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Sei One Shin 27 Articles
Electromagnetic Fields in General Hospital.
Sei One Shin, Sang Mo Yun, Hyoun Jin Shin, Hyun Soo Ahn, Hee Deok Ahn
Yeungnam Univ J Med. 2004;21(2):167-176.   Published online December 31, 2004
DOI: https://doi.org/10.12701/yujm.2004.21.2.167
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BACKGROUND
Electromagnetic fields (EMF) are ubiquitous in modern society including medical field. As the technology of medical instruments and telecommunications has developed rapidly, it has influenced on our lives in many ways. Modern medical practice requires high quality medical equipments, which have a great deal of electromagnetic interference and susceptibility. The purpose of this study were to evaluate electromagnetic condition under usual clinical condition and to suggest a practical guideline in general hospital. MATERIALS AND METHODS: The actual state of the electromagnetic interference in the medical field was studied under usual clinical conditions including operating rooms, intensive care units, magnetic resonance imaging unit, and hyperthermia unit. RESULTS: There was considerable noise as a result of electromagnetic fields from medical equipments including electrosurgical units and hyperthermia unit, and cellular phones, which could induce serious functional derangements of functioning medical devices. CONCLUSION: It will be necessary to evaluate the individual electromagnetic situations under various medical conditions and to define a limited zone for cellular phone as well as reposition medical equipments to secure a safer medical practice and to minimize electromagnetic interference.
Evaluation of Treatment Response Using Diffusion-Weighted MRI in Metastatic Spines.
Jang Jin Lee, Sei One Shin
Yeungnam Univ J Med. 2001;18(1):30-38.   Published online June 30, 2001
DOI: https://doi.org/10.12701/yujm.2001.18.1.30
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BACKGROUND
The purpose of this study was to evaluated the usefulness of diffusion-weighted magnatic resonance imaging for monitoring the response to radiation therapy in metastatic bone marrow of the spines. MATERIALS AND METHOD: Twenty-one patients with metastatic bone marrow of the spine were examined with MRI. Diffusion-weighted and spin-echo MRI were performed in 10 patients before and after radiation therapy with or without systematic chemotherapy, and performed in 11 patiemts after radiation therapy alone. Follow up spin-echo and diffusion-weighted MRI were obtained at 1 to 6 months after radiation therapy according to patients' condition. The diffusion-weighted imaging sequence was based on reversed fast imaging with steady-state precession(PSIF). Signal intensity changes of the metastatic bone marrows before and after radiation therapy on conventional spin-echo sequence MRI and diffusion-weighted MRI were evaluated. Bone marrow contrast ratios and signal-to-noise ratio before and after radiation therapy of diffusion-weighted MRI were analyzed. RESULTS: All metastatic bone marrow of the spinal bodies were hyperintense to normal bone marrow of the spinal bodies on pretreatment diffusion-weighted MRI and positive bone marrow contrast ratio(p<0.001). and hypointense to normal spinal bodies on posttreatment diffusion-weighted MRI and negative bone marrow contrast ratio(p<0.001). The signal to noise ratio after treatment decreased comparing with those of pretreatment. Decreased signal intensity of the metastatic bone marrows on diffusion-weighted MRI began to be observed at average more than one month after the initiation of the radiation therapy. CONCLUSION: tThese results suggest that diffusion-weighted MRI would be an excellent method for monitoring the response to therapy of metastatic bone marrow of the spinal bodies. However, must be investigated in a larger series of patients with longer follow up period.
Design of a New Applicator for High-Dose Rate Vaginal Brachytherapy.
