Journal of Yeungnam Medical Science

Most-download articles are from the articles published in 2021 during the last 3 months.

Focused Review articles

The pathophysiology of diabetic foot: a narrative review: Jiyoun Kim; J Yeungnam Med Sci. 2023;40(4):328-334. Published online October 5, 2023; DOI: https://doi.org/10.12701/jyms.2023.00731

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An aging population and changes in dietary habits have increased the incidence of diabetes, resulting in complications such as diabetic foot ulcers (DFUs). DFUs can lead to serious disabilities, substantial reductions in patient quality of life, and high financial costs for society. By understanding the etiology and pathophysiology of DFUs, their occurrence can be prevented and managed more effectively. The pathophysiology of DFUs involves metabolic dysfunction, diabetic immunopathy, diabetic neuropathy, and angiopathy. The processes by which hyperglycemia causes peripheral nerve damage are related to adenosine triphosphate deficiency, the polyol pathway, oxidative stress, protein kinase C activity, and proinflammatory processes. In the context of hyperglycemia, the suppression of endothelial nitric oxide production leads to microcirculation atherosclerosis, heightened inflammation, and abnormal intimal growth. Diabetic neuropathy involves sensory, motor, and autonomic neuropathies. The interaction between these neuropathies forms a callus that leads to subcutaneous hemorrhage and skin ulcers. Hyperglycemia causes peripheral vascular changes that result in endothelial cell dysfunction and decreased vasodilator secretion, leading to ischemia. The interplay among these four preceding pathophysiological factors fosters the development and progression of infections in individuals with diabetes. Charcot neuroarthropathy is a chronic and progressive degenerative arthropathy characterized by heightened blood flow, increased calcium dissolution, and repeated minor trauma to insensate joints. Directly and comprehensively addressing the pathogenesis of DFUs could pave the way for the development of innovative treatment approaches with the potential to avoid the most serious complications, including major amputations.

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Unveiling the challenges of diabetic foot infections: diagnosis, pathogenesis, treatment, and rehabilitation
Chul Hyun Park
Journal of Yeungnam Medical Science.2023; 40(4): 319. CrossRef

Management of diabetic foot ulcers: a narrative review: Jahyung Kim, Otgonsaikhan Nomkhondorj, Chi Young An, Ye Chan Choi, Jaeho Cho; J Yeungnam Med Sci. 2023;40(4):335-342. Published online September 22, 2023; DOI: https://doi.org/10.12701/jyms.2023.00682

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Abstract PDF

Diabetic foot ulcers (DFUs) are among the most serious complications of diabetes and are a source of reduced quality of life and financial burden for the people involved. For effective DFU management, an evidence-based treatment strategy that considers the patient's clinical context and wound condition is required. This treatment strategy should include conventional practices (surgical debridement, antibiotics, vascular assessment, offloading, and amputation) coordinated by interdisciplinary DFU experts. In addition, several adjuvant therapies can be considered for nonhealing wounds. In this narrative review, we aim to highlight the current trends in DFU management and review the up-to-date guidelines.

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Unveiling the challenges of diabetic foot infections: diagnosis, pathogenesis, treatment, and rehabilitation
Chul Hyun Park
Journal of Yeungnam Medical Science.2023; 40(4): 319. CrossRef

Review article

Multidisciplinary approach to sarcopenia: a narrative review: Wook Tae Park, Oog-Jin Shon, Gi Beom Kim; J Yeungnam Med Sci. 2023;40(4):352-363. Published online September 7, 2023; DOI: https://doi.org/10.12701/jyms.2023.00724

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Abstract PDF: Sarcopenia is a condition in which muscle mass and strength are decreased and muscle function is impaired. It is an indicator of frailty and loss of independence in older adults. It is also associated with increased physical disability, which increases the risk of falls. As a multifactorial disease, sarcopenia is caused by a combination of factors including aging, hormonal changes, nutritional deficiencies, and physical inactivity. Understanding the underlying pathophysiology of sarcopenia and identifying its different causes is critical to developing effective prevention and treatment strategies. This review summarizes the pathophysiology, consequences, diagnostic methods, and multidisciplinary approaches to sarcopenia.

