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Jong Geol Jang 4 Articles
Diagnosis and treatment of multidrug-resistant tuberculosis
Jong Geol Jang, Jin Hong Chung
Yeungnam Univ J Med. 2020;37(4):277-285.   Published online September 4, 2020
DOI: https://doi.org/10.12701/yujm.2020.00626
  • 15,550 View
  • 516 Download
  • 37 Crossref
AbstractAbstract PDF
Tuberculosis (TB) is still a major health problem worldwide. Especially, multidrug-resistant TB (MDR-TB), which is defined as TB that shows resistance to both isoniazid and rifampicin, is a barrier in the treatment of TB. Globally, approximately 3.4% of new TB patients and 20% of the patients with a history of previous treatment for TB were diagnosed with MDR-TB. The treatment of MDR-TB requires medications for a long duration (up to 20–24 months) with less effective and toxic second-line drugs and has unfavorable outcomes. However, treatment outcomes are expected to improve due to the introduction of a new agent (bedaquiline), repurposed drugs (linezolid, clofazimine, and cycloserine), and technological advancement in rapid drug sensitivity testing. The World Health Organization (WHO) released a rapid communication in 2018, followed by consolidated guidelines for the treatment of MDR-TB in 2019 based on clinical trials and an individual patient data meta-analysis. In these guidelines, the WHO suggested reclassification of second-line anti-TB drugs and recommended oral treatment regimens that included the new and repurposed agents. The aims of this article are to review the treatment strategies of MDR-TB based on the 2019 WHO guidelines regarding the management of MDR-TB and the diagnostic techniques for detecting resistance, including phenotypic and molecular drug sensitivity tests.

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  • Computational insights into potential marine natural products as selective inhibitors of Mycobacterium tuberculosis InhA: A structure-based virtual screening study
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    Computational Biology and Chemistry.2024; 108: 107991.     CrossRef
  • Targeting of essential mycobacterial replication enzyme DnaG primase revealed Mitoxantrone and Vapreotide as novel mycobacterial growth inhibitors**
    Waseem Ali, Salma Jamal, Rishabh Gangwar, Faraz Ahmed, Rahul Sharma, Meetu Agarwal, Javaid Ahmad Sheikh, Abhinav Grover, Sonam Grover
    Molecular Informatics.2024;[Epub]     CrossRef
  • A Comprehensive Review on Long vs. Short Regimens in Multidrug-Resistant Tuberculosis (MDR-TB) Under Programmatic Management of Drug-Resistant Tuberculosis (PMDT)
    Ashwin Karnan, Ulhas Jadhav, Babaji Ghewade, Anjana Ledwani, Poorna Shivashankar
    Cureus.2024;[Epub]     CrossRef
  • Design, synthesis and biological evaluation of novel pyrido-[2,3-d]-pyrimidin-2-amine analogues as antimycobacterial agents
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    Journal of Molecular Structure.2024; 1303: 137600.     CrossRef
  • Synthesis and Structure–Activity Relationship of 2,6-Disubstituted Thiosemicarbazone Derivatives of Pyridine as Potential Antituberculosis Agents
    Dagmara Ziembicka, Katarzyna Gobis, Małgorzata Szczesio, Andrzej Olczak, Ewa Augustynowicz-Kopeć, Agnieszka Głogowska, Izabela Korona-Głowniak, Krzysztof Bojanowski
