Journal of Yeungnam Medical Science

In Vitro Culture of Endothelial Cell and Smooth Muscle Cell for Studying Vascular Diseases.: Joo Young Kim; Yeungnam Univ J Med. 2010;27(2):91-97. Published online December 31, 2010; DOI: https://doi.org/10.12701/yujm.2010.27.2.91

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Abstract PDF: Endothelial cells play a key role in pathological processes such as cancer cell metastasis, atherosclerosis, and diabetic retinopathy. Vascular smooth muscle cells directly involve in the formation of atheroma in atherosclerosis. Some kinds of the endothelial cells are simply harvested from the umbilical veins, the tunica intima of aortic walls, the retina using various enzymes solutions. Those purely isolated cells provide a powerful tool in vitro studies of the endothelial cell related diseases. In this context, the cultured smooth muscle cells after the isolation from the tunica media of aortic walls are also used for elucidating the pathogenesis of atherosclerosis. Here, I briefly introduce articles that include the isolation of human umbilical vein endothelial cells (HUVEC), aortic endothelial and smooth muscle cells, retinal microvascular endothelial cells (RMEC), as well as the diseases' applications of these cells.

Anterior Mediastinal Tumor.: Jae Kyo Lee; Yeungnam Univ J Med. 2010;27(2):98-104. Published online December 31, 2010; DOI: https://doi.org/10.12701/yujm.2010.27.2.98

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Abstract PDF: Primary anterior mediastinal neoplasms comprise a diverse group of tumors and account for 50% of all mediastinal masses. Thymic epithelial neoplasm are most common and classified into thymoma, invasive thymoma, and thymic carcinoma. Neuroendocrine differentiation of thymic epithelial neoplasm are rare malignancies. Germ cell tumor (GCT) is second most common anterior mediastinal tumor and most of them are mature cystic teratoma. Malignant mediastinal GCT are rare than benign. Primary thoracic lymphoma is rare than thoracic involvement of systemic lymphoma and most common location of primary thoracic lymphoma is anterior mediastinum. The clinical and radiologic appearance of the most common masses are reviewed.

Ultrasonographic and Magnetic Resonance Imaging Findings of Testicular Lymphoma.: Jae Ho Cho; Yeungnam Univ J Med. 2010;27(2):105-112. Published online December 31, 2010; DOI: https://doi.org/10.12701/yujm.2010.27.2.105

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Abstract PDF: PURPOSE: To evaluate the specific radiologic findings of testicular lymphoma which will be able to differentiated from other testicular tumors. MATERIAL AND METHODS: Pathologically confirmed eight cases were included in this study. All eight cases were performed ultrasonography and four cases were performed magnetic resonance image. On ultrasonography, the size, location, shape, margin, internal echogenicity, homogeneity and vascularity were evaluated. On magnetic resonance image, the shape, margin, homogeneity, signal intensity on T1- and T2-weighted images, degree and homogeneity of the contrast enhancement and contrast enhancement change on dynamic enhancement study. RESULTS: The margin of the mass was smooth on 6 of 8 patients. Internal echogenicity of the mass lesion was hypoechoic than normal testicular parenchyme on 7 of 8 patients. Four cases were homogeneous, 3 cases were relatively homogeneous and 1 case was heterogeneous. All 8 cases showed increased vascularity. The mass lesion was iso-signal intensity on T1-weighted image and low-signal intensity on T2-weighted image. All four cases were enhanced homogeneously and mildly than enhancing normal testicular parenchyme. On dynamic enhancement study, the mass lesion is progressively enhanced with time. CONCLUSION: The possibility of testicular lymphoma should be considered when testicular mass was homogeneously hypoechoic and low signal intensity on T2-weighted image in old age patients.

Comparative Study on the Infection Rates of Protected Environment versus Non-Protected Environment in Acute Myeloid Leukemia during Remission Induction Chemotherapy.: Se Hoon Sohn, Ha young Lee, Dong Geun Kim, Sung Woo Park, Myung Jin Kim, Myung Jin Oh, Hye Deok Woo, Hun Mo Ryoo, Sung Hwa Bae, Kyung Hee Lee, Min Kyoung Kim, Myung Soo Hyun; Yeungnam Univ J Med. 2010;27(2):113-121. Published online December 31, 2010; DOI: https://doi.org/10.12701/yujm.2010.27.2.113

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Abstract PDF: BACKGROUND
AND PURPOSE: Patients with acute leukemia experience prolonged periods of neutropenia due to their disease or its treatment. For this reason, they often develop serious infectious complications. Although antibiotic therapy has improved in recent years, the fatality rate from infection remains high. For the control of infection, protected environment was developed. But because of economic issue, most of chemotherapy with acute myeloid leukemia have conducted in non-protected environment. So this study compared the rate of complete remission, days with neutropenia, rate of fever, rate of positive culture, rate of overt infection and use of antibacterial and antifungal agents with patients within non-protected environment and protected environment, retrospectively. Patients with acute myeloid leukemia during first remission induction chemotherapy were eligible for this study. METHODS: Retrospective analysis was conducted between patients in non-protected (25 patients) and protected environment (14 patients) with acute myeloid leukemia during remission induction chemotherapy. RESULTS: Rate of overt infection, rate of fever, rate of positive culture and rate of use of antibiotics were significantly high in patients within non-protected environment compared with patients within protected environment. There were no differences in rate of complete remission and days of neutropenia. CONCLUSIONS: This study suggests protected environment for patients with acute myeloid leukemia during remission induction chemotherapy could reduce rate of overt infection, and rate of use of antibiotics.

