Journal of Yeungnam Medical Science

Case report

Dentistry
Myxoid lipoma in the perioral mandibular region: two case reports: Jin-Ju Kwon, Sang-Hun Shin; J Yeungnam Med Sci. 2024;41(4):296-299. Published online August 2, 2024; DOI: https://doi.org/10.12701/jyms.2024.00577

3,343 View
64 Download

Abstract PDF: Lipomas are one of the most common mesenchymal tumors in the human body, exhibiting a heightened prevalence between the ages of 40 and 60 years. However, primary intraoral lipomas are rare. Myxoid lipoma, which is characterized by abundant mucoid components, is a particularly rare histological subtype of lipoma. This study presents two cases of myxoid lipoma that occurred outside the common age range for occurrence, one in the right submandibular area of a 67-year-old male and the other in the lower lip of a 3-year-old child. Through these case reports, the aim was to introduce myxoid lipoma, a rare subtype affecting facial areas, and provide a brief review to assist in the differential diagnosis, emphasizing the importance of pathological assessment. Even in age groups and anatomical locations not typically associated with lipomas, it is crucial to emphasize the necessity of careful evaluation.

Original articles

Physical therapy, Sports Therapy, and Rehabilitation
How much does clinical prediagnosis correlate with electrophysiological findings?: a retrospective study: Selda Çiftci İnceoğlu, Aylin Ayyıldız, Figen Yılmaz, Banu Kuran; J Yeungnam Med Sci. 2024;41(3):220-227. Published online July 5, 2024; DOI: https://doi.org/10.12701/jyms.2024.00381

4,291 View
72 Download
3 Web of Science
3 Crossref

Background
Electrodiagnostic testing (EDX) is important in the diagnosis and follow-up of neuropathic and myopathic diseases. This study aimed to demonstrate the compatibility between clinical prediagnosis and electrophysiological findings.
Methods
EDX results from 2004 to 2020 at the physical medicine and rehabilitation (PM&R) clinic were screened. Tests with missing data, reevaluation studies, and cases of peripheral facial paralysis were excluded. The clinical prediagnosis and EDX results were recorded, and their compatibility was evaluated.
Results
A total of 2,153 tests were included in this study. The mean age was 49.0±13.9 years and 1,533 of them (71.2%) were female. The most frequently referred clinic was the PM&R clinic (90.0%). Numbness (73.6%) was the most common complaint, followed by pain (15.3%) and weakness (13.9%). The most common prediagnosis was entrapment neuropathy (55.3%), radiculopathy (16.1%), and polyneuropathy (15.7%). Carpal tunnel syndrome was the most frequently identified type of entrapment neuropathy (78.3%). Six hundred and seventy EDX results (31.1%) were within normal limits. While the EDX results were consistent with the prediagnosis in 1,328 patients (61.7%), a pathology different from the prediagnosis was detected in 155 patients (7.2%). In the discrepancy group, the most common pathologies were entrapment neuropathy (51.7%), polyneuropathy (17.3%), and radiculopathy (15.1%). The most common neuropathy type was carpal tunnel syndrome (79.3%).
Conclusion
After adequate anamnesis and physical and neurological examinations, requesting further appropriate tests will increase the prediagnosis accuracy and prevent unnecessary expenditure of time and labor.

Citations

Citations to this article as recorded by

Optimizing Electrodiagnostic Studies: The Role of Clinical History in Improving Diagnostic Concordance—A Retrospective Study
Carlos Omar López-López, Mónica Touron De Alba, María de la Luz Montes-Castillo, Janitzia Vázquez-Mellado
Diagnostics.2025; 15(4): 436. CrossRef
Dual pathology in lateral elbow pain: the overlooked role of posterior interosseous nerve compression in refractory lateral epicondylitis
Ömer Faruk Bucak, Umit Yalcin, Cigdem Cinar, Evrim Coskun
Irish Journal of Medical Science (1971 -).2025;[Epub] CrossRef
Prognostic value of multimodal neurophysiological - ultrasound assessments in median and ulnar nerve injury repair
Xin Chen
American Journal of Translational Research.2025; 17(9): 6811. CrossRef

Pulmonary and Respiratory Medicine
Performance of the BD MAX MDR-TB assay in a clinical setting and its impact on the clinical course of patients with pulmonary tuberculosis: a retrospective before-after study: Sung Jun Ko, Kui Hyun Yoon, Sang Hee Lee; J Yeungnam Med Sci. 2024;41(2):113-119. Published online April 5, 2024; DOI: https://doi.org/10.12701/jyms.2024.00024

5,417 View
107 Download
5 Web of Science
5 Crossref

Abstract PDF

Background
Missing isoniazid (INH) resistance during tuberculosis (TB) diagnosis can worsen the outcomes of INH-resistant TB. The BD MAX MDR-TB assay (BD MAX) facilitates the rapid detection of TB and INH and rifampin (RIF) resistance; however, data related to its performance in clinical setting remain limited. Moreover, its effect on treatment outcomes has not yet been studied.
Methods
We compared the performance of BD MAX for the detection of INH/RIF resistances to that of the line probe assay (LPA) in patients with pulmonary TB (PTB), using the results of a phenotypic drug sensitivity test as a reference standard. The treatment outcomes of patients who used BD MAX were compared with those of patients who did not.
Results
Of the 83 patients included in the study, the BD MAX was used for an initial PTB diagnosis in 39 patients. The sensitivity of BD MAX for detecting PTB was 79.5%. The sensitivity and specificity of BD MAX for INH resistance were both 100%, whereas these were 50.0% and 95.8%, respectively, for RIF resistance. The sensitivity and specificity of BD MAX were comparable to those of LPA. The BD MAX group had a shorter time interval from specimen request to the initiation of anti-TB drugs (2.0 days vs. 5.5 days, p=0.001).
Conclusion
BD MAX showed comparable performance to conventional tests for detecting PTB and INH/RIF resistances. The implementation of BD MAX as a diagnostic tool for PTB resulted in a shorter turnaround time for the initiation of PTB treatment.

Citations

Citations to this article as recorded by

Diagnostic accuracy of the BD MAX MDR-TB assay on sputum and tongue swabs for Mycobacterium tuberculosis complex detection in adults under investigation for TB in South Africa
Anura David, Lyndel Singh, Manuel Pedro da Silva, Keneilwe Peloakgosi-Shikwambani, Zanele Nsingwane, Violet Molepo, Wendy Stevens, Lesley Erica Scott, Ana Cabrera
Microbiology Spectrum.2026;[Epub] CrossRef
Diagnostic Accuracy of BD MAX MDR-TB Assay Performed on Bronchoscopy Specimens in Patients with Suspected Pulmonary Tuberculosis
Sung Jun Ko, Kui Hyun Yoon
Tuberculosis and Respiratory Diseases.2025; 88(1): 150. CrossRef
The Usefulness of the BD MAX MDR-TB Molecular Test in the Rapid Diagnosis of Multidrug-Resistant Tuberculosis
Tomasz Bogiel, Edyta Dolska, Małgorzata Zimna, Kornelia Nakonowska, Dorota Krawiecka, Renata Żebracka, Maciej Pochowski, Agnieszka Krawczyk
Pathogens.2025; 14(6): 602. CrossRef
Comparative Analysis of 2 Diagnostic Devices for Detection of Mycobacterium tuberculosis and Drug Resistance in Almaty, Kazakhstan, to Determine the Optimal Diagnostic for Local Needs
Juliana G E Bartels, Nurlan Takenov, Lyailya Chingissova, Anar Rakisheva, Ainur Eleusizova, Venera Bismilda, Lyazzat Yeraliyeva, Yanis Ben Amor
Open Forum Infectious Diseases.2025;[Epub] CrossRef
Evaluating Tuberculosis Screening Tools: A Decade-Long Network Meta-Analysis of Sensitivity and Specificity with Bibliometric Insights
Diana Chusna Mufida, Muhammad Farhan Hibatulloh, Muhammad Yusuf Fadhil, Deva Fitra Firdausa Anwar, Cinday Kinanti Pramusinta, Zaskia Nafisa Salma, Annisa Eka Shabrina Salsabil, Aqilla Sakanti Chandrarini
Journal of Global Infectious Diseases.2025; 17(4): 176. CrossRef

Focused Review article

Orthopedics and Sports Medicine
State-of-the-art update for diagnosing diabetic foot osteomyelitis: a narrative review: Inha Woo, Seung Jae Cho, Chul Hyun Park; J Yeungnam Med Sci. 2023;40(4):321-327. Published online October 12, 2023; DOI: https://doi.org/10.12701/jyms.2023.00976

17,892 View
189 Download
2 Web of Science
3 Crossref

Abstract PDF

Recently, the International Working Group on the Diabetic Foot and the Infectious Diseases Society of America divided diabetic foot disease into diabetic foot infection (DFI) and diabetic foot osteomyelitis (DFO). DFI is usually diagnosed clinically, while numerous methods exist to diagnose DFO. In this narrative review, the authors aim to summarize the updated data on the diagnosis of DFO. An extensive literature search using “diabetic foot [MeSH]” and “osteomyelitis [MeSH]” or “diagnosis” was performed using PubMed and Google Scholar in July 2023. The possibility of DFO is based on inflammatory clinical signs, including the probe-to-bone (PTB) test. Elevated inflammatory biochemical markers, especially erythrocyte sedimentation rate, are beneficial. Distinguishing abnormal findings of plain radiographs is also a first-line approach. Moreover, sophisticated modalities, including magnetic resonance imaging and nuclear medicine imaging, are helpful if doubt remains after a first-line diagnosis. Transcutaneous bone biopsy, which does not pass through the wound, is necessary to avoid contaminating the sample. This review focuses on the current diagnostic techniques for DFOs with an emphasis on the updates. To obtain the correct therapeutic results, selecting a proper option is necessary. Based on these numerous diagnosis modalities and indications, the proper choice of diagnostic tool can have favorable treatment outcomes.

Citations

Citations to this article as recorded by

Evaluasi Temuan Radiologi Foto Polos Pedis dextra pada Pasien dengan Osteomielitis di Instalasi Radiologi Rumah Sakit Siloam Sriwijaya Palembang
Danda Wibowo, Harry Wahyudhy, Zanariah
JURNAL LENTERA ILMIAH KESEHATAN.2026; 4(1): 8. CrossRef
Deep learning-enhanced MRI for diabetic foot tarsal bone lesions and insulin injection behavior analysis
Haidong Ye, Fang Yao
Journal of Radiation Research and Applied Sciences.2025; 18(2): 101493. CrossRef
Unveiling the challenges of diabetic foot infections: diagnosis, pathogenesis, treatment, and rehabilitation
Chul Hyun Park
Journal of Yeungnam Medical Science.2023; 40(4): 319. CrossRef

Original articles

Gastroenterology and Hepatology
Diagnostic value of serum procalcitonin and C-reactive protein in discriminating between bacterial and nonbacterial colitis: a retrospective study: Jae Yong Lee, So Yeon Lee, Yoo Jin Lee, Jin Wook Lee, Jeong Seok Kim, Ju Yup Lee, Byoung Kuk Jang, Woo Jin Chung, Kwang Bum Cho, Jae Seok Hwang; J Yeungnam Med Sci. 2023;40(4):388-393. Published online April 3, 2023; DOI: https://doi.org/10.12701/jyms.2023.00059

9,207 View
87 Download
1 Web of Science
1 Crossref

Abstract PDF

Background
Differentiating between bacterial and nonbacterial colitis remains a challenge. We aimed to evaluate the value of serum procalcitonin (PCT) and C-reactive protein (CRP) in differentiating between bacterial and nonbacterial colitis.
Methods
Adult patients with three or more episodes of watery diarrhea and colitis symptoms within 14 days of a hospital visit were eligible for this study. The patients’ stool pathogen polymerase chain reaction (PCR) testing results, serum PCT levels, and serum CRP levels were analyzed retrospectively. Patients were divided into bacterial and nonbacterial colitis groups according to their PCR. The laboratory data were compared between the two groups. The area under the receiver operating characteristic curve (AUC) was used to evaluate diagnostic accuracy.
Results
In total, 636 patients were included; 186 in the bacterial colitis group and 450 in the nonbacterial colitis group. In the bacterial colitis group, Clostridium perfringens was the commonest pathogen (n=70), followed by Clostridium difficile toxin B (n=60). The AUC for PCT and CRP was 0.557 and 0.567, respectively, indicating poor discrimination. The sensitivity and specificity for diagnosing bacterial colitis were 54.8% and 52.6% for PCT, and 52.2% and 54.2% for CRP, respectively. Combining PCT and CRP measurements did not increase the discrimination performance (AUC, 0.522; 95% confidence interval, 0.474–0.571).
Conclusion
Neither PCT nor CRP helped discriminate bacterial colitis from nonbacterial colitis.

