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J Yeungnam Med Sci > Volume 32(2); 2015 > Article
Yeungnam University Journal of Medicine 2015;32(2):111-113.
DOI:    Published online December 31, 2015.
Clear cell acanthoma on areola.
Byeong Su Kim, Yeon Woong Kim, Jin Hwa Choi, Seung Hyun Sohng, Dong Hoon Shin, Jong Soo Choi
Department of Dermatology, College of Medicine, Yeungnam University, Daegu, Korea.
Clear cell acanthoma (CCA) is an asymptomatic benign lesion of unknown origin that typically appears as a brownish, dome-shaped papule on the leg. It has an unusual clinical feature in that it appears as chronic eczema, Bowen disease, or Paget disease on the areola. Its histopathologic findings are well-demarcated psoriasiform acanthosis with pale keratinocytes (clear cells) that are rich in intracellular glycogen, which stain positively with Periodic acid-Shiff. We report herein on a young female patient with CCA on the areolar areas.
Key Words: Acanthoma, Clear cell acanthoma, Nipples
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