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J Yeungnam Med Sci > Volume 16(1); 1999 > Article
Yeungnam University Journal of Medicine 1999;16(1):108-113.
DOI:    Published online June 30, 1999.
Clear cell sarcoma: 1 case report.
Joon Hyuk Choi, Hae Jeong Choi, Mi Jin Kim, Duk Seop Shin, Kil Ho Cho
1Department of Pathology, College of Medicine, Yeungnam University, Taegu, Korea.
2Department of Orthopedic Surgery, College of Medicine, Yeungnam University, Taegu, Korea.
3Department of Diagnostic Radiology, College of Medicine, Yeungnam University, Taegu, Korea.
Clear cell sarcoma is a rare soft tissue sarcoma that occurs tendons and aponeuroses, usually of the lower extremities in young adult. The exact histogenesis is not definitely established, We experienced a case of 58 year-old female who presented with a 3.2x2.2cm sized mass located in the subcutaneous tissue on the left lower thigh. The mass was well circumscribed and grayish firm. Two small satellite nodules were also seen. Histologically the tumor was composed of round to fusiform cells with clear or pale eosinophilic cytoplasm and separated into compact nests or short fascicles by delicated fibrous septa. The melanin pigments and hemosiderin were seen. Tumor cells showed positive reaction for S-100 protein and HMB-45. The ultrastructural examination showed abundant mitochondria and melanosomes.
Key Words: Clear cell sarcoma, Soft tissue, Melanosome


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