Citations

Citations to this article as recorded by

Procalcitonin and C-Reactive Protein as Diagnostic Biomarkers for Bacterial Gastroenteritis: A Retrospective Analysis
Hyunseok Cho, Jung Ho Lee, Sung Chul Park, Sung Joon Lee, Hee-Jeong Youk, Seung-Joo Nam, Jin Myung Park, Tae Suk Kim, Ji Hyun Kim, San Ha Kim, Sang Hoon Lee
Journal of Clinical Medicine.2025; 14(7): 2135. CrossRef

Obstetrics, Gynecology, and Reproductive Medicine
Rates and subsequent clinical course of fetal congenital anomalies detected by prenatal targeted ultrasonography of 137 cases over 5 years in a single institute: a retrospective observational study: Haewon Choi, Hyo-Shin Kim, Joon Sakong; J Yeungnam Med Sci. 2023;40(3):268-275. Published online November 2, 2022; DOI: https://doi.org/10.12701/jyms.2022.00514

5,592 View
78 Download
3 Web of Science
2 Crossref

Abstract PDF

Background
With the establishment of international guidelines and changes in insurance policies in Korea, the role of targeted ultrasonography has increased. This study aimed to identify the rates and clinical course of anomalies detected using prenatal targeted ultrasonography.
Methods
This study was a retrospective analysis of all pregnancies with targeted ultrasonography performed in a single secondary medical center over 5 years.
Results
Fetal anomalies were detected by targeted ultrasonography in 137 of the 8,147 cases (1.7%). The rates of anomalies were significantly higher in female fetuses (2.0% vs. 1.3%). In cases of female fetuses, the rate of anomalies was significantly higher in the advanced maternal age group (2.4% vs. 1.2%). In cases of male fetuses, the rate of anomalies was significantly higher in nulliparous (2.4% vs. 1.5%) and twin (5.7% vs. 1.9%) pregnancies. Pulmonary anomalies were significantly more common in the multiparity group (17.6% vs. 5.8%). Among the 137 cases, 17.5% terminated the pregnancy, 16.8% were diagnosed as normal after birth, and 42.3% were diagnosed with anomalies after birth or required follow-up.
Conclusion
Through the first study on the rates and clinical course of anomalies detected by targeted ultrasonography at a single secondary center in Korea, we found that artificial abortions were performed at a high rate, even for relatively mild anomalies or anomalies with good prognosis. We suggest the necessity of a nationwide study to establish clinical guidelines based on actual incidences or prognoses.

Citations

Citations to this article as recorded by

Application of AI to Ultrasonographic Images to Aid the Clinical Care of Pregnant Women With Pre-eclampsia in Uganda: A Protocol for a Pilot Study
Mugyenyi R Godfrey, Fredrick Atwiine, Esther C Atukunda, Leo Anthony Celi, Rogers Mwavu, Fred Kaggwa, Jessica E Haberer, William Wasswa
Cureus.2026;[Epub] CrossRef
Clinical profile of Korean children with spina bifida: a single-center prospective cohort study
Hyeseon Yun, Seung Hyeon Yang, Hooyun Lee, Sang Woon Kim, Yong Seung Lee, Yoonhye Ji, Jieun Park, Jeong-Eun Ji, Eun Kyoung Choi
BMC Pediatrics.2024;[Epub] CrossRef

Review article

Radiology, Radiotherapy & Diagnostic Imaging
Avulsion injuries: an update on radiologic findings: Changwon Choi, Sun Joo Lee, Hye Jung Choo, In Sook Lee, Sung Kwan Kim; Yeungnam Univ J Med. 2021;38(4):289-307. Published online August 13, 2021; DOI: https://doi.org/10.12701/yujm.2021.01102

26,455 View
368 Download
13 Crossref

Abstract PDF

Avulsion injuries result from the application of a tensile force to a musculoskeletal unit or ligament. Although injuries tend to occur more commonly in skeletally immature populations due to the weakness of their apophysis, adults may also be subject to avulsion fractures, particularly those with osteoporotic bones. The most common sites of avulsion injuries in adolescents and children are apophyses of the pelvis and knee. In adults, avulsion injuries commonly occur within the tendon due to underlying degeneration or tendinosis. However, any location can be involved in avulsion injuries. Radiography is the first imaging modality to diagnose avulsion injury, although advanced imaging modalities are occasionally required to identify subtle lesions or to fully delineate the extent of the injury. Ultrasonography has a high spatial resolution with a dynamic assessment potential and allows the comparison of a bone avulsion with the opposite side. Computed tomography is more sensitive for depicting a tiny osseous fragment located adjacent to the expected attachment site of a ligament, tendon, or capsule. Moreover, magnetic resonance imaging is the best imaging modality for the evaluation of soft tissue abnormalities, especially the affected muscles, tendons, and ligaments. Acute avulsion injuries usually manifest as avulsed bone fragments. In contrast, chronic injuries can easily mimic other disease processes, such as infections or neoplasms. Therefore, recognizing the vulnerable sites and characteristic imaging features of avulsion fractures would be helpful in ensuring accurate diagnosis and appropriate patient management. To this end, familiarity with musculoskeletal anatomy and mechanism of injury is necessary.

Citations

Citations to this article as recorded by

Multimodality Imaging in Musculoskeletal Trauma: A Comprehensive Review
Madhavi Chamarthi, K.J.S.S. Raghu Teja, Anil Kumar Kallepalli, Rajesh Allu, Sonica Sharma
Apollo Medicine.2026; 23(1): 63. CrossRef
Imaging in Sports Injuries
Anuja Dubey, Chapala Shashank, Rizwana Farween Rajmohamed, Ankit Shah, Gaurav Kant Sharma
Apollo Medicine.2026; 23(1): 82. CrossRef
Diagnostic performance of dual-energy Rho/Z CT and cinematic rendering in Achilles tendon rupture: a prospective multi-reader study
Qizheng Wang, Suwei Liu, Yupeng Zhu, Xiaoxi Ji, Yan Zhang, Qiang Zhao, Aihui Di, Yang Lv, Ning Lang
Skeletal Radiology.2026;[Epub] CrossRef
Diversity and antibiotic susceptibility profiles of bacterial isolates from wound infections in patients at the surgical unit of Kisii teaching and referral hospital, Kenya
Samson Onsando, Wycliffe Masanta, Andrew Nyerere, Moses Njire, Gervason Moriasi, Mabel Kamweli Aworh
PLOS One.2025; 20(6): e0326048. CrossRef
Iliac Epiphyseal Avulsion Repair Using a Suture Bridge and Lag Screw Construct
Nicholas D. Cominos, Saif L. Juma, Jamil Haddad, Annamarie Pantuso, Lafi S. Khalil
Arthroscopy Techniques.2025; 14(10): 103803. CrossRef
Pediatric knee avulsion fractures: A systematic review of injury patterns, treatment strategies, and outcomes
Yasmin Youssef, Lukas F. Heilmann, Nils Mühlenfeld, Bastian Mester, Johannes Weber, Kai Fehske, Orla Klatte, Doreen Schneidmüller, Peter Strohm, Ralf Henkelmann
European Journal of Trauma and Emergency Surgery.2025;[Epub] CrossRef
Common Mistakes in Bone and Soft Tissue Tumors
Matthieu Van Herck, Filip M. Vanhoenacker, Koenraad Verstraete
Seminars in Musculoskeletal Radiology.2025; 29(05): 776. CrossRef
Surgical management of posterior ligament complex stripping in an adolescent spinal flexion distraction injury: A case report and literature review
Dong-Ju Lim
International Journal of Surgery Case Reports.2024; 114: 109195. CrossRef
Ischial Tuberosity Avulsion Fracture Mimicking Calcified Mass on Plain Films: A Case Report
Mason A Williams, Lena Naffaa
Cureus.2024;[Epub] CrossRef
ESR essentials: MRI of the knee—practice recommendations by ESSR
Anagha P. Parkar, Miraude E. A. P. M. Adriaensen
European Radiology.2024; 34(10): 6590. CrossRef
Subtle Avulsion of the Anterior Superior Iliac Spine With Incidental Finding of Coxa Profunda
Josh Landers, Evan Rosenzweig
JOSPT Cases.2024; 4(3): 139. CrossRef
Adolescent Male With Sudden, Severe Onset Right Groin Pain
Michael Hofer, Carl A. Germann, Peter Croft, Timothy Sweeney
Annals of Emergency Medicine.2024; 84(4): 447. CrossRef
Isolated fracture of the lesser tuberosity of the humerus – a rare injury that requires surgical treatment
Miodrag Glisic, Vladan Stevanovic, Aleksandar Jevtic, Uros Jovicevic, Ivan Jankovic
Vojnosanitetski pregled.2023; 80(3): 279. CrossRef

Original article

Emergency and Critical Care Medicine
Clinical investigation on acute pyelonephritis without pyuria: a retrospective observational study: Hyung Keun Song, Dong Hyuk Shin, Ji Ung Na, Sang Kuk Han, Pil Cho Choi, Jang Hee Lee; J Yeungnam Med Sci. 2022;39(1):39-45. Published online August 11, 2021; DOI: https://doi.org/10.12701/yujm.2021.01207

15,827 View
348 Download
2 Web of Science
1 Crossref

Abstract PDF

Background
The current guidelines for the diagnosis of acute pyelonephritis (APN) recommend that APN be diagnosed based on the clinical features and the presence of pyuria. However, we observed that some of the patients who are diagnosed with APN do not have characteristic clinical features or pyuria at the initial examination. We performed this study to investigate the characteristics of APN without pyuria.
Methods
A retrospective, cross-sectional study was conducted on 391 patients diagnosed with APN based on clinical and radiologic findings, between 2015 and 2019. The clinical features, laboratory results, and computed tomography (CT) findings were compared between patients with normal white blood cell (WBC) counts and those with abnormal WBC counts (WBC of 0–5/high power field [HPF] vs. >5/HPF) in urine.
Results
More than 50% of patients with APN had no typical urinary tract symptoms and one-third of them had no costovertebral angle (CVA) tenderness. Eighty-eight patients (22.5%) had normal WBC counts (0–5/HPF) on urine microscopy. There was a negative correlation between pyuria (WBC of >5/HPF) and previous antibiotic use (odds ratio, 0.249; 95% confidence interval, 0.140–0.441; p<0.001), and the probability of pyuria was reduced by 75.1% in patients who took antibiotics before visiting the emergency room.
Conclusion
The diagnosis of APN should not be overlooked even if there are no typical clinical features, or urine microscopic examination is normal. If a patient has already taken antibiotics at the time of diagnosis, imaging studies such as CT should be performed more actively, regardless of the urinalysis results.

Citations

Citations to this article as recorded by

Clinical Characteristics, Microbiological Spectrum, Biomarkers, and Imaging Insights in Acute Pyelonephritis and Its Complicated Forms—A Systematic Review
Marius-Costin Chițu, Teodor Salmen, Paula-Roxana Răducanu, Carmen-Marina Pălimariu, Bianca-Margareta Salmen, Anca Pantea Stoian, Viorel Jinga, Dan Liviu Dorel Mischianu
Medicina.2026; 62(1): 222. CrossRef

Review article

Otorhinolaryngology
Current diagnosis and treatment of vestibular neuritis: a narrative review: Chang Hoon Bae, Hyung Gyun Na, Yoon Seok Choi; J Yeungnam Med Sci. 2022;39(2):81-88. Published online August 9, 2021; DOI: https://doi.org/10.12701/yujm.2021.01228

65,535 View
852 Download
22 Web of Science
36 Crossref

Abstract PDF

Vertigo is the sensation of self-motion of the head or body when no self-motion is occurring or the sensation of distorted self-motion during an otherwise normal head movement. Representative peripheral vertigo disorders include benign paroxysmal positional vertigo, Ménière disease, and vestibular neuritis. Vestibular neuritis, also known as vestibular neuronitis, is the third most common peripheral vestibular disorder after benign paroxysmal positional vertigo and Ménière disease. The cause of vestibular neuritis remains unclear. However, a viral infection of the vestibular nerve or ischemia of the anterior vestibular artery is known to cause vestibular neuritis. In addition, recent studies on immune-mediated mechanisms as the cause of vestibular neuritis have been reported. The characteristic clinical features of vestibular neuritis are abrupt true-whirling vertigo lasting for more than 24 hours, and no presence of cochlear symptoms and other neurological symptoms and signs. To accurately diagnose vestibular neuritis, various diagnostic tests such as the head impulse test, bithermal caloric test, and vestibular-evoked myogenic potential test are conducted. Various treatments for vestibular neuritis have been reported, which are largely divided into symptomatic therapy, specific drug therapy, and vestibular rehabilitation therapy. Symptomatic therapies include generalized supportive care and administration of vestibular suppressants and antiemetics. Specific drug therapies include steroid therapy, antiviral therapy, and vasodilator therapy. Vestibular rehabilitation therapies include generalized vestibular and customized vestibular exercises.

