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JYMS : Journal of Yeungnam Medical Science

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Review article
Pulmonary and Respiratory Medicine
Creating home-based pulmonary rehabilitation programs for patients with asthma: insights from practice
Cahidenur Koçak, Massimiliano Polastri, Esra Pehlivan
J Yeungnam Med Sci. 2025;42:57.   Published online September 17, 2025
DOI: https://doi.org/10.12701/jyms.2025.42.57
  • 3,902 View
  • 198 Download
  • 1 Web of Science
  • 2 Crossref
AbstractAbstract PDF
Pulmonary rehabilitation (PR) plays a crucial role in the management of asthma symptoms and addresses the physical, psychological, and social consequences of asthma. However, difficulties in accessing hospital-based PR programs could result in underutilization of these services. Alternative models such as home-based PR and telerehabilitation are promising in their potential to mitigate barriers and improve adherence. It is well known that PR has a significant positive impact on both respiratory and physical functions, as well as individual well-being. Indeed, such effects have been confirmed in several studies in which psychological symptoms (i.e., anxiety and depression), physical capacity, and health-related quality of life improved in patients with asthma. Nonetheless, to sustain treatment-related benefits in the long term, PR programs must be tailored to individual needs and planned using a multidisciplinary and holistic approach. Given the high prevalence of asthma in children, home-based PR programs may offer substantial benefits to the pediatric population and warrant further investigation. The present review describes the characteristics of home-based PR and provides evidence on current practices for the management of asthma and the development of a patient-centered therapeutic approach.

Citations

Citations to this article as recorded by  
  • The Role of Adherence to Pharmacological and Non-Pharmacological Treatments in Hospitalized Patients with Obstructive Airway Diseases
    Büşra Durak, Galip Koçyiğit, Hasan Can Alagöz, Canan Gündüz Gürkan
    Dicle Tıp Dergisi.2026; 53(1): 67.     CrossRef
  • Feasibility of app-based pulmonary telerehabilitation program for textile dyeing workers with respiratory symptoms: a quasi-experimental study
    Myeong Geun Jeong, Gun Seo Jung, Kyoung Tae Kim
    Journal of Yeungnam Medical Science.2026; 43: 20.     CrossRef
Focused Review article
Pulmonary and Respiratory Medicine
Biological treatments for severe asthma
Hyun Jung Jin
Yeungnam Univ J Med. 2020;37(4):262-268.   Published online September 11, 2020
DOI: https://doi.org/10.12701/yujm.2020.00647
  • 11,467 View
  • 195 Download
  • 14 Crossref
AbstractAbstract PDF
Severe asthma patients comprise about 3% to 13% of all asthma patients, but they have higher hospital utilization rates and higher medical costs than those of nonsevere asthma patients. Treatment methods for severe asthma patients are still lacking; however, the recent development of biologics is expected to have a positive effect. The biological therapies developed so far are mainly aimed at treating asthma patients with type 2 inflammation. These biologics have been found to reduce symptoms of asthma, improve lung function, reduce the use of oral corticosteroids, and improve quality of life of patients. This article reviews the mechanism of action and indications for approved biologics and discusses what should be considered when choosing biologics.