Sei One Shin
Yeungnam Univ J Med. 2000;17(2):123-128.   Published online December 31, 2000
DOI: https://doi.org/10.12701/yujm.2000.17.2.123
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PURPOSE: This study was aimed to develop a new vaginal applicator(Shin's Applicator) for 2-channel high-dose rate vaginal brachytherapy to evaluate uniformity of surface dose, and to present 3-dimensional dose distribution of the applicator. METHODS: Shin's Applicator was inexpensively constructed using human soft tissue equivalent acrylic bar. We evaluated dose uniformity along the applicator surface using film densitometer and performed vaginal intracavitary brachytherapy after insertion of the applicator using HDR brachytherapy planning software and brachytherapy unit(Ralstron-20B). RESULTS: Shin's Applicator allows improved dose distribution than the existing 1-channel cylinder and achieves diminished urinary bladder and rectal dose by 20%. CONCLUSIONS: From the above results, it can be concluded that Shin's Applicator may be an improved form of a vaginal applicator. Furthermore, it can be suggested that this applicator has an advantage, for it prevents vaginal stenosis after radiation therapy and can be used as a disposable vaginal dilator. Further follow up examination with radiological study may be helpful to evaluate the therapeutic efficacy of this applicator.
Development of Multichannel On-line Thermometry System.
Sei One Shin, Hyun Jin Shin, Myung Se Kim, Sung Kyu Kim
Yeungnam Univ J Med. 1999;16(2):193-199.   Published online December 31, 1999
DOI: https://doi.org/10.12701/yujm.1999.16.2.193
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BACKGROUND
Measurement of body temperature is an important parameter inpatient management in many clinical condition. Failure to reach minimal acceptable and has necessitated the application of additional therapy. The authors developed a new, simple, accurate thermometry system, which could be used to undertake precise temperature measurement for various clinical conditions. MATERIALS AND METHODS: A new thermometry system using a specially designed temperature detecting and display system was developed. This system contains a temperature detecting sensor(LM 35CZ), which enables multiple serual checking of heat, data collection and processing computer, and 3-dimensional display system. It provides realtime volumetric visualization of temperature of a defined volume and stores and prints the data. RESULTS: With this system, temperature can be measured at multiple interesting sites simultaneously , demonstrated as a 3-dimensional temperature distribution and stored. In well-controlled, systematic experiments a significant correlation has been observed between standard temperature using this system at carious measuring points. CONCLUSION: This thermonetry system is a real-time measurement system, which can demonstrate 3-dimensional heat distribution in experimental phantom and human body and can be used for diagnosing abnormal conditions. In addition, this system reduces the nursing staff work load, providing them more time for long term care to patients.
Sequential Combination Chemotherapy and Radiotherapy of an Isolated Non-Hodgkin's Lymphoma of the Larynx: Report of A Case.
Sei One Shin, Myung Se Kim, Sung Kyu Kim, Young Ran Shim
Yeungnam Univ J Med. 1997;14(2):443-450.   Published online December 31, 1997
DOI: https://doi.org/10.12701/yujm.1997.14.2.443
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  • Individual participant data meta-analysis of primary laryngeal lymphoma: Focusing on the clinical characteristics and prognosis
    Kyung Hee Kim, Rock Bum Kim, Seung Hoon Woo
    The Laryngoscope.2015; 125(12): 2741.     CrossRef
Computerzation of Radiation Oncology Practice Using Order-Communicating System.
Sei One Shin, Ji Won Yei
Yeungnam Univ J Med. 1996;13(1):97-109.   Published online June 30, 1996
DOI: https://doi.org/10.12701/yujm.1996.13.1.97
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Recently there has been attempts to develop hospital information system including order communicating system, patient tracing system, tumor registry system, office automation system and picture archiving and communication system(PACS). The authors devloped a practical system that was operated via order communication system of Yeungnam University Hospital. The system provided us the 'speed, accuracy, reliability, retention, economy and wide applicability through practical test. So we believed that this system would be one of standard computerized programs in radiation oncology practice and providing widely usable data for clinical statistics, medical record, tumor registry system and clinical researches.
Therapeutic Results of Radiotherapy in Nonsmall Cell Lung Cancers.