Citations

Citations to this article as recorded by

Repurposing Renin–Angiotensin System Drugs for the Treatment of Audiovestibular Disorders
Grant Podhajsky, Kiran S. Marla, Alec P. Marticoff, Kenny Nguyen, Tanner Kempton, Sepehr Salehpour, Caden Duffy, Douglas M. Bennion
Journal of Clinical Medicine.2026; 15(2): 743. CrossRef
Immune alterations in vestibular neuritis: a retrospective database pilot study on T and B lymphocyte profiles and cytokine levels
Zhaohui Song, Yuchuan Ding, Wesley Kohls, Jing Feng, Huimin Fan, Pan Gu, Xiaokun Geng
Frontiers in Neurology.2026;[Epub] CrossRef
The diagnostic and prognostic role of the pan-immune-inflammation value in vestibular neuritis
Fatma Atalay
Anatolian Current Medical Journal.2026; 8(1): 130. CrossRef
THE EFFECTIVENESS OF THE EPLEY MANEUVER FOR BENIGN PAROXYSMAL POSITIONAL VERTIGO: A META-ANALYSIS
Khalid AlYahya
BULLETIN OF STOMATOLOGY AND MAXILLOFACIAL SURGERY.2026;[Epub] CrossRef
Vestibular Disorders
Prabhat K. Pokhrel, Rose Hall, Melanie Pendergrass, Jasmine Kaur
Primary Care: Clinics in Office Practice.2025; 52(1): 15. CrossRef
Altered amplitude of low-frequency fluctuation and functional connectivity in patients with acute unilateral vestibulopathy: a resting-state fMRI study
Zhengwei Chen, Liangqun Rong, Lijie Xiao, Jie Rao, Haiyan Liu, Tengfei Liu, Fei Chen, Jun Zhang, Lu Wang, Xi Li, Xiue Wei
Frontiers in Neurology.2025;[Epub] CrossRef
Management Strategies of Vestibular Neuritis:- A Review
Santosh Kumar Swain, Chappity Preetam
Medical Journal of Dr. D.Y. Patil Vidyapeeth.2025; 18(1): 5. CrossRef
Bibliometric analysis of global research trends in vestibular neuritis (1980–2024)
Mehmet Akif Dündar, Ahmet Avcı, Müşerref Arık, Ahmet Tayfur Akcan, Hasan Kazak
European Archives of Oto-Rhino-Laryngology.2025; 282(4): 1879. CrossRef
Critical analysis and management of benign paroxysmal positional vertigo in Ayurveda: A case report
Mohammed Irfan, B. S. Naveen, B. Geetha Kumari, Ajoy Viswam, Krishnan N. Namboodiri, Laxmi M. Naik
Journal of Indian System of Medicine.2025; 12(4): 184. CrossRef
Developing a Diagnostic Algorithm for Identifying Vestibular Neuronitis in Acute Dizziness: An Overview of Epidemiology, Pathogenesis, and Evidence-Based Guidelines for Diagnostic Approaches
Petros V Vlastarakos, Giorgos Sideris, Eleni Vasileiou, Efterpi Michailidou, Nikolaos Papadimitriou, Dimitrios Palantzas, Konstantina Melissourgou, Evangelos Panagoulis, Panagiotis P Gogoulos, Thomas Nikolopoulos
Cureus.2025;[Epub] CrossRef
Negative Video Head Impulse Test in Acute Vestibular Syndrome Does Not Exclude Vestibular Neuritis: Insights and Challenges in Diagnosis
Pavol Skacik, Stefan Sivak, Egon Kurca
Clinical Case Reports.2025;[Epub] CrossRef
Nationwide trends in steroid therapy for vestibular neuritis: insights from South Korea’s health insurance review and assessment data
Chul Young Yoon, Tae Hoon Kong, Young Joon Seo, Ji-Yun Park
Frontiers in Neurology.2025;[Epub] CrossRef
Nationwide resource utilization of dizziness/vertigo presentations to the ED
David O’Neil Danis, Matthew Kovoor, Emily K. Gjini, Jonathon S. Sillman, Kathryn Y. Noonan
Eye & ENT Research.2025; 2(2): 116. CrossRef
Increased 25-hydroxycholesterol as an indicator for patients with vestibular neuritis
Xuhua Song, Jingwei Liang, Congzhe Tian
Frontiers in Neurology.2025;[Epub] CrossRef
Efficacy of vestibular tests for differential diagnosis of acute vestibular disorders: a cross-sectional study
Sharda Sarda, C. S. Vanaja, R Chetana, Priscilla Joshi, S Gorthi
The Egyptian Journal of Otolaryngology.2025;[Epub] CrossRef
Stroke – Screening Tools and Mimics
Alfredo Manuel da Silva Leal
medtigo Journal of Medicine.2025; 1(1): 1. CrossRef
Prevalence and Impact of Vertigo and Dizziness in Adults: A Hospital-Based Evaluation
Amir Hamza, . Ikramullah, Mohammad Azam, Abdul Wahid, Abdul Bari
Pakistan Journal of Health Sciences.2025; : 21. CrossRef
Acute Bilateral Vestibular Neuropathy During Myocardial Infarction: A Case Report
Francesco Comacchio, Elia Biancoli, Elisabetta Poletto, Barbara Bellemo, Paola Magnavita
Journal of Otorhinolaryngology, Hearing and Balance Medicine.2025; 6(2): 15. CrossRef
Vestibular Evoked Myogenic Potentials to Diagnose Vestibular Neuritis: A Scoping Review
Diego Piatti, Laura Casagrande Conti, Gianluca Paolocci, Iole Indovina, Marco Tramontano, Leonardo Manzari
The Laryngoscope.2025;[Epub] CrossRef
Weather and Seasonality Associations With Vestibular Neuritis
Athanasios Vlachodimitropoulos, Gerasimos Danielides, Theodoros Stathas, Georgios Batsaouras, Vasileios Papanikos, Christine Dafni, Spyridon Lygeros
Cureus.2025;[Epub] CrossRef
Vestibular function is associated with immune inflammatory response
Zhaohui Song, Yuchuan Ding, Nathan Sim, Ho Jun Yun, Jing Feng, Pan Gu, Xiaokun Geng
Reviews in the Neurosciences.2024; 35(3): 293. CrossRef
Prevalence of Scarpa’s ganglion enhancement on high-resolution MRI imaging
Clayton Siminski, John C Benson, Matthew L Carlson, John I Lane
The Neuroradiology Journal.2024; 37(3): 332. CrossRef
Vestibular rehabilitation for peripheral vestibular hypofunction: an interdisciplinary consensus
N.L. Kunelskay, G.E. Ivanova, E.V. Baybakova, A.L. Guseva, V.A. Parfenov, M.V. Zamergrad, O.V. Zaitseva, O.A. Melnikov, A.A. Shmonin, M.N. Maltseva
Russian Bulletin of Otorhinolaryngology.2024; 89(1): 52. CrossRef
A Review of Calcitonin Gene-Related Peptide and Its Implications for Vestibular Disorders
Richard Baron, Kristen K. Steenerson
Current Treatment Options in Neurology.2024; 26(6): 203. CrossRef
Evolution of Hyperventilation-Induced Nystagmus in Acute Unilateral Vestibulopathy—Interpretative Model and Etiopathogenetic Hypotheses
Francesco Frati, Alessandra D’Orazio, Valeria Gambacorta, Giacomo Ciacca, Giampietro Ricci, Mario Faralli
Audiology Research.2024; 14(3): 442. CrossRef
Evaluating the impact of COVID-19 on vertigo and hearing impairment: A post-recovery analysis
Sarah Alshehri, Khalid A. Alahmari
Medicine.2024; 103(27): e38819. CrossRef
Does dimenhydrinate delay recovery of vestibular ocular reflex in acute unilateral vestibulopathy? A retrospective comparative study
Minah Shin, Chae-Young Kim, Ji Eun Choi, Jae Yun Jung, Min Young Lee
Research in Vestibular Science.2024; 23(3): 89. CrossRef
Vestibular Dysfunction in Patients With Sickle Cell Disease: A Systematic Review
Jonathan Laredo, Sofia Torres-Small, Lin Wu, Tomoko Makishima, Celine Richard
Otology & Neurotology.2024; 45(10): 1098. CrossRef
The Inner Ear: A Primer for Radiologists, Part 1: Anatomy, Physiology, and Intrinsic Abnormalities of the Otic Capsule
E. Zamora, C. Zamora
Neurographics.2024; 14(4): 267. CrossRef
Vertigo in the Setting of COVID-19 Infection: A Case Report
Sanjana Devaragudi, Mohit Gupta
Cureus.2023;[Epub] CrossRef
Hospital Admission Profile Related to Inner Ear Diseases in England and Wales
Esra’ O. Taybeh, Abdallah Y. Naser
Healthcare.2023; 11(10): 1457. CrossRef
Symptom of vertigo and dizziness in patients with COVID-19
E. V. Isakova
Russian neurological journal.2023; 28(4): 5. CrossRef
VESTIBULAR NEURONITIS: A CLINICAL EXAMPLE OF THE COURSE OF THE DISEASE USING BIOFEEDBACK (BOS)
Geraskina M.M., Razzhivina K.S., Ustinov S.A.
"Medical & pharmaceutical journal "Pulse".2023; : 30. CrossRef
Acute vestibular neuritis: A rare complication after the adenoviral vector-based COVID-19 vaccine
Hamze Shahali, Ramin Hamidi Farahani, Parham Hazrati, Ebrahim Hazrati
Journal of NeuroVirology.2022; 28(4-6): 609. CrossRef
A Holistic Approach to a Dizzy Patient: A Practical Update
Ioannis Koukoulithras, Gianna Drousia, Spyridon Kolokotsios, Minas Plexousakis, Alexandra Stamouli, Charis Roussos, Eleana Xanthi
Cureus.2022;[Epub] CrossRef
Identification of hub genes and pathophysiological mechanism related to acute unilateral vestibulopathy by integrated bioinformatics analysis
Yajing Cheng, Jianrong Zheng, Ying Zhan, Cong Liu, Bihua Lu, Jun Hu
Frontiers in Neurology.2022;[Epub] CrossRef

Case report

Obstetrics, Gynecology, and Reproductive Medicine
The diagnosis of an imperforate anus in female fetuses: Hyun Mi Kim, Hyun-Hwa Cha, Jong In Kim, Won Joon Seong, Sook-Hyun Park, Mi Ju Kim; Yeungnam Univ J Med. 2021;38(3):240-244. Published online October 7, 2020; DOI: https://doi.org/10.12701/yujm.2020.00507

14,855 View
249 Download
6 Crossref

Abstract PDF

Imperforate anus is an anomaly caused by a defect in the development of the hindgut during early pregnancy. It is a relatively common congenital malformation and is more common in males. Although there are cases of a solitary imperforate anus, the condition is more commonly found as a part of a wider spectrum of other congenital anomalies. Although urgent reconstructive anorectal surgery is not necessary, immediate evaluation is important and urgent decompressive surgery may be required. Moreover, as there are often other anomalies that can affect management, prenatal diagnosis can help in optimizing perinatal care and prepare parents through prenatal counseling. In the past, imperforate anus was diagnosed by prenatal ultrasonography based on indirect signs such as bowel dilatation or intraluminal calcified meconium. Currently, it is diagnosed by directly checking the perineum with prenatal ultrasonography. Despite advances in ultrasound technology, accurate prenatal diagnosis is impossible in most cases and imperforate anus is detected after birth. Here, we present two cases of imperforate anus in female fetuses that were not diagnosed prenatally.

Citations

Citations to this article as recorded by

New ultrasound features in diagnosing fetal anal atresia: a multicenter prospective cohort study
Haiyan Kuang, Hui Cao, Sheng Wang, Yingchun Luo, Yang Gao, Lingyu Yan, Junyi Yan, Yulin Peng
Scientific Reports.2024;[Epub] CrossRef
Ultrasonography guided puncture and dilatation in membranous rectal atresia
Cunera M.C. de Beaufort, Joep P.M. Derikx, Simon G.F. Robben, Rick R. van Rijn, Ramon R. Gorter, L.W. Ernest van Heurn
Journal of Pediatric Surgery Case Reports.2023; 89: 102564. CrossRef
Radiology findings of Down syndrome: a literature review
Jacobus Jeno Wibisono, Carissa Faustina, Maria Georgina Wibisono, Jeanne Leman, Ratna Sutanto
Chinese Journal of Academic Radiology.2023; 6(4): 133. CrossRef
Аноректальні аномалії розвитку
Ольга Антонюк, Василь Пикалюк, Олександр Слободян, Альона Романюк, Людмила Шварц
Notes in Current Biology.2023;[Epub] CrossRef
Anorectoplasty and external sphincteroplasty via inverted V-shaped incision on the perineum for the treatment of imperforate anus with rectal fistula to navicular fossa: Report of 26 cases
Da Ma, Yi Wang, Ying-Song Liu
Asian Journal of Surgery.2022; 45(6): 1313. CrossRef
Challenges in prenatal diagnosis of foetal anorectal malformation and hydrocolpos – Case report
Muhammad Alamsyah Aziz, Fatima Zahra, Cut ZB Razianti, Nuniek Kharismawati, Tjut Sutjighassani, Nadia Larastri Almira, Kevin Dominique Tjandraprawira
Annals of Medicine & Surgery.2022;[Epub] CrossRef

Focused Review article

Pulmonary and Respiratory Medicine
Diagnosis and treatment of multidrug-resistant tuberculosis: Jong Geol Jang, Jin Hong Chung; Yeungnam Univ J Med. 2020;37(4):277-285. Published online September 4, 2020; DOI: https://doi.org/10.12701/yujm.2020.00626

29,049 View
701 Download
101 Crossref

Abstract PDF

Tuberculosis (TB) is still a major health problem worldwide. Especially, multidrug-resistant TB (MDR-TB), which is defined as TB that shows resistance to both isoniazid and rifampicin, is a barrier in the treatment of TB. Globally, approximately 3.4% of new TB patients and 20% of the patients with a history of previous treatment for TB were diagnosed with MDR-TB. The treatment of MDR-TB requires medications for a long duration (up to 20–24 months) with less effective and toxic second-line drugs and has unfavorable outcomes. However, treatment outcomes are expected to improve due to the introduction of a new agent (bedaquiline), repurposed drugs (linezolid, clofazimine, and cycloserine), and technological advancement in rapid drug sensitivity testing. The World Health Organization (WHO) released a rapid communication in 2018, followed by consolidated guidelines for the treatment of MDR-TB in 2019 based on clinical trials and an individual patient data meta-analysis. In these guidelines, the WHO suggested reclassification of second-line anti-TB drugs and recommended oral treatment regimens that included the new and repurposed agents. The aims of this article are to review the treatment strategies of MDR-TB based on the 2019 WHO guidelines regarding the management of MDR-TB and the diagnostic techniques for detecting resistance, including phenotypic and molecular drug sensitivity tests.