Focused Review article

Management and rehabilitation of moderate-to-severe diabetic foot infection: a narrative review: Chi Young An, Seung Lim Baek, Dong-Il Chun; J Yeungnam Med Sci. 2023;40(4):343-351. Published online September 19, 2023; DOI: https://doi.org/10.12701/jyms.2023.00717

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Abstract PDF

Diabetic foot is one of the most devastating consequences of diabetes, resulting in amputation and possibly death. Therefore, early detection and vigorous treatment of infections in patients with diabetic foot are critical. This review seeks to provide guidelines for the therapy and rehabilitation of patients with moderate-to-severe diabetic foot. If a diabetic foot infection is suspected, bacterial cultures should be initially obtained. Numerous imaging studies can be used to identify diabetic foot, and recent research has shown that white blood cell single-photon emission computed tomography/computed tomography has comparable diagnostic specificity and sensitivity to magnetic resonance imaging. Surgery is performed when a diabetic foot ulcer is deep and is accompanied by bone and soft tissue infections. Patients should be taught preoperative rehabilitation before undergoing stressful surgery. During surgical procedures, it is critical to remove all necrotic tissue and drain the inflammatory area. It is critical to treat wounds with suitable dressings after surgery. Wet dressings promote the formation of granulation tissues and new blood vessels. Walking should begin as soon as the patient’s general condition allows it, regardless of the wound status or prior walking capacity. Adequate treatment of comorbidities, including hypertension and dyslipidemia, and smoking cessation are necessary. Additionally, broad-spectrum antibiotics are required to treat diabetic foot infections.

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Unveiling the challenges of diabetic foot infections: diagnosis, pathogenesis, treatment, and rehabilitation
Chul Hyun Park
Journal of Yeungnam Medical Science.2023; 40(4): 319. CrossRef

Review article

Psychiatric understanding and treatment of patients with amputations: So-Hye Jo, Suk-Hun Kang, Wan-Seok Seo, Bon-Hoon Koo, Hye-Geum Kim, Seok-Ho Yun; Yeungnam Univ J Med. 2021;38(3):194-201. Published online May 11, 2021; DOI: https://doi.org/10.12701/yujm.2021.00990

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Abstract PDF

Amputation changes the lives of patients and their families. Consequently, the patient must adapt to altered body function and image. During this adaptation process, psychological problems, such as depression, anxiety, and posttraumatic stress disorder, can occur. The psychological difficulties of patients with amputation are often accepted as normal responses that are often poorly recognized by patients, family members, and their primary physicians. Psychological problems can interfere with rehabilitation and cause additional psychosocial problems. Therefore, their early detection and treatment are important. A multidisciplinary team approach, including mental health professionals, is ideal for comprehensive and biopsychosocial management. Mental health professionals could help patients set realistic goals and use adaptive coping styles. Psychiatric approaches should consider the physical, cognitive, psychological, social, and spiritual functions and social support systems before and after amputation. The abilities and limitations of physical, cognitive, psychological, and social functions should also be considered. To improve the patient’s adaptation, psychological interventions such as short-term psychotherapy, cognitive behavioral therapy, mindfulness meditation, biofeedback, and group psychotherapy can be helpful.

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Effect of Increasing Assistance From a Powered Prosthesis on Weight-Bearing Symmetry, Effort, and Speed During Stand-Up in Individuals With Above-Knee Amputation
Grace R. Hunt, Sarah Hood, Lukas Gabert, Tommaso Lenzi
IEEE Transactions on Neural Systems and Rehabilitation Engineering.2023; 31: 11. CrossRef
The Effect of Motivational Interview-Based Counseling in Individuals With Amputation: A Randomized Controlled Trial in Turkey
Gülhan Küçük Öztürk, Nuray Şimşek
Rehabilitation Nursing.2023; 48(5): 160. CrossRef
Psychosocial patient perspectives following major lower-limb amputation due to vascular aetiology: a protocol for a systematic meta-aggregation study
Sisse Heiden Laursen, Helle Lund Rasmussen, Dinnie Seidelin, Peter Hørslev Pedersen, Tanja Mortensen Chræmmer
BMJ Open.2023; 13(9): e076794. CrossRef
Quality of life following non-dysvascular lower limb amputation is contextualized through occupations: a qualitative study
Stephanie R. Cimino, Sander L. Hitzig, Vera Fung, Katie N. Dainty, Crystal MacKay, Joanna E. M. Sale, Amanda L. Mayo, Sara J. T. Guilcher
Disability and Rehabilitation.2023; : 1. CrossRef
Finger prosthesis: A novel way to restore the form, function, and esthetics
Nagaveni S. Somayaji, Pallawi Sinha, Jitendra Sharan, Jagadish Prasad Rajaguru, Anand Marya
Clinical Case Reports.2023;[Epub] CrossRef
Predicting amputation using machine learning: A systematic review
Patrick Fangping Yao, Yi David Diao, Eric P. McMullen, Marlin Manka, Jessica Murphy, Celina Lin, Noman Naseer
PLOS ONE.2023; 18(11): e0293684. CrossRef
Understanding Gangrene in the Context of Peripheral Vascular Disease: Prevalence, Etiology, and Considerations for Amputation-Level Determination
Abhilasha Bhargava, Chandrashekhar Mahakalkar, Shivani Kshirsagar
Cureus.2023;[Epub] CrossRef

