Monika Rau, Andrea Schneider, Frank Tacke, Ingo van Thiel
Aktuelle Ernährungsmedizin.2024; 49(04): 256. CrossRef
Bacillus licheniformis reverses the environmental ceftriaxone sodium-induced gut microbial dysbiosis and intestinal inflammation in mice
Zhibo Zeng, Wen Yue, Cermon Kined, PengPeng Wang, Ran Liu, Jing Liu, Xinzhu Chen
Ecotoxicology and Environmental Safety.2023; 257: 114890. CrossRef
Severe gastrointestinal injury associated with SARS-CoV-2 infection: Thrombosis or Inflammation?: A retrospective case series study
Henry Robayo-Amortegui, Alex Forero-Delgadillo, Michel Pérez-Garzón, Claudia Poveda-Henao, Conny Muñoz-Claros, Andrea Bayona-Solano, Carlos Orozco, Ricardo Buitrago-Bernal
Medicine.2022; 101(42): e31188. CrossRef
The Gut-Liver Axis in Cholestatic Liver Diseases
Andreas Blesl, Vanessa Stadlbauer
Nutrients.2021; 13(3): 1018. CrossRef
The Role of DAMPS in Burns and Hemorrhagic Shock Immune Response: Pathophysiology and Clinical Issues. Review
Desirè Pantalone, Carlo Bergamini, Jacopo Martellucci, Giovanni Alemanno, Alessandro Bruscino, Gherardo Maltinti, Maximilian Sheiterle, Riccardo Viligiardi, Roberto Panconesi, Tommaso Guagni, Paolo Prosperi
International Journal of Molecular Sciences.2021; 22(13): 7020. CrossRef
Safety of Using Enteral Nutrition Formulations Containing Dietary Fiber in Hospitalized Critical Care Patients: A Systematic Review and Meta‐Analysis
Kelly Copeland Cara, Andrew R. Beauchesne, Taylor C. Wallace, Mei Chung
Journal of Parenteral and Enteral Nutrition.2021; 45(5): 882. CrossRef

Original articles

Obstetrics, Gynecology, and Reproductive Medicine
Association between gestational age at delivery and lymphocyte-monocyte ratio in the routine second trimester complete blood cell count: Hyun-Hwa Cha, Jong Mi Kim, Hyun Mi Kim, Mi Ju Kim, Gun Oh Chong, Won Joon Seong; Yeungnam Univ J Med. 2021;38(1):34-38. Published online June 18, 2020; DOI: https://doi.org/10.12701/yujm.2020.00234

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Abstract PDF

Background
We aimed to determine whether routine second trimester complete blood cell (CBC) count parameters, including neutrophil-lymphocyte ratio (NLR), lymphocyte-monocyte ratio (LMR), and platelet-lymphocyte ratio (PLR), could predict obstetric outcomes.
Methods
We included singleton pregnancies for which the 50-g oral glucose tolerance test and CBC were routinely performed between 24 and 28 weeks of gestation in our outpatient clinic from January 2015 to December 2017. The subjects were divided into three groups according to their pregnancy outcomes as follows: group 1, spontaneous preterm births, including preterm labor and preterm premature rupture of membranes; group 2, indicated preterm birth due to maternal, fetal, or placental causes (hypertensive disorder, fetal growth restriction, or placental abruption); and group 3, term deliveries, regardless of the indication of delivery. We compared the CBC parameters using a bivariate correlation test.
Results
The study included 356 pregnancies. Twenty-eight subjects were in group 1, 20 in group 2, and 308 in group 3. There were no significant differences between the three groups in neutrophil, monocyte, lymphocyte, and platelet counts. Although there was no significant difference in NLR, LMR, and PLR between the three groups, LMR showed a negative correlation with gestational age at delivery (r=−0.126, p=0.016).
Conclusion
We found that a higher LMR in the second trimester was associated with decreased gestational age at delivery. CBC parameters in the second trimester of pregnancy could be used to predict adverse obstetric outcomes.

