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- Original Article Gastric mucosal damage by bile acid.
- Hyun Hong Cho, Jeong Ill Suh, Keyong Hee Lee, Tae Nyeun Kim, Moon Kwan Chung, Hyun Woo Lee, Won Hee Choi, Chang Heon Yang
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Journal of Yeungnam Medical Science 1992;9(2):342-350
DOI: https://doi.org/10.12701/yujm.1992.9.2.342
Published online: December 31, 1992
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Abstract
To investigate the effect of bile acid on gastric mucosa, we performed biologic test using Sprague-Dawley rat. Mixture solution of TDCA 15mM and Hcl of pH 3 was given into stomach to one group and HCl of pH 3 was given into stomach to another group. The significant gastric mucosal change was vasodilation and edema, that was disappeared progressively. These findings suggest the bile acid and damage gastric mucosa.
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