Focused Review article

State-of-the-art update for diagnosing diabetic foot osteomyelitis: a narrative review: Inha Woo, Seung Jae Cho, Chul Hyun Park; J Yeungnam Med Sci. 2023;40(4):321-327. Published online October 12, 2023; DOI: https://doi.org/10.12701/jyms.2023.00976

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Abstract PDF

Recently, the International Working Group on the Diabetic Foot and the Infectious Diseases Society of America divided diabetic foot disease into diabetic foot infection (DFI) and diabetic foot osteomyelitis (DFO). DFI is usually diagnosed clinically, while numerous methods exist to diagnose DFO. In this narrative review, the authors aim to summarize the updated data on the diagnosis of DFO. An extensive literature search using “diabetic foot [MeSH]” and “osteomyelitis [MeSH]” or “diagnosis” was performed using PubMed and Google Scholar in July 2023. The possibility of DFO is based on inflammatory clinical signs, including the probe-to-bone (PTB) test. Elevated inflammatory biochemical markers, especially erythrocyte sedimentation rate, are beneficial. Distinguishing abnormal findings of plain radiographs is also a first-line approach. Moreover, sophisticated modalities, including magnetic resonance imaging and nuclear medicine imaging, are helpful if doubt remains after a first-line diagnosis. Transcutaneous bone biopsy, which does not pass through the wound, is necessary to avoid contaminating the sample. This review focuses on the current diagnostic techniques for DFOs with an emphasis on the updates. To obtain the correct therapeutic results, selecting a proper option is necessary. Based on these numerous diagnosis modalities and indications, the proper choice of diagnostic tool can have favorable treatment outcomes.

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Unveiling the challenges of diabetic foot infections: diagnosis, pathogenesis, treatment, and rehabilitation
Chul Hyun Park
Journal of Yeungnam Medical Science.2023; 40(4): 319. CrossRef

Review articles

Long-term management of Graves disease: a narrative review: Hyo-Jeong Kim; J Yeungnam Med Sci. 2023;40(1):12-22. Published online November 4, 2022; DOI: https://doi.org/10.12701/jyms.2022.00444

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Abstract PDF

Graves disease (GD) is the most common cause of hyperthyroidism, accounting for more than 90% of cases in Korea. Patients with GD are treated with any of the following: antithyroid drugs (ATDs), radioactive iodine (RAI) therapy, or thyroidectomy. Most patients begin treatment with ATDs, and clinical guidelines suggest that the appropriate treatment period is 12 to 18 months. While RAI treatment and surgery manage thyrotoxicosis by destroying or removing thyroid tissue, ATDs control thyrotoxicosis by inhibiting thyroid hormone synthesis and preserving the thyroid gland. Although ATDs efficiently control thyrotoxicosis symptoms, they do not correct the main etiology of GD; therefore, frequent relapses can follow. Recently, a large amount of data has been collected on long-term ATDs for GD, and low-dose methimazole (MMZ) is expected to be a good option for remission. For the long-term management of recurrent GD, it is important to induce remission by evaluating the patient’s drug response, stopping ATDs at an appropriate time, and actively switching to surgery or RAI therapy, if indicated. Continuing drug treatment for an extended time is now encouraged in patients with a high possibility of remission with low-dose MMZ. It is also important to pay attention to the quality of life of the patients. This review aimed to summarize the appropriate treatment methods and timing of treatment transition in patients who relapsed several times while receiving treatment for GD.