Sei One Shin, Sung Kyu Kim, Myung Se Kim
Yeungnam Univ J Med. 1994;11(1):72-81.   Published online June 30, 1994
DOI: https://doi.org/10.12701/yujm.1994.11.1.72
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Total 55 patients with nonsmall cell lung cancer treated with radiation therapy at Department of Therapeutic Radiology, Yeungnam University Hospital, between May-1 1986 and April-30 1993 were retrospectively analyzed by clinical characteristics, failure patterns follow up duration and survival ratio according to prognostic factors. Obtained results were as follows : 1. Male to female ratio was 17.3 2. Sixth and seventh decades were predominant age group. 3. The patients were 8 in stage I-II, 34 in stage IIIA, 13 in stage IIIb, respectively. 4. Forty five patients out of 55 were squamous cell carcinoma. 5. Primary tumor were originated from upper lobe bronchi predominantly. 6. The size of the primary tumor, lymph node involvement and the degree of differentiation were important in evaluation of prognosis. 7. In conclusion, for patients with poor prognostic factors systemic chemotherapy and multidisciplinary approach were recommended for better treatment outcome and improvement of survival.
Conservative surgery and definitive radiotherapy in early breast cancer
Sei One Shin, Jung Sook Hong, Myung Se Kim, Young Do Lee, Sung Kyu Kim, Soo Jung Lee
Yeungnam Univ J Med. 1993;10(2):380-387.   Published online December 31, 1993
DOI: https://doi.org/10.12701/yujm.1993.10.2.380
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Local excision and axillary dissection followed by radiation therapy to the breast has been shown to achieve equivalent local control and survival as mastectomy in an prospective randomized trials. We analyzed 28 cases of early breast cancer in order to evaluate the therapeutic effects of conservative f surgery and definitive radiotherapy in the management of early breast cancer as possible alternative of simple mastectomy, retrospectively. Obtained results were as follows 1. Treatment related acute side reactions are more prominant in the case of chemoradiotherapy group than radiotherapy alone group. 2. There were no cases of primary, regional or systemic failures on the last follow up examination. 3. Cosmetic results after treatment were satisfactory in 26 cases out of 28 cases on the last follow up examination. 4. There were no demonstrable differences of tumor control and cosmetic results between the treatment groups. Although, these results suggested that definitive radiotherapy after local excision would be a possible and desirable alternative instead of total mastectomy in the management of early breast cancers, analyzed cases were too small and follow up period was too short to evaluate the therapeutic effect of primary radiotherapy after local excision, exactly.
Radition effect on colony formation of hela.S3(SC) cell line.
Sei One Shin, Sung Kyu Kim, Myung Se Kim
Yeungnam Univ J Med. 1993;10(1):212-217.   Published online June 30, 1993
DOI: https://doi.org/10.12701/yujm.1993.10.1.212
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Since discovery of X-rays, radiotherapy has evolved into one of the most scientific branches of medicine and has established its role as the primary line or the secondary line of attack, after surgery,. in the treatment of malignant cancers. Nowadays its importance is illustrated by the fact that as many as 70 per cent of all pastients with cancer will receive radiation therapy at sometime during their disease process. Biologic effects-of X-rays began to be apparant soon after the discovery by Roentgen in 1895. In clinical radiotherapy, the biologic endpoint of most importance is loss of cellular reproductive ability or clonogenicity. One of the commonest ;nays to assess cell survival is to use an in vitro plating assay. We analyzed radiation effect on colony formation of HaLa. S3(SC) cell line and obtained results are as follows The plating efficiency is 0.464. The shape of cell survival curve is similar to multi-target plus single hit component model. Estimated values of Do, Dq, and extrapolation number are 150 cGy, 80 cGy and 1.7 respectively. We reported these experimental data with review of literature.
Radiation therapy of nasopharyngeal cancers.