Citations

Citations to this article as recorded by

Mitoxantrone elicits ROS-dependent elimination of dysfunctional mitochondria through mitophagy to control viability of intracellular mycobacteria in human macrophages
Mousumi Das, Dev Kiran Nayak, Salina Patel, Ashish Kumar, Mustafeez Ali Quaderi, Pramathesh Kumar Dandsena, Lincoln Naik, Abtar Mishra, Amit Mishra, Ramandeep Singh, Sujit Kumar Bhutia, Assirbad Behura, Rohan Dhiman
Biochemical Pharmacology.2026; 243: 117512. CrossRef
Methods to Improve Confidence in the Accuracy of Molecular Testing for Multidrug-Resistant Tuberculosis
Denise M O’Sullivan, Gerwyn M Jones, Manca Zolnir-Dovc, Richard Phillips, Rejoice Arthur, Bariki Mtafya, Daniel Adon Mapamba, Daniela Maria Cirillo, Ewa Augustynowicz-Kopeć, Mei Mei Ho, Belinda Dagg, Sven O Friedrich, Francesca Colavita, Antonella Vulcano
Clinical Chemistry.2026;[Epub] CrossRef
A Case of Multidrug-Resistant Tuberculosis in an Active Duty Military Health Care Worker
Amanda E Saunders, Kevin M Shanahan, John W Downs
Military Medicine.2025; 190(1-2): e448. CrossRef
Latest Progress on Tuberculosis and HIV Co‐Infection: A Closer Look at People of Different Ages
Anna Yusuf Aliyu, Oluwatoyin A. Adeleke
Advanced Therapeutics.2025;[Epub] CrossRef
Advancing against drug-resistant tuberculosis: an extensive review, novel strategies and patent landscape
Meghana N. Patel, Archita J. Patel, Manish N. Nandpal, Manan A. Raval, Ravish J. Patel, Amit A. Patel, Keshav Raj Paudel, Philip M. Hansbro, Sachin Kumar Singh, Gaurav Gupta, Kamal Dua, Samir G. Patel
Naunyn-Schmiedeberg's Archives of Pharmacology.2025; 398(3): 2127. CrossRef
The Role of Nanomaterials in Diagnosis and Targeted Drug Delivery
Ekhlakh Veg, Kulsum Hashmi, Saman Raza, Seema Joshi, Abdul Rahman Khan, Tahmeena Khan
Chemistry & Biodiversity.2025;[Epub] CrossRef
Utility of Artificial Intelligence in Antibiotic Development: Accelerating Discovery in the Age of Resistance
Esteban Zavaleta-Monestel, Carolina Rojas-Chinchilla, Jeimy Campos-Hernández, Ernesto Martínez-Vargas
Cureus.2025;[Epub] CrossRef
Characteristics and treatment outcomes of adolescents and young adults living with HIV with drug-resistant tuberculosis co-infection in Uganda: a retrospective cohort study
Ivaan Pitua, Marvin Kirya, Denis Kiberu, Shivan Nabaasa, Amelia Margaret Namiiro, Michael Collins Segawa, Patrick Semakula, Sarah Maria Najjuka, Joseph Baruch Baluku, Ronald Olum
Therapeutic Advances in Infectious Disease.2025;[Epub] CrossRef
Functional Prognosis of Spinal Cord Injury Due to Spinal Tuberculosis
Farida Arisanti, Tertianto Prabowo, Putri Endyana, Apichana Kovindha
OBM Neurobiology.2025; 09(01): 1. CrossRef
Artemisia Afra and Artemisia Annua against pulmonary tuberculosis
William Wang, Pascal Gisenya
Pharmacy & Pharmacology International Journal.2025; 13(1): 21. CrossRef
Dual Burden of MDR‐TB and COVID‐19 in a Previously Treated Tuberculosis Case: Diagnostic and Therapeutic Dilemmas
Gudisa Bereda
Clinical Case Reports.2025;[Epub] CrossRef
Truenat MTB assays for pulmonary tuberculosis and rifampicin resistance in adults and adolescents
Leeberk Raja Inbaraj, Jefferson Daniel, Mukesh Kumar Sathya Narayanan, Vignes Anand Srinivasalu, Adhin Bhaskar, Katie Scandrett, Priya Rajendran, Richard Kirubakaran, Hemant D Shewade, Muniyandi Malaisamy, Chandrasekaran Padmapriyadarsini, Yemisi Takwoing
Cochrane Database of Systematic Reviews.2025;[Epub] CrossRef
Innovative Strategies for Combating Multidrug-Resistant Tuberculosis: Advances in Drug Delivery Systems and Treatment
Omobolanle A. Omoteso, Adewale O. Fadaka, Roderick B. Walker, Sandile M. Khamanga
Microorganisms.2025; 13(4): 722. CrossRef
N-Acetylcysteine to Reduce Kidney and Liver Injury Associated with Drug-Resistant Tuberculosis Treatment
Idu Meadows, Happiness Mvungi, Kassim Salim, Oscar Kaswaga, Peter Mbelele, Alphonce Liyoyo, Hadija Semvua, Athumani Ngoma, Scott K. Heysell, Stellah G. Mpagama
Pharmaceutics.2025; 17(4): 516. CrossRef
Head and Neck Tuberculosis: A Rare Diagnosis and the Role of Surgical Biopsy and Histopathological Evaluation in Extrapulmonary Disease
Carmen Aurelia Mogoantă, Andrei Osman, Alina-Maria Georgescu, Alexandra Maria Mitroi, Constantin Ioan Busuioc, Ionuţ Tănase, Ramona Cioboată, Ilona Mihaela Liliac, Ovidiu Lucian Cimpeanu, Mircea Sorin Ciolofan
Pathogens.2025; 14(5): 479. CrossRef
Coexisting Lung Cancer and Pulmonary Tuberculosis: A Comprehensive Review From Incidence to Management
Wendi Zhou, Hongxu Lu, Jiamin Lin, Jialou Zhu, Jizhen Liang, Yalin Xie, Jinxing Hu, Ning Su
Cancer Reports.2025;[Epub] CrossRef
Green synthesis of Cu nanoparticles using Biarum chaduchrum leaf extract and their efficacy against multi-drug-resistant Mycobacterium tuberculosis
Xiaoguo Zhang, Zaiqin Ling
Chemical Papers.2025; 79(8): 5009. CrossRef
Magnetic nanoparticles as a promising antimicrobial agent for combating multidrug resistant bacteria: a review
Ahmed M. El-Khawaga, Maurizio Orlandini, Luisa Raucci, Karim Elmaghraby
Discover Applied Sciences.2025;[Epub] CrossRef
Education on Assistance for Drug-Resistant TB Patients Since Diagnosis to Community TB Cadres Through Cadre Training Activities in Kediri City in 2025
Nurita Nilasari Bunga Kharisma Arifiana Putri, Heny Kristanto, Yunarsih, Sucipto, Puguh Santoso, Betristasia Puspitasari
Journal of Community Service for Health.2025; 6(1): 026. CrossRef
CRISPR-Cas9-based electrochemical biosensor for the detection of katG gene mutations in isoniazid-resistant tuberculosis
Dika Apriliana Wulandari, Muhammad Ihda Hamlu Liwaissunati Zein, Salma Nur Zakiyyah, Safri Ishmayana, Mehmet Ozsoz, Yeni Wahyuni Hartati, Irkham
ADMET and DMPK.2025; : 2766. CrossRef
Characterizing Musculoskeletal and Neurological Toxicities Associated With the BPaLM Regimen: A Clinical Evaluation of Arthralgia and Peripheral Neuropathy in Patients With Multidrug-Resistant Tuberculosis (MDR-TB)
Zahir Khan, Gohar Ali, Rumman ., Ashraf ., Akmal Naveed, Shahid Salam, Ubaid Ullah, Ahmad Ismail, Afrasyab Altaf
Cureus.2025;[Epub] CrossRef
A Call to Action: Empowering Pharmacists in Drug-Resistant Tuberculosis Management
Mohammed Alfaqeeh, Prayudi Santoso, Jan-Willem Alffenaar, Ivan Pradipta
Journal of Multidisciplinary Healthcare.2025; Volume 18: 3531. CrossRef
Role of Transcription Factor NR1H3 in the Pathogenesis of Tuberculosis
Anju Kumari, Rajwinder Kaur
Biology Bulletin Reviews.2025; 15(4): 475. CrossRef
Pre-treatment loss to follow-up and associated factors among drug-resistant tuberculosis patients diagnosed in Wakiso district, central Uganda
James Arinaitwe, James Muleme, Perez N. Ochanda, Rebecca Nuwematsiko, Samson Omongot, Barnabas Bakamutumaho, Esther Buregyeya
BMC Infectious Diseases.2025;[Epub] CrossRef
Drug selection based on pan-genomics genetic features of Mycobacterium tuberculosis
Xiangcheng Sun, Panpan Xu, Yun Shi, Ning Wang, Yan Li
Frontiers in Microbiology.2025;[Epub] CrossRef
Adverse drug reactions to the nine-month all-oral and 18-month regimens for multidrug-resistant tuberculosis in Indonesia
Nina Mariana, Anggi Gayatri, Indah Suci Widyahening, Budiman Bela, Neni Sawitri, Soedarsono Soedarsono, Erni Juwita Nelwan, Purwantyastuti Ascobat
International Journal of Risk & Safety in Medicine.2025;[Epub] CrossRef
All‐Oral Shorter Treatment Regimens for Multidrug‐ and Rifampicin‐Resistant Tuberculosis: Evaluating Their Effectiveness, Safety, and Impact on the Quality of Life of Patients in Lao PDR
Vibol Iem, Sakhone Suthepmany, Vongkham Inthavong, Anousone Sisouvanh, Khamloun Choumlivong, Kyung Hyun Oh, Philipp du Cros, Fatimata Bintou Sall, Corinne S. Merle, Jacques Sebert, Donekham Inthavong
Tropical Medicine & International Health.2025; 30(12): 1340. CrossRef
Diagnostic assistance method for RR-TB/MDR-TB patients under treatment based on CNN-LSTM
Jie Li, Wenqing Wu, Zhixiong Fang, Pinxiang Fu, Hua Huang, Yanhong Zhou, Liang Yu, He Huang, Tao Wang, Qilong Zhang
Scientific Reports.2025;[Epub] CrossRef
Label-free electrochemical-based biosensor for gene-phosphatidylinositol mannosides detection in urine for the determination of multidrug-resistant tuberculosis
Dinesh R Rotake, Jitendra B Zalke, Arpita Parakh, Shubham C Anjankar, Shiv Govind Singh, Ranjana Singh
Nanotechnology.2025; 36(41): 415501. CrossRef
Immune profiles of immune checkpoint molecules on peripheral T cells in multidrug resistant-tuberculosis
Xiaoxu Yang, Lan Yao, Xu-wei Gui, Yangdian Lai, Ping Ji, Ying Wang, Yingying Chen, Wei Sha
International Journal of Infectious Diseases.2025; 161: 108085. CrossRef
Magnitude of poor multidrug-resistant tuberculosis treatment outcome among multidrug-resistant tuberculous patients at tertiary hospital, South West Ethiopia
Gemechu Gelana Ararame, Hailegabreil Nardos
Annals of Clinical Microbiology and Antimicrobials.2025;[Epub] CrossRef
Predicting multi-drug resistant tuberculosis using machine learning on genomic and clinical data
Komal Saxena, S Shyni Carmel Mary, Prolay Ghosh, Chinnem Rama Mohan, Mohd Naved, Mukesh Madanan
Indian Journal of Tuberculosis.2025; 72: S99. CrossRef
Comparative genomic analysis of drug-resistant and drug-sensitive tuberculosis strains and their impact on cough severity
