Journal of Yeungnam Medical Science

Review Article

Pathology and Forensic Medicine
Methods of Margin Assessment in Breast Conserving Surgery: Young Kyung Bae; Yeungnam Univ J Med. 2007;24(2 Suppl):S262-269. Published online December 31, 2007; DOI: https://doi.org/10.12701/yujm.2007.24.2S.S262

2,435 View
2 Download
1 Crossref

Breast conserving surgery has become the preferred method of treatment for breast cancer. Therefore clear surgical margin is critical to minimize the risk of local recurrence. Although paraffin section of inked surgical margin is the gold standard for margin assessment, this process is time consuming, and results are not available until after the operation. Several methods of intraoperative margin assessment are available including gross evaluation of the tumor specimen, specimen slice radiography, pathologic evaluation with touch preparation cytology or frozen section analysis. Here I review three methods of pathologic evaluation -macroscopic evaluation, touch preparation cytology, and frozen section- and deal with problems and pitfalls that can happen in routine diagnostic fields.

Citations

Citations to this article as recorded by

A Study on the Quality of a Frozen Section of Breast Resection Margin during Breast-Conserving Surgery
Byung-Il Choi, Su-Sie Chin
The Korean Journal of Clinical Laboratory Science.2021; 53(3): 233. CrossRef

Original Article

Oncology and Cancer Research
Screening Examination of Breast Cancer: Review of the Recommended Guidelines.: Myung Ho Shin, Mi Soo Hwang, Bok Hwan Park; Yeungnam Univ J Med. 1999;16(2):342-346. Published online December 31, 1999; DOI: https://doi.org/10.12701/yujm.1999.16.2.342

2,126 View
1 Download

Abstract PDF: BACKGROUND
Delays in breast cancer diagnosis may occur in young women due to a low index of suspicion. The purpose of this study was to compare mammography and breast sonography in detection of breast cancer and to suggest a reasonable guideline for breast cancer screening examination. MATERIALS AND MATHODS: Among 820 patients, 102 patients were under 35 years and 122 patients were above 60 years of age. We reviewed medical records, mammograms and/or ultrasonography of 49 patients under 35 years and 48 patients above 60 years of age with pathologically-proven breast cancer. Pathological reports were as follows: Invasive ductal carcinoma(IDC) was present 61.2% of patients in the young age group and ductal carcinoma in situ(DCIS) in 16.3%. IDC was present in 66.6% of the patients in the old age group, and DCIS in 8.33%. We analyzed mammography and ultrasonography to evaluate their usefullness in detecting breast cancer in patients under 35 years and over 60 years of age. RESULTS: The mammographic results are as follows: 1) detection rate of lesion: 83.8%(under 35yrs), 100%(over 60yrs) 2) sensitivity of cancer: 67.6%(under 35yrs), 91.2%(over 60yrs) The ultrasonographic results are as follows: 1) detection rate of lesion: 100% 2) sensitivity of cancer: 87.2%(under 35yrs), 96.7%(over 60yrs) The breas cancer detection rate in women under 35 years old was comparable to that of women above 60 years old in our study. CONCLUSION: A striking histologic finding in the two groups was a higher incidence of nuclear Grade II and III tumors. This finding correlates with the reported increased incidence of high grade tumors inyoung women and may correlae with the poorer prognosis of breast cancer in young patients. We conclude that early screening examination is helpful for early detection of breast cancer in women under age 35.

First
Prev
Page of 1
Next
Last

Search