Sei One Shin, Sung Kyu Kim, Myung Se Kim
Yeungnam Univ J Med. 1992;9(2):312-320.   Published online December 31, 1992
DOI: https://doi.org/10.12701/yujm.1992.9.2.312
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Radiotherapeutically, nasopharyngeal caner is an important disease in Korea. Because of its blind anatomic location, early detection is relatively uncommon. Clinically, most of cases are locally advanced and nodal involvements are common. Recently better understanding of nature of the disease and improvement of radio – therapy technique permit better treatment result, including locoregional control and survival rate, and minimal normal tissue damages comparing with previously published date. We analyzed 31 patients of pathologically proven and previously untreated naso – pharyngeal carcinoma with different treatment techniques, retrospectively. Minimal and maximal follow up period of the survivor is 6 months and 68 months, respectively. Thirteen patients with squamous cell carcinoma are included in this analysis. The median age is 49 years (range from 20 to 64 years). Twenty two patients are stage III. Eleven patients are treated with radiotherapy alone and 20 are treated with combined modalities treatment. The degree of response after radiotherapy are categorized by 3-classes, i,e. complete response, partial response. In spite of similarities of complete response rate and 1-year survival rate between two different treatment techniques, those patients with undifferentiated carcinoma appear to benefit from the adjuvant chemotherapy. In addition, systemic failure is more suggest that adjuvant therapy in the radiotherapeutic management of nasopharyngeal cancer needs additional research according to histologic types and future extensive clinical trials.
Palliative effect of radiation therapy in management of symptomatic osseous metastases
Sei One Shin, Sung Kyu Kim, Myung Se Kim
Yeungnam Univ J Med. 1992;9(1):102-109.   Published online June 30, 1992
DOI: https://doi.org/10.12701/yujm.1992.9.1.102
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Bone metastases represent an important and frequent clinical problem in patients with advanced cancers. Especially, painful bone metastases are common features in these patients. Radiotherapy is an effective tool for palliative aim of painful metastatic osseous lesions. Various treatment results have been previously reported. The present retrospective study was aimed to evaluate the efficacy of palliative irradiation on pain relief, with the goal of selecting appropriate irradiation dose schedule. Radiotherapy consisted of 5 times a week with a various fractional dose between 180 and 400cGy. The response of pain relief and the survival time after completion of radiotherapy are related to total dose and most of the patients have shown a similar response by the end of radiotherapy. The higher dose and the more aggressive multimodality treatment, the better pain control and the longer survival time.
A study on dose distribution of small irradiation field in the electron therapy.
Sung Kyu Kim, Sei One Shin, Myung Se Kim
Yeungnam Univ J Med. 1991;8(2):114-120.   Published online December 31, 1991
DOI: https://doi.org/10.12701/yujm.1991.8.2.114
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In electron therapy, low melting point alloy is used for shaping of the field. Electron field shaping material affect the output factor as well as the collimator system. The output factors of electron beams for shaped fields from NELAC-1018 were measured using ionization chamber of Farmer type in water phantom. The output factors of electron beams depend on the incident energy, inherent collimator system and the size of shaped field. Obtained results were followings. 1. In the smaller applicator, output varied extremely according to extent of collimator opening. 2. The higher energy, the output is less varied according to treatment field at small field.
A study of dose distribution in postoperative radiotherapy in uterine cervical cancer.
Sei One Shin, Sung Kyu Kim, Myung Se Kim
Yeungnam Univ J Med. 1991;8(1):166-177.   Published online June 30, 1991
DOI: https://doi.org/10.12701/yujm.1991.8.1.166
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Uterine cervical cancer is the most common malignancy in Korean women. In spite of recent development of early diagnostic and therapeutic modalities, about 40% of treated patient will develop relapse. So more aggressive local treatment such as more extensive surgery and higher radiation dose and administration of systemic chemotherapy will promote the curability but treatment related complications cannot be avoidable. We used 22 cases of early cervical cancer, treated with surgery and post-operative radiotherapy, clinical data of these patients were analyzed to determine relationship between clinical parameters and final outcome. Three out of 22 cases revealed relapse and one patient showed rectovaginal fistula and another patient showed small bowel obstruction and the other patient showed rectal obstruction. Two out of three recurrence were stage IIa and the other one case was stage Ib adenocarcinoma with lymphovascular involvement. Nineteen out of 22 cases were followed without remarkable side effect or treatment related complication or sequelae. We concluded that out treatment policy was safe and effective to eradicate high risk postoperative cervical cancer with acceptable side effects or complication.
The Clinical Review of Superior Vena Cava Syndrome.