Malik Olatunde Oduoye, Hiba Zafar, Umer Wamiq, Suheera Afzoon, Hafsa Shuja, Adeniji Oluwapelumi Wumi, Abdulmumeen Ibrahim Opeyemi
Mycobacteria.2025;[Epub] CrossRef
Beyond Hotspot Mutations: Diagnostic Relevance of High Frequency, Low Frequency, and Disputed rpoB Variants in Rifampicin-Resistant Mycobacterium tuberculosis
Siti Soidah, Toto Subroto, Irvan Faizal, Muhammad Yusuf
Pathogens.2025; 15(1): 16. CrossRef
Optimal accompanying diagnosis design through external validation of population pharmacokinetic models for moxifloxacin in tuberculosis patients
Hyunjung Lee, Woojin Jung, Min Jung Chang, Soyoung Lee, Jung-woo Chae, Radojka M. Savic, Hwi-yeol Yun
BMC Infectious Diseases.2025;[Epub] CrossRef
The Relationship Between Family Social Support and Medication Adherence Among Tuberculosis Patients in Community Health Centers of Sleman Regency
Kusbandia M.Pharm, Anna Wahyuni Widayanti, Chairun Wiedyaningsih
Malaysian Journal of Medicine and Health Sciences.2025;[Epub] CrossRef
Computational insights into potential marine natural products as selective inhibitors of Mycobacterium tuberculosis InhA: A structure-based virtual screening study
Manikandan Jayaraman, Vijayakumar Gosu, Rajalakshmi Kumar, Jeyakanthan Jeyaraman
Computational Biology and Chemistry.2024; 108: 107991. CrossRef
Targeting of essential mycobacterial replication enzyme DnaG primase revealed Mitoxantrone and Vapreotide as novel mycobacterial growth inhibitors**
Waseem Ali, Salma Jamal, Rishabh Gangwar, Faraz Ahmed, Rahul Sharma, Meetu Agarwal, Javaid Ahmad Sheikh, Abhinav Grover, Sonam Grover
Molecular Informatics.2024;[Epub] CrossRef
A Comprehensive Review on Long vs. Short Regimens in Multidrug-Resistant Tuberculosis (MDR-TB) Under Programmatic Management of Drug-Resistant Tuberculosis (PMDT)
Ashwin Karnan, Ulhas Jadhav, Babaji Ghewade, Anjana Ledwani, Poorna Shivashankar
Cureus.2024;[Epub] CrossRef
Design, synthesis and biological evaluation of novel pyrido-[2,3-d]-pyrimidin-2-amine analogues as antimycobacterial agents
Boddupalli Venkata Siva Kumar, Yogesh Mahadu Khetmalis, Kosana Sai Chaitanya, Ala Chandu, Gauri Shetye, Rui Ma, Sankaranarayanan Murugesan, Scott G. Franzblau, Kondapalli Venkata Gowri Chandra Sekhar
Journal of Molecular Structure.2024; 1303: 137600. CrossRef
Direct TAMRA-dUTP labeling of M. tuberculosis genes using loop-mediated isothermal amplification (LAMP)
Basma Altattan, Jasmin Ullrich, Emily Mattig, Aline Poppe, Renata Martins, Frank F. Bier
Scientific Reports.2024;[Epub] CrossRef
Antimicrobial peptides as new-generation antibiotics against Mycobacterium
Parisa Eslami, Adnan Khosravi
Journal of Preventive, Diagnostic and Treatment Strategies in Medicine.2024; 3(1): 6. CrossRef
Factors Associated with Non-Adherence to Treatment Among Migrants with MDR-TB in Wuhan, China: A Cross-Sectional Study
Kunhe Lin, Li Xiang
Risk Management and Healthcare Policy.2024; Volume 17: 727. CrossRef
Development of a self-microemulsifying drug delivery system to deliver delamanid via a pressurized metered dose inhaler for treatment of multi-drug resistant pulmonary tuberculosis
Himanshu Paliwal, Titpawan Nakpheng, Pijush Kumar Paul, K. Prem Ananth, Teerapol Srichana
International Journal of Pharmaceutics.2024; 655: 124031. CrossRef
Drug Targets, Current and Future Therapeutics for the Treatment of Multi Drug Resistant Tuberculosis with their Clinical Applications: A Critical Review
Deepshikha Singh, Vikram Singh, Subhankar P. Mandal, Karen Dsouza, B.R. Prashantha Kumar, Sheshagiri R. Dixit
Current Drug Therapy.2024; 19(3): 317. CrossRef
Epidemiology and Management of Infections in Liver Transplant Recipients
Waseem Amjad, Syed Hamaad Rahman, Thomas D. Schiano, Syed-Mohammed Jafri
Surgical Infections.2024; 25(4): 272. CrossRef
Survival Probability in Multidrug Resistant Pulmonary Tuberculosis Patients in a South Indian Region
Thungathurthi Smitha, Pantham Sunitha, Orsu Prabhakar, Sindgi Vasudeva Murthy
Hospital Pharmacy.2024; 59(4): 427. CrossRef
Tuberculosis: Implications for Dentistry
Xue-Mei Chong, Lucy McClean, Paddy McMaster
Dental Update.2024; 51(4): 258. CrossRef
The mechanisms and clinical potential of collateral sensitivity in Mycobacterium tuberculosis: A literature review
Muhammad Zain Raza, Hafiz Muhammad Ehsan Arshad, Musab Maqsood, Muhammad Hashim Faisal
The Microbe.2024; 3: 100086. CrossRef
Confronting Tuberculosis: A Synthetic Quinoline-Isonicotinic Acid Hydrazide Hybrid Compound as a Potent Lead Molecule Against Mycobacterium tuberculosis
Govinda Raju Vadankula, Vipul V. Nilkanth, Arshad Rizvi, Sriram Yandrapally, Anushka Agarwal, Hepshibha Chirra, Rashmita Biswas, Mohammed Arifuddin, Vijay Nema, Alvala Mallika, Shekhar C. Mande, Sharmistha Banerjee
ACS Infectious Diseases.2024; 10(6): 2288. CrossRef
Advancements in Artificial Intelligence for the Diagnosis of Multidrug Resistance and Extensively Drug-Resistant Tuberculosis: A Comprehensive Review
Shanmuga Priya K, Anbumaran Parivakkam mani, Geethalakshmi S, Sankalp Yadav
Cureus.2024;[Epub] CrossRef
Opinion review of drug resistant tuberculosis in West Africa: tackling the challenges for effective control
Isaac Darko Otchere, Adwoa Asante-Poku, Kodjo Francis Akpadja, Awa Ba Diallo, Adama Sanou, Prince Asare, Stephen Osei-Wusu, Nneka Onyejepu, Bassirou Diarra, Yaotsè Anoumou Dagnra, Aderemi Kehinde, Martin Antonio, Dorothy Yeboah-Manu
Frontiers in Public Health.2024;[Epub] CrossRef
Advanced integrative molecular platform for high-throughput screening of drug-resistant tuberculosis
Minal Dakhave, Trupti Rale, Harshada Suryawanshi, Nikita Patil, Abhijeet Suryawanshi, Raju Kumar, Shruti Gadekar, Payal Bhatnagar, Amrita Khaire, Gautam Wankhede
Diagnostic Microbiology and Infectious Disease.2024; 109(4): 116373. CrossRef
The use of additive technologies to increase adherence to treatment, increase the efficiency of chemotherapy and correction of indicators of anxiety and depression among patients with destructive pulmonary tuberculosis
Alexey G. Naumov, Alexander S. Shprykov, Marina A. Dolgova, Natalia V. Fomina
Consilium Medicum.2024; 26(3): 199. CrossRef
Prevalence and patterns of drug-resistant Mycobacterium tuberculosis in newly diagnosed patients in China: A systematic review and meta-analysis
Cong Jin, Yuting Wu, Jiangpo Chen, Jing Liu, Hongwei Zhang, Qingzeng Qian, Tieliang Pang
Journal of Global Antimicrobial Resistance.2024; 38: 292. CrossRef
Enhanced detection of rifampicin and isoniazid resistance in mycobacterium tuberculosis using AuNP-qPCR: a rapid and accurate method
Mouhai He
American Journal of Translational Research.2024; 16(6): 2310. CrossRef
Identification of tuberculosis inhibitors through QSAR-based virtual screening and molecular dynamics simulation of novel pyrimidine derivatives
Abdelmadjid Guendouzi, Lotfi Belkhiri, Yaakoub Kebila, Brahim Houari, Abdelhamid Djekoune, Abdou Boucekkine, Jehad Zuhair Tayyeb, Shopnil Akash, Magda H. Abdellattif, Abdelkrim Guendouzi
Journal of the Indian Chemical Society.2024; 101(10): 101298. CrossRef
Immunoinformatics and structural aided approach to develop multi-epitope based subunit vaccine against Mycobacterium tuberculosis
Guneswar Sethi, Rinku Polachirakkal Varghese, Avinash Kant Lakra, Subhashree Subhasmita Nayak, Ramadas Krishna, Jeong Ho Hwang
Scientific Reports.2024;[Epub] CrossRef
Optimization of Polylactide-Co-Glycolide-Rifampicin Nanoparticle Synthesis, In Vitro Study of Mucoadhesion and Drug Release
Nazgul A. Yessentayeva, Aldana R. Galiyeva, Arailym T. Daribay, Daniyar T. Sadyrbekov, Rouslan I. Moustafine, Yerkeblan M. Tazhbayev
Polymers.2024; 16(17): 2466. CrossRef
A Narrative Review of Bedaquiline and Delamanid: New Arsenals Against Multidrug‐Resistant and Extensively Drug‐Resistant Mycobacterium tuberculosis
Nazanin Ahmad Khosravi, Mehrandokht Sirous, Azar Dokht Khosravi, Morteza Saki
Journal of Clinical Laboratory Analysis.2024;[Epub] CrossRef
A review of molecular investigations on traditional Chinese medicinal plant-based therapies in multidrug-resistant tuberculosis
Robin Raj, Arpan Kumar Tripathi, P. Saranya, Jaskiran kaur, Rashmi Saxena Pal, Kuldeep Singh, Divya Jain, MVNL Chaitanya, Shivendra Kumar
Pharmacological Research - Modern Chinese Medicine.2024; 13: 100521. CrossRef
Multidrug-resistant tuberculosis treatment outcomes and associated factors at Yirgalem General Hospital, Sidama Region, South Ethiopia: a retrospective cohort study
Assefa Hamato Kebede, Hassen Mamo
BMC Pulmonary Medicine.2024;[Epub] CrossRef
Prediction of the Potential of Benzoxazinone, 2-phenyl-4H-benzo[1,3]oxazin-4-one, and 2-[2-(4-methoxyphenyl)vinyl]-3,1-benzoxazin-4-one as New Anti-Tuberculosis
Kholis Amalia Nofianti, Luqmanul Hakim, Suzana, Farida Ifadotunikamah
Berkala Ilmiah Kimia Farmasi.2024; 11(1): 26. CrossRef
Comparison of Anxiety Levels in MDR-TB Patients with Individual and Short-term Regimens at Dr. Soebandi Regional General Hospital, Jember, Indonesia
Muhammad Rifqy Alvy Widodo, Ida Srisurani Wiji Astuti, Inke Kusumastuti, Angga Mardro Raharjo, Supangat Supangat, Justina Evy Tyaswati, Noor Fadzilah binti Zulkifli
Jurnal Respirasi.2024; 10(2): 107. CrossRef
Novel Prodrug Strategies for the Treatment of Tuberculosis