Citations

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Correlation of maternal platelet to lymphocyte ratio, neutrophil to lymphocyte ratio, C- reactive protein with gestational age at delivery and fetal outcome - A prospective observational study from tertiary care centre
Mrinalini Kannan, Sajeetha Kumari R, Vinodhini Shanmugham
Clinical Epidemiology and Global Health.2024; 28: 101687. CrossRef
The predictive value of thromboelastography, routine blood indices, ultrasound parameters, and placental thickness in determining fetal outcome
Liang Guo
American Journal of Translational Research.2024; 16(7): 3014. CrossRef
Relationship between Platelet-to-Lymphocyte Ratio and Lymphocyte-to-Monocyte Ratio with Spontaneous Preterm Birth: A Systematic Review and Meta-analysis
Liang Peng, Baodi Cao, Fangpeng Hou, Baolin Xu, Hong Zhou, Luyi Liang, Yu Jiang, Xiaohui Wang, Jingjian Zhou, Lingzhang Meng
Journal of Immunology Research.2023; 2023: 1. CrossRef
High Apoptotic Index in Amniotic Membrane of Pregnant Women is A Risk Factor for Preterm Labor
Anak Agung Gede Putra Wiradnyana, Anak Agung Ngurah Jaya Kusuma, Anak Agung Ngurah Anantasika, I Made Darmayasa, Ryan Saktika Mulyana, Gde Bagus Rizky Kornia
European Journal of Medical and Health Sciences.2023; 5(3): 79. CrossRef
Evaluation of Complete Blood Cell Count Parameters in the Diagnosis of Threatened Preterm Labor and Premature Rupture of Membranes
Jule Eriç Horasanlı, Elifsena Canan Alp, Ramazan Bülbül
Dubai Medical Journal.2022; 5(3): 157. CrossRef
The Association of Inflammatory Biomarker of Neutrophil-to-Lymphocyte Ratio with Spontaneous Preterm Delivery: A Systematic Review and Meta-analysis
Sina Vakili, Parham Torabinavid, Reza Tabrizi, Alireza Shojazadeh, Nasrin Asadi, Kamran Hessami, Oleh Andrukhov
Mediators of Inflammation.2021; 2021: 1. CrossRef

Urology
Pelvic floor muscle exercise with biofeedback helps regain urinary continence after robot-assisted radical prostatectomy: Yeong Uk Kim, Dong Gyu Lee, Young Hwii Ko; Yeungnam Univ J Med. 2021;38(1):39-46. Published online June 22, 2020; DOI: https://doi.org/10.12701/yujm.2020.00276

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Abstract PDF

Background
To determine the benefit of pelvic floor muscle exercise with visual biofeedback on promoting patient recovery from incontinence, we investigated variables associated with the early restoration of continence for patients who underwent robot-assisted radical prostatectomy.
Methods
Of the 83 patients enrolled, 41 consecutive patients completed pelvic floor muscle exercise (the exercise group), and the other 42 consecutive patients just before the pelvic floor muscle exercise program commenced (the control group). The primary outcome was whether pelvic floor muscle exercise engagement was associated with zero pad continence restoration within 3 months of surgery.
Results
Continence restoration percentages (defined as zero pads used per day) at 1, 3, and 6 months after surgery were 49.4%, 77.1%, and 94.0%, respectively. The exercise group achieved significantly higher recovery rates at 1 month (p=0.037), 3 months (p<0.001), and 6 months (p=0.023). Cox regression analysis demonstrated that a lower Gleason score (<8; hazard ratio, 2.167), lower prostate specific antigen (<20 ng/dL; hazard ratio, 2.909), and engagement in pelvic floor muscle exercise (hazard ratio, 3.731) were independent predictors of early recovery from postprostatectomy incontinence. Stratification by age showed that those younger than 65 years did not benefit significantly from exercise (log-rank test, p=0.08), but that their elderly counterparts, aged 65–70 years (p=0.007) and >70 years old (p=0.002) benefited significantly.
Conclusion
This study suggests that postoperative engagement in pelvic floor muscle exercise with biofeedback speeds up the recovery of continence in elderly patients (≥65 years old) that undergo robot-assisted radical prostatectomy.