Joung Sun Kang, Sam Beom Lee, Choong Ki Lee, Jin Hong Chung, Hyoung Woo Lee, Kwan Ho Lee, Myung Soo Hyun, Hyun Woo Lee, Sei One Shin, Myung Se Kim
Yeungnam Univ J Med. 1990;7(2):151-158.   Published online December 31, 1990
DOI: https://doi.org/10.12701/yujm.1990.7.2.151
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We reviewed 30 cases of superior vena cava syndrome in adult patients who were seen at the Yeungnam University Hospital from January 1985 to June 1990. The results were as follows: 1. The male-to-female ratio was 6.5:1, and the most patients were in the age group between the sixth and seventh decades. 2. The most common symptoms were dyspnea (87%) and followed by cough (63%), facial swelling (63%) and chest pain (44%) and the physical signs were dilated neck vein (97%), facial edema (93%) and facial flushing (45%) in order of frequency. 3. The simple chest x-ray findings were superior mediastinal widening (90%), right hilar mass (77%) and pleural effusion (31%). 4. Diagnosis was made by history and physical examination (100%), chest C-T scan (100%), simple chest x-ray (97%), bronchoscopy with biopsy (40%) and so on. 5. 21 cases of patients were confirmed by histology: 14 cases (46%) of bronchogenic ca, 4 cases (14%) of lymphoma, 3 cases (10%) of metastatic lung ca. Of bronchogenic ca, small cell ca was 7 cases (23%), squamous cell ca, 5 cases (17%), and unclassified cawas 2 cases (6%). 6. In response of treatment, the clinical improvement was achieved in 18 cases with radiotherapy alone, 1 case with chemotherapy only, and 6 cases with radio-chemotherapy.
A Study on the dosimetry in boundary of shielding block in high energy irradiation.
Myung Se Kim, Sung Kyu Kim, Sei One Shin
Yeungnam Univ J Med. 1990;7(2):115-120.   Published online December 31, 1990
DOI: https://doi.org/10.12701/yujm.1990.7.2.115
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Scatter-air ratios are used for the purpose of calculating scattered dose in the medium. The computation of the primary and the scattered dose separately is particularly useful in the dosimetry of irregular fields with shielding block in radiation field, dose distribution of scattered radiation using 18MeV Linear accelerator and Co-60 teletherapy measured. The effect of scattered radiation dose by protecting block was been ignored in radiation therapy, 2-3% of scattered radiation may be 90-200cGy which could be influence vital complication such as cataract, oligospermia or sterility. So that exact calculate scattered radiation by protecting block exactly for irregular field c small protection of vital organ is very important. The purpose of this article is to calculate scattered radiation by protecting block exactly for irregular field c Linac or Co-60 irradiation and to applicate these data in clinical radiation field. Authors could obtain following results. 1. The lesser angle between shielding block showed more scattered radiation. 2. With decreasing distance between shielding blocks, the dependent of scattered radiation were increased. 3. Output of 18 MeV Linear accelerator and Co-60 was related linear proportion on field size, but independent according to the size of shielding block in 18 MeV Linear accelerator.
Radiation Therapy of Head and Neck Cancer with CO-6O HDR Transcatheteric Irradiation.
Sei One Shin, Sung Kyu Kim, Myung Se Kim
Yeungnam Univ J Med. 1990;7(2):109-114.   Published online December 31, 1990
DOI: https://doi.org/10.12701/yujm.1990.7.2.109
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The basic strategy of irradiation is to deliver a dose to the cancer that is high enough to make cancer cells incapable of reproduction, while keeping the doses to the various healthy tissues below tolerable levels. In order to improve local control and survival, as a boost therapy after external radiotherapy, high dose rate transcatheteric irradiation using remote control after loading system (RALSTRON-20B) was used for twelve patients with head and neck cancers. Present results showed complete remission of cancer in 9 out of 112 patients without treatment related complications. Although this procedure is easy to operate, well trained skillful hand in essential for good results. Furthermore out experience suggested that meticulous treatment planning should be developed for better results.
Two Cases of Nasopharyngeal Carcinoma Treated with Co-60 HDR ICR.