Christine G. Kim, Jiney Jose, Michael P. Hay, Peter J. Choi
Chemistry – An Asian Journal.2024;[Epub] CrossRef
Advances in the Synthesis and Biological Applications of Enoxacin-Based Compounds
Garba Suleiman, Nabil El Brahmi, Gérald Guillaumet, Saïd El Kazzouli
Biomolecules.2024; 14(11): 1419. CrossRef
Treatment outcomes in patients with multi-drug resistant tuberculosis
Unyime Israel Eshiet, Mary Richard Akpan, Idongesit Linus Jackson, Aniekpeno Sunday Uduak, Dighenyong Samuel Udiminue
Medicine India.2024; 3: 77. CrossRef
Molecular genetic characteristics of Mycobacterium tuberculosis strains isolated from newly identified tuberculosis patients in the Republic of Azerbaijan
Nuria Salimova, Dmitry Gryadunov
Bulletin of the Academy of Sciences of Moldova. Medical Sciences.2024; 79(2): 30. CrossRef
Synthesis and Structure–Activity Relationship of 2,6-Disubstituted Thiosemicarbazone Derivatives of Pyridine as Potential Antituberculosis Agents
Dagmara Ziembicka, Katarzyna Gobis, Małgorzata Szczesio, Andrzej Olczak, Ewa Augustynowicz-Kopeć, Agnieszka Głogowska, Izabela Korona-Głowniak, Krzysztof Bojanowski
Materials.2023; 16(1): 448. CrossRef
Multidrug-Resistant TB (MDR-TB) and Extensively Drug-Resistant TB (XDR-TB) Among Children: Where We Stand Now
Kona Chowdhury, Rahnuma Ahmad, Susmita Sinha, Siddhartha Dutta, Mainul Haque
Cureus.2023;[Epub] CrossRef
Anxiety and depression level of patients with multidrug-resistant tuberculosis (MDR-TB) in two hospitals in Banten province, Indonesia
Tirta Darmawan Susanto, Allen Widysanto, Darien Alfa Cipta, Arron Tanara, Ghivarell Rizkie Wirawan, Adeline Bercadina Kosim, Christabella Maria Djoni, Ervinna Tantri, Chandni Kumar, Chelsie Angelius
Dialogues in Health.2023; 2: 100115. CrossRef
Characteristics of Previous Tuberculosis Treatment History in Patients with Treatment Failure and the Impact on Acquired Drug-Resistant Tuberculosis
Soedarsono Soedarsono, Ni Made Mertaniasih, Tutik Kusmiati, Ariani Permatasari, Wiwik Kurnia Ilahi, Amelia Tantri Anggraeni
Antibiotics.2023; 12(3): 598. CrossRef
Evolution of tuberculosis diagnostics: From molecular strategies to nanodiagnostics
Srestha Mukherjee, Summaya Perveen, Anjali Negi, Rashmi Sharma
Tuberculosis.2023; 140: 102340. CrossRef
Assessment of the Diagnostic Utility of GeneXpert Mycobacterium tuberculosis/Rifampicin (MTB/RIF) Assay in the Suspected Cases of Tuberculous Meningitis
Sakshi Patel, Malti Dadheech, Anand K Maurya, Jitendra Singh, Shashank Purwar, Nirendra Rai, Radha Sarawagi, Ankur Joshi, Sagar Khadanga
Cureus.2023;[Epub] CrossRef
Tandem LC-MS Identification of Antitubercular Compounds in Zones of Growth Inhibition Produced by South African Filamentous Actinobacteria
Daniel J. Watson, Lubbe Wiesner, Tlhalefo Matimela, Denzil Beukes, Paul R. Meyers
Molecules.2023; 28(11): 4276. CrossRef
Drug-Resistant Tuberculosis Stigma Among HealthCare Workers Toward the Development of a Stigma-Reduction Strategy: A Scoping Review
Lolita Liboon Aranas, Khorshed Alam, Prajwal Gyawali, Rashidul Mahumud Alam
INQUIRY: The Journal of Health Care Organization, Provision, and Financing.2023;[Epub] CrossRef
Quality Mindset: The Missing Ingredient in Tuberculosis Care and Control in Togo
Kossivi Agbélénko Afanvi, Mohammed Fall Dogo, Koffi Atsu Aziagbé, Komi Séraphin Adjoh, Koumavi Kristoli Didier Ekouévi
European Journal of Theoretical and Applied Sciences.2023; 1(4): 36. CrossRef
Machine Learning of the Whole Genome Sequence of Mycobacterium tuberculosis: A Scoping PRISMA-Based Review
Ricardo Perea-Jacobo, Guillermo René Paredes-Gutiérrez, Miguel Ángel Guerrero-Chevannier, Dora-Luz Flores, Raquel Muñiz-Salazar
Microorganisms.2023; 11(8): 1872. CrossRef
Cotreatment With Clofazimine and Rapamycin Eliminates Drug-Resistant Tuberculosis by Inducing Polyfunctional Central Memory T-Cell Responses
Dhiraj Kumar Singh, Ashima Bhaskar, Isha Pahuja, Aishwarya Shaji, Barnani Moitra, Yufang Shi, Ved Prakash Dwivedi, Gobardhan Das
The Journal of Infectious Diseases.2023; 228(9): 1166. CrossRef
Treatment of drug-resistant tuberculosis in children and young adolescents in Brazil
Fernanda Bruzadelli Paulino da Costa, Thaís Zamboni Berra, Jaqueline Garcia de Almeida Ballestero, Patricia Bartholomay Oliveira, Daniele Maria Pelissari, Yan Mathias Alves, Antônio Carlos Vieira Ramos, Juliana Queiroz Rocha de Paiva, Titilade Kehinde Aya
Journal of Clinical Tuberculosis and Other Mycobacterial Diseases.2023; 33: 100388. CrossRef
Tackling Drug-Resistant Tuberculosis: New Challenges from the Old Pathogen Mycobacterium tuberculosis
Giuseppe Mancuso, Angelina Midiri, Silvia De Gaetano, Elena Ponzo, Carmelo Biondo
Microorganisms.2023; 11(9): 2277. CrossRef
Drug-resistant Monoarticular Wrist Joint Tuberculosis in Renal Transplant Recipient with Literature Review
Jasmine Sethi, Vignesh Subramani, Rajender Kumar, Shivakumar Patil, Ashish Sharma
Indian Journal of Transplantation.2023; 17(3): 371. CrossRef
Predictive capabilities of baseline radiological findings for early and late disease outcomes within sensitive and multi-drug resistant tuberculosis cases
Gabriel Rosenfeld, Andrei Gabrielian, Darrell Hurt, Alex Rosenthal
European Journal of Radiology Open.2023; 11: 100518. CrossRef
Nanocarriers in Tuberculosis Treatment: Challenges and Delivery Strategies
Mahesh Kumar, Tarun Virmani, Girish Kumar, Rohitas Deshmukh, Ashwani Sharma, Sofia Duarte, Pedro Brandão, Pedro Fonte
Pharmaceuticals.2023; 16(10): 1360. CrossRef
A systematic review and meta-analysis on the correlation between HIV infection and multidrug-resistance tuberculosis
Yulong Song, Qian Jin, Jihai Qiu, Dan Ye
Heliyon.2023; 9(11): e21956. CrossRef
Current Insights into Diagnosing and Treating Neurotuberculosis in Adults
Sofiati Dian, Ahmad Rizal Ganiem, Lindsey HM te Brake, Arjan van Laarhoven
CNS Drugs.2023; 37(11): 957. CrossRef
Economic burden of multidrug-resistant tuberculosis on patients and households: a global systematic review and meta-analysis
Temesgen Yihunie Akalu, Archie C. A. Clements, Haileab Fekadu Wolde, Kefyalew Addis Alene
Scientific Reports.2023;[Epub] CrossRef
Nano vs Resistant Tuberculosis: Taking the Lung Route
Deepika Sharma, Pooja, Sunita Nirban, Smriti Ojha, Tarun Kumar, Neha Jain, Najwa Mohamad, Pradeep Kumar, Manisha Pandey
AAPS PharmSciTech.2023;[Epub] CrossRef
Multi-Drug Resistance Tuberculosis (MDR-TB) Challenges in India: A Review
Deepak Vishwakarma, Abhay Gaidhane, Sweta Sahu, Ashwini S Rathod
Cureus.2023;[Epub] CrossRef
Multidrug-resistant Tuberculosis and its Implication with COVID-19
Jasmine Arya, Sweety Dahiya, Anil Kumar Chhillar
Coronaviruses.2023;[Epub] CrossRef
Tuberculosis drug discovery: Progression and future interventions in the wake of emerging resistance
Summaya Perveen, Diksha Kumari, Kuljit Singh, Rashmi Sharma
European Journal of Medicinal Chemistry.2022; 229: 114066. CrossRef
Abdominal Tuberculosis Mimicking Ovarian Cancer: A Case Report and Review of the Literature
Ikhwan Rinaldi, Abdul Muthalib, Djaja Gosal, Teguh Wijayadi, Barlian Sutedja, Tjondro Setiawan, Andika Gunawan, Nelly Susanto, Lingga Magdalena, Diah Rini Handjari, Fetisari Kurniawan, Aisyah Rifani, Kevin Winston
International Medical Case Reports Journal.2022; Volume 15: 169. CrossRef
Pediatric Tuberculosis Management: A Global Challenge or Breakthrough?
Lehlogonolo N. F. Maphalle, Bozena B. Michniak-Kohn, Modupe O. Ogunrombi, Oluwatoyin A. Adeleke
Children.2022; 9(8): 1120. CrossRef
Various approaches to improving adherence of patients with tuberculosis. Prospects for the use of additive technologies in TB practice
A. G. Naumov, A. S. Shprykov
PULMONOLOGIYA.2022; 34(1): 80. CrossRef
Antimicrobial Peptides as Potential Anti-Tubercular Leads: A Concise Review
Gabriel S. Oliveira, Raquel P. Costa, Paula Gomes, Maria Salomé Gomes, Tânia Silva, Cátia Teixeira
Pharmaceuticals.2021; 14(4): 323. CrossRef
Treatment of Human Babesiosis: Then and Now
Isaline Renard, Choukri Ben Mamoun
Pathogens.2021; 10(9): 1120. CrossRef
Novel mutations detected from drug resistant Mycobacterium tuberculosis isolated from North East of Thailand
Ei Phoo Thwe, Wises Namwat, Porntip Pinlaor, Kulrattana Rueangsak, Arunnee Sangka
World Journal of Microbiology and Biotechnology.2021;[Epub] CrossRef
On the Mechanism of Development of Autoimmune Diseases Following Exposure to Inactivated Mycobacterium tuberculosis
SV Skupnevskiy, GM Trukhina, EG Pukhaeva, AK Badtiev, FK Rurua, FE Batagova, ZhG Farnieva
ЗДОРОВЬЕ НАСЕЛЕНИЯ И СРЕДА ОБИТАНИЯ - ЗНиСО / PUBLIC HEALTH AND LIFE ENVIRONMENT.2021; : 76. CrossRef
Oral regimen for multi-drug-resistant TB can promote patient-centred and community-based treatment
Suman Saurabh, Pankaj Bhardwaj
Journal of Family Medicine and Primary Care.2021; 10(12): 4607. CrossRef
Adverse effects induced by second-line antituberculosis drugs: an update based on last WHO treatment recommendations for drug-resistant tuberculosis
Ionela-Alina Grosu-Creangă, Antigona Carmen Trofor, Radu Adrian Crișan-Dabija, Daniela Robu-Popa, Cristina Mihaela Ghiciuc, Elena Cătălina Lupușoru
Pneumologia.2021; 70(3): 117. CrossRef
Advances in the science and treatment of respiratory diseases
Jin Hong Chung
Yeungnam University Journal of Medicine.2020; 37(4): 251. CrossRef

