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J Yeungnam Med Sci > Volume 24(2 Suppl); 2007 > Article
Yeungnam University Journal of Medicine 2007;24(2 Suppl):S671-675.
DOI: https://doi.org/10.12701/yujm.2007.24.2S.S671    Published online December 31, 2007.
A Case of Esophageal Bullous Pemphigoid Manifestated by Upper Gastrointestinal Bleeding
Kyeong Ok Kim, Byung Ik Jang, Jong Ryul Eun, Tae Nyun Kim
Department of Internal Medicine, College of Medicine, Yeungnam University, Daegu, Korea
상부 위장관 출혈로 발현된 식도의 수포성 유천포창 1 예
김경옥, 장병익, 김태년, 은종렬
영남대학교 의과대학 내과학교실
Correspondence:  Byung Ik Jang, Tel: (053) 620-3830, Fax: (053) 654-8386, 
Email: jbi@med.yu.ac.kr
Abstract
Bullous pemphiogid (BP) is a chronic vesicular disorder and an autoimmune disease which has an autoantibodies to hemidesmosime in the keratinocyte. The authors report a case of gastrointestinal bleeding caused by BP involved with esophagus. A seventy year old man visited our clinic due to melena for a week. He had a quadriplegia due to fracture of cervical spine and was on therapy with corticosteroid and immunomodulatory drug for the diagnosis of BP. On endoscopic examination, multiple bullae filled with blood at lower esophagus was revealed and there was no other bleeding focus in stomach and duodenum. Medical treatment for BP with supportive care was done. The patient died due to sepsis caused by pneumonia. BP is common in elderly or poor conditioned patients. We need to consider the invasion of esophagus in case of gastrointestinal bleeding in patients with BP.
Key Words: Bullous pemphioid, Upper gastrointestinal bleeding
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