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JYMS : Journal of Yeungnam Medical Science

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HOME > J Yeungnam Med Sci > Volume 25(2); 2008 > Article
Case Report A Case of Pancreatic Acinar Cell Carcinoma.
Hwa Jung Lee, Jun Ho Ji, Seung Chan Park, Jung Chul Park, Eun Jung Choi, Hye Jin Seo, Won Sik Lee, Jung Lim Lee, Byung Jo Bae, Kyung Rak Shon, Kyung Hee Lee
Journal of Yeungnam Medical Science 2008;25(2):128-133
Published online: December 31, 2008
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1Department of Internal Medicine, Daegu Fatima Hospital, Daegu, Korea.
2Department of Surgery, Daegu Fatima Hospital, Daegu, Korea.
3Department of Pathology, Daegu Fatima Hospital, Daegu, Korea.
4Department of Internal Medicine, College of Medicine, Yeungnam University, Daegu, Korea.

Acinar cell carcinoma is a rare tumor that represents 1~2% of all pancreatic cancers. Clinical and radiologic findings are inconclusive in this disease. Acinar cell carcinoma is characterized by rapid progression and early metastasis, which lead to its poor prognosis. A 41-year-old man was admitted to our hospital for abdominal pain. Abdominal computed tomography (CT) and positron emission tomography-computed tomography (PET-CT) showed a splenic mass, which was being invaded by a pancreatic tail mass and which had increased 18F-fluorodeoxyglucose (FDG) uptake. Primary radical distal pancreatectomy and splenectomy were performed. Pathologic findings revealed an acinar cell carcinoma of the pancreas. The patient underwent a total gastrectomy three months later because of gastric recurrence. Four months later, multiple hepatic metastases were discovered, and the patient underwent a left hepatectomy. During treatment with capecitabine, there was no evidence of tumor progression for 14 months. We report a case of metastatic pancreatic acinar cell carcinoma, which did not progress for an extended period while the patient was being treated with capecitabine.

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