Journal of Yeungnam Medical Science

Resident fellow section: Clinical vignette

Neurology
Differential diagnosis of motor weakness in the right lower limb of a 59-year-old male patient: Jae Hwa Bae, Soyoung Kwak; J Yeungnam Med Sci. 2022;39(4):347-351. Published online September 20, 2022; DOI: https://doi.org/10.12701/jyms.2022.00535

6,947 View
82 Download
1 Crossref

PDF

Citations

Citations to this article as recorded by

Advances in Imaging for Metastatic Epidural Spinal Cord Compression: A Comprehensive Review of Detection, Diagnosis, and Treatment Planning
Paschyanti R Kasat, Shivali V Kashikar, Pratapsingh Parihar, Pratiksha Sachani, Priyal Shrivastava, Smruti A Mapari, Utkarsh Pradeep, Gautam N Bedi, Paritosh N Bhangale
Cureus.2024;[Epub] CrossRef

Focused Review article

Neurology
Pain in amyotrophic lateral sclerosis: a narrative review: Soyoung Kwak; J Yeungnam Med Sci. 2022;39(3):181-189. Published online June 8, 2022; DOI: https://doi.org/10.12701/jyms.2022.00332

14,672 View
206 Download
16 Web of Science
17 Crossref

Abstract PDF

Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative condition characterized by loss of motor neurons, resulting in motor weakness of the limbs and/or bulbar muscles. Pain is a prevalent but neglected symptom of ALS, and it has a significant negative impact on the quality of life of patients and their caregivers. This review outlines the epidemiology, clinical characteristics, underlying mechanisms, and management strategies of pain in ALS to improve clinical practice and patient outcomes related to pain. Pain is a prevalent symptom among patients with ALS, with a variable reported prevalence. It may occur at any stage of the disease and can involve any part of the body without a specific pattern. Primary pain includes neuropathic pain and pain from spasticity or cramps, while secondary pain is mainly nociceptive, occurring with the progression of muscle weakness and atrophy, prolonged immobility causing degenerative changes in joints and connective tissue, and long-term home mechanical ventilation. Prior to treatment, the exact patterns and causes of pain must first be identified, and the treatment should be tailored to each patient. Treatment options can be classified into pharmacological treatments, including nonsteroidal anti-inflammatory drugs, antiepileptic drugs, drugs for cramps or spasticity, and opioid; and nonpharmacological treatments, including positioning, splints, joint injections, and physical therapy. The development of standardized and specific assessment tools for pain-specific to ALS is required, as are further studies on treatments to reduce pain, diminish suffering, and improve the quality of life of patients with ALS.