Sei One Shin, Cheol Hoon Kang, Seong Gyu Kim, Myung Se Kim
Yeungnam Univ J Med. 1990;7(1):197-201.   Published online June 30, 1990
DOI: https://doi.org/10.12701/yujm.1990.7.1.197
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AbstractAbstract PDF
The primary treatment modality of malignant tumors of the nasopharynx is radiation therapy owing to its inaccessibility to surgical intervention. Over the last two decades there were many changes in techniques of delivery, which include the use of higher doses of radiotherapy, the use of wide radiation field, including the elective radiation of the whole neck, the combined use of brachy- and teletherapy, and the use of split-course therapy. In spite of these advances local and regional recurrences remain the major cause of death. As a boost therapy after external irradiation, high-dose-rate intracavitary irradiation using remote control afterloading system (RALS) was used in two patients. Our results were satisfactory, however, this procedure should only be performed by those who have developed enough expertise in the use of intracavitary techniques for the treatment of nasopharyngeal cancer and have a supportive team including a physicist, dosimetrist, nurse, and trained technologist.
The Dosimetry of Radiosurgery using of Rando Phantom.
Sung Kyu Kim, Sei One Shin, Myung Se Kim
Yeungnam Univ J Med. 1990;7(1):113-119.   Published online June 30, 1990
DOI: https://doi.org/10.12701/yujm.1990.7.1.113
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AbstractAbstract PDF
The stereotactic radiosurgery using ionizing radiation of high energy is a technique for exadicating intracranial small tumors, which are inaccessible or unsuitable for open surgical technique. For such a small field radiosurgery, TLD or film dosimetry is essential. The three dimensional dose planning of radiosurgery was performed with dose planning computer system (Therac 2300). The target dose distribution and its error according to patient position were discussed. And were measured of circular cone which specially designed in our Hospital. The position error of Rando Phantom compared with CT were 0.4 mm in the AP-LAT section and in the AP-VERT section, 1.0 mm in the AP-VERT 45°section. The ratio of accuracy of the gantry and couch rotation were 1.5 mm diameter for central axis of 18MeV linear accelerator. Our study suggested that radiosurgery of small field in out department will be appropriate for clinical application.
Radiation Effect on Airway Obstruction from Lung Cancer.
Sei One Shin, Sung Kyu Kim, Myung Se Kim
Yeungnam Univ J Med. 1989;6(2):121-125.   Published online December 31, 1989
DOI: https://doi.org/10.12701/yujm.1989.6.2.121
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AbstractAbstract PDF
Total 21 patients with airway obstruction from lung cancer treated with radiotherapy at Department of Therapeuctic Radiology, Yeungnam University College of Medicine, between April 1986 and December 1988 are retrospectively analyzed by means of roentgenologic findings. Obtained results are as follows. 1. 15 out of 21 patients (71%) showed complete or partial response. 2. Patients with small cell lung cancer showed 100% response in spite of low dose (30 GY/10 fractions.) 3. Patients with non-small cell lung cancer treated with 50 GY or over showed better response than below 45 GY or below. 4. There is no relationship between the response and site of airway obstruction. These date suggested that high dose irradiation is more effective in the management of airway obstruction from lung cancer and meticulous radiotherapy planning with appropriate protection of normal lung and critical organs should be investigated in order to maximize radiation effect and minimize side effect, complication or sequelae.
A Study on the Dose Distribution for Total Body Irradiation using Co-60 Teletherapy Unit.
Sung Kyu Kim, Sei One Shin, Myung Se Kim
Yeungnam Univ J Med. 1989;6(2):113-119.   Published online December 31, 1989
DOI: https://doi.org/10.12701/yujm.1989.6.2.113
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In recent years there has been a growing interest in total body, hemibody, total lymphoid irradiation. For refractory leukemia or lymphoma patients, various techniques and dose regimens were introduced, including high dose total body irradiation for destruction of leukemic or bone marrow cells and immunosuppression prior to bone marrow transplantation, and low dose total body irradiation for treatment of lymphocytic leukemias or lymphomas. Accurate provision for specified dose and the desired homogeneity are essential before clinical total body irradiation. Purposes of this paper are to discuss calibrating Cobalt Unit in 3m distance using Rando Phantom, to compare calculated dose, calibrated dose, and compensating filters for homogeneous dose distribution in the head and neck, the lung and the pelvis. Results were following. 1. Measured dose on the lung was 6% higher than on the abdomen. Measured dose on the head (10%) and neck (18%) were higher than the abdomen because of thinness. Pelvic dose was measured 12% less than the abdomen. Those date suggest that compensating filter was essential. 2. Measured dose according to distance was 3% less than calculated dose which suggest that all doses in clinical use should be compared with calculated dose for minimizing error.
