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JYMS : Journal of Yeungnam Medical Science

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3 "Outcomes"
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Original article
Outcomes after repair of complete atrioventricular canal with a modified single-patch technique: a retrospective study
George Samanidis, Konstantinos Kostopanagiotou, Meletios Kanakis, Georgios Kourelis, Kyriaki Kolovou, Georgios Vagenakis, Dimitrios Bobos, Nicholas Giannopoulos
J Yeungnam Med Sci. 2023;40(2):187-192.   Published online February 1, 2023
DOI: https://doi.org/10.12701/jyms.2022.00759
  • 1,310 View
  • 53 Download
AbstractAbstract PDF
Background
This study aimed to present the short- and midterm outcomes after complete atrioventricular canal defect (CAVC) repair using a single-patch technique.
Methods
This study included 30 children who underwent surgical correction of the CAVC using a single-patch technique.
Results
The median age of the patients was 5.7 months (interquartile range [IQR], 5.0–7.5 months), and 23 patients (76.7%) had type A CAVC. Fourteen patients (46.7%) were female and 17 (56.7%) had been diagnosed with Down syndrome. The in-hospital mortality rate was 0%. No deaths were observed during a median follow-up of 4 years (IQR, 3.5–5.0 years). Patients without Down syndrome were associated with late moderate mitral regurgitation (MR) (p=0.02). Late MR less than moderate degree was observed in 96.6%, 78.5%, and 50% of patients after 2, 4, and 5 years of follow-up, respectively, while late tricuspid valve regurgitation less than moderate degree was observed in 96.7%, 85.9%, and 59.0% of patients after 2, 4, and 6 years of follow-up, respectively. After a median follow-up of 4 years, only one patient had required surgical repair of a left ventricular outflow tract obstruction, which occurred 26 months after the first operation. Multivariable logistic regression analysis adjusted for the type of CAVC, sex, Down syndrome, age, and weight revealed that the absence of Down syndrome was a risk factor for late moderate MR (MR-2) (odds ratio, 0.05; 95% confidence interval, 0.006–0.50; p=0.01).
Conclusion
A single-patch technique for CAVC surgical repair is a safe method with acceptable short- and midterm results.
Review article
Anatomical endoscopic enucleation of the prostate for bladder outlet obstruction: a narrative review
Tae Hyo Kim, Phil Hyun Song
J Yeungnam Med Sci. 2022;39(1):12-17.   Published online November 9, 2021
DOI: https://doi.org/10.12701/yujm.2021.01522
  • 3,341 View
  • 64 Download
  • 2 Web of Science
  • 2 Crossref
AbstractAbstract PDF
Anatomical endoscopic enucleation of the prostate (AEEP) differs from other endoscopic modalities for bladder outlet obstruction (BOO) because it extracts the whole benign prostatic hyperplasia component. AEEP has been launched for almost 40 years as a first-line treatment method for BOO regardless of prostate size according to several guidelines. However, it remains underperformed worldwide. In this review article, we elaborate on the advantages and disadvantages of AEEP compared to other surgical modalities for BOO to investigate its efficacy and safety as a gold standard surgical management option for males with BOO.

