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JYMS : Journal of Yeungnam Medical Science

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Yeung Ju Byun 13 Articles
Comparision of Heoatitis B Virus Markers in the Serum and the Cerebrospinal Fluid
Sang Dug Suh, Seong Min Kim, Jun Lee, Gun Ju Park, Hyun Cheol Do, Yeung Ju Byun
Yeungnam Univ J Med. 1995;12(2):282-291.   Published online December 31, 1995
DOI: https://doi.org/10.12701/yujm.1995.12.2.282
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AbstractAbstract PDF
We investigated HBV markers in serum and cerebrospinal fluid of 50 subjects with neurologic disorders or other disorders, who visited Dept. of neurology, college of medicine, Yeungnam University, from April-1 to August-31 1994 and were performed cerebrospinal fluid analysis to investigate the detection rate of HBV markers in cerebrospinal fluid and the possibility of neurologic disorders associated with HBV infection. The results were as follows. The positivity of HBsAg and. HBV prevalence rate in serum were 6 (12.04) and 37 (74.0%). Thf, number of patient with HBsAg, only anti-HBV and no markers were 6 (12.0%), 31 (62.0%) and 13 (26.0%), respectively. The positivity of HBsAg and HBV prevalence rate in cerebrospinal fluid were 3 (6%) and 18 (36.0%). The number of patient with HBsAg, only anti-HBV and no markers were 6 (100.0%), 12 (38.7%) and 0 (0.0%) respectively. The number of patient with virus associated diseases (VAD) and non virus associated diseases (NVAD) were 26 (52%) and 24 (48%). The HBV prevalence rate in serum of VAD and NVAD groups were 88.5% and 58.3% (p<0.05). The HBV prevalence rate in CSF of VAD and NVAD groups were 53.8% and 16.7% (p<0.05). The HBV prevalence rate in serum and CSF of VAD and NVAD groups were 60.9% and 28.6%. As a conclusion, the HBV markers in the CSF were partially detected at the presence of the HBV markers in serum. The prevalence rate of HBV in the CSF was increased at the HBsAg positive in the serum and the CSF was significantly increased at the VAD group than the NVAD group
Significance of Dexamethasone Suppression Test in Patients with Stroke.
Wook Nyeon Kim, Seong Min Kim, Byung Soo Kee, Mee Yeong Park, Jung Sang Hah, Yeung Ju Byun
Yeungnam Univ J Med. 1994;11(1):63-71.   Published online June 30, 1994
DOI: https://doi.org/10.12701/yujm.1994.11.1.63
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The purpose of this study was to evaluate the effect of stroke on hypothalamic-pituitary axis using dexamethasone suppression test. The effects were evaluated according to age, sex, type, size, and lesion site of stroke. There tests were performed in 62 patients with stroke(cerebral infarction, 42 cases : intracerebral hemorrage, 20 cases) and 21 disabled controlled patients without intracranial diseases at Yeungnam University Hospital from June 1992 to June 1993. The results summarized as follows. 1. Cerebral infarction showed significantly higher frequency of DST non-suppression in stroke patients than control (p<0.05). 2. Patients with left hemisphere stroke showed more frequent abnormal neuroendocrine test results (p<0.01). 3. Patients with large infarction revealed strongly non-suppressed DST results(p<0.01). 4. Significantly higher basal cortisol level in patients with cerebral infarction was noted(p<0.01). 5. There are no statistical significance between DST results and sex, age, motor impairment, type of cerebral infarction.
Driving of Motor Vehicles of the Epileptic Patients.
Yeung Ju Byun, Mee Young Park, Jung Sang Ha
Yeungnam Univ J Med. 1994;11(1):16-29.   Published online June 30, 1994
DOI: https://doi.org/10.12701/yujm.1994.11.1.16
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AbstractAbstract PDF
No abstract available.