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Total Thyroidectomy – A Cost-effective Alternative to Anti-Thyroid Drugs in the Management of Grave's Disease
Erivelto Volpi, Leonardo M. Volpi
Clinical Thyroidology.2023; 35(5): 183. CrossRef
Evaluation of the Abbott Alinity i Thyroid-Stimulating Hormone Receptor Antibody (TRAb) Chemiluminescent Microparticle Immunoassay (CMIA)
Deborah J. W. Lee, Soon Kieng Phua, Yali Liang, Claire Chen, Tar-Choon Aw
Diagnostics.2023; 13(16): 2707. CrossRef
Mechanisms and Treatment Options for Hyperthyroid-Induced Osteoporosis: A Narrative Review
Robert M Branstetter, Rahib K Islam, Collin A Toups, Amanda N Parra, Zachary Lee, Shahab Ahmadzadeh, Giustino Varrassi, Sahar Shekoohi, Alan D Kaye
Cureus.2023;[Epub] CrossRef

Beneficial effects of intermittent fasting: a narrative review: Dae-Kyu Song, Yong-Woon Kim; J Yeungnam Med Sci. 2023;40(1):4-11. Published online April 4, 2022; DOI: https://doi.org/10.12701/jyms.2022.00010

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Abstract PDF

Caloric restriction is a popular approach to treat obesity and its associated chronic illnesses but is difficult to maintain for a long time. Intermittent fasting is an alternative and easily applicable dietary intervention for caloric restriction. Moreover, intermittent fasting has beneficial effects equivalent to those of caloric restriction in terms of body weight control, improvements in glucose homeostasis and lipid profiles, and anti-inflammatory effects. In this review, the beneficial effects of intermittent fasting are discussed.

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Maternal intermittent fasting deteriorates offspring metabolism via suppression of hepatic mTORC1 signaling
Wenzhen Yin, Lijun Sun, Yuan Liang, Chao Luo, Tiange Feng, Yunhua Zhang, Weizhen Zhang, Yue Yin
The FASEB Journal.2023;[Epub] CrossRef
Time-Restricted Feeding and Intermittent Fasting as Preventive Therapeutics: A Systematic Review of the Literature
Arturo P Jaramillo, Javier Castells, Sabina Ibrahimli, Luisa Jaramillo, Rebeca R Briones Andriuoli, Denisse Moncada, Jhoanny C Revilla
Cureus.2023;[Epub] CrossRef

Current diagnosis and treatment of vestibular neuritis: a narrative review: Chang Hoon Bae, Hyung Gyun Na, Yoon Seok Choi; J Yeungnam Med Sci. 2022;39(2):81-88. Published online August 9, 2021; DOI: https://doi.org/10.12701/yujm.2021.01228

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6 Citations

Abstract PDF

Vertigo is the sensation of self-motion of the head or body when no self-motion is occurring or the sensation of distorted self-motion during an otherwise normal head movement. Representative peripheral vertigo disorders include benign paroxysmal positional vertigo, Ménière disease, and vestibular neuritis. Vestibular neuritis, also known as vestibular neuronitis, is the third most common peripheral vestibular disorder after benign paroxysmal positional vertigo and Ménière disease. The cause of vestibular neuritis remains unclear. However, a viral infection of the vestibular nerve or ischemia of the anterior vestibular artery is known to cause vestibular neuritis. In addition, recent studies on immune-mediated mechanisms as the cause of vestibular neuritis have been reported. The characteristic clinical features of vestibular neuritis are abrupt true-whirling vertigo lasting for more than 24 hours, and no presence of cochlear symptoms and other neurological symptoms and signs. To accurately diagnose vestibular neuritis, various diagnostic tests such as the head impulse test, bithermal caloric test, and vestibular-evoked myogenic potential test are conducted. Various treatments for vestibular neuritis have been reported, which are largely divided into symptomatic therapy, specific drug therapy, and vestibular rehabilitation therapy. Symptomatic therapies include generalized supportive care and administration of vestibular suppressants and antiemetics. Specific drug therapies include steroid therapy, antiviral therapy, and vasodilator therapy. Vestibular rehabilitation therapies include generalized vestibular and customized vestibular exercises.