Citations

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Urinary incontinence rehabilitation of after radical prostatectomy: a systematic review and network meta-analysis
Kai Yu, Fan Bu, Tengteng Jian, Zejun Liu, Rui Hu, Sunmeng Chen, Ji Lu
Frontiers in Oncology.2024;[Epub] CrossRef
Factors influencing engagement in pelvic floor muscle exercise following radical prostatectomy: A scoping review
Yousef Qan'ir, Lixin Song, Kathleen Knafl, Paschal Sheeran, Hung‐Jui Tan, Mohammed Shahait, Ahmad AL‐Sagarat
International Journal of Urological Nursing.2024;[Epub] CrossRef
Pelvic floor muscle training in men with post-prostatectomy urinary incontinence: a scoping review
Jackelline Evellin Moreira dos Santos, Virginia Visconde Brasil, Cissa Azevedo, Lívia Cristina de Resende Izidoro, Anna Julia Guimarães Batista, André Carlos Santos Ferreira, Luciana Regina Ferreira da Mata
Revista Latino-Americana de Enfermagem.2024;[Epub] CrossRef
Entrenamiento de los músculos del piso pélvico en hombres con incontinencia urinaria post prostatectomía: revisión de alcance
Jackelline Evellin Moreira dos Santos, Virginia Visconde Brasil, Cissa Azevedo, Lívia Cristina de Resende Izidoro, Anna Julia Guimarães Batista, André Carlos Santos Ferreira, Luciana Regina Ferreira da Mata
Revista Latino-Americana de Enfermagem.2024;[Epub] CrossRef
Treinamento dos músculos do assoalho pélvico em homens com incontinência urinária pós-prostatectomia: revisão do escopo
Jackelline Evellin Moreira dos Santos, Virginia Visconde Brasil, Cissa Azevedo, Lívia Cristina de Resende Izidoro, Anna Julia Guimarães Batista, André Carlos Santos Ferreira, Luciana Regina Ferreira da Mata
Revista Latino-Americana de Enfermagem.2024;[Epub] CrossRef
Single Session Pre-Operative Pelvic Floor Muscle Training with Biofeedback on Urinary Incontinence and Quality of Life after Radical Prostatectomy
Mohammad-Hatef Khorrami, Amir Mohseni, Farshad Gholipour, Farshid Alizadeh, Mahtab Zargham, Mohammad-Hossein Izadpanahi, Mehrdad Mohammadi Sichani, Farbod Khorrami
Urological Science.2023; 34(1): 23. CrossRef
Effect of Kegel exercises on the prevention of urinary and fecal incontinence in patients with prostate cancer undergoing radiotherapy
A.E. Urvaylıoğlu, S. Kutlutürkan, D. Kılıç
European Journal of Oncology Nursing.2021; 51: 101913. CrossRef

Dentistry
Evaluation of craniofacial morphology in short-statured children: growth hormone deficiency versus idiopathic short stature: Ki Bong Kim, Eun-Kyong Kim, Kyung Mi Jang, Min Seon Kim, Eun Young Park; Yeungnam Univ J Med. 2021;38(1):47-52. Published online July 7, 2020; DOI: https://doi.org/10.12701/yujm.2020.00325

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Abstract PDF

Background
Short stature is defined as a height below the 3rd percentile or more than two standard deviations below the mean for a given age, sex, and population. There have been inconsistent results regarding craniofacial morphology in short-statured children. This study aimed to analyze the differences between short-statured children with growth hormone deficiency, idiopathic short-statured children, and normal children.
Methods
Thirty-one short-statured children with growth hormone deficiency, 32 idiopathic short-statured children, and 32 healthy children were enrolled in this study. The measurements of their craniofacial structures from lateral cephalograms were evaluated.
Results
There were statistically significant differences among the three groups seven variables (anterior cranial base length, posterior cranial base length, total cranial base length, upper posterior facial height, posterior total facial height, mandibular ramus length, and overall mandibular length) in the linear measurement and five variables (saddle angle, gonial angle, mandibular plane angle, position of mandible, and maxilla versus mandible) in the angular measurement.
Conclusion
Compared to the control group, many linear and angular measurements of the craniofacial structures were significantly different in the two short-statured groups (p<0.05). Treatment plans by orthodontists should include these craniofacial structure characteristics.