The risk factors of recurrent ischemic stroke
Cheol Jung, Wook Nyneon Kim, Min Jeung Kim, Soek Mum Choi, Kyung Yoon Eur, Mee Young Park, Jeng Sang Hah, Yeung Ju Byun
Yeungnam Univ J Med. 1993;10(2):423-431.   Published online December 31, 1993
DOI: https://doi.org/10.12701/yujm.1993.10.2.423
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AbstractAbstract PDF
To evaluate the risk factors which are related to recurrence of ischemic stroke, we selected subjects who were admitted to YNUH due to recurrent stroke and compared their risk factors with non-recurred group- who suffered from single ischemic stroke. In the subjects, 55 of them are men and 22 were women and in the non-recurred groups, 84 of them were men and 40 were women, Subject's age ranged from 29 to 86 years (Mean 62.5years), and non-recurred group's age ranged from 27 to 90 years (Mean 60.7years), Peak incidence of ischemic stroke is in the 7th decade in both groups. Age and sex are not statistically significant for recurrence of ischemic stroke. The patient's history of diabetes mellitus, myocardial infarction, atrial fibrillation, transient attack and type or site of ischemic stroke had no significant effect statistically on the recurrent ischemic stroke. However, when the patient had previous history of hypertension or systolic blood pressure more than 160 mmHg and diastolic more than 95mmHg, there was substantial difference (P<0.05) between the two group in the recurrence of ischemic stroke. According to the above results, hypertension is most likely significant risk factor of the recurrence of ischemic stroke within 2 yers after initial one. Therefore, adequate treatment of the hypertension is important for the prevention of ischemic stroke. Further study is required for searching other risk factors.

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  • Hemiplegic Experience after Stroke among Middle Aged Man
    Soo-Yong Oh, Jeong-Seop Lee
    Journal of the Korea Academia-Industrial cooperation Society.2016; 17(5): 582.     CrossRef
  • Knowledge, health‐promoting behaviors, and biological risks of recurrent stroke among stroke patients in Korea
    Hei Ryun Lee, Ok Kyung Ham, Young Whee Lee, Insook Cho, Hyun Soo Oh, Joung‐Ho Rha
    Japan Journal of Nursing Science.2014; 11(2): 112.     CrossRef
The role of G protein in the activation of phospholipase C from bovine brain.
Jung Hye Kim, Dong Jin Lee, Yeung Ju Byun
Yeungnam Univ J Med. 1992;9(2):288-301.   Published online December 31, 1992
DOI: https://doi.org/10.12701/yujm.1992.9.2.288
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The objective of the present study was to identify the characteristics of phospholipase C (PLC) isozymes purified from bovine brain and to investigate their interrelationship with G protein. The purified PLC isozymes β, γ and δ were obtained and the characteristics of PLC activity on various concentrations of free Ca²⁺ were observed. The activity of PLC was increased with increasing Ca²⁺ concentration and the activity PLC δ was increased higher in the presence of phosphatidyl choline (PC) than in the absence of PC. For vesicle formation as the structure of cell membrane, cholic acid and deoxycholic acid as detergent on phosphatidylinositol bisphosphate (PIP₂) substrate containing PC were used, and then the activity of PLC isozymes were increased with increasing concentration of cholate, from 0.2% to 1% and were increased slightly in deoxycholate. In the PIP₂ containing phospholipid and glycolipid as brain extract, the activity of PLC isozymes were checked in 0.2-1% cholic acid. The activities of PLC isozymes were continuously increased up to 1% cholic acid. The quantitation of PLC isozymes from several bovine organs by radioimmunoassay was made. Brain was the most sufficient organ in terms of amount of PLC β and δ. A large amount of PLC δ was existed in adrenal gland. The binding capacity of GTPrS and G protein was observed and other observations of the binding effect of GTPrS-G protein and PLC monoclonal Ab-Protein A from tissue homogenate with PLC were made. From the observation the binding capacity was revealed the range of 0.11-1.49%. The effects of each type of G protein on the percent activity of purified PLC isozymes were observed. From the observation, activities of isozymes were increased in Goa & Gmix, and the activities of PLC β and δ were increased in Gβγ and Gia. Activities of PLC β and γ were decreased in Gta but PLC δ increased.
A clinical study of acute carbon monoxide intoxication.
Kyong Chan Choi, Mee Yeung Park, Jung Sang Hah, Yeung Ju Byun, Choong Suh Park
Yeungnam Univ J Med. 1991;8(1):86-97.   Published online June 30, 1991
DOI: https://doi.org/10.12701/yujm.1991.8.1.86
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To obtain the basic data of prognosis of acute carbon monoxide (CO) intoxication, one hundred and sixteen cases of CO intoxication defined by carboxyhemoglobin (COHb) and admitted via emergency room of Yeungnam University Hospital from Oct. '85 to April' 89 have been clinically analyzed and evaluated, including delayed postanoxic encephalopathy (DPE) and the following results were obtained. 1. The ratio of male to female was 1:1.5 and mental state was drowsy mostly (26.2% of 116 cases) 2. The more disturbed the mental state, the more decreased was the arterial pH and PaCO₂, which may be the result of metabolic acidosis. 3. The early laboratory findings in patients of CO intoxication were as follows: leukocytosis-65.5%, increase of hematocrit-23.3%, hyperglycemia-19.8%, increase of GPT-19.8% increase of creatinine-0.9% and glucosuria-12.1%. 4. The early findings of EKG were abnormal in 35.3%: change of rhythm-25.0%, abnormal ST segment 15.5% (change of rhythm and abnormal ST segment-5.2%) but the conduction disorder was not present. 5. The abnormal EEG above mild degree was 93.1%, of which moderate was most frequent (80.2%). 6. The incidence of DPE was 7.8% among all admitted CO patients. DPE cases had long duration of exposure time (8 hours), severe leukocytosis (20,000) and an abnormal EEG (MA).
