- Significance of albumin to globulin ratio as a predictor of febrile urinary tract infection after ureteroscopic lithotripsy
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Seung Yun Yi, Dong Jin Park, Kyungchan Min, Jae-Wook Chung, Yun-Sok Ha, Bum Soo Kim, Hyun Tae Kim, Tae-Hwan Kim, Eun Sang Yoo
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Yeungnam Univ J Med. 2021;38(3):225-230. Published online April 20, 2021
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DOI: https://doi.org/10.12701/yujm.2021.00955
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Abstract
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- Background
We aimed to analyze the effectiveness of albumin to globulin ratio (AGR) in predicting postoperative febrile urinary tract infection (fUTI) after ureteroscopic lithotripsy (URS) and retrograde intrarenal surgery (RIRS).
Methods From January 2013 to May 2018, 332 patients underwent URS and RIRS. The rate of postoperative fUTI and risk factors for postoperative fUTI were analyzed using logistic regression. Patients were divided into postoperative fUTI and non-postoperative fUTI (non-fUTI) groups. AGR with other demographic and perioperative data were compared between the two groups to predict the development of fUTI after URS.
Results Of the 332 patients, postoperative fUTI occurred in 41 (12.3%). Preoperative pyuria, microscopic hematuria, diabetes mellitus, hypoalbuminemia, and hyperglobulinemia were more prevalent in the fUTI group. Patients in the fUTI group had larger stone size, lower preoperative AGR, longer operation time, and longer preoperative antibiotic coverage period. In a multivariable logistic analysis, preoperative pyuria, AGR, and stone size were independently correlated with postoperative fUTI (p<0.001, p=0.008, and p=0.041, respectively). Receiver operating curve analysis showed that the cutoff value of AGR that could predict a high risk of fUTI after URS was 1.437 (sensitivity, 77.3%; specificity, 76.9%), while the cutoff value of stone size was 8.5 mm (sensitivity, 55.3%; specificity, 44.7%).
Conclusion This study demonstrated that preoperative pyuria, AGR, and stone size can serve as prognostic factors for predicting fUTI after URS.
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Citations
Citations to this article as recorded by
- Common hematological and biochemical parameters for predicting urinary tract infections in geriatric patients with hip fractures
Wanyun Tang, Wei Yao, Wei Wang, Qiaomei Lv, Wenbo Ding, RenJian He Frontiers in Medicine.2024;[Epub] CrossRef - Metabolomic Changes Associated with AGXT2 Genotype Variants and Stone Formation in a Colony of Cats
Jean A. Hall, Jeffrey A. Brockman, John J. Brejda, Dennis E. Jewell Genes.2024; 15(10): 1264. CrossRef - An analysis of bacteriuria rates after endourological procedures
Nethravathy Billava Seenappa, Maneesh Sinha, Thyagaraj Krishna Prasad, Venkatesh Krishnamoorthy International Journal of Urological Nursing.2023; 17(1): 45. CrossRef - Nutritional and Inflammatory Indices and the Risk of Surgical Site Infection After Fragility Hip Fractures: Can Routine Blood Test Point to Patients at Risk?
Tal Frenkel Rutenberg, Rana Gabarin, Vitali Kilimnik, Efrat Daglan, Moti Iflah, Shani Zach, Shai Shemesh Surgical Infections.2023; 24(7): 645. CrossRef - Prognostic value of albumin-to-globulin ratio in COVID-19 patients: A systematic review and meta-analysis
Juan R. Ulloque-Badaracco, Melany D. Mosquera-Rojas, Enrique A. Hernandez-Bustamante, Esteban A. Alarcón-Braga, Percy Herrera-Añazco, Vicente A. Benites-Zapata Heliyon.2022; 8(5): e09457. CrossRef
- Oncological and functional outcomes following robot-assisted laparoscopic radical prostatectomy at a single institution: a minimum 5-year follow-up
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Jun-Koo Kang, Jae-Wook Chung, So Young Chun, Yun-Sok Ha, Seock Hwan Choi, Jun Nyung Lee, Bum Soo Kim, Ghil Suk Yoon, Hyun Tae Kim, Tae-Hwan Kim, Tae Gyun Kwon
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Yeungnam Univ J Med. 2018;35(2):171-178. Published online December 31, 2018
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DOI: https://doi.org/10.12701/yujm.2018.35.2.171
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Abstract
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- Background
To evaluate mid-term oncological and functional outcomes in patients with prostate cancer treated by robot-assisted laparoscopic radical prostatectomy (RALP) at our institution.
Methods We retrospectively reviewed the medical records of 128 patients with prostate cancer who underwent RALP at our institution between February 2008 and April 2010. All patients enrolled in this study were followed up for at least 5 years. We analyzed biochemical recurrence (BCR)-free survival using a Kaplan-Meier survival curve analysis and predictive factors for BCR using multivariate Cox regression analysis. Continence recovery rate, defined as no use of urinary pads, was also evaluated.
Results Based on the D’Amico risk classification, there were 30 low-risk patients (23.4%), 47 intermediaterisk patients (38.8%), and 51 high-risk patients (39.8%), preoperatively. Based on pathological findings, 50.0% of patients (64/128) showed non-organ confined disease (≥T3a) and 26.6% (34/128) had high grade disease (Gleason score ≥8). During a median follow-up period of 71 months (range, 66-78 months), the frequency of BCR was 33.6% (43/128) and the median BCR-free survival was 65.9 (0.4-88.0) months. Multivariate Cox regression analysis revealed that high grade disease (Gleason score ≥8) was an independent predictor for BCR (hazard ratio=4.180, 95% confidence interval=1.02-17.12, p=0.047). In addition, a majority of patients remained continent following the RALP procedure, without the need for additional intervention for post-prostatectomy incontinence.
Conclusion Our study demonstrated acceptable outcomes following an initial RALP procedure, despite 50% of the patients investigated demonstrating high-risk features associated with non-organ confined disease.
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Citations
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- Prediction of a positive surgical margin and biochemical recurrence after robot-assisted radical prostatectomy
Ching-Wei Yang, Hsiao-Hsien Wang, Mohamed Fayez Hassouna, Manish Chand, William J. S. Huang, Hsiao-Jen Chung Scientific Reports.2021;[Epub] CrossRef
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