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HOME > J Yeungnam Med Sci > Volume 24(2 Suppl); 2007 > Article
Case Report A Case of Esophageal Bullous Pemphigoid Manifestated by Upper Gastrointestinal Bleeding
Kyeong Ok Kim, Byung Ik Jang, Jong Ryul Eun, Tae Nyun Kim
Journal of Yeungnam Medical Science 2007;24(2 Suppl):S671-675
DOI: https://doi.org/10.12701/yujm.2007.24.2S.S671
Published online: December 31, 2007
Department of Internal Medicine, College of Medicine, Yeungnam University, Daegu, Korea
Corresponding author:  Byung Ik Jang, Tel: (053) 620-3830, Fax: (053) 654-8386, 
Email: jbi@med.yu.ac.kr
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Bullous pemphiogid (BP) is a chronic vesicular disorder and an autoimmune disease which has an autoantibodies to hemidesmosime in the keratinocyte. The authors report a case of gastrointestinal bleeding caused by BP involved with esophagus. A seventy year old man visited our clinic due to melena for a week. He had a quadriplegia due to fracture of cervical spine and was on therapy with corticosteroid and immunomodulatory drug for the diagnosis of BP. On endoscopic examination, multiple bullae filled with blood at lower esophagus was revealed and there was no other bleeding focus in stomach and duodenum. Medical treatment for BP with supportive care was done. The patient died due to sepsis caused by pneumonia. BP is common in elderly or poor conditioned patients. We need to consider the invasion of esophagus in case of gastrointestinal bleeding in patients with BP.

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