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Vertigo in the Setting of COVID-19 Infection: A Case Report
Sanjana Devaragudi, Mohit Gupta
Cureus.2023;[Epub] CrossRef
Hospital Admission Profile Related to Inner Ear Diseases in England and Wales
Esra’ O. Taybeh, Abdallah Y. Naser
Healthcare.2023; 11(10): 1457. CrossRef
Symptom of vertigo and dizziness in patients with COVID-19
E. V. Isakova
Russian neurological journal.2023; 28(4): 5. CrossRef
Acute vestibular neuritis: A rare complication after the adenoviral vector-based COVID-19 vaccine
Hamze Shahali, Ramin Hamidi Farahani, Parham Hazrati, Ebrahim Hazrati
Journal of NeuroVirology.2022; 28(4-6): 609. CrossRef
A Holistic Approach to a Dizzy Patient: A Practical Update
Ioannis Koukoulithras, Gianna Drousia, Spyridon Kolokotsios, Minas Plexousakis, Alexandra Stamouli, Charis Roussos, Eleana Xanthi
Cureus.2022;[Epub] CrossRef
Identification of hub genes and pathophysiological mechanism related to acute unilateral vestibulopathy by integrated bioinformatics analysis
Yajing Cheng, Jianrong Zheng, Ying Zhan, Cong Liu, Bihua Lu, Jun Hu
Frontiers in Neurology.2022;[Epub] CrossRef

Advances in management of pediatric chronic immune thrombocytopenia: a narrative review: Jae Min Lee; J Yeungnam Med Sci. 2023;40(3):241-246. Published online January 9, 2023; DOI: https://doi.org/10.12701/jyms.2022.00745

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Immune thrombocytopenia (ITP) is a disease in which thrombocytopenia occurs because of immune-mediated platelet destruction and decreased platelet production. Although many pediatric patients with ITP experience spontaneous remission or reach remission within 12 months of first-line therapy, approximately 20% progress to chronic ITP. Patients who do not respond to first-line treatment or experience frequent relapses are of great concern to physicians. This review summarizes recent treatments for second-line treatment of pediatric chronic ITP.

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Beta-Thalassemia with Initial Presentation as Immune Thrombocytopenia: A Case Report
Hyun Sik Kang
Clinical Pediatric Hematology-Oncology.2023; 30(1): 42. CrossRef

Hepatic encephalopathy on magnetic resonance imaging and its uncertain differential diagnoses: a narrative review: Chun Geun Lim, Myong Hun Hahm, Hui Joong Lee; J Yeungnam Med Sci. 2023;40(2):136-145. Published online January 10, 2023; DOI: https://doi.org/10.12701/jyms.2022.00689

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Hepatic encephalopathy (HE) is a severe neuropsychiatric abnormality in patients with either acute or chronic liver failure. Typical brain magnetic resonance imaging findings of HE are bilateral basal ganglia high signal intensities due to manganese deposition in chronic liver disease and hyperintensity in T2, fluid-attenuated inversion recovery, or diffusion-weighted imaging (DWI) with hemispheric white matter changes including the corticospinal tract. Low values on apparent diffusion coefficient mapping of the affected area on DWI, indicating cytotoxic edema, can be observed in acute HE. However, neuropsychological impairment in HE ranges from mild deficits in psychomotor abilities affecting quality of life to stupor or coma with higher grades of hepatic dysfunction. In particular, the long-lasting compensatory mechanisms for the altered metabolism in chronic liver disease make HE imaging results variable. Therefore, the clinical relevance of imaging findings is uncertain and differentiating HE from other metabolic diseases can be difficult. The recent introduction of concepts such as “acute-on-chronic liver failure (ACLF),” a new clinical entity, has led to a change in the clinical view of HE. Accordingly, there is a need to establish a corresponding concept in the field of neuroimaging diagnosis. Herein, we review HE from a historical and etiological perspective to increase understanding of brain imaging and help establish an imaging approach for advanced new concepts such as ACLF. The purpose of this manuscript is to provide an understanding of HE by reviewing neuroimaging findings based on pathological and clinical concepts of HE, thereby assisting in neuroimaging interpretation.

