Journal of Yeungnam Medical Science

Original Article

Epidemiology and Clinical Features of Respiratory Viruses in Pediatric Inpatients in a Single Medical Center in Daegu from 2010 to 2012.: Eun Kyung Lee, Yun Young Lee, Kwang Hae Choi; Yeungnam Univ J Med. 2013;30(2):95-100. Published online December 31, 2013; DOI: https://doi.org/10.12701/yujm.2013.30.2.95

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BACKGROUND
This study was performed to investigate the epidemiologic and clinical features of acute respiratory viral infection in hospitalized children. METHODS: From 2010 to 2012, we tested nasopharyngeal swab specimen in 1,584 hospitalized children with multiple real-time polymerase chain reactions to identify 10 kinds of respiratory viruses (including influenza virus A, B (FluA, FluB), respiratory syncytial virus (RSV), human metapneumovirus (MPV), adenovirus (AdV), human coronavirus (CoronaV), human enterovirus (HEV), human bocavirus (HBoV), parainfluenza virus (PIV), and human rhinovirus (Rhinovirus)). We analyzed the positive rate, annual and seasonal variations, and clinical features (respiratory tract and non-respiratory tract) according to the retrospective review of medical records. RESULTS: Respiratory viruses were detected from 678 (42.8%) of 1,584 patients. The most common detected virus was RSV (35.0%), and then AdV (19.0%), HEV (18.1%). The critical period of the respiratory viral infection was during the first 12 months of a child's life. PIV increased by 8.4%, 12.1%, and 21.1% annually. Bronchiolitis was most frequently caused by RSV, and croup was frequently caused by PIV. The most common cause of meningitis was HEV. Hepatitis-associated respiratory virus was developed 111 in 678 cases. CONCLUSION: Although this study was confined to a single medical center for three years, we identified the epidemiology and clinical feature of respiratory viruses in Daegu from 2010 to 2012. Future surveillance will be necessary for annual and seasonal variations.

Citations

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Renal infarction associated with low dose intravenous immunoglobulin in a kidney transplant recipient with sepsis: a case report and literature review
Eun Woo Choi, Jun Young Do, A. Young Kim, Seok Hui Kang
BMC Nephrology.2021;[Epub] CrossRef
Correlation between Infection with Multiple Respiratory Viruses and Length of Hospital Stay in Patients from Cheonan, Korea
Jae-Sik Jeon, Jin-Wan Park, Jae Kyung Kim
The Korean Journal of Clinical Laboratory Science.2017; 49(1): 22. CrossRef
Infection Frequency and Mixed infection on Eight Viruses from Patients with Acute Respiratory Syndromes in Seoul
Heejin Ham, Jungim Jang, Sukju Jo, Younghee Oh, Sonil Pak
Journal of Bacteriology and Virology.2014; 44(3): 274. CrossRef

Review Article

Epidemiology, Risk Factors, and Pathophysiology of Osteoarthritis: Choong-ki Lee; Yeungnam Univ J Med. 2007;24(2 Suppl):S132-141. Published online December 31, 2007; DOI: https://doi.org/10.12701/yujm.2007.24.2S.S132

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Abstract PDF

Osteoarthritis (OA) is the most prevalent form of arthritis and a major cause of disability in people aged 65 and older. OA is not a single disease; rather, it is a group of overlapping yet distinct diseases with different etiologies but similar pathologic, morphologic, and clinical outcomes. OA occurs when the dynammic equilibrium between the breakdown and reapir of joint tissues is overwhelmed. Systemic and local biomechanical factors contribute to the development of the disease, with systemic factors also making the joint vulnerable and resulting in a greater impact of local joint factors. Systemic risk factors include ethnicity, gender, age, genetic factors, hormonal status, bone density, and nutritional factors. Local biomechanical factors include altered joint biomechanics, prior injuries, the effects of physical activities, sports participation, occupation, developmental abnormalities, and obesity. The normal joint is protected by biomechanical factors such as alignment and muscle strength, the lubrication provided by the synovial fluid, and the shock-absorbing function of bone and cartilage. When these functions are altered, changes occur at both the macroscopic and cellular levels, with derangements in any structure contributing to further joint destruction. 1) Further studies of both risk factor modification and cellular changes in OA will hopefully continue to enhance our understanding of this complex disease and lead to improved outcomes.

Citations

Citations to this article as recorded by

Prevalence of Osteoarthritis and Its Affecting Factors among a Korean Population Aged 50 and Over
Hye-Ryoung Kim, Eun-Jung Kim
Journal of Korean Public Health Nursing.2013; 27(1): 27. CrossRef

Original Article

Intrafamilial transmission of HCV: comparison with HBV.: Heon Ju Lee; Yeungnam Univ J Med. 1992;9(2):407-415. Published online December 31, 1992; DOI: https://doi.org/10.12701/yujm.1992.9.2.407

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Abstract PDF: Among 85 patients with anti-HCV positive chronic liver disease, only 21.2% have past history of blood transfusion and over half the cases, they do not have any suspicious risk factors for HCV infection. 3 of 85 families show anti-HCV positive family members. On the other hand, 40 of 60 patients with HBsAg positive chronic liver disease show HBsAg positive family members. In Korea, HBV is transmitted mainly through vertical and intrafamilial infection but HCV disease might be rather horizontal and sporadic than vertical. To define the evident source of infection in sporadic hepatitis C, first of all, simple test with high sensitivity and specificity for diagnosis of HCV infection would be needed.

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