Citations

Citations to this article as recorded by

Resting-State EEG Oscillations in Amyotrophic Lateral Sclerosis (ALS): Toward Mechanistic Insights and Clinical Markers
James Chmiel, Marta Stępień-Słodkowska
Journal of Clinical Medicine.2025; 14(2): 545. CrossRef
Progressive Bulbar Palsy (PBP) or Bulbar Onset MND: “A Case Report”
Sagar S. Bhovare, Akhataribano S. Sayyad
Journal of Pharmacy and Bioallied Sciences.2025; 17(Suppl 1): S971. CrossRef
Health-Related Quality of Life, Psychological Health, and Patient-Reported Outcomes of Amyotrophic Lateral Sclerosis Patients in China
Dilip Dhakal, Congzhou Chen, Bo Zhang, Guanqiao Li
Brain Sciences.2025; 15(7): 696. CrossRef
Analysis of factors influencing sleep disorders in patients with amyotrophic lateral sclerosis
Qianping Jiang, Dan Yang, Rui Jiang, Shilei Wan, Miao Wu, Dandan Xu, Jing Zhou
Scientific Reports.2025;[Epub] CrossRef
Cutting-edge treatments in amyotrophic lateral sclerosis: the role of molecular pathogenesis in targeted therapies
Ramin Raoufinia, Ghazal Alyari, Amin Tadayoni nia, Mohammad Reza Abbaszadegan, Ali Mahmoudi, Sajjad Shafaeibajestan, Ehsan Saburi, Jalil Tavakol-Afshari, Mehdi Hassani, Faezeh Jamali, Shahram Salari, Amir Reza Boroumand, Hamid reza Rahimi
Stem Cell Research & Therapy.2025;[Epub] CrossRef
Greek Registry for Amyotrophic Lateral Sclerosis (ALS‐GR): An Observational Cohort of Individuals With ALS Across 11 Specialized Centers in Greece
Ioannis Liampas, Vasilios K. Kimiskidis, Vasiliki Zouvelou, Dimitra Veltsista, Afroditi Moscholouri, Eleftherios Triantafyllou, Ariadni Daponte, Sofia Xirou, Angeliki‐Erato Sterpi, Stavroula Salakou, Vasiliki Poulidou, Marianthi Arnaoutoglou, Zisis Tsouri
European Journal of Neurology.2025;[Epub] CrossRef
Rehabilitation in Amyotrophic Lateral Sclerosis: Recommendations for Clinical Practice and Further Research
Andreas Gratzer, Natalie Gdynia, Nadine Sasse, Rainer Beese, Cordula Winterholler, Yvonne Bauer, Carsten Schröter, Hans-Jürgen Gdynia
Journal of Clinical Medicine.2025; 14(23): 8590. CrossRef
Health-related quality of life across disease stages in patients with amyotrophic lateral sclerosis: results from a real-world survey
Katie Stenson, T. E. Fecteau, L. O’Callaghan, P. Bryden, J. Mellor, J. Wright, L. Earl, O. Thomas, H. Iqbal, S. Barlow, S. Parvanta
Journal of Neurology.2024; 271(5): 2390. CrossRef
Amyotrophic Lateral Sclerosis and Pain: A Narrative Review from Pain Assessment to Therapy
Vincenzo Pota, Pasquale Sansone, Sara De Sarno, Caterina Aurilio, Francesco Coppolino, Manlio Barbarisi, Francesco Barbato, Marco Fiore, Gianluigi Cosenza, Maria Beatrice Passavanti, Maria Caterina Pace, Enzo Emanuele
Behavioural Neurology.2024;[Epub] CrossRef
Non-motor symptoms in patients with amyotrophic lateral sclerosis: current state and future directions
Bogdan Bjelica, Maj-Britt Bartels, Jasper Hesebeck-Brinckmann, Susanne Petri
Journal of Neurology.2024; 271(7): 3953. CrossRef
Perceived Pain in People Living with Amyotrophic Lateral Sclerosis—A Scoping Review
Debora Rosa, Laura Ingrande, Ilaria Marcomini, Andrea Poliani, Giulia Villa, Martina Sodano, Duilio Fiorenzo Manara
Nursing Reports.2024; 14(4): 3023. CrossRef
Pain in Amyotrophic Lateral Sclerosis Is Underrated
Soyoung Kwak, Min Cheol Chang
International journal of Pain.2024; 15(2): 51. CrossRef
Likely Pathogenic Variants of Cav1.3 and Nav1.1 Encoding Genes in Amyotrophic Lateral Sclerosis Could Elucidate the Dysregulated Pain Pathways
Zsófia Flóra Nagy, Balázs Sonkodi, Margit Pál, Péter Klivényi, Márta Széll
Biomedicines.2023; 11(3): 933. CrossRef
Palliative Care in Amyotrophic Lateral Sclerosis
Sebastiano Mercadante, Lou'i Al-Husinat
Journal of Pain and Symptom Management.2023; 66(4): e485. CrossRef
The blind spot and challenges in pain management
Min Cheol Chang
Journal of Yeungnam Medical Science.2022; 39(3): 179. CrossRef
Synucleinopathy in Amyotrophic Lateral Sclerosis: A Potential Avenue for Antisense Therapeutics?
Bradley Roberts, Frances Theunissen, Francis L. Mastaglia, P. Anthony Akkari, Loren L. Flynn
International Journal of Molecular Sciences.2022; 23(16): 9364. CrossRef
Herbal medicine and acupuncture relieved progressive bulbar palsy for more than 3 years: A case report
Siyang Peng, Weiqian Chang, Yukun Tian, Yajing Yang, Shaohong Li, Jinxia Ni, Wenzeng Zhu
Medicine.2022; 101(45): e31446. CrossRef

Review article

Physical therapy, Sports Therapy, and Rehabilitation
Home mechanical ventilation in children with chronic respiratory failure: a narrative review: Soyoung Kwak; J Yeungnam Med Sci. 2023;40(2):123-135. Published online May 27, 2022; DOI: https://doi.org/10.12701/jyms.2022.00227

13,151 View
301 Download
16 Web of Science
20 Crossref

Abstract PDF

Advances in perinatal and pediatric intensive care and recent advances in mechanical ventilation during the last two decades have resulted in an exponential increase in the number of children undergoing home mechanical ventilation (HMV) treatment. Although its efficacy in chronic respiratory failure is well established, HMV in children is more complex than that in adults, and there are more considerations. This review outlines clinical considerations for HMV in children. The goal of HMV in children is not only to correct alveolar hypoventilation but also to maximize development as much as possible. The modes of ventilation and ventilator settings, including ventilation masks, tubing, circuits, humidification, and ventilator parameters, should be tailored to the patient’s individual characteristics. To ensure effective HMV, education for the parent and caregiver is important. HMV continues to change the scope of treatment for chronic respiratory failure in children in that it decreases respiratory morbidity and prolongs life spans. Further studies on this topic with larger scale and systemic approach are required to ensure the better outcomes in this population.