Citations

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Dental arches in inherited severe isolated growth hormone deficiency
Rafaela S. Girão, Manuel H. Aguiar-Oliveira, Bruna M.R. Andrade, Marcos A.V. Bittencourt, Roberto Salvatori, Evânio V. Silva, André L.M. Santos, Matheus M. Cunha, Wilton M. Takeshita, Alaíde H.A. Oliveira, Eugênia H.O. Valença, Alécia A. Oliveira-Santos,
Growth Hormone & IGF Research.2022; 62: 101444. CrossRef
Sella turcica dimensions and maxillary growth in patients with unilateral cleft lip and palate
Gregory S. Antonarakis, Luis Huanca Ghislanzoni, David M. Fisher
Journal of Stomatology, Oral and Maxillofacial Surgery.2022; 123(6): e916. CrossRef
Clinical Implications of Growth Hormone Deficiency for Oral Health in Children: A Systematic Review
Natalia Torlińska-Walkowiak, Katarzyna Anna Majewska, Andrzej Kędzia, Justyna Opydo-Szymaczek
Journal of Clinical Medicine.2021; 10(16): 3733. CrossRef
A Clinical Study on the Treatment of Children’s Short Stature with Auxiliary Comprehensive Management Combined with Growth Patch
Haiying Feng, Weizhu Zhao, Huijun Yu, Guanfu Wang, Qunhong Wang, Songwen Tan
Evidence-Based Complementary and Alternative Medicine.2021; 2021: 1. CrossRef

Obstetrics, Gynecology, and Reproductive Medicine
Effect of in vitro testicular spermatozoa culture on pregnancy outcomes: an experience at a single university hospital: Jisun Lee, Jung Hyeon Yoo, Jae Hun Lee, Hyun Soo Ahn, Kyung Joo Hwang, Miran Kim; Yeungnam Univ J Med. 2021;38(1):53-59. Published online December 9, 2020; DOI: https://doi.org/10.12701/yujm.2020.00773

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Abstract PDF

Background
There are no guidelines for the optimal incubation time or temperature to improve pregnancy outcomes in testicular sperm extraction-intracytoplasmic sperm injection (TESE-ICSI) cycles. We aimed to evaluate whether a 24-hour in vitro culture of testicular spermatozoa affects pregnancy outcomes in TESE-ICSI cycles.
Methods
This was a retrospective study of 83 TESE-ICSI cycles using testicular spermatozoa in 46 couples with male partners suffering from nonobstructive or obstructive azoospermia. Sperm retrieval was performed either on the oocyte retrieval (OR) day (65 cycles in 33 couples; group A) or on the day before OR (18 cycles in 13 couples; group B) followed by in vitro culture for 24 hours. The clinical characteristics and pregnancy outcomes, including the number of retrieved oocytes, fertilization rates, embryo transfer rates, implantation and clinical pregnancy rates, were compared between the two groups.
Results
There were no differences in terms of clinical characteristics except for the levels of luteinizing hormone (LH) in males. Group B had higher LH levels than group A (4.56±1.24 IU/L vs. 3.67±1.07 IU/L, p=0.017). Group B showed higher fertilization rate (72.4±32.1% vs. 59.2±21.7%, p=0.045), implantation rate (35.0±34.1% vs. 14.0±21.5%, p=010), pregnancy rate per cycle (80% vs. 39%, p=0.033), and clinical pregnancy rate per cycle (80% vs. 37.5%, p=0.024) than those of group A.
Conclusion
Testicular sperm retrieval performed on the day before OR followed by in vitro culture can potentially improve pregnancy outcomes.

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Timing of Testicular Biopsy in Relation to Oocyte Retrieval and the Outcomes of Intracytoplasmic Sperm Injection
Lily Ng, Olena M. Kocur, Philip Xie, Stephanie Cheung, Peter Schlegel, Zev Rosenwaks, Gianpiero D. Palermo
Journal of Urology.2024; 211(5): 678. CrossRef
Intelligent Medicine on the Regulation Effect of Weekend Catch-Up Sleep on the Relationship Between Hypertension and All-Cause Mortality
Hui Li, Min Yang, Yanchun Bao
International Journal of Computational Intelligence Systems.2023;[Epub] CrossRef
Extend the Survival of Human Sperm In Vitro in Non-Freezing Conditions: Damage Mechanisms, Preservation Technologies, and Clinical Applications
Qingyuan Cheng, Liman Li, Min Jiang, Bo Liu, Yang Xian, Shasha Liu, Xiao Liu, Wenrui Zhao, Fuping Li
Cells.2022; 11(18): 2845. CrossRef