    Materials.2023; 16(1): 448.     CrossRef
  • Multidrug-Resistant TB (MDR-TB) and Extensively Drug-Resistant TB (XDR-TB) Among Children: Where We Stand Now
    Kona Chowdhury, Rahnuma Ahmad, Susmita Sinha, Siddhartha Dutta, Mainul Haque
    Cureus.2023;[Epub]     CrossRef
  • Anxiety and depression level of patients with multidrug-resistant tuberculosis (MDR-TB) in two hospitals in Banten province, Indonesia
    Tirta Darmawan Susanto, Allen Widysanto, Darien Alfa Cipta, Arron Tanara, Ghivarell Rizkie Wirawan, Adeline Bercadina Kosim, Christabella Maria Djoni, Ervinna Tantri, Chandni Kumar, Chelsie Angelius
    Dialogues in Health.2023; 2: 100115.     CrossRef
  • Characteristics of Previous Tuberculosis Treatment History in Patients with Treatment Failure and the Impact on Acquired Drug-Resistant Tuberculosis
    Soedarsono Soedarsono, Ni Made Mertaniasih, Tutik Kusmiati, Ariani Permatasari, Wiwik Kurnia Ilahi, Amelia Tantri Anggraeni
    Antibiotics.2023; 12(3): 598.     CrossRef
  • Evolution of tuberculosis diagnostics: From molecular strategies to nanodiagnostics
    Srestha Mukherjee, Summaya Perveen, Anjali Negi, Rashmi Sharma
    Tuberculosis.2023; 140: 102340.     CrossRef
  • Assessment of the Diagnostic Utility of GeneXpert Mycobacterium tuberculosis/Rifampicin (MTB/RIF) Assay in the Suspected Cases of Tuberculous Meningitis
    Sakshi Patel, Malti Dadheech, Anand K Maurya, Jitendra Singh, Shashank Purwar, Nirendra Rai, Radha Sarawagi, Ankur Joshi, Sagar Khadanga
    Cureus.2023;[Epub]     CrossRef
  • Tandem LC-MS Identification of Antitubercular Compounds in Zones of Growth Inhibition Produced by South African Filamentous Actinobacteria
    Daniel J. Watson, Lubbe Wiesner, Tlhalefo Matimela, Denzil Beukes, Paul R. Meyers
    Molecules.2023; 28(11): 4276.     CrossRef
  • Drug-Resistant Tuberculosis Stigma Among HealthCare Workers Toward the Development of a Stigma-Reduction Strategy: A Scoping Review
    Lolita Liboon Aranas, Khorshed Alam, Prajwal Gyawali, Rashidul Mahumud Alam
    INQUIRY: The Journal of Health Care Organization, Provision, and Financing.2023;[Epub]     CrossRef
  • Quality Mindset: The Missing Ingredient in Tuberculosis Care and Control in Togo
    Kossivi Agbélénko Afanvi, Mohammed Fall Dogo, Koffi Atsu Aziagbé, Komi Séraphin Adjoh, Koumavi Kristoli Didier Ekouévi
    European Journal of Theoretical and Applied Sciences.2023; 1(4): 36.     CrossRef
  • Machine Learning of the Whole Genome Sequence of Mycobacterium tuberculosis: A Scoping PRISMA-Based Review
    Ricardo Perea-Jacobo, Guillermo René Paredes-Gutiérrez, Miguel Ángel Guerrero-Chevannier, Dora-Luz Flores, Raquel Muñiz-Salazar
    Microorganisms.2023; 11(8): 1872.     CrossRef
  • Cotreatment With Clofazimine and Rapamycin Eliminates Drug-Resistant Tuberculosis by Inducing Polyfunctional Central Memory T-Cell Responses
    Dhiraj Kumar Singh, Ashima Bhaskar, Isha Pahuja, Aishwarya Shaji, Barnani Moitra, Yufang Shi, Ved Prakash Dwivedi, Gobardhan Das
    The Journal of Infectious Diseases.2023; 228(9): 1166.     CrossRef
  • Treatment of drug-resistant tuberculosis in children and young adolescents in Brazil