Review article

Gastroenterology and Hepatology
Drug-induced liver injury: Jeong Ill Suh; Yeungnam Univ J Med. 2020;37(1):2-12. Published online August 27, 2019; DOI: https://doi.org/10.12701/yujm.2019.00297

25,151 View
455 Download
27 Crossref

Abstract PDF

Drug-induced liver injury (DILI), including herbal and dietary supplement hepatotoxicity, is often passed lightly; however, it can lead to the requirement of a liver transplant or may even cause death because of liver failure. Recently, the American College of Gastroenterology, Chinese Society of Hepatology and European Association for the Study of the Liver guidelines for the diagnosis and treatment of DILI have been established, and they will be helpful for guiding clinical treatment decisions. Roussel Uclaf Causality Assessment Method scoring is the most commonly used method to diagnose DILI; however, it has some limitations, such as poor validity and reproducibility. Recently, studies on new biomarkers have been actively carried out, which will help diagnose DILI and predict the prognosis of DILI. It is expected that the development of new therapies such as autophagy inducers and various other technologies of the fourth industrial revolution will be applicable to DILI research.

Citations

Citations to this article as recorded by

In vitro and in silico evaluation of synthetic compounds derived from bi-triazoles against asexual and sexual forms of Plasmodium falciparum
Leandro do Nascimento Martinez, Minelly Azevedo da Silva, Saara Neri Fialho, Marcinete Latorre Almeida, Amália dos Santos Ferreira, Aurileya de Jesus Gouveia, Welington da Silva Paula do Nascimento, Ana Paula de Azevedo dos Santos, Norton Rubens Diunior L
Malaria Journal.2025;[Epub] CrossRef
Exploring drug-induced liver injury: comprehensive insights into mechanisms and management of hepatotoxic agents
Ahmed K. Saleh, Thanaa A. El-Masry, Aya H. El-Kadem, Nada A. Ashour, Nageh A. El-Mahdy
Future Journal of Pharmaceutical Sciences.2025;[Epub] CrossRef
A case report of liver failure caused by Tetrastigma hemsleyanum Diels et Gilg: A rare case report and literature review
Yan Liu, Xia Zhou, Qiong-Fen Wang, Ming-Wei Liu
Medicine.2025; 104(13): e42059. CrossRef
FAERS based disproportionality analysis and network pharmacology investigation of taxanes associated drug induced liver injury
Yijie Cheng, Yuxin Yang, Yan Su, Ruihuan Chen, Da Qian, Jingyuan Xu
Scientific Reports.2025;[Epub] CrossRef
Risks of hepatotoxicities during the intensive phase of tuberculosis treatment: A hospital-based case control study
Khanaphan Kemmarak, Bhunyabhadh Chaimay, Somkiattiyos Woradet
Asian Pacific Journal of Tropical Medicine.2025; 18(10): 451. CrossRef
Tocotrienol as a Potential Treatment for Drug-Induced Liver Injury
Nur Syazana Syahira Mohd Norman, Muhammad Ridhuan Al Rasyid Bin Ruslan, Juliana Abd Hamid, Fadhlullah Zuhair Japar Sidik, Nur Azlina Mohd Fahami, Azman Abdullah
International Journal of Pharmacology.2025;[Epub] CrossRef
Drug-Induced Liver Injury Due to Doxycycline: A Case Report and Review of Literature
Nikola Nikolajevic, Milan Nikolajevic, Ivana Pantic, Bojan Korica, Magdalena Kotseva, Tamara Alempijevic, Dorde Jevtic, Cristian I Madrid, Igor Dumic
Cureus.2024;[Epub] CrossRef
Drug-resistant epilepsy and its selected complications in children
Magdalena Knopek, Joanna Iwanicka, Grzegorz Boryczka
Annales Academiae Medicae Silesiensis.2024; 78: 127. CrossRef
An Open-Label Extension Study Assessing the Long-Term Safety and Efficacy of Viloxazine Extended-Release Capsules in Adults with Attention-Deficit/Hyperactivity Disorder
Ann Childress, Andrew J. Cutler, Lenard A. Adler, Nicholas Fry, Kobby Asubonteng, Zulane Maldonado-Cruz, Andrea Formella, Jonathan Rubin
CNS Drugs.2024; 38(11): 891. CrossRef
Severe liver injury induced by minocycline in hepatitis B patient: a Case Report
Ran Wang, Yun Li, Xue Xia
Frontiers in Pharmacology.2024;[Epub] CrossRef
Liver Injury in Favipiravir-Treated COVID-19 Patients: Retrospective Single-Center Cohort Study
Amal Oweid Almutairi, Mahmoud Zaki El-Readi, Mohammad Althubiti, Yosra Zakariyya Alhindi, Nahla Ayoub, Abdullah R. Alzahrani, Saeed S. Al-Ghamdi, Safaa Yehia Eid
Tropical Medicine and Infectious Disease.2023; 8(2): 129. CrossRef
Hepatotoxic Components Effect of Chebulae Fructus and Associated Molecular Mechanism by Integrated Transcriptome and Molecular Docking
Liwen Ai, Fan Yang, Wanjun Hu, Liyang Guo, Weixue Liu, Xuexue Xue, Lulu Li, Zunlai Sheng
Molecules.2023; 28(8): 3427. CrossRef
Systematic Review of Safety of Selective Androgen Receptor Modulators in Healthy Adults: Implications for Recreational Users
Jonathan D. Vignali, Kevin C. Pak, Holly R. Beverley, Jesse P. DeLuca, John W. Downs, Adrian T. Kress, Brett W. Sadowski, Daniel J. Selig
Journal of Xenobiotics.2023; 13(2): 218. CrossRef
Antitubercular drugs induced liver injury: an updated insight into molecular mechanisms
Devaraj Ezhilarasan
Drug Metabolism Reviews.2023; 55(3): 239. CrossRef
Advances in Idiosyncratic Drug-Induced Liver Injury Issues: New Clinical and Mechanistic Analysis Due to Roussel Uclaf Causality Assessment Method Use
Rolf Teschke, Gaby Danan
International Journal of Molecular Sciences.2023; 24(13): 10855. CrossRef
Application of artificial intelligence and machine learning in early detection of adverse drug reactions (ADRs) and drug-induced toxicity
Siyun Yang, Supratik Kar
Artificial Intelligence Chemistry.2023; 1(2): 100011. CrossRef
Rifampicin-induced ER stress and excessive cytoplasmic vacuolization instigate hepatotoxicity via alternate programmed cell death paraptosis in vitro and in vivo
KM Kainat, Mohammad Imran Ansari, Nuzhat Bano, Pankaj Ramji Jagdale, Anjaneya Ayanur, Mahadeo Kumar, Pradeep Kumar Sharma
Life Sciences.2023; 333: 122164. CrossRef
Establishment of a Stable Acute Drug-Induced Liver Injury Mouse Model by Sodium Cyclamate
Quan Zhou, Zhongtian Peng, Xialing Huang
Journal of Inflammation Research.2022; Volume 15: 1599. CrossRef
Mitochondrial toxicants in Xian-Ling-Gu-Bao induce liver injury by regulating the PI3K/mTOR signaling pathway: an in vitro study
Shujuan Piao, Hongwei Lin, Xia Tao, Wansheng Chen
BMC Complementary Medicine and Therapies.2022;[Epub] CrossRef
Kratom-Induced Liver Injury: A Case Series and Clinical Implications
Mahesh Botejue, Gurjot Walia, Omar Shahin, Jyotsna Sharma, Rasiq Zackria
Cureus.2021;[Epub] CrossRef
Colestasis inducida por anabólicos: reporte de caso y revisión de la literatura
Diana Lizeth Cabrera-Rojas, Juliana Soto-Cardona, Jorge Luis Toro-Molina, Juan Camilo Pérez-Cadavid, Juan Ignacio Marín-Zuluaga
Hepatología.2021; : 273. CrossRef
Hepatic drug-metabolizing enzymes and drug transporters in Wilson’s disease patients with liver failure
Sylwia Szeląg-Pieniek, Stefan Oswald, Mariola Post, Joanna Łapczuk-Romańska, Marek Droździk, Mateusz Kurzawski
Pharmacological Reports.2021; 73(5): 1427. CrossRef
Prediction of Drug-Induced Liver Toxicity Using SVM and Optimal Descriptor Sets
Keerthana Jaganathan, Hilal Tayara, Kil To Chong
International Journal of Molecular Sciences.2021; 22(15): 8073. CrossRef
Five Constituents Contributed to the Psoraleae Fructus-Induced Hepatotoxicity via Mitochondrial Dysfunction and Apoptosis
Zhaojuan Guo, Pin Li, Chunguo Wang, Qianjun Kang, Can Tu, Bingqian Jiang, Jingxuan Zhang, Weiling Wang, Ting Wang
Frontiers in Pharmacology.2021;[Epub] CrossRef
Changes in Liver Function Test Results after Korean Medicine Treatment in Patients of a Korean Medicine Hospital: A Retrospective Chart Review
Min Young Yim, Han Byeol Park, Jae Soo Kim, Hyun Jong Lee, Sung Chul Lim, Yun Kyu Lee
Korean Journal of Acupuncture.2021; 38(4): 275. CrossRef
Herb-induced Liver Injury in Asia and Current Role of RUCAM for Causality Assessment in 11,160 Published Cases
Rolf Teschke, Yun Zhu, Jing Jing
Journal of Clinical and Translational Hepatology.2020; 8(2): 200. CrossRef
Embarazo y lesión hepática inducida por medicamentos. Reporte de un caso y revisión de la literatura
Christian Labrador-López, Martín Garzón-Olarte, Rodrigo Daza-Fernández, Julián Martínez-Marín, Jorge Lizarazo-Rodríguez, Juan Carlos Molano-Villa, Juan Carlos Marulanda-Gómez, Mario Rey-Tovar
Hepatología.2020; : 157. CrossRef

Original article

Radiology, Radiotherapy & Diagnostic Imaging
Assessment of solid components of borderline ovarian tumor and stage I carcinoma: added value of combined diffusion- and perfusion-weighted magnetic resonance imaging: See Hyung Kim; Yeungnam Univ J Med. 2019;36(3):231-240. Published online June 13, 2019; DOI: https://doi.org/10.12701/yujm.2019.00234; Correction in: J Yeungnam Med Sci 2020;37(2):147

11,238 View
87 Download
7 Crossref

Abstract PDF

Background
We sought to determine the value of combining diffusion-weighted (DW) and perfusion-weighted (PW) sequences with a conventional magnetic resonance (MR) sequence to assess solid components of borderline ovarian tumors (BOTs) and stage I carcinomas.
Methods
Conventional, DW, and PW sequences in the tumor imaging studies of 70 patients (BOTs, n=38; stage I carcinomas, n=32) who underwent surgery with pathologic correlation were assessed. Two independent radiologists calculated the parameters apparent diffusion coefficient (ADC), Ktrans (vessel permeability), and Ve (cell density) for the solid components. The distribution on conventional MR sequence and mean, standard deviation, and 95% confidence interval of each DW and PW parameter were calculated. The inter-observer agreement among the two radiologists was assessed. Area under the receiver operating characteristic curve (AUC) and multivariate logistic regression were performed to compare the effectiveness of DW and PW sequences for average values and to characterize the diagnostic performance of combined DW and PW sequences.
Results
There were excellent agreements for DW and PW parameters between radiologists. The distributions of ADC, Ktrans and Ve values were significantly different between BOTs and stage I carcinomas, yielding AUCs of 0.58 and 0.68, 0.78 and 0.82, and 0.70 and 0.72, respectively, with ADC yielding the lowest diagnostic performance. The AUCs of the DW, PW, and combined PW and DW sequences were 0.71±0.05, 0.80±0.05, and 0.85±0.05, respectively.
Conclusion
Combining PW and DW sequences to a conventional sequence potentially improves the diagnostic accuracy in the differentiation of BOTs and stage I carcinomas.

Citations

Citations to this article as recorded by

A predictive model for recurrence in patients with borderline ovarian tumor based on neural multi-task logistic regression
Qiulin Ye, Yue Qi, Juanjuan Liu, Yuexin Hu, Xiao Li, Qian Guo, Danye Zhang, Bei Lin
BMC Cancer.2025;[Epub] CrossRef
AUTOETHNOGRAPHIC RESEARCH; DIAGNOSIS AND TREATMENT PROCESS OF BORDERLINE OVARIAN TUMORS AND NURSING CARE EXPERIENCES
Emek Bakanoğlu Kalkavan
Fe Dergi.2025; 17(2): 80. CrossRef
Comparison of conventional diffusion-weighted imaging, diffusion kurtosis imaging and intravoxel incoherent motion in characterization of sonographically indeterminate adnexal masses
Gurkawal Kaur, Smita Manchanda, Raju Sharma, Surabhi Vyas, Devasenathipathy Kandasamy, Smriti Hari, Neerja Bhatla, Sandeep R. Mathur
Abdominal Radiology.2024; 49(5): 1512. CrossRef
Advances in fertility preserving surgery for borderline ovarian tumors
Mingdan Wang, Kuiran Liu
European Journal of Obstetrics & Gynecology and Reproductive Biology.2022; 270: 206. CrossRef
Recurrence characteristics and clinicopathological results of borderline ovarian tumors
Lina Niu, Huihui Tian, Yongjun Xu, Jieqiong Cao, Xu Zhang, Junli Zhang, Jiajia Hou, Weiqin Lv, Junxia Wang, Li Xin, XuFeng Dong, Tao Xu, Yuan Nan, Hua Wei, Xinting Chai, Na Li, Yan Ni, Yun Shang, Lizhen Zhang, Ye Zhao
BMC Women's Health.2021;[Epub] CrossRef
Erratum to “Assessment of solid components of borderline ovarian tumor and stage I carcinoma: added value of combined diffusion- and perfusion-weighted magnetic resonance imaging”
See Hyung Kim
Yeungnam University Journal of Medicine.2020; 37(2): 147. CrossRef
Minimal apparent diffusion coefficient value of the solid component to differentiate borderline and malignant ovarian epithelial tumours: a preliminary report
Sahat B.R.E. Matondang, Avrilia Ekawati, Andrijono Andrijono, Hartono Tjahjadi, Joedo Prihartono
Polish Journal of Radiology.2020; 85: 250. CrossRef

Review article

Gastroenterology and Hepatology
Endoscopic features aiding the diagnosis of gastric mucosa-associated lymphoid tissue lymphoma: Byung Sam Park, Si Hyung Lee; Yeungnam Univ J Med. 2019;36(2):85-91. Published online February 26, 2019; DOI: https://doi.org/10.12701/yujm.2019.00136

15,378 View
254 Download
21 Crossref

Abstract PDF

The incidence of gastric mucosa-associated lymphoid tissue (MALT) lymphoma is increasing worldwide, but the diagnosis is difficult. Most patients are asymptomatic or complain of nonspecific gastrointestinal symptoms. As the endoscopic features of gastric MALT lymphoma are variable and nonspecific, the possibility of this condition may be overlooked during esophagogastroduodenoscopy, and it remain undiagnosed. Therefore, this condition needs to be considered when an abnormal mucosa is observed during this procedure. Biopsy performed during endoscopy is the primary diagnostic test, but false negative results are possible; large numbers of samples should be collected from both normal and abnormal mucosae. Endoscopic ultrasonography is useful to assess the depth of invasion and to predict the treatment response. After treatment, follow-up tests are required every 3 months until complete remission is achieved, and annually thereafter. Early diagnosis of gastric MALT lymphoma is difficult, and its diagnosis and follow-up require wide experience and competent endoscopic technique.