Study on the changes of nerve conduction with wrist fixation in carpal tunnel syndrome.
Se Jin Lee, Kyung Yoon O, Mee Yeong Park, Jung Sang Hah, Yeung Ju Byun, Choong Suh Park
Yeungnam Univ J Med. 1991;8(1):79-85.   Published online June 30, 1991
DOI: https://doi.org/10.12701/yujm.1991.8.1.79
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The author studied 20 healthy adults (20 hands) as a control and 30 patients (40 hands) with carpal tunnel syndrome to evaluate the clinical usefulness of measuring nerve conduction velocity after wrist flexion in diagnosis of carpal tunnel syndrome. The median nerve conduction velocity over wrist to finger segment was measured before and after wrist flexion for 1, 2 and 5 minutes, using belly-tendon method for motor nerve distal latency (MNDL) and antidromic method for sensory nerve conduction velocity (SNCV). The results were as follows: 1. In control group, MNDL increased in 1 hand and SNCV decreased in 2 hands after wrist flexion. In patient group, MNDL increased in 2 hands and SNCV decreased in 3 hands after wrist flexion. 2. In both control and patient group, there were no significant changes in mean values of SNCV and MNDL between before and after wrist flexion. 3. Phalen's wrist flexion test was positive in 5 percent of control and 60 percent of patient group. 4. Tinel's sign was present in 10 percent of control and 33 percent of patient group.
Eaton-Lambert Syndrome with Small Cell Lung Cancer: A case report.
Kyeong Hee Lee, Moon Kwan Chung, Myung Soo Hyun, Jae Chun Chung, Hyun Woo Lee, Jung Sang Hah, Yeung Ju Byun
Yeungnam Univ J Med. 1989;6(1):171-178.   Published online June 30, 1989
DOI: https://doi.org/10.12701/yujm.1989.6.1.171
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Eaton Lambert Syndrome (ELS) is a disorder of neuromuscular transmission. The defect of neuromuscular transmission is due to decrease in the release of acetylcholine quanta from nerve terminal. This syndrome is frequently associated with bronchogenic carcinoma. The diagnosis is established by electromyography, which characteristically shows 1) low amplitude of evoked compound muscle potential to a single supramaximal stimulus on nerve, 2) significant decremental response at low rates of stimulation 3) marked incremental response at high rates of stimulation. Our patient is 52year old man with dyspnea, coughing and muscle weakness of proximal lower limbs. He has small cell lung cancer and associated with ELS, Superior vena cava syndrome and has metastatic lesion on right supraclavicular lymph node confirmed by pathology. Metastatic mass and SVC syndrome are marked improved following chemotherapy and radiotherapy, however follow up EMG finding does not improved. We are here reporting one case which considered compatible for ELS, with a few elementary reviewed literatures.
A Study of Nerve Conduction Velocity of Normal Adults.
Kyoung Chan Choi, Jung Sang Hah, Yeung Ju Byun, Choong Suh Park, Chang Heon Yang
Yeungnam Univ J Med. 1989;6(1):151-163.   Published online June 30, 1989
DOI: https://doi.org/10.12701/yujm.1989.6.1.151
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AbstractAbstract PDF
Nerve conduction studies help delineate the extent and distribution of the neural lesion. The nerve conduction was studied on upper (median, ulnar and radial nerves) and lower (personal, posterior tibial and sural nerves) extremities in 83 healthy subjects 23 to 66 years of age, and normal values were established (Table 1). The mean motor terminal latency (TL): median, 3.6 (±0.6) milliseconds; ulnar, 2.9 (±0.5) milliseconds; radial nerve, 2.3 (±0.4) milliseconds. Mean motor nerve conduction velocity (MNCV) along distal and proximal segments: median, 61.2 (±9.1) (W-E) and 57.8 (±13.2) (E-Ax) meters per second; ulnar, 63.7 (±9.1) (W-E) and 50.6 (±10.0) meters per second. Mean sensory nerve conduction velocity (SNCV): median, 34.7 (±6.7) (F-W), 63.7 (±7.1) (W-E) and 62.8 (±12.3) (E-Ax) meters per second; ulnar, 38.0 (±6.7) (F-W), 63.4 (±7.5) (W-E) and 57.0 (±10.1) (E-Ax) meters per second; radial, 45.3 (±6.8) (F-W) and 64.2 (±11.0) (W-E) meters per second; sural nerve, 43.4 (±6.1) meters per second. The amplitudes of action potential and H-reflex were also standardized. Mean H latency was 28.4 (±3.2) milliseconds. And, the fundamental principles, several factors altering the rate of nerve conduction and clinical application of nerve stimulation techniques were reviewed.