    Fernanda Bruzadelli Paulino da Costa, Thaís Zamboni Berra, Jaqueline Garcia de Almeida Ballestero, Patricia Bartholomay Oliveira, Daniele Maria Pelissari, Yan Mathias Alves, Antônio Carlos Vieira Ramos, Juliana Queiroz Rocha de Paiva, Titilade Kehinde Aya
    Journal of Clinical Tuberculosis and Other Mycobacterial Diseases.2023; 33: 100388.     CrossRef
  • Tackling Drug-Resistant Tuberculosis: New Challenges from the Old Pathogen Mycobacterium tuberculosis
    Giuseppe Mancuso, Angelina Midiri, Silvia De Gaetano, Elena Ponzo, Carmelo Biondo
    Microorganisms.2023; 11(9): 2277.     CrossRef
  • Drug-resistant Monoarticular Wrist Joint Tuberculosis in Renal Transplant Recipient with Literature Review
    Jasmine Sethi, Vignesh Subramani, Rajender Kumar, Shivakumar Patil, Ashish Sharma
    Indian Journal of Transplantation.2023; 17(3): 371.     CrossRef
  • Predictive capabilities of baseline radiological findings for early and late disease outcomes within sensitive and multi-drug resistant tuberculosis cases
    Gabriel Rosenfeld, Andrei Gabrielian, Darrell Hurt, Alex Rosenthal
    European Journal of Radiology Open.2023; 11: 100518.     CrossRef
  • Nanocarriers in Tuberculosis Treatment: Challenges and Delivery Strategies
    Mahesh Kumar, Tarun Virmani, Girish Kumar, Rohitas Deshmukh, Ashwani Sharma, Sofia Duarte, Pedro Brandão, Pedro Fonte
    Pharmaceuticals.2023; 16(10): 1360.     CrossRef
  • A systematic review and meta-analysis on the correlation between HIV infection and multidrug-resistance tuberculosis
    Yulong Song, Qian Jin, Jihai Qiu, Dan Ye
    Heliyon.2023; 9(11): e21956.     CrossRef
  • Current Insights into Diagnosing and Treating Neurotuberculosis in Adults
    Sofiati Dian, Ahmad Rizal Ganiem, Lindsey HM te Brake, Arjan van Laarhoven
    CNS Drugs.2023; 37(11): 957.     CrossRef
  • Economic burden of multidrug-resistant tuberculosis on patients and households: a global systematic review and meta-analysis
    Temesgen Yihunie Akalu, Archie C. A. Clements, Haileab Fekadu Wolde, Kefyalew Addis Alene
    Scientific Reports.2023;[Epub]     CrossRef
  • Nano vs Resistant Tuberculosis: Taking the Lung Route
    Deepika Sharma, Pooja, Sunita Nirban, Smriti Ojha, Tarun Kumar, Neha Jain, Najwa Mohamad, Pradeep Kumar, Manisha Pandey
    AAPS PharmSciTech.2023;[Epub]     CrossRef
  • Multi-Drug Resistance Tuberculosis (MDR-TB) Challenges in India: A Review
    Deepak Vishwakarma, Abhay Gaidhane, Sweta Sahu, Ashwini S Rathod
    Cureus.2023;[Epub]     CrossRef
  • Multidrug-resistant Tuberculosis and its Implication with COVID-19
    Jasmine Arya, Sweety Dahiya, Anil Kumar Chhillar
    Coronaviruses.2023;[Epub]     CrossRef
  • Tuberculosis drug discovery: Progression and future interventions in the wake of emerging resistance
    Summaya Perveen, Diksha Kumari, Kuljit Singh, Rashmi Sharma
    European Journal of Medicinal Chemistry.2022; 229: 114066.     CrossRef
  • Abdominal Tuberculosis Mimicking Ovarian Cancer: A Case Report and Review of the Literature
    Ikhwan Rinaldi, Abdul Muthalib, Djaja Gosal, Teguh Wijayadi, Barlian Sutedja, Tjondro Setiawan, Andika Gunawan, Nelly Susanto, Lingga Magdalena, Diah Rini Handjari, Fetisari Kurniawan, Aisyah Rifani, Kevin Winston
    International Medical Case Reports Journal.2022; Volume 15: 169.     CrossRef
  • Pediatric Tuberculosis Management: A Global Challenge or Breakthrough?