Clinical Evaluation of Dose Distribution in High Dose Rate Intracavitary Irradiation in the Treatment of Cervical Cancer.
Sei One Shin, Myung Se Kim
Yeungnam Univ J Med. 1989;6(1):87-98.   Published online June 30, 1989
DOI: https://doi.org/10.12701/yujm.1989.6.1.87
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AbstractAbstract PDF
Clinical estimation of bladder and rectal doses from high dose rate intracavitary irradiation in carcinoma of the cervix uteri has been initiated on a routine basis in an effort to obtain the optimum radiotherapeutic dose. Simulation films with contrast media are used to image the bladder and rectum, and dose rates are estimated at various interesting points with the aid of treatment planning computer, NEC Therac-2300. Fifty-three patients have been reviewed in order to ascertain the correlation between radiation dose at interesting points in the bladder and rectum and the dose at Point A and B. The dose ratio between doses at Point A and interesting points in an important clinical factor in evaluating the treatment planning. This also serves as documentation of the dose to normal structures within the treatment volume. Authors conclude that obtained data are within acceptable ranges and routine simulation films of the bladder and rectum after administration of contrast media with dose calculations at interesting points provide important information for optimizing radiotherapy planning in the treatment of cervical carcinoma without increased time and effort or patient's discomfort.
A Study on ARC Therapy of 18MeV Linear Accelerator.
Seong Kyu Kim, Sei One Shin, Myung Se Kim
Yeungnam Univ J Med. 1988;5(2):31-36.   Published online December 31, 1988
DOI: https://doi.org/10.12701/yujm.1988.5.2.31
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AbstractAbstract PDF
In recent years there has been a growing interest in all forms of rotational therapy, and many different types of therapy machines designed for this kind of treatment have become available. To the medical radiation physicist, the dosimetry of rotation therapy has presented a number of interesting problems, and much useful work has been published on the basic date of dose distribution and dosage calculation. The setting dose for ARC therapy were obtained by computer calculation and measurement with cylindrical phantom. Authors compared computer calculation with measured value. And in ARC therapy, the region of maximum dose in shifted from the tumor center. The extent of shift was analyzed by isodose distribution for ARC therapy techniques.
Intraoperative Radiation Therapy of locally Advanced Gastric Cancers: Case report.
Kyeung Ae Kim, Seong Kyu Kim, Sei One Shin, Myung Se Kim, Hong Jin Kim, Koing Bo Kwun, Hung Dae Kim
Yeungnam Univ J Med. 1988;5(1):153-158.   Published online June 30, 1988
DOI: https://doi.org/10.12701/yujm.1988.5.1.153
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AbstractAbstract PDF
Stomach cancer is the most popular tumor in Korea but the prognosis following extensive surgery and chemotherapy has not improved for many years. Conventional external radiotherapy also has some limitation, namely, a cancerocidal dose cannot be delivered to tumors because of low radiation tolerance of adjacent critical sensitive organs. In order to overcome these limitations of curative surgery and external radiotherapy, intraoperative radiotherapy was proposed in many centers and the results were excellent. We treated two cases of locally advanced gastric cancers with IORT by using NEC 18 MeV Linear Accelerator after standard subtotal resection of the stomach. After treatment, the patients are in good conditions so far, but in order to evaluate the effectiveness of IORT, a study will be performed on the survival rates between patients treated by IORT and those treated by surgery alone.
One Case of Esophageal Cancer Treated with High Dose Rate ICR.