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Citations to this article as recorded by

Rule out all differential causes before attributing cerebral bleeding to 5-aminolevulinic acid
Josef Finsterer, Sounira Mehri
Child's Nervous System.2023; 39(4): 847. CrossRef
Minimal hepatic encephalopathy: clinical, neurophysiological, neuroimaging markers
P. I. Kuznetsova, A. A. Raskurazhev, S. N. Morozova, I. M. Lovchev, M. S. Novruzbekov, M. M. Tanashyan
Russian neurological journal.2023; 28(5): 21. CrossRef

The use of animal models in rheumatoid arthritis research: Jin-Sun Kong, Gi Heon Jeong, Seung-Ah Yoo; J Yeungnam Med Sci. 2023;40(1):23-29. Published online November 22, 2022; DOI: https://doi.org/10.12701/jyms.2022.00773

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Abstract PDF: The pathological hallmark of rheumatoid arthritis (RA) is a synovial pannus that comprises proliferating and invasive fibroblast-like synoviocytes, infiltrating inflammatory cells, and an associated neoangiogenic response. Animal models have been established to study these pathological features of human RA. Spontaneous and induced animal models of RA primarily reflect inflammatory aspects of the disease. Among various induced animal models, collagen-induced arthritis (CIA) and collagen antibody-induced arthritis (CAIA) models are widely used to study the pathogenesis of RA. Improved transplantation techniques for severe combined immunodeficiency (SCID) mouse models of RA can be used to evaluate the effectiveness of potential therapeutics in human tissues and cells. This review provides basic information on various animal models of RA, including CIA and CAIA. In addition, we describe a SCID mouse coimplantation model that can measure the long-distance migration of human RA synoviocytes and cartilage destruction induced by these cells.

Classification of endometriosis: Soo-Young Lee, Yu-Jin Koo, Dae-Hyung Lee; Yeungnam Univ J Med. 2021;38(1):10-18. Published online August 7, 2020; DOI: https://doi.org/10.12701/yujm.2020.00444

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40 Citations

Abstract PDF

Endometriosis is a chronic disease associated with pelvic pain and infertility. Several classification systems for the severity of endometriosis have been proposed. Of these, the revised American Society for Reproductive Medicine classification is the most well-known. The ENZIAN classification was developed to classify deep infiltrating endometriosis and focused on the retroperitoneal structures. The endometriosis fertility index was developed to predict the fertility outcomes in patients who underwent surgery for endometriosis. Finally, the American Association of Gynecological Laparoscopists classification is currently being developed, for which 30 endometriosis experts are analyzing and researching data by assigning scores to categories considered important; however, it has not yet been fully validated and published. Currently, none of the classification systems are considered the gold standard. In this article, we review the classification systems, identify their pros and cons, and discuss what improvements need to be made to each system in the future.