Citations

Citations to this article as recorded by  
  • From Consensus to Validation: A Multicenter Study for Design and Development of a Holmium Laser Enucleation of the Prostate Hydrogel Simulation Platform
    Lauren Shepard, Nathan Schuler, Gopal Narang, Shaan Setia, Akhil Das, Nicole Miller, Mitchell Humphreys, Amy Krambeck, Ahmed Ghazi
    Journal of Endourology.2024; 38(1): 60.     CrossRef
  • Robotic Assisted Simple Prostatectomy versus Holmium Laser Enucleation of the Prostate for Patients with Huge Benign Prostatic Hyperplasia
    Hye Soo Kim, Yu Seob Shin
    The World Journal of Men's Health.2023; 41(4): 753.     CrossRef
Review Article
Potential health effects of emerging environmental contaminants perfluoroalkyl compounds
Youn Ju Lee
Yeungnam Univ J Med. 2018;35(2):156-164.   Published online December 31, 2018
DOI: https://doi.org/10.12701/yujm.2018.35.2.156
  • 7,770 View
  • 101 Download
  • 7 Crossref
AbstractAbstract PDF
Environmental contaminants are one of the important causal factors for development of various human diseases. In particular, the perinatal period is highly vulnerable to environmental toxicants and resultant dysregulation of fetal development can cause detrimental health outcomes potentially affecting life-long health. Perfluoroalkyl compounds (PFCs), emerging environmental pollutants, are man-made organic molecules, which are widely used in diverse industries and consumer products. PFCs are non-degradable and bioaccumulate in the environment. Importantly, PFCs can be found in cord blood and breast milk as well as in the general population. Due to their physicochemical properties and potential toxicity, many studies have evaluated the health effects of PFCs. This review summarizes the epidemiological and experimental studies addressing the association of PFCs with neurotoxicity and immunotoxicity. While the relationships between PFC levels and changes in neural and immune health are not yet conclusive, accumulative studies provide evidence for positive associations between PFC levels and the incidence of attention deficit hyperactivity disorder and reduced immune response to vaccination both in children and adults. In conclusion, PFCs have the potential to affect human health linked with neurological disorders and immunosuppressive responses. However, our understanding of the molecular mechanism of the effects of PFCs on human health is still in its infancy. Therefore, along with efforts to develop methods to reduce exposure to PFCs, studies on the mode of action of these chemicals are required in the near future.

Citations

Citations to this article as recorded by  
  • Modifiable contributing factors to COVID-19: A comprehensive review
    Ronald Neil Kostoff, Michael Brandon Briggs, Darja Kanduc, Saikat Dewanjee, Ramesh Kandimalla, Yehuda Shoenfeld, Alan L. Porter, Aristidis Tsatsakis
    Food and Chemical Toxicology.2023; 171: 113511.     CrossRef
  • Effect of prenatal perfluoroheptanoic acid exposure on spermatogenesis in offspring mice
    Yijie Zhou, Weilian Sun, Qiuqin Tang, Yiwen Lu, Mei Li, Jing Wang, Xiumei Han, Di Wu, Wei Wu
    Ecotoxicology and Environmental Safety.2023; 260: 115072.     CrossRef
  • A Systematic Review of Contaminants of Concern in Uganda: Occurrence, Sources, Potential Risks, and Removal Strategies
    Gabson Baguma, Gadson Bamanya, Allan Gonzaga, Wycliffe Ampaire, Patrick Onen
    Pollutants.2023; 3(4): 544.     CrossRef
  • Association between maternal serum concentration of perfluoroalkyl substances (PFASs) at delivery and acute infectious diseases in infancy
    Zixia Wang, Rong Shi, Guodong Ding, Qian Yao, Chengyu Pan, Yu Gao, Ying Tian
    Chemosphere.2022; 289: 133235.     CrossRef
  • The Association between ADHD and Environmental Chemicals—A Scoping Review
    Sonja Moore, Laura Paalanen, Lisa Melymuk, Andromachi Katsonouri, Marike Kolossa-Gehring, Hanna Tolonen
    International Journal of Environmental Research and Public Health.2022; 19(5): 2849.     CrossRef
  • The Occurrence and Distributions of Per- and polyfluoroalkyl substances (PFAS) in groundwater after a PFAS leakage incident in 2018
    Zhi Yuan Yong, Ki Yong Kim, Jeong-Eun Oh
    Environmental Pollution.2020; : 115395.     CrossRef
  • Dysregulated lipid and fatty acid metabolism link perfluoroalkyl substances exposure and impaired glucose metabolism in young adults
    Zhanghua Chen, Tingyu Yang, Douglas I. Walker, Duncan C. Thomas, Chenyu Qiu, Leda Chatzi, Tanya L. Alderete, Jeniffer S. Kim, David V. Conti, Carrie V. Breton, Donghai Liang, Elizabeth R. Hauser, Dean P. Jones, Frank D. Gilliland
    Environment International.2020; 145: 106091.     CrossRef

JYMS : Journal of Yeungnam Medical Science