    Lehlogonolo N. F. Maphalle, Bozena B. Michniak-Kohn, Modupe O. Ogunrombi, Oluwatoyin A. Adeleke
    Children.2022; 9(8): 1120.     CrossRef
  • Various approaches to improving adherence of patients with tuberculosis. Prospects for the use of additive technologies in TB practice
    A. G. Naumov, A. S. Shprykov
    PULMONOLOGIYA.2022; 34(1): 80.     CrossRef
  • Antimicrobial Peptides as Potential Anti-Tubercular Leads: A Concise Review
    Gabriel S. Oliveira, Raquel P. Costa, Paula Gomes, Maria Salomé Gomes, Tânia Silva, Cátia Teixeira
    Pharmaceuticals.2021; 14(4): 323.     CrossRef
  • Treatment of Human Babesiosis: Then and Now
    Isaline Renard, Choukri Ben Mamoun
    Pathogens.2021; 10(9): 1120.     CrossRef
  • Novel mutations detected from drug resistant Mycobacterium tuberculosis isolated from North East of Thailand
    Ei Phoo Thwe, Wises Namwat, Porntip Pinlaor, Kulrattana Rueangsak, Arunnee Sangka
    World Journal of Microbiology and Biotechnology.2021;[Epub]     CrossRef
  • On the Mechanism of Development of Autoimmune Diseases Following Exposure to Inactivated Mycobacterium tuberculosis
    SV Skupnevskiy, GM Trukhina, EG Pukhaeva, AK Badtiev, FK Rurua, FE Batagova, ZhG Farnieva
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  • Oral regimen for multi-drug-resistant TB can promote patient-centred and community-based treatment
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  • Adverse effects induced by second-line antituberculosis drugs: an update based on last WHO treatment recommendations for drug-resistant tuberculosis
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    Pneumologia.2021; 70(3): 117.     CrossRef
  • Advances in the science and treatment of respiratory diseases
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    Yeungnam University Journal of Medicine.2020; 37(4): 251.     CrossRef
Adrenocorticotropic hormone (ACTH)-producing pheochromocytoma presented as Cushing syndrome and complicated by invasive aspergillosis.
Jae Ho Cho, Da Eun Jeong, Jae Young Lee, Jong Geol Jang, Jun Sung Moon, Mi Jin Kim, Ji Sung Yoon, Kyu Chang Won, Hyoung Woo Lee
Yeungnam Univ J Med. 2015;32(2):132-137.   Published online December 31, 2015
DOI: https://doi.org/10.12701/yujm.2015.32.2.132
  • 1,731 View
  • 10 Download
  • 3 Crossref
AbstractAbstract PDF
Adrenocorticotropic hormone (ACTH)-producing pheochromocytoma has been rarely reported, whereas only a few cases of Cushing syndrome accompanied by opportunistic infections have been reported. We experienced a patient with pheochromocytoma with ectopic Cushing syndrome complicated by invasive aspergillosis. A 35-year-old woman presented with typical Cushingoid features. Her basal plasma cortisol, ACTH, and 24-hour urine free cortisol levels were significantly high, and 24-hour urine metanephrine and catecholamine levels were slightly elevated. The endogeneous cortisol secretion was not suppressed by either low- or high-dose dexamethasone. Abdominal computed tomography (CT) revealed a heterogeneous enhancing mass measuring approximately 2.5 cm in size in the left adrenal gland. No definitive mass lesion was observed on sellar magnetic resonance imaging. On fluorine-18 fluorodeoxyglucose positron emission tomography/CT, a hypermetabolic nodule was observed in the left upper lung. Thus, we performed a percutaneous needle biopsy, which revealed inflammation, not malignancy. Thereafter, we performed a laparoscopic left adrenalectomy, and its pathologic finding was a pheochromocytoma with positive immunohistostaining for ACTH. After surgery, the biochemistry was normalized, but the clinical course was fatal despite intensive care because of the invasive aspergillosis that included the lungs, retina, and central nervous system.

