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JYMS : Journal of Yeungnam Medical Science

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Hyun Uk Chung 1 Article
Ocular adnexal mucosa-associated lymphoid tissue lymphoma: a narrative review
Hyun Uk Chung, Jun Hyuk Son
J Yeungnam Med Sci. 2022;39(1):3-11.   Published online September 15, 2021
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  • 4 Citations
AbstractAbstract PDF
Lymphoma is the most common primary tumor of the orbit, accounting for 55% of all orbital malignancies. When divided into histopathological subtypes, extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) comprises the largest proportion. Clinical manifestations are unspecific, but in patients with slow-growing painless orbital mass, or red conjunctival lesion suggestive of ‘salmon patch’, ocular adnexa lymphoma (OAL) should be suspected. Although the pathogenetic mechanism of ocular adnexal MALT lymphoma (OAML) is not yet fully understood, the relationship between OAML and Chlamydia psittaci has been hypothesized recently, similar to that between gastric MALT lymphoma and Helicobacter pylori. This suggests a new treatment option for OAML; bacterial eradication therapy with systemic antibiotics. Several other treatment methods for OAML have been introduced, but no treatment guidelines have been established yet. In this article, we summarize the current knowledge on the clinical features, pathogenesis, diagnostic methods, therapeutic strategies, and prognosis of OAML.


Citations to this article as recorded by  
  • Radiomics analysis of T1WI and T2WI magnetic resonance images to differentiate between IgG4-related ophthalmic disease and orbital MALT lymphoma
    Yuchao Shao, Yuqing Chen, Sainan Chen, Ruili Wei
    BMC Ophthalmology.2023;[Epub]     CrossRef
  • Etiopathogenesis of primary acquired nasolacrimal duct obstruction (PANDO)
    Mohammad Javed Ali
    Progress in Retinal and Eye Research.2023; 96: 101193.     CrossRef
  • The Biology of Ocular Adnexal Marginal Zone Lymphomas
    Patricia Johansson, Anja Eckstein, Ralf Küppers
    Cancers.2022; 14(5): 1264.     CrossRef
  • One Case of Conjunctival MALT Lymphoma and Literature Review
    旭霞 李
    Advances in Clinical Medicine.2022; 12(08): 7586.     CrossRef

JYMS : Journal of Yeungnam Medical Science