Medulla Oblangata Injury Caused by Non-Penetrating Trauma by Chopsticks.: Hyeon Ju Jin, Jae Seong Yu, Yu Kyung Kim, Ho Seok Gang, Se Jin Lee; Yeungnam Univ J Med. 2010;27(2):122-126. Published online December 31, 2010; DOI: https://doi.org/10.12701/yujm.2010.27.2.122

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Abstract PDF

It is common in childhood that children suffer intracavity or head injury, falling down backward, having chopsticks in their mouth. But most of them have paralysis of upper and lower extremity because of secondary damage by penetrating injury of brainstem and spine. We could not find this case which have shown infaction of medulla oblangata on MRI and paralysis by impact only without clear penetrating evidence. So the authors report this case with study of literature because we experience one case that have high signal density in brainstem on MRI, Loss of consciousness, and left hemiplegia without clear penetrating evidence after falling down backward, having chopsticks in her mouth and regard it rare case.

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Undetected Metallic Chopstick Stabbed on Neck Resulting Tinnitus and Foreign Body Sensation
Sun A Choi, Sung Bum Kim, Seung Youp Shin, Young Gyu Eun
Journal of Korean Neurosurgical Society.2015; 57(2): 140. CrossRef

A Case of Acute Renal Failure Associated with Non-fulminant Acute Hepatitis A.: Ji Hoon Na, Jong Won Park, Kyu Hwan Park, Myong Jin Oh, Yun Jung Choi, Jung Min Park, Woo Jin Chang; Yeungnam Univ J Med. 2010;27(2):127-132. Published online December 31, 2010; DOI: https://doi.org/10.12701/yujm.2010.27.2.127

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Abstract PDF: Acute hepatitis A is a generally self-limiting disease of the liver. Acute renal failure is rare in patients with acute non-fulminant hepatitis A. Acute tubular necrosis is the most common form of renal injury found in such patients. The 36 years old male patient visited our hospital with complaint of general weakness, fatigue, nausea, vomiting and myalgia. He was diagnosed with acute renal failure associated with acute non-fulminant hepatitis A. We report here on a case of acute renal failure associated with non-fulminant hepatitis A, and we include a review of the literature.

Apical Hypertrophic Cardiomyopathy with Apical Aneurysm and Thrombus Diagnosed by Contrast Echocardiography.: Kyu Hwan Park, Geu Ru Hong, Jong Ho Nam, Min Kyu Kang, Su Mi Kim, Seong Yoon Jung, Ji Hoon Na; Yeungnam Univ J Med. 2010;27(2):133-138. Published online December 31, 2010; DOI: https://doi.org/10.12701/yujm.2010.27.2.133

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Abstract PDF: Apical hypertrophic cardiomyopathy is rare disease and a variant of hypertrophic cardiomyopathy with prevalence of 1 in 500 in the general population. Apical hypertrophic cardiomyopathy with apical aneurysm and intramural thrombus is extremely rare. We report a case of apical hypertrophic cardiomyopathy progressing to left ventricular apical aneurysm with intramural thrombus diagnosed by contrast echocardiography.

A Case of Functionary Cystic Parathyroid Adenoma with Papillary Thyroid Carcinoma.: Woo Jin Chang, Hyun Hee Jung, Sang Hyen Park, Se Hoon Sohn, Ji Sung Yoon, Hyoung Woo Lee, Kyu Chang Won, In Ho Cho; Yeungnam Univ J Med. 2010;27(2):139-145. Published online December 31, 2010; DOI: https://doi.org/10.12701/yujm.2010.27.2.139

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Abstract PDF: Cystic parathyroid adenoma is one of rare causes of hyperparathyroidism, and tends to cause increased serum level of parathyroid hormone, alkaline phosphate and serum calcium level similar to when compared to those of solid adenoma.

Dynamic CT Finding of Pelioid HCC; Case Report.: Rak Chae Son, Jae Woon Kim, Jae Chun Chang; Yeungnam Univ J Med. 2010;27(2):146-149. Published online December 31, 2010; DOI: https://doi.org/10.12701/yujm.2010.27.2.146

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Abstract PDF: Pelioid hepatocellular carcinoma (HCC), a type of atypical HCC, is a rare histologic type of HCC. The radiologic findings of the pelioid HCC is differ from the typical type of HCC. To our knowledge, this case report is the second literature to show the enhancing features of a pelioid HCC on dynamic computed tomography (CT). Here we describe the dynamic CT findings in a case of surgically confirmed pelioid HCC.