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  • Skin type and nerve effects on cortical tactile processing: a somatosensory evoked potentials study
    Marco Guidotti, Clément Beaurieux, Pierre Marionnaud, Frédérique Bonnet-Brilhault, Claire Wardak, Marianne Latinus
    Journal of Neurophysiology.2023; 130(3): 547.     CrossRef
Clinical Study of CT-diagnosed Olivopontocerebellar Atrophies.
Mee Yeong Park, Khyoung Yhun O, Jung Sang Hah, Yeung Ju Byun, Choong Suh Park
Yeungnam Univ J Med. 1988;5(2):87-93.   Published online December 31, 1988
DOI: https://doi.org/10.12701/yujm.1988.5.2.87
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The diagnosis of OPCA could be made clinically with important aid of brain CT scanning, although the definite and conclusive diagnosis only by postmortem pathological determination. We reviewed, clinically and with brain CT examination, 12 cases of patients with OPCA who were admitted to the Yeungnam University Hospital for a recent 5 years. The result were as following: 1. The distribution of age is from 49 to 72, mainly 50 to 60. Man is more frequent than women at the 4.5 times. 2. The interval period from Sx. Onset to diagnosis is 1 year to 6 years. 3. The usual initial Sxs. Were dizziness (58%), ataxia (33%), and other less frequent Sxs. Were weakness of low extremities, dysarthria, headache and urinary incontinence. The clinical manifestations at the initial diagnosis were cerebellar disturbance (100%), dysarthria (83%), and increased deep tendon reflexes (58%). 4. The results of brain CT finding are like this: the width of cerebellar sulci is more than 1mm, other 4 cases more than 2mm. the width of cerebellar pontine cistern of the patient if usually 3 to 4mm, other 2 cases extended to the 5 mm. the A. P and lateral lengths of 4th. ventricle is 4 mm and 4 to 8 mm respectively. 6 cases of whole patients show coincidentally cerebral atrophy.
A Case of One and A Half Syndrome.
Khyoung Yhun O, Jung Sang Hah, Yeung Ju Byun, Choong Suh Park
Yeungnam Univ J Med. 1988;5(1):167-172.   Published online June 30, 1988
DOI: https://doi.org/10.12701/yujm.1988.5.1.167
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One and a half syndrome is an ipsilateral gaze paresis or palsy combined with and internuclear ophthalmoplegia on contralateral gaze. The lesion site is at the paramedian pontine reticular formation and the adjacent MLF. The common causes are unilateral pontine infarction and multiple sclerosis. We experienced a case of one and a half syndrome which has a suspected small pontine infarct.
A case of Cryptococcal Meningitis.
Khyoung Yhun O, Yeung Ju Byun, Choong Suh Park, Chang Ho Jeon, Chung Sook Kim
Yeungnam Univ J Med. 1987;4(1):139-143.   Published online August 31, 1987
DOI: https://doi.org/10.12701/yujm.1987.4.1.139
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The clinical picture and CSF findings in cryptococcal meningitis may be identical with those of tuberculous meningitis. The differential diagnosis can be made by finding the budding yeast organism in the counting chamber of in stained smear, the detection of cryptococcal antigen in CSF by the latex agglutination test, and by culture of the fungus on Sabouraud agar. We experienced a case of cryptococcal meningitis in the 48 years old woman, which was confirmed by Indian ink preparation and culture.
A Case Report of Conn's Myopathy.
Bo Wan Suh, Khyoung Yhun O, Yeung Ju Byun, Choong Suh Park, Hong Jin Kim
Yeungnam Univ J Med. 1987;4(1):133-137.   Published online August 31, 1987
DOI: https://doi.org/10.12701/yujm.1987.4.1.133
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Myopathy in primary aldosteronism in relatively rare disease in Korea. A 42-year-old woman with hypokalemic periodic paralysis, proximal muscle weakness and hypertension was found to have myopathy associated with adenoma in the right adrenal gland. She showed marked elevation of muscle enzymes and myopathic pattern in EMG.

JYMS : Journal of Yeungnam Medical Science