Citations

Citations to this article as recorded by  
  • Advanced bispecific antibody design and inhaled biologics; emerging strategies for asthma
    Zeina Kassem, Jenny K. W. Lam, Hanieh Khalili
    RSC Pharmaceutics.2026; 3(3): 630.     CrossRef
  • Allergen Immunotherapy for the Prevention and Treatment of Asthma
    Thierry Batard, Camille Taillé, Laurent Guilleminault, Andrzej Bozek, Véronique Bordas‐Le Floch, Oliver Pfaar, Walter G. Canonica, Cezmi Akdis, Mohamed H. Shamji, Laurent Mascarell
    Clinical & Experimental Allergy.2025; 55(2): 111.     CrossRef
  • Determinants of cost-effectiveness results of biological therapies for severe asthma: a systematic methodological assessment
    Laura de la Torre-Pérez, Marilina Santero, Wendy Nieto-Gutierrez, Christine Giesen, Angela Nardin, Claudia Cosma, Pedro Silva Pires, Andrea Guida, Marcello Simonini, Camila Quirland Lazo, Feng Xie, Pablo Alonso-Coello
    Journal of Clinical Epidemiology.2025; 178: 111621.     CrossRef
  • Current and Novel Biologic Therapies for Patients with Asthma and Nasal Polyps
    Hanna K. Mandl, Jessa E. Miller, Daniel M. Beswick
    Otolaryngologic Clinics of North America.2024; 57(2): 225.     CrossRef
  • Moderate-High Blood Eosinophilia Is Associated with Increased Hospitalization and Other Asthma Comorbidities
    Sara Naharro-González, Clara Lorente-Sorolla, José Manuel Rodrigo-Muñoz, Marcela Valverde-Monge, Erwin Javier Pinillos-Robles, Diana Betancor, Mar Fernández-Nieto, Diana Sánchez-Mellado, Marta Gil-Martínez, Jessica Mireya Santillán-Coello, José Miguel Vil
    Biomolecules.2024; 14(1): 126.     CrossRef
  • Biologic Therapies across Nasal Polyp Subtypes
    Kody G. Bolk, Sarah K. Wise
    Journal of Personalized Medicine.2024; 14(4): 432.     CrossRef
  • Evaluation of multiple-flows exhaled nitric oxide and its clinical significance in severe asthmatic patients treated with biologics: a prospective real-life study
    Tommaso Pianigiani, Simona Luzzi, Akter Dilroba, Martina Meocci, Elisa Salvadori, Lorenzo Alderighi, Laura Bergantini, Miriana d’Alessandro, Piersante Sestini, Elena Bargagli, Paolo Cameli
    Journal of Asthma.2024; 61(12): 1619.     CrossRef
  • Long-term Safety and Efficacy of Dupilumab in Patients With Uncontrolled, Moderate-to-Severe Asthma Recruited From Korean Centers: A Subgroup Analysis of the Phase 3 LIBERTY ASTHMA TRAVERSE Trial
    Chin Kook Rhee, Jung-Won Park, Heung-Woo Park, Hayeon Noh, Jerome Msihid, You Sook Cho
    Allergy, Asthma & Immunology Research.2024; 16(4): 372.     CrossRef
  • Incremental net monetary benefit of biologic therapies in moderate to severe asthma: a systematic review and meta-analysis of economic evaluation studies
    Sajesh K. Veettil, Vanessa Vincent, Taylor Shufelt, Emma Behan, M. Sakil Syeed, Ammarin Thakkinstian, David C. Young, Nathorn Chaiyakunapruk
    Journal of Asthma.2023; 60(9): 1702.     CrossRef
  • Tackling the cytokine storm using advanced drug delivery in allergic airway disease
    Vyoma K. Patel, Sukriti Vishwas, Rajan Kumar, Gabriele De Rubis, Shakti D. Shukla, Keshav Raj Paudel, Bikash Manandhar, Thakur Gurjeet Singh, Dinesh Kumar Chellappan, Monica Gulati, Indu Pal Kaur, Venkata Sita Rama Raju Allam, Philip M. Hansbro, Brian G.
    Journal of Drug Delivery Science and Technology.2023; 82: 104366.     CrossRef
  • The evolving landscape of immunotherapy for the treatment of allergic conditions
    Aarti Pandya, Esosa Adah, Bridgette Jones, Rachel Chevalier
    Clinical and Translational Science.2023; 16(8): 1294.     CrossRef
  • Effect of Dupilumab in Korean Patients With Uncontrolled Moderate-to-Severe Asthma: A LIBERTY ASTHMA QUEST Sub-analysis
    Chin Kook Rhee, Jung-Won Park, Heung-Woo Park, You Sook Cho
    Allergy, Asthma & Immunology Research.2022; 14(2): 182.     CrossRef
  • The role of peripheral eosinophilia in diagnosing lung disorders: experience from a single pneumonological center
    Justyna Fijołek, Elzbieta Wiatr, Dorota Piotrowska-Kownacka, Kazimierz Roszkowski-Sliz
    Multidisciplinary Respiratory Medicine.2021;[Epub]     CrossRef
  • Advances in the science and treatment of respiratory diseases
    Jin Hong Chung
    Yeungnam University Journal of Medicine.2020; 37(4): 251.     CrossRef
Original Article
Pediatrics, Perinatology, and Child Health
The clinical observations in childhood asthma.
Kih Yeon Song, Yong Hyoun Park, Jin Gon Jun, Young Hwan Lee, Chun Dong Kim
Yeungnam Univ J Med. 1992;9(2):239-247.   Published online December 31, 1992
DOI: https://doi.org/10.12701/yujm.1992.9.2.239
  • 2,326 View
  • 2 Download
AbstractAbstract PDF
A clinical analysis was done on 134 cases with bronchial asthma who were admitted to the Department of Pediatrics Yeungnam University from May 1987 to October 1991. The results were as follows: 1) The peak age of bronchial asthma was under 2 years. The sex ratio of male to female was 2.9:1. 2) The outbreak of bronchial asthma was most common in fall, especially in September. 3) The past history of other allergic diseases were present in 22.4% of patients (30/134 cases), and the previous bronchiolitis in infancy were experienced in 12.7% of patients (17/134 cases). 4) According to the skin test for allergens done by RAST, the most common allergens were Mites and House dust. 5) Eosinophilia (T.E.C>250/min) was found in 29.1%t of patients, and elevated lgE level (>200 IU/ml) was found in 63.2% of patients. 6) No significant differences in the serum lgE level were found between male and female patients. No significant differences in the serum lgE level were found between asthma patients with and without other allergic diseases. 7) The serum lgE level of school aged patients was significant higher than that of preschool aged (p<0.01).

JYMS : Journal of Yeungnam Medical Science
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