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- Review Combined Hepatocellular-Cholangiocarcinoma: Recent Progress in Pathology and Classification.
- Joon Hyuk Choi
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Journal of Yeungnam Medical Science 2011;28(1):1-12
DOI: https://doi.org/10.12701/yujm.2011.28.1.1
Published online: June 30, 2011
Department of Pathology, College of Medicine, Yeungnam University, Daegu, Republic of Korea. joonhyukchoi@ynu.ac.kr
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Abstract
Primary liver carcinomas have been classified into hepatocellular carcinoma, cholangiocarcinoma, and combined hepatocellular-cholangiocarcinoma (CHC). CHC is a tumor containing unequivocal, intimately mixed elements of both hepatocellular carcinoma and cholangiocarcinoma. It forms a small but significant proportion of primary liver carcinomas. The origin and pathogenesis of CHC have not been well established. According to the 2010 WHO classification, CHCs are categorized into 2 groups: the classical type and a subtype with stem cell features. This review describes recent progress in pathology and classification of CHC.
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