Citations

Citations to this article as recorded by

Clinical management of gastric mucosa-associated lymphoid tissue lymphoma
Ji Yong Ahn
The Korean Journal of Internal Medicine.2026; 41(1): 8. CrossRef
Not Every Headache Warrants a Head CT: A Recurrent Headache Unveiling H. Pylori‐Positive MALToma
Rebal Nahas, Serena Khoury, Emanuel-Youssef Dib, Karam Karam, Elias Fiani, Andee Dzulkarnaen Zakaria
Case Reports in Medicine.2025;[Epub] CrossRef
Value of endoscopic submucosal dissection in diagnosing gastric mucosa-associated lymphoid tissue lymphoma: A case report
Shuo-Hui Li, Wei-Wei Niu, Xiao-Xia Huo, Hong Zhang, Li-Min Shi, Ya-Ting Liu, Jia-Jing Xing, Zhi-Xin Feng, Na Wang
World Journal of Gastroenterology.2025;[Epub] CrossRef
GASTRIC MALT LYMPHOMA – CURRENT DIAGNOSTIC AND THERAPEUTIC STRATEGIES
Jonatan Rataj, Kamil Harenza, Karolina Ollik, Marlena Radzka, Michalina Kosowska, Justyna Jankowska, Adrianna Wiekiera, Mateusz Wiekiera
International Journal of Innovative Technologies in Social Science.2025;[Epub] CrossRef
Endoscopic Semiotics of the Gastritis-Like Form of Primary Gastric Non-Hodgkin Lymphomas
Valeriya Vitalevna Lozovaya, O. A. Malikhova, A. O. Tumanyan
Clinical Oncohematology.2024; 16(4): 380. CrossRef
Uncommon presentation of gastric mucosa-associated lymphoid tissue lymphoma in a 13-year-old girl: acute vomiting of blood as the initial symptom
Xinyu Jin, Xin Jin, Piao Guo, Linjuan Lu, Weisong Sheng, Danrong Zhu
Annals of Medicine & Surgery.2024; 86(5): 3001. CrossRef
Next-Generation-Sequencing of the Human B-Cell Receptor Improves Detection and Diagnosis and Enhances Disease Monitoring in Patients with Gastric Mucosa-Associated Lymphoid Tissue Lymphoma
Chidimma Agatha Akpa, Cora Husemann, Chris Allen, Ann-Christin von Brünneck, Jana Ihlow, Michael Hummel
Journal of Molecular Pathology.2024; 5(3): 292. CrossRef
Characteristics of Gastric Mucosa-associated Lymphoid Tissue Lymphoma in Korea
Tae-Woo Kim, Joon Sung Kim
The Korean Journal of Gastroenterology.2024; 84(6): 243. CrossRef
A rare case of perforated gastric lymphoma presenting a life-threatening condition: A case report
Mohamed Zayati, Mohamed Ali Chaouch, Ahmed Hadj Taieb, Besma Gafsi, Mehdi Ben Abdelwahed, Faouzi Noomen
International Journal of Surgery Case Reports.2023; 112: 109010. CrossRef
Development and evaluation of a double-check support system using artificial intelligence in endoscopic screening for gastric cancer
Hirotaka Oura, Tomoaki Matsumura, Mai Fujie, Tsubasa Ishikawa, Ariki Nagashima, Wataru Shiratori, Mamoru Tokunaga, Tatsuya Kaneko, Yushi Imai, Tsubasa Oike, Yuya Yokoyama, Naoki Akizue, Yuki Ota, Kenichiro Okimoto, Makoto Arai, Yuki Nakagawa, Mari Inada,
Gastric Cancer.2022; 25(2): 392. CrossRef
Mucosa-associated lymphoid tissue lymphoma in the terminal ileum: A case report
Vitor Lauar Pimenta de Figueiredo, Igor Braga Ribeiro, Diogo Turiani Hourneaux de Moura, Cristiano Claudino Oliveira, Eduardo Guimarães Hourneaux de Moura
World Journal of Gastrointestinal Endoscopy.2022; 14(3): 176. CrossRef
Mucosa-associated lymphoid tissue lymphoma in the terminal ileum: A case report
Vitor Lauar Pimenta de Figueiredo, Igor Braga Ribeiro, Diogo Turiani Hourneaux de Moura, Cristiano Claudino Oliveira, Eduardo Guimarães Hourneaux de Moura
World Journal of Gastrointestinal Endoscopy.2022; 14(3): 177. CrossRef
Gastrointestinal Tract Lymphoma
Ji Yong Ahn
The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2022; 22(1): 18. CrossRef
Mucosa-Associated Lymphoid Tissue Lymphoma Masked as Gastric Varices With Acute Upper Gastrointestinal Bleeding: A Case Report
David E Jonason, Michael Linden, Guru Trikudanathan
Cureus.2022;[Epub] CrossRef
Endoscopic submucosal dissection for protruding Helicobacter pylori-negative mucosa-associated lymphoid tissue lymphoma of the stomach: a case report
Mayuko Seya, Osamu Dohi, Katsuma Yamauchi, Hayato Fukui, Hajime Miyazaki, Takeshi Yasuda, Ken Inoue, Naohisa Yoshida, Yukiko Morinaga, Yoshito Itoh
Clinical Journal of Gastroenterology.2022; 15(5): 881. CrossRef
Multimodality imaging findings of infection-induced tumors
Moataz Soliman, Nicholas Guys, Peter Liu, Mariam Moshiri, Christine O. Menias, Vincent M. Mellnick, Hatice Savas, Mohamed Badawy, Khaled M. Elsayes, Ayman H. Gaballah
Abdominal Radiology.2022; 47(11): 3930. CrossRef
Does endoscopic submucosal dissection have its place in the treatment of patients with gastric mucosa associated lymphoid tissue lymphoma localized disease after eradication?
Y Li, Z Wang, X Zhang, J Yang
Acta Gastro Enterologica Belgica.2022; 85(2): 410. CrossRef
Multiple Synchronous Mucosa-Associated Lymphoid Lymphomas Involving in the Stomach, Duodenum, Ileum, and Sigmoid
Chun-Wei Chen, Yang-Yuan Chen, Yung-Fang Chen
Diagnostics.2022; 12(12): 3150. CrossRef
Gastric Mucosa-Associated Lymphoid Tissue Lymphomas Diagnosed by Jumbo Biopsy Using Endoscopic Submucosal Dissection: A Case Report
Jian Han, Jun Wang, Hua-ping Xie
Frontiers in Medicine.2021;[Epub] CrossRef
Pedunculated mucosa-associated lymphoid tissue (MALT) lymphoma causing gastric outlet obstruction
Elena Resina Sierra, Pablo Miranda García, Magdalena Adrados, Cecilio Santander Vaquero
Revista Española de Enfermedades Digestivas.2021;[Epub] CrossRef
Primary mucosal-associated lymphoid tissue extranodal marginal zone lymphoma of the bladder from an imaging perspective: A case report
Zhen-Zhen Jiang, Yuan-Yuan Zheng, Chuan-Ling Hou, Xia-Tian Liu
World Journal of Clinical Cases.2021; 9(32): 10024. CrossRef

Case Report

Pulmonary and Respiratory Medicine
Double primary lung adenocarcinoma diagnosed by epidermal growth factor receptor mutation status: Oh Jung Kwon, Min Hyeok Lee, Sung Ju Kang, Seul Gi Kim, In Beom Jeong, Ji Yun Jeong, Eun Jung Cha, Do Yeun Cho, Young Jin Kim, Ji Woong Son; Yeungnam Univ J Med. 2017;34(2):270-274. Published online December 31, 2017; DOI: https://doi.org/10.12701/yujm.2017.34.2.270

3,318 View
14 Download

Abstract PDF: A nodular density was detected on a chest radiograph taken from a 57-year-old Korean woman who was visiting a hospital for a routine check. Chest computed tomography revealed a 4.8 cm lobulated mass in the right lung and another focal nodular lesion in the left lung; biopsies of both lungs revealed adenocarcinoma. We conducted DNA sequencing and peptide nucleic acid clamping to investigate the potential double primary lung cancer. The results verified that the mass in the right lung had a mutation in the epidermal growth factor receptor, whereas the nodule in the left lung had a wild-type sequence, showing that these two were genetically different cancers from one another. Thus, we demonstrate that genetic testing is useful in determining double primary lung cancer, and we herein report on this case.

Original Articles

Pediatrics, Perinatology, and Child Health
Clinical courses and diagnoses of neonates who are transferred due to mild respiratory distress soon after birth in a university hospital.: Jee Hyue Seo, Kyo Ho Lee, Eun Sil Lee; Yeungnam Univ J Med. 2014;31(2):89-93. Published online December 31, 2014; DOI: https://doi.org/10.12701/yujm.2014.31.2.89

2,662 View
16 Download

Abstract PDF: BACKGROUND
This study was conducted to investigate the epidemiological features, clinical courses, and diagnoses of neonates who are transferred to neonatal intensive care unit of Yeungnam University Hospital due to tachypnea soon after birth. METHODS: Based on medical records, we performed a retrospective study of neonatal intensive care unit admissions due to tachypnea from January 2010 to December 2013. RESULTS: A total of 311 neonates were included in this study. The patient characteristics showed male predominance at 2.65:1. Among the 311 neonates with tachypnea, 127 (40.8%) neonates needed oxygen supply, and 54 (17.4%) neonates needed assisted mechanical ventilation. Transient tachypnea of the newborns (TTN) (158, 50.8%) showed the highest incidence, followed by pneumonia (63, 20.3%), extrapulmonary infection (37, 11.9%), respiratory distress syndrome (21, 6.8%), air leak (16, 5.1%), meconium aspiration syndrome (12, 3.9%), congenital heart disease (5, 1.6%), metabolic acidosis (3, 1%), primary pulmonary hypertension of newborns (2, 0.6%) and anemia (2, 0.6%). CONCLUSION: Although the neonates with tachypnea showed no other respiratory distress symptom, clinicians should be aware of the possibility of other pulmonary diseases as well as TTN and their extra-pulmonary causes. If tachypnea does not improve within a few hours, the clinician should consider further evaluation and management as soon as possible.

Pulmonary and Respiratory Medicine
The Role of Dynamic CT for the Differential Diagnosis of Solitary Pulmonary Nodule.: Jin Hong Chung, Won Jong Park, Ihn Ho Cho; Yeungnam Univ J Med. 2008;25(2):102-107. Published online December 31, 2008; DOI: https://doi.org/10.12701/yujm.2008.25.2.102

2,278 View
1 Download

Abstract PDF: BACKGROUND
Malignant pulmonary nodules account for 30 to 40 percent of all solitary pulmonary nodules (SPNs). Therefore, characterization of SPNs is very important for treatment. Recently, dynamic CT has been widely used for tissue characterization and formation of differential diagnoses. The purpose of this study was to evaluate the ability of dynamic CT to formulate the differential diagnosis of SPNs. MATERIALS AND METHODS: Nineteen patients with SPNs underwent dynamic CT (unenhanced scans, followed by a series of images at 20, 40, 60, 80, 100, 120, 140, 160, and 180 sec after intravenous injection of contrast medium). Diagnosis of SPN was performed based on pathologic findings in needle biopsy samples. Peak enhancement, net enhancement, slope of enhancement, and maximum relative enhancement ratio of the SPN were measured on dynamic CT, and Levene's test was performed to assess benignancy and malignancy. RESULTS: Twelve SPNs were confirmed to have malignant pathology. There were no significant differences between benign and malignant nodules with respect to peak enhancement (p=0.787), net enhancement (p=0.135), or slope of enhancement (p=0.698). The maximal enhancement ratio was increased in malignancy compared to benignancy, but the difference was not statistically significant (p=0.094). CONCLUSION: In our study, the hemodynamic characteristics of dynamic CT were not significantly different between benign and malignant nodules. Therefore, long-term studies of larger patient samples are required to confirm our findings.

Review Article

Urology
Diagnosis of Malignant Lesion in Patients with Lower Urinary Tract Symptoms: Tong Choon Park; Yeungnam Univ J Med. 2007;24(2 Suppl):S1-11. Published online December 31, 2007; DOI: https://doi.org/10.12701/yujm.2007.24.2S.S1

2,002 View
5 Download

Abstract PDF: Some patients, especially with chronic disease such as diabetes, who suffer from lower urinary tract symptoms (LUTS) just want to take prolonged oral medication (anticholinergics or alpha blockers) without proper evaluation for basic causes. LUTS is commonly occurred by urinary tract infection, several chronic diseases and/or aging itself. However, we should not pass over the fact that LUTS also can be evoked by malignancy. Because there is a higher detection rate of malignancy in patients with microscopic hematuria, urine cytology must be done with ultrasonography, IVP and cystoscopy. In those patients aged over 50 years or high risk group for urothelial carcinoma, it is mandatory to undergo ultrasonography and cystoscopy, even if there is no abnormalities on their urinalysis and urine cytology.

Original Articles

Pediatrics, Perinatology, and Child Health
Neuroblastoma : Computed Tomographic Finding.: Jae Woon Kim, Jong Oh Choi, Jae Ho Cho, Mi Soo Hwang, Bok Hwan Park; Yeungnam Univ J Med. 1996;13(1):134-140. Published online June 30, 1996; DOI: https://doi.org/10.12701/yujm.1996.13.1.134

2,232 View
2 Download

Abstract PDF: Recently many studies have shown the usefulness of computed tomogram in diagnosing abdominal mass when clinical and conventional radiologic examinations fail to reveal the nature of abdominal mass or the cause of abdominal distension. To evaluate the usefulness of CT in diagnosing neuroblastoma, we retrospectively analyzed computed tomographic findings of 16 neuroblastoma patients, who pathologically proved in Yeungnam University Hospital from 1986 to 1995. The age range of the patients studied were from 8months to 18years. The most frequent sith of origin was adrenal gland and the next was retroperitioneum. The presenting symptoms were palpable mass, abdominal distension, and abdominal pain.- The viewpoints of this analysis were tumoral calcifications, midline cross, shape, margin, internal structure, contrast enhancement patterns, major vessel involvement, and lymph node involvement. ':haracteristic CT findings were 'as follows: Fine dense curvillinear calcification within the tumor(56%), midline cross(50%), lobulation(75%), well-circumscribed margin(56%), cystic degeneration(56%), heterogeneous contrast enhancement(690/o), encasement of major vessels such as aorta, IVC and celiac trunk(50%), and paraaortic lymphadenopathy(87%). We conclude that these CT findings were very common and could be helpful in diagnosting and differentiation neuroblastoma in infant and children.

Psychiatry and Mental Health
A study on somatization in psychiatric patients.: Jong Bum Lee, Hyung Bae Park; Yeungnam Univ J Med. 1992;9(1):68-74. Published online June 30, 1992; DOI: https://doi.org/10.12701/yujm.1992.9.1.68

2,227 View
1 Download

Abstract PDF: To evaluate the simplicity and efficacy of the 7-symptom screen test for somatization disorder, the authors tried 7-symptom screen test to find out the easiness in diagnosing the somatization disorder and to evaluate the simplicity and efficacy of it from Mar 1991 to Feb 1992. The objects were 135 female outpatients who visited Department of Psychiatry, College of Medicine, Yeungnam University. The results were as follows; The discriminant index was over 3.0 for all 7 symptoms and two item accuracy was 89% (sensitivity 99%, specificity 77%), three item accuracy was 87% (sensitivity 83%, specificity 90%). In discriminant analysis, the cut off score for the criteria of somatization disorder was 87% when three or more symptoms were checked for 7-symptoms. This result means that 7-symptom screen test is the simple and accurate method for screening and diagnosing the somatization disorder.

First
Prev
Page of 1
Next
Last

Search