A Case of Primary Rectal Colon Mucosa associated Lymphoid Tissue Lymphoma.: Jun Suk Park, Byung Ik Jang, Jun Hyuk Choi, Kyeong Ok Kim, Min Geun Gu, Min Kyu Kang; Yeungnam Univ J Med. 2010;27(2):150-154. Published online December 31, 2010; DOI: https://doi.org/10.12701/yujm.2010.27.2.150

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Abstract PDF: The gastrointestinal tract(GI) is the most frequently involved site of mucosa associated lymphoid tissue (MALT) lymphoma. Stomach is the most common site of involvement among the GI tract. In some case of MALT lymphoma, it is detected in colon. Almost all diagnosis is established by pathological examination of the surgical or endoscopic specimens. We reported a case of rectal MALT lymphoma by colonoscopic polypectomy.

A Case of Exceptionally Rapid Growing Cardiac Myxoma.: June Ho Bae, Jae Woong Choi, Geu Ru Hong, Sung Kee Ryu, Ji Young Park, Yu Min Jung, Jae Hoon Lee, Seung Kyu Choi; Yeungnam Univ J Med. 2010;27(2):155-158. Published online December 31, 2010; DOI: https://doi.org/10.12701/yujm.2010.27.2.155

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Abstract PDF: Myxoma is the most common type of primary cardiac tumor and about 75% of myxomas occur in the left atrium of the heart. Most myxomas are diagnosed by echocardiography. The growth rate of myxoma is clearly unknown and newly developed myxoma is difficult to understand clearly the onset of growth. We describe the case of a newly developed huge left atrial myxoma (7x7 cm)which showed no echocardiographic evidence of the tumor four years ago. Four years later the patient underwent transthoracic echocardiography due to preoperative evaluation that was normal. Nine months later, she presented with dyspnea. Transthoracic echocardiography showed a large mass located in left atrium. Pathology showed a myxoma that measured 7x7 cm implying a growth rate of 0.15x0.15 cm/month.

A Case of Gastric Wall Hematoma and Ischemic Necrosis After Endoscopic Biopsy.: You Min Kim, Jin Sung Lee, Dong Hee Kim, Young Ho Sung, Sun Taek Choi, Hyun Tae Kim, Hyun Wook Lee, Keung Ok Kim; Yeungnam Univ J Med. 2010;27(2):159-164. Published online December 31, 2010; DOI: https://doi.org/10.12701/yujm.2010.27.2.159

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Abstract PDF

Hematoma of gastric wall is very rare, and occasionally associated with coagulopathy, trauma, peptic ulcer disease, and therapeutic endoscopy. Ischemic gastric necrosis is also rare because of the abundant anastomotic supply to the stomach, and it is usually associated with surgery and disruption of the major vessels. Endoscopic submucosal injection of hypertonic saline-epinephrine (HS-E) is a safe, cost-effective, and widely used therapy for hemostasis but it may cause tissue necrosis and perforation. We describe a case of gastric wall hematoma with oozing bleeding after endoscopic gastric mucosa biopsy in 71-year old woman with chronic renal failure and angina pectoris undergoing anti-platelet medication. We injected a small dose of HS-E (7ml) for controlling oozing bleeding. Two days later, endoscopy showed huge ulcer with necrotic tissue at the site of previously hematoma. Therefore we should pay particular attention for hematoma and mucosal necrosis when performing endoscopic procedure in a patients with high bleeding and atherosclerotic risk.

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A Case of Gastric Intramural Hematoma after Endoscopic Injection of Hypertonic Saline-Epinephrine for Hemostasis
Jun Hwa Song, Sin Kil Moon, Seong Deuk Baek, Jae Uk Lee, So Yeon Jung
The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2015; 15(1): 64. CrossRef
Gastric Submucosal Hematoma after Endoscopic Hemostasis in Patient with Dual Antiplatelet Therapy
Taeyun Kim, Heung Up Kim, Hyun Joo Song
The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2012; 12(2): 112. CrossRef

Three Cases of Primary Thyroid Lymphoma at a Single Institution.: Seung Jun Lee, Ji Yeun Kim, Jung Kyu Park, Sung Woo Kim, Ji Hun Kim, Tae Won Kim, Geun Jin Ha, Ho Sang Shon, Eui Dal Jung, Kyu Jang Won; Yeungnam Univ J Med. 2010;27(2):165-172. Published online December 31, 2010; DOI: https://doi.org/10.12701/yujm.2010.27.2.165

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Abstract PDF: Primary thyroid lymphoma is a relatively rare thyroid tumor and usually a non-Hodgkin type. Its most common histologic type is the diffuse large B cell lymphoma followed by mucosa-associated lymphoid tissue (MALT). It is known to be frequently associated with autoimmune thyroiditis such as Hashimoto's thyroiditis. We report three cases of thyroid lymphoma at a single institution with a review of the literature.

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