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JYMS : Journal of Yeungnam Medical Science

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Young Ran Shim 6 Articles
A Case of Coexistent Lichen Sclerosus et Atrophicus and Morphea.
Jin Woo Park, Woo Jin Kim, Ki Baek Jeong, Dong Hoon Shin, Jong Soo Choi, Ki Hong Kim, Young Ran Shim
Yeungnam Univ J Med. 2003;20(1):99-103.   Published online June 30, 2003
DOI: https://doi.org/10.12701/yujm.2003.20.1.99
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Cases of coexistent lichen sclerosus et artrophicus and morphea have been reported. It is controversial that both diseases are single disease-spectrum or entirely separated. We encounterd a forty five year old female with a hypopigmented firm plaque on the left neck. Its histologic feature showed compact orthokeratosis, follicular plugging, atrophy of the stratum malpighii with vacuolar alteration of basal layer, and homogenization of the collagen in the upper dermis (lichen sclerosus et atrophicus). Increased thick collagen bundles were seen in the lower dermis (morphea).
Two Cases of Systemic Lupus Erythematosus with Cerebrovascular Involvement.
Bong Jun Kim, Eun Young Lee, Young Hoon Hong, Ki Do Park, Young Doo Song, Choong Ki Lee, Young Ran Shim
Yeungnam Univ J Med. 1998;15(2):371-380.   Published online December 31, 1998
DOI: https://doi.org/10.12701/yujm.1998.15.2.371
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Systemic lupus erythematosus(SLE) is an autoimmune disease which may affect many different organs and disclose various clinical manifestations. Recently central nervous system(CNS) involvement has been recognized as an increasingly significant contributor to morbidity and mortality of SLE. The clinical manifestations of CNS-lupus are highly variable and range from mild cognitive dysfunction, movement disorder, headache, psychosis to life-threatening stroke and coma. Among the neuropsychiatric disorders encountered in patients with SLE, cerebrovascular disease has been a relatively rare complication. The diagnosis and management of CNS-lupus is difficult because of the lack of useful diagnostic methods. If, cerebrovascular involvement is suspected, then aggressive treatment such as high dose steroid, immunosuppressive therapy, plasma exchange, may be required to reduce high mortality rate. We experienced 2 cases cerebrovascular disease occurring in SLE patients which presented with various neuropsychiatric manifestations. They were diagnosed as CNS-lupus by neuropsychiatric symptoms, brain MRI, and EEG, and showed good response to high dose steroid pulse therapy.
Sequential Combination Chemotherapy and Radiotherapy of an Isolated Non-Hodgkin's Lymphoma of the Larynx: Report of A Case.
Sei One Shin, Myung Se Kim, Sung Kyu Kim, Young Ran Shim
Yeungnam Univ J Med. 1997;14(2):443-450.   Published online December 31, 1997
DOI: https://doi.org/10.12701/yujm.1997.14.2.443
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AbstractAbstract PDF
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Citations

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  • Individual participant data meta-analysis of primary laryngeal lymphoma: Focusing on the clinical characteristics and prognosis
    Kyung Hee Kim, Rock Bum Kim, Seung Hoon Woo
    The Laryngoscope.2015; 125(12): 2741.     CrossRef
Expression of Oncogene Product in the Colorectal Carcinoma.
Young Ran Shim, Woo Young Jang, Kyoung Chan Choi, Joon Hyuk Choi, Won Hee Choi, Min Chul Shim
Yeungnam Univ J Med. 1995;12(2):210-225.   Published online December 31, 1995
DOI: https://doi.org/10.12701/yujm.1995.12.2.210
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The expression of p62"' and p2l can be seen in many solid tumor, but the pattern and incidence of expression were different according to organ, countries, and examiners, thus it is not definitely defined. Total 67 colorectal carcinoma in paraffin sections are analysed by immunohistochemically for evaluation of the p62and p21- expression according to the age, sex, chief complaints, location, differentiation, modified Dukes stage, using the specific monoclonal antibodies. The results were summarized as follows : The age of patients ranged from 32 years to 82 years. The mean age was 57.6 years. The expression of p 62y' and p21 was not correlated with age. Male was 29 cases(43.3%) and female was 38 cases(56.7%). The male to female ratio was 1:1.31. The and 95.0% in moderately differentiated adenocarcinoma, 90.0% and 90.0% in poorly differentiated <,;, adenocarcmoma, 100.0% and 100.0% in mucinous carcinoma. The positive rate of p62!and and p2l' was 94.1% and 88.2% in Dukes stage B,, 96.0% and 96.0% in Dukes stage B,, 100.0% and 100.0% in Dukes stage C,, 100.0% and 88.9% in Dukes stage C, and 100.0% and 100. o% in Dukes stage D. The expression of p62 y' in metastatic colorectal carcinoma showed diffuse and strongly positive reaction than primary colorectal carcinoma. The expression of p21 in primary colorectal carcinoma showed diffuse and strongly positive reaction than metastatic colorectal carcinoma.
Histopathologic findings of necrotizing lymphadenitis.
Young Ran Shim, Hae Joo Nam
Yeungnam Univ J Med. 1993;10(2):485-492.   Published online December 31, 1993
DOI: https://doi.org/10.12701/yujm.1993.10.2.485
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Necrotizing lymphadenitis was first recognised as a self-limiting lymphadenitis by Japanese workers in 1972. It is a distinct clinicopathologic entity, but can be mistaken as malignant lymphoma. We have studied clinicopathologic features in 15 cases of necrotizing lymphadenitis. This disease occurs predominantly in young adult. Male-female ratio is 2 : 1. The commonest presentation is lateral cervical lymphadenopathy. Pain, tenderness, and fever can be seen. Biopsy of the lymph nodes from all patients demonstrates the characteristic histologic features : multifocal, relatively circumscribed nodules in the cortex and/or paracortex, consisting of a mixture of activated large lymphoid cells, histiocytes and Small lymphocytes. Numerous karyorrhetic debris are present. Neutrophils and plasma cells are strikingly absent.
A case of giant lymph node hyperplasia in the spermatic cord.
Hyun Chul Shin, Young Soo Kim, Tong Choon Park, Young Ran Shim
Yeungnam Univ J Med. 1992;9(1):175-180.   Published online June 30, 1992
DOI: https://doi.org/10.12701/yujm.1992.9.1.175
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AbstractAbstract PDF
Giant lymph node hyperplasia (Castleman's disease) is a rare disease, which represents a peculiar form of lymph node hyperplasia. Generally, it has been considered as benign and localized disease but recently, revealed malignant transformation in some cases of multicentric form. It usually occurs on the mediastinum and occasionally neck, lung, axilla, mesentery, broad ligament, retroperitoneum or soft tissue of extremities. Histopathologically, it is divided into hyaline vascular or plasma cell type and the former is characterized with prominent vascular proliferation and hyalinization in the central portion and tight concentric layering of lymphocytes at the periphery of the follicles (mantle zone) and the latter is characterized by a diffuse plasma cell proliferation in the interfollicular area. From the point of view of clinical presentation, it has been divided into solitary form, which presents as a localized mass located most commonly in the mediastinum, and multicentric form, which occurs multiple location and has systemic manifestation and transformation into malignancy. Herein we report a case of Giant lymph node hyperplasia occurring in the left spermatic cord in a 58-year old male with brief review of literatures.

JYMS : Journal of Yeungnam Medical Science