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Ultrasound Characteristics and Scanning Techniques of Uterosacral Ligaments for the Diagnosis of Endometriosis
Shae Maple, K Jane Chalmers, Eva Bezak, Katelyn Henry, Nayana Parange
Journal of Ultrasound in Medicine.2023; 42(6): 1193. CrossRef
The Influence of Lactoferrin in Plasma and Peritoneal Fluid on Iron Metabolism in Women with Endometriosis
Ewa Skarżyńska, Monika Wróbel, Hanna Zborowska, Mateusz Franciszek Kołek, Grzegorz Mańka, Mariusz Kiecka, Michał Lipa, Damian Warzecha, Robert Spaczyński, Piotr Piekarski, Beata Banaszewska, Artur Jakimiuk, Tadeusz Issat, Wojciech Rokita, Jakub Młodawski,
International Journal of Molecular Sciences.2023; 24(2): 1619. CrossRef
Long Non-Coding RNA SNHG4 Expression in Women with Endometriosis: A Pilot Study
Tomasz Szaflik, Hanna Romanowicz, Krzysztof Szyłło, Beata Smolarz
Genes.2023; 14(1): 152. CrossRef
Epidemiological and Immune Profile Analysis of Italian Subjects with Endometriosis and Multiple Sclerosis
Brunella Zizolfi, Virginia Foreste, Simona Bonavita, Valentina Rubino, Giuseppina Ruggiero, Vincenzo Brescia Morra, Roberta Lanzillo, Antonio Carotenuto, Francesca Boscia, Maurizio Taglialatela, Maurizio Guida
Journal of Clinical Medicine.2023; 12(5): 2043. CrossRef
Rectal endometriosis imaging: A case based pictorial essay
Garvit D. Khatri, Deepashri Basavalingu, Nitin Chaubal, Manjiri Dighe
WFUMB Ultrasound Open.2023; 1(1): 100002. CrossRef
KRAS mutations and endometriosis burden of disease
Natasha L Orr, Arianne Albert, Yang Doris Liu, Amy Lum, JooYoon Hong, Catalina L Ionescu, Janine Senz, Tayyebeh M Nazeran, Anna F Lee, Heather Noga, Kate Lawrenson, Catherine Allaire, Christina Williams, Mohamed A Bedaiwy, Michael S Anglesio, Paul J Yong
The Journal of Pathology: Clinical Research.2023; 9(4): 302. CrossRef
The Clinical Presentation of Endometriosis and Its Association to Current Surgical Staging
Matilda Shaked Ashkenazi, Ole Linvåg Huseby, Gard Kroken, Marcela Trocha, Aurora Henriksson, Hanna Jasiak, Karen Cuartas, Alessandra Loschiavo, Isabella Kuhn, Dina Støve, Hanna Grindahl, Emilia Latour, Mathias Melbø, Katrine Holstad, Sebastian Kwiatkowski
Journal of Clinical Medicine.2023; 12(7): 2688. CrossRef
Evaluation and management of endometriosis
T. Yoldemir
Climacteric.2023; 26(3): 248. CrossRef
COX isozymes and non-uniform neoangiogenesis: What is their role in endometriosis?
Andrea Caruana, Charles Savona-Ventura, Jean Calleja-Agius
Prostaglandins & Other Lipid Mediators.2023; 167: 106734. CrossRef
Time to move beyond surgical classification systems for endometriosis
María Isabel Hernández Cardona, Christana Ajewole, Hannah Lewis, Jorge F. Carrillo, Mario E. Castellanos, Stefanie Barish, Juan Diego Villegas Echeverri, Georgine Lamvu
International Journal of Gynecology & Obstetrics.2023; 163(1): 58. CrossRef
Antimüllerian hormone (AMH) and age as predictors of preimplantation genetic testing for aneuploidies (PGT-A) cycle outcomes and blastocyst quality on day 5 in women undergoing in vitro fertilization (IVF)
A. Arnanz, A. Bayram, I. Elkhatib, A. Abdala, A. El-Damen, R. Patel, B. Lawrenz, L. Melado, H. Fatemi, N. De Munck
Journal of Assisted Reproduction and Genetics.2023; 40(6): 1467. CrossRef
Association between polymorphisms of cytokine genes and endometriosis: A comprehensive systematic review and meta-analysis
Shulin Zhong, Yuzhen Liang, Zhixi Wu, Li Wei
Journal of Reproductive Immunology.2023; 158: 103969. CrossRef
Psychological hallmarks of endometriosis with emphasis on sexual dysfunction, stress, anxiety and depressive symptoms
Ludek Fiala, Jiri Lenz, Zdenek Adamik, Rachel Sajdlova, Daniela Kestlerova, Vaclav Vetvicka
International Clinical Pathology Journal.2023; 10(1): 45. CrossRef
Detection of Endometriosis Lesions Using Gd-Based Collagen I Targeting Probe in Murine Models of Endometriosis
Nazanin Talebloo, Maria Ariadna Ochoa Bernal, Elizabeth Kenyon, Christiane L. Mallett, Asgerally Fazleabas, Anna Moore
Molecular Imaging and Biology.2023; 25(5): 833. CrossRef
Exosomal microRNAs and long noncoding RNAs: as novel biomarkers for endometriosis
Elahe Soltani-Fard, Marzieh Asadi, Sina Taghvimi, Asma Vafadar, Parisa Vosough, Amir Tajbakhsh, Amir Savardashtaki
Cell and Tissue Research.2023; 394(1): 55. CrossRef
Use of the Free Endometriosis Risk Advisor App as a Non-Invasive Screening Test for Endometriosis in Patients with Chronic Pelvic Pain and/or Unexplained Infertility
Camran Nezhat, Ellie Armani, Hsuan-Chih Carolina Chen, Zahra Najmi, Steven R. Lindheim, Ceana Nezhat
Journal of Clinical Medicine.2023; 12(16): 5234. CrossRef
Endometriosis: Classification, pathophysiology, and treatment options
Elma Pašalić, Murtaza M. Tambuwala, Altijana Hromić-Jahjefendić
Pathology - Research and Practice.2023; 251: 154847. CrossRef
Endometriosis Grade 4 in In Vitro Fertilisation and Its Management: A Case Report
Abhijeet Raj, Kshiti P Deshpande, Neema Acharya
Cureus.2023;[Epub] CrossRef
Imaging of Urinary Bladder and Ureteral Endometriosis with Emphasis on Diagnosis and Technique
Anuradha S. Shenoy-Bhangle, Izabela Pires Franco, Lauren J. Ray, Jinjin Cao, Aoife Kilcoyne, Natally Horvat, Luciana Pardini Chamie
Academic Radiology.2023;[Epub] CrossRef
Comparison of Clinical and Reproductive Outcomes between Adenomyomectomy and Myomectomy
Kristyna Hlinecka, Michal Mara, Barbora Boudova, Zdenka Lisa, Adela Richtarova, David Kuzel
Journal of Minimally Invasive Gynecology.2022; 29(3): 392. CrossRef
Evaluating Surgical Complexity of Endoscopic Hysterectomy: An Inter-rater and Intra-rater Agreement Study of Novel Scoring Tool
Meenal Misal, Marlene Girardo, Sadikah Behbehani, Vimee Bindra, Mark R. Hoffman, Wei How Lim, Courtney Martin, Sukrant K. Mehta, Alysha Nensi, Thiers Soares, Deborah Taylor, Steve Wagner, Kelly N. Wright, Megan N. Wasson
Journal of Minimally Invasive Gynecology.2022; 29(5): 683. CrossRef
MRI in the Diagnosis of Endometriosis and Related Diseases
Aki Kido, Yuki Himoto, Yusaku Moribata, Yasuhisa Kurata, Yuji Nakamoto
Korean Journal of Radiology.2022; 23(4): 426. CrossRef
Role of Robotic Surgery in Benign Gynecology
Mireille D. Truong, Lauren N. Tholemeier
Obstetrics and Gynecology Clinics of North America.2022; 49(2): 273. CrossRef
NLRP3 activated macrophages promote endometrial stromal cells migration in endometriosis
Feng Zhou, Fanxuan Zhao, Qianmeng Huang, Xiang Lin, Songying Zhang, Yongdong Dai
Journal of Reproductive Immunology.2022; 152: 103649. CrossRef
Endometriosis: A Disease with Few Direct Treatment Options
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Hypertension and cognitive dysfunction: a narrative review: Eun-Jin Cheon; J Yeungnam Med Sci. 2023;40(3):225-232. Published online November 29, 2022; DOI: https://doi.org/10.12701/jyms.2022.00605