Case reports

Endocrinology, Diabetes, and Metabolism
Cushing syndrome in pregnancy, diagnosed after delivery: Han Byul Kim, Mi Kyung Kim, El Kim, Keun Soo Ahn, Hye Soon Kim, Nam Kyung Kim; Yeungnam Univ J Med. 2021;38(1):60-64. Published online May 22, 2020; DOI: https://doi.org/10.12701/yujm.2020.00290

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Abstract PDF

Cushing syndrome (CS) is rare in pregnancy, and few cases have been reported to date. Women with untreated CS rarely become pregnant because of the ovulatory dysfunction induced by hypercortisolism. It is difficult to diagnose CS in pregnancy because of its very low incidence, the overlap between the clinical signs of hypercortisolism and the physiological changes that occur during pregnancy and the changes in hypothalamus-pituitary-adrenal axis activity that occur during pregnancy and limit the value of standard diagnostic testing. However, CS in pregnancy is associated with poor maternal and fetal outcomes; therefore, its early diagnosis and treatment are important. Here, we report two patients with CS that was not diagnosed during pregnancy, in whom maternal and fetal morbidity developed because of hypercortisolism.

Citations

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Cushing’s disease with twin pregnancy and diabetes mellitus: a case report and literature review
Hideyasu Asai, Ikuo Yamamori, Shigeru Hagimoto, Kyoichi Okumura, Koki Sakakibara
Endocrine Journal.2024; 71(10): 1003. CrossRef
Endogenous Cushing’s syndrome during pregnancy
Nada Younes, Matthieu St-Jean, Isabelle Bourdeau, André Lacroix
Reviews in Endocrine and Metabolic Disorders.2023; 24(1): 23. CrossRef
Cushing Syndrome in Pregnancy: A Case Presentation and Review of Literature
HamidReza Samimagham, Ava Ziaei, Mohammad Tamaddondar, Mitra Kazemi Jahromi
Journal of Kermanshah University of Medical Sciences.2023;[Epub] CrossRef

Nephrology
Development of donepezil-induced hypokalemia following treatment of cognitive impairment: Dongryul Kim, Hye Eun Yoon, Hoon Suk Park, Seok Joon Shin, Bum Soon Choi, Byung Soo Kim, Tae Hyun Ban; Yeungnam Univ J Med. 2021;38(1):65-69. Published online June 1, 2020; DOI: https://doi.org/10.12701/yujm.2020.00269

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Abstract PDF

Donepezil is a cholinesterase inhibitor used extensively to treat Alzheimer disease. The increased cholinergic activity is associated with adverse effects, therefore gastrointestinal symptoms, including nausea, vomiting, and diarrhea, are common. Hypokalemia is a rare adverse event that occurs in less than 1% of donepezil-treated patients. Although hypokalemia of mild and moderate grade does not present serious signs and symptoms, severe hypokalemia often results in prolonged hospitalization and mortality. Herein, we report a case of hypokalemia developed after the initiation of donepezil therapy for cognitive impairment.

Citations

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Thymus vulgaris Essential Oil Protects Zebrafish against Cognitive Dysfunction by Regulating Cholinergic and Antioxidants Systems
Luminita Capatina, Elena Todirascu-Ciornea, Edoardo Marco Napoli, Giuseppe Ruberto, Lucian Hritcu, Gabriela Dumitru
Antioxidants.2020; 9(11): 1083. CrossRef

Gastroenterology and Hepatology
Co-existence of relapsing polychondritis and Crohn disease treated successfully with infliximab: Hye-In Jung, Hyun Jung Kim, Ji-Min Kim, Ju Yup Lee, Kyung Sik Park, Kwang Bum Cho, Yoo Jin Lee; Yeungnam Univ J Med. 2021;38(1):70-73. Published online June 19, 2020; DOI: https://doi.org/10.12701/yujm.2020.00304

6,501 View
101 Download
2 Crossref

Abstract PDF

Relapsing polychondritis (RP) is a rare, progressive immune-mediated systemic inflammatory disease of unknown etiology, characterized by recurrent inflammation of cartilaginous structures. Approximately 30% of RP cases are associated with other autoimmune diseases. However, the co-occurrence of RP and Crohn disease (CD) has rarely been reported. Herein, we present a 35-year-old woman diagnosed with RP and CD, who was refractory to initial conventional medications, including azathioprine and glucocorticoid, but who subsequently responded to infliximab (IFX). For both diseases, remission was sustained with IFX. There has been no previous report regarding the successful treatment of co-existing RP and CD with IFX.