Citations

Citations to this article as recorded by

Ventilación mecánica prolongada y paciente traqueostomizado en cuidados intensivos pediátricos
Rafael González Cortés, Martí Pons Òdena, Mirella Gaboli, María Angeles García-Teresa
Medicina Intensiva.2026; 50(1): 502294. CrossRef
Prolonged mechanical ventilation and tracheostomised Paediatric
Rafael González Cortés, Martí Pons Òdena, Mirella Gaboli, María Angeles García-Teresa
Medicina Intensiva (English Edition).2026; 50(1): 502294. CrossRef
Telemedicine outcome of mechanically ventilated children in Brazilian pediatric intensive care units
Aristóteles de Almeida Pires, Luciano Remião Guerra, João Ronaldo Mafalda Krauzer, Luciane Gomes da Cunha, Mariana Motta Dias da Silva, Vanessa Cristina Jacovas, Hilda Maria Rodrigues Moleda Constant, Taís de Campos Moreira, Paulo Márcio Pitrez, Felipe Ce
Clinical and Experimental Pediatrics.2026; 69(2): 140. CrossRef
Swedish national cohort of children living with long-term respiratory support (DISCOVERY-P): cohort profile
Johan Florén, Magnus Ekström, Berit Lindahl, Agneta Markström, Andreas Palm, Åsa Israelsson-Skogsberg
BMJ Open.2025; 15(4): e090241. CrossRef
No socioeconomic disparities in the availability of personal care assistance: a population-based cohort analysis of children living with respiratory support
Johan Florén, Åsa Israelsson-Skogsberg, Magnus Ekström, Berit Lindahl, Agneta Markström, Andreas Palm
International Journal for Equity in Health.2025;[Epub] CrossRef
Discharge Practice Variability in Pediatric Chronic Home Invasive Ventilation
Guillermo Beltran‐Ale, Ryne Simpson, Terri Magruder, Ajay S. Kasi, Amit Agarwal, Jake A. Kaslow
Pediatric Pulmonology.2025;[Epub] CrossRef
Impact of Physical Exercise and Home Care on Health Outcomes in Children with Disabilities: A Systematic Review
Abhishek Sharma, Nidhi Sharma, Aksh Chahal
Heart and Mind.2025; 9(4): 298. CrossRef
Work‐Life Perceptions of Danish Personal Care Assistants Working in the Home Mechanical Ventilation Setting—A Survey Study
Pernille Bang Nielsen, Anette Bjerregaard Alrø, Anna Holm, Dorthe Enggaard Trojel, Pia Dreyer
Scandinavian Journal of Caring Sciences.2025;[Epub] CrossRef
Home paediatric CPAP/NIV: the basics
Sonia Khirani, Alessandro Amaddeo, Lucie Griffon, Marine Dosso, Meryl Vedrenne-Cloquet, Clément Poirault, Benjamin Dudoignon, Brigitte Fauroux
Sleep Medicine.2025; 136: 106886. CrossRef
Clinical applications of home mechanical ventilation in children
Hamin Kim, Kyung Won Kim
Archives of Pediatric Critical Care.2025; 3(2): 57. CrossRef
The follow‐up of children on home invasive mechanical ventilation after hospital discharge
Halime Nayır Büyükşahin, Ebru Yalcın
Pediatric Pulmonology.2024; 59(8): 2145. CrossRef
Identifying and managing psychosocial problems in children on home invasive mechanical ventilation
Gizem Özcan, Nazan Çobanoğlu
Pediatric Pulmonology.2024; 59(8): 2149. CrossRef
Management of gastrointestinal and nutritional problems in children on home invasive mechanical ventilation
Ceyda Tuna Kirsaçlioğlu
Pediatric Pulmonology.2024; 59(8): 2170. CrossRef
Indications and practice of home invasive mechanical ventilation in children
Secahattin Bayav, Nazan Çobanoğlu
Pediatric Pulmonology.2024; 59(8): 2210. CrossRef
Rehabilitation in children with home invasive mechanical ventilation
Aysun Genç, Birkan Sonel Tur
Pediatric Pulmonology.2024; 59(8): 2203. CrossRef
Transitioning children using home invasive mechanical ventilation from hospital to home: Discharge criteria, disparities, and ethical considerations
Jennifer Henningfeld, Annie B. Friedrich, Grace Flanagan, Cynthia Griffith, Anna Hughes, Lisa Molkentine, Rebecca Steuart, Stuart Wilkinson, Christopher D. Baker
Pediatric Pulmonology.2024; 59(8): 2113. CrossRef
Mask interfaces and devices for home noninvasive ventilation in children
Sonia Khirani, Vivian Ducrot
Pediatric Pulmonology.2024; 59(6): 1528. CrossRef
Home Mechanical Ventilation in Children: Complications and Benefits—A Two-Year Experience at a Referral Children's Hospital
Majid Keivanfar, Mahnaz Kheiri, Sharareh Babaie, Mohsen Reisi
Iranian Journal of Pediatrics.2024;[Epub] CrossRef
Mapping health-related quality of life of children and families receiving pediatric invasive home mechanical ventilation: a scoping review protocol
Keisha White Makinde, Maysara Mitchell, Alexandra F. Merz, Michael Youssef
Systematic Reviews.2024;[Epub] CrossRef
The journey to home for children using home mechanical ventilation
Eunju Ha
Archives of Pediatric Critical Care.2024; 2(2): 33. CrossRef

First
Prev
Page of 1
Next
Last

Search