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Cognitive dysfunction is relatively less considered a complication of hypertension. However, there is sufficient evidence to show that high blood pressure in middle age increases the risk of cognitive decline and dementia in old age. The greatest impact on cognitive function in those with hypertension is on executive or frontal lobe function, similar to the area most damaged in vascular dementia. Possible cognitive disorders associated with hypertension are vascular dementia, Alzheimer disease, and Lewy body dementia, listed in decreasing strength of association. The pathophysiology of cognitive dysfunction in individuals with hypertension includes brain atrophy, microinfarcts, microbleeds, neuronal loss, white matter lesions, network disruption, neurovascular unit damage, reduced cerebral blood flow, blood-brain barrier damage, enlarged perivascular damage, and proteinopathy. Antihypertensive drugs may reduce the risk of cognitive decline and dementia. Given the high prevalence of dementia and its impact on quality of life, treatment of hypertension to reduce cognitive decline may be a clinically relevant intervention.

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Resident fellow section: Clinical vignette

Differential diagnosis for unusually dilated coronary sinus and right coronary artery incidentally found on echocardiography: Byeng-Ju Son, Hojeong Kim, Jong-Ho Nam; J Yeungnam Med Sci. 2023;40(4):461-465. Published online October 6, 2023; DOI: https://doi.org/10.12701/jyms.2023.00906

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