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Original article
- Non–coplanar whole brain radiotherapy is an effective modality for parotid sparing
- Jaehyeon Park, Jae Won Park, Ji Woon Yea
- Yeungnam Univ J Med. 2019;36(1):36-42. Published online January 3, 2019
- DOI: https://doi.org/10.12701/yujm.2019.00087
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- 9 Crossref
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Abstract
PDF - Background
The purpose of this study was to evaluate the efficacy and feasibility of non–coplanar whole brain radiotherapy (NC–WBRT) for parotid sparing.
Methods
Fifteen cases, previously treated with WBRT were selected. NC–WBRT plans were generated. The beam arrangement for the non–coplanar plans consisted of superior anterior, right, and left beams. After generation of the non–coplanar plans a field–in–field technique was applied to the bilateral parallel opposed beams in order to reduce maximum dose and increase dose homogeneity. The NC–WBRT plans were subsequently compared with the previously generated bilateral WBRT (B–WBRT) plans. A field–in–field technique was also used with the B–WBRT plans according to our departmental protocol. As per our institutional practice a total dose of 30 Gy in 10 fractions of WBRT was administered 5 days a week.
Results
The mean dose to the parotid gland for the two different plans were 16.2 Gy with B–WBRT and 13.7 Gy with NC–WBRT (p<0.05). In the NC–WBRT plan, the V5Gy, V10Gy, V15Gy, V20Gy, and V25Gy of the parotid were significantly lower (p<0.05) than those of the B–WBRT plan. The Dmax of the lens was also lower by 10% with NC–WBRT.
Conclusion
The use of NC–WBRT plans could be a simple and effective method to reduce irradiated volumes and improve the dose–volume parameters of the parotid gland. -
Citations
Citations to this article as recorded by
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Radiation Oncology.2022;[Epub] CrossRef - Setup uncertainties and appropriate setup margins in the head-tilted supine position of whole-brain radiotherapy (WBRT)
Jae Won Park, Ji Woon Yea, Jaehyeon Park, Se An Oh, Ngie Min Ung
PLOS ONE.2022; 17(8): e0271077. CrossRef - Examination of the best head tilt angle to reduce the parotid gland dose maintaining a safe level of lens dose in whole‐brain radiotherapy using the four‐field box technique
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Journal of Applied Clinical Medical Physics.2021; 22(2): 49. CrossRef - Noncoplanar Versus Coplanar Intensity-Modulated Radiation Therapy (IMRT) for Protection of the Lip and Buccal Mucosa
Zheng Lao, Fan Bi, Wenhui Fan, Xuanli Xu, Wenyong Tu, Huifeng Shi
Technology in Cancer Research & Treatment.2021;[Epub] CrossRef - Whole brain radiotherapy using four-field box technique with tilting baseplate for parotid gland sparing
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Radiation Oncology Journal.2019; 37(1): 22. CrossRef
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