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JYMS : Journal of Yeungnam Medical Science

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Articles in E-pub version are posted online ahead of regular printed publication.

Review article
Clinical significance of exosomal noncoding RNAs in hepatocellular carcinoma: a narrative review
Jae Sung Yoo, Min Kyu Kang
Received October 30, 2023  Accepted December 30, 2023  Published online February 8, 2024  
DOI: https://doi.org/10.12701/jyms.2023.01186    [Epub ahead of print]
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AbstractAbstract PDF
Hepatocellular carcinoma (HCC) is one of the most lethal malignancies worldwide, with poor prognosis owing to its high frequency of recurrence and metastasis. Moreover, most patients are diagnosed at an advanced stage owing to a lack of early detection markers. Exosomes, which are characterized by their cargos of stable intracellular messengers, such as DNA, RNA, proteins, and lipids, play a crucial role in regulating cell differentiation and HCC development. Recently, exosomal noncoding RNAs (ncRNAs), including microRNAs, long ncRNAs, and circular RNAs, have become increasingly important diagnostic, prognostic, and predictive markers of HCC. Herein, we discuss the clinical implications of exosomal ncRNAs, specifically those within the HCC regulatory network.
Imagerys
Cosmos in full autumn
Published online January 24, 2024  
DOI: https://doi.org/10.12701/jyms.2024.00052    [Epub ahead of print]
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Trumpet creepers in summer alleyway
Published online January 24, 2024  
DOI: https://doi.org/10.12701/jyms.2024.00045    [Epub ahead of print]
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JYMS : Journal of Yeungnam Medical Science