Citations

Citations to this article as recorded by  
  • Ectopic ACTH- and/or CRH-Producing Pheochromocytomas
    Patrick F Elliott, Thomas Berhane, Oskar Ragnarsson, Henrik Falhammar
    The Journal of Clinical Endocrinology & Metabolism.2021; 106(2): 598.     CrossRef
  • Ectopic adrenocorticotrophic hormone syndrome (EAS) with phaeochromocytoma: a challenging endocrine case with a happy ending
    Sharifah Faradila Wan Muhamad Hatta, Leoni Lekkakou, Ananth Viswananth, Harit Buch
    BMJ Case Reports.2019; 12(8): e230636.     CrossRef
  • Severe Cushing Syndrome Due to an ACTH-Producing Pheochromocytoma: A Case Presentation and Review of the Literature
    Jenan N Gabi, Maali M Milhem, Yara E Tovar, Emhemmid S Karem, Alaa Y Gabi, Rodhan A Khthir
    Journal of the Endocrine Society.2018; 2(7): 621.     CrossRef
An overlap syndrome of Churg-Strauss syndrome and rheumatoid arthritis.
Seung Il Bae, Jong Geol Jang, Hun Tae Kim, Hee Yun Ahn, Min Jung Kim, Hyun Je Kim, Choong Ki Lee, Young Hoon Hong
Yeungnam Univ J Med. 2015;32(2):127-131.   Published online December 31, 2015
DOI: https://doi.org/10.12701/yujm.2015.32.2.127
  • 1,881 View
  • 5 Download
AbstractAbstract PDF
Churg-Strauss syndrome (CSS) is a necrotizing vasculitis with extra-, peri-vascular eosinophilic infiltration. Chronic symmetric polyarthritis with the presence of rheumatoid factor (RF) and anti-cyclic citrullinated peptide antibody are the mainstay of rheumatoid arthritis (RA) diagnosis. Mononeuritis multiplex is a peripheral neuropathy involving more than 2 separate nerve areas. A 62-year-old male patient was referred for left foot drop and polyarthritis of both hands and feet for 4 months. During evaluation, mononeuritis multiplex was detected on nerve conduction study and electromyography tests: vasculitis with neutrophil, eosinophil, and lymphocyte infiltration on peroneal nerve biopsy. A positive response to methacholin and bronchodilator was observed on the pulmonary function test. Radiologic tests showed peri-articular soft tissue swelling and osteopenia on both hand and foot. Marked peripheral eosinophilia, high RF, and positive perinuclear anti-neutrophil cytoplasmic antibody were detected on blood tests. Here, we report on a patient with overlap syndrome of CSS and RA with review of the relevant literature, from which a few references to overlap syndrome of CSS and RA were available.
Severe hyponatremia and seizures after bowel preparation with low-volume polyethylene glycol plus ascorbic acid solution.
Jae Young Lee, Byung Ik Jang, Yoon Jeong Nam, Jay Song, Min Cheol Kim, Seung Min Chung, Jong Geol Jang, Jae Ho Cho
Yeungnam Univ J Med. 2015;32(1):55-59.   Published online June 30, 2015
DOI: https://doi.org/10.12701/yujm.2015.32.1.55
  • 1,939 View
  • 8 Download
AbstractAbstract PDF
The widely used polyethylene glycol (PEG)-based solutions have been proven effective for bowel preparation when 4 L of the solution is administered before colonoscopy. However, large volumes of the solutions are generally poorly tolerated. A new PEG-based solution consisting of 2 L of PEG and a high dose of ascorbic acid has recently become available. Electrolyte abnormalities caused by PEG-based solutions have rarely been reported. We report on a case of acute severe hyponatremia with associated generalized tonic-clonic seizures after bowel preparation with a low-volume PEG plus ascorbic acid solution in a 74-year-old woman with no history of seizures. She took a beta blocker, an angiotensin-converting enzyme inhibitor, and glimepiride for hypertension and diabetes mellitus. She showed general weakness, nausea, agitation, muscle cramping, and seizures after ingestion of the PEG plus ascorbic acid solution. Her serum sodium level was 112 mEq/L. Her symptoms improved after intravenous administration of hypertonic saline. Physicians should pay attention to screening for electrolytes and development of neurological symptoms during bowel preparation.

JYMS : Journal of Yeungnam Medical Science