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JYMS : Journal of Yeungnam Medical Science

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Eunjeong Kang 1 Article
Tumoral calcinosis and calciphylaxis treated with subtotal parathyroidectomy and sodium thiosulphate.
Hyunjeong Cho, Yongjin Yi, Eunjeong Kang, Seokwoo Park, Eun Jin Cho, Sung Tae Cho, Rho Won Chun, Kyu Eun Lee, Kook Hwan Oh
Yeungnam Univ J Med. 2016;33(1):68-71.   Published online June 30, 2016
DOI: https://doi.org/10.12701/yujm.2016.33.1.68
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Tumoral calcinosis (TC) is a condition resulting from extensive calcium phosphate precipitation, primarily in the periarticular tissues around major joints. Calciphylaxis is a fatal ischemic vasculopathy mainly affecting dermal blood vessels and subcutaneous fat. This syndrome is rare and predominantly occurs in patients with end-stage renal disease. Here, we report on a rare case involving a patient with TC complicated with calciphylaxis. Our patient was a 31-year-old man undergoing hemodialysis who presented with masses on both shoulders and necrotic cutaneous ulcers, which were associated with secondary hyperparathyroidism, on his lower legs. He underwent subtotal parathyroidectomy, and sodium thiosulfate (STS) was administered for 27 weeks. Twenty months after beginning the STS treatment course, he experienced dramatic relief of his TC and calciphylaxis.

JYMS : Journal of Yeungnam Medical Science