Kyeung Ae Kim, Sung Kyu Kim, Sei One Shin, Myung Se Kim
Yeungnam Univ J Med. 1988;5(1):147-151.   Published online June 30, 1988
DOI: https://doi.org/10.12701/yujm.1988.5.1.147
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AbstractAbstract PDF
Esophageal cancers are highly malignant neoplasms. Prognosis of esophageal cancer treated by external irradiation alone is rather poor because of local recurrence and distant metastasis. Recently intracavitary irradiation has been used as a boost therapy after external irradiation to obtain better local control. One case of esophageal cancer has been treated by high dose rate remote-controlled after loading unit as boost therapy after external irradiation. The result was excellent in short term follow up esophagogram but esophageal bleeding and esophagotracheal fistula were noted in further follow up examination after inappropriate posttreatment management including insufficient chemotherapy due to poor general condition. We reviewed possible causes of esophageal bleeding and esophagotracheal fistula after external irradiation and high dose rate ICR.
Effects of same TDF Factors on Body Weight of Mice and Peripheral Blood Picture.
Sei One Shin, Seong Gyu Kim, Myung Se Kim
Yeungnam Univ J Med. 1987;4(2):89-96.   Published online December 31, 1987
DOI: https://doi.org/10.12701/yujm.1987.4.2.89
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Using same TDE factors, the authors studied the effects of whole abdominal irradiation on body weight and peripheral blood picture in 30±3 day old mice. Fractions of 100 and 200 cGy were given five times a week to the final TDF factors 17, 33, and 49. Total 80 mice were irradiated with orthovoltage x-ray machine. Our results can be summarized as follows: There were no significant differences by sex. Body weight was progressively decreased by the duration for irradiation, but no remarkable difference by fractional dose. Hemoglobin level showed no remarkable change by fractional dose or TDF factors. Leukopenic changes showed that severity of decrease seems to be more related to TDF factors. There were no significant changes of differential count by TDF factors of total doses.
A Study on Equivalent Square Field in High Energy Photon Beam.
Seong Gyu Kim, Sei One Shin, Myung Se Kim
Yeungnam Univ J Med. 1987;4(2):83-88.   Published online December 31, 1987
DOI: https://doi.org/10.12701/yujm.1987.4.2.83
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AbstractAbstract PDF
An analytic expression for equivalent square fields and a table are derived using the empirical representations obtained from the measured field size dependence of output for square field in a phantom. The expression is applicable to radiation fields that consistent with the following two assumptions imposed on these representations. 1) It is a linear function of the logarithm of the field area. 2) It is approximately the same function for both square and circular field of similar areas. In this paper, the derived tables and BJR table were consulted.
Radiation Effect on Body Weight and Peripheral Blood Picture Induced by Whole-Abdominal X-ray Irradiation with Different Fractionation in Mice.
Sung Heon Lee, Sei One Shin, Myung Se Kim
Yeungnam Univ J Med. 1987;4(1):25-32.   Published online August 31, 1987
DOI: https://doi.org/10.12701/yujm.1987.4.1.25
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AbstractAbstract PDF
The object of this study was to determine the difference of radiation effect in different fractional does and to establish optimal fractionation schedule on the whole-abdominal X-ray irradiation. Total 160 mice were irradiated with 150 KVP, 15 mA orthovoltage x-ray machine and two different fractionation (100 cGy/Fr. and 200 cGy/Fr.) were used. Body weight, hemoglobin and WBC count with differential count were analyzed according to the same amount of total dose, same field size and two different fractionation schedules. The results of this study were summarized s follows: There was no significant difference in body weight and hemoglobin concentration by sex or fractional dose. Leukopenic change was prominent in the 3,000 cGy irradiation group and the proportion of decrease was remarkable in the 200 cGy/Fr. Group than 100 cGy/Fr. Group. Progressive decrease of lymphocyte count and reciprocal increase of neutrophil count were noted as dose increment. The effect of the fractional does on WBC count and proportion of lymphocyte were significant. This suggests that judicious selection of fractional dose may be important in clinical radiotherapeutic practice.

JYMS : Journal of Yeungnam Medical Science