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Coexistence of Relapsing Polychondritis, Crohn's Disease, and Pyoderma Gangrenosum Treated Successfully with Adalimumab: A Case Report and Literature Review
Shun Yamazaki, Kentaro Tominaga, Kotaro Watanabe, Makoto Watanabe, Shuhei Kondo, Norihiro Sakai, Tomoaki Yoshida, Yuichi Kojima, Yusuke Watanabe, Yuzo Kawata, Naruhiro Kimura, Kazuya Takahashi, Hiroki Sato, Satoshi Ikarashi, Hiroteru Kamimura, Kazunao Hay
Internal Medicine.2025;[Epub] CrossRef
Relapsing Polychondritis in a Patient With Auricular Chondritis and Inflammatory Bowel Disease: A Case Report With Literature Review
David D Bickford, Thomas Ritter, Pinky Jha, Hari R Paudel
Cureus.2022;[Epub] CrossRef

Radiology, Radiotherapy & Diagnostic Imaging
Transpedal lymphatic embolization for lymphorrhea at the graft harvest site after coronary artery bypass grafting: Jung Guen Cha, Sang Yub Lee, Jihoon Hong, Hun Kyu Ryeom, Gab Chul Kim, Young Woo Do; Yeungnam Univ J Med. 2021;38(1):74-77. Published online July 20, 2020; DOI: https://doi.org/10.12701/yujm.2020.00297

5,798 View
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Abstract PDF

Lymphorrhea is a rare but potentially severe complication that occurs after various surgical procedures. Untreated lymphorrhea may lead to wound dehiscence, infection, and prolonged hospital stay. Currently, there is no standard effective treatment. Early management usually includes leg elevation, drainage, and pressure dressing. However, these methods are associated with prolonged recovery and high recurrence rates. We report a case of lymphorrhea from a calf wound after endoscopic great saphenous vein (GSV) harvesting for coronary artery bypass grafting (CABG). The patient presented with intractable oozing from the postoperative wound on the right calf. Lymphorrhea perGsisted for 6 weeks despite negative-pressure wound therapy with a long-acting somatostatin. We performed unilateral pedal lymphangiography that confirmed wound lymphorrhea, followed by glue embolization. No recurrence was observed after 8 months of follow-up. This case report demonstrates the successful use of lymphangiography with glue embolization in the control of lymphorrhea after GSV harvesting for CABG.

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Sei Yoshida, Hideki Kadota, Kentaro Anan, Nobuaki Hatakeyama
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Update February 2021
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Lymphatic complications after harvesting venous conduits in coronary artery bypass grafting surgery
D. V. Manvelyan, Yu. Y. Vechersky, V. V. Zatolokin, M. S. Kuznetsov, B. N. Kozlov
The Siberian Journal of Clinical and Experimental Medicine.2021; 36(3): 27. CrossRef

Radiology, Radiotherapy & Diagnostic Imaging
Pancreatic metastasis from malignant phyllodes tumor of the breast: Seung Eun Lee, Young Kyung Bae, Joon Hyuk Choi; Yeungnam Univ J Med. 2021;38(1):78-82. Published online November 27, 2020; DOI: https://doi.org/10.12701/yujm.2020.00759

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Abstract PDF

Pancreatic metastasis from malignant phyllodes tumor (PT) of the breast is rare, and only a few cases have been reported in the literature. Here, we report a case of pancreatic metastasis from malignant PT of the breast in a 48-year-old woman. She had had three episodes of recurrence of malignant PT in her right breast. She presented with epigastric pain for 2 months. Computed tomography and magnetic resonance imaging revealed a 6 cm-sized, well-defined, heterogeneous mass with peripheral enhancement in the body of the pancreas. Endoscopic ultrasonography-guided fine-needle aspiration was performed, and the pathologic report suggested spindle cell mesenchymal neoplasm. Subsequently, surgical excision was performed, and the mass was confirmed as a metastatic malignant PT. The imaging findings are discussed and the literature is briefly reviewed in this report.

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