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Case report
- Infectious Disease
- Community-acquired Achromobacter xylosoxidans infection presenting as a cavitary lung disease in an immunocompetent patient
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Chan Hee Hwang
, Woo Jin Kim, Hye Young Jwa, Sung Heon Song - Yeungnam Univ J Med. 2020;37(1):54-58. Published online August 12, 2019
- DOI: https://doi.org/10.12701/yujm.2019.00276
- 12,434 View
- 152 Download
- 6 Crossref
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Abstract
PDF - Achromobacter xylosoxidans is a gram-negative bacterium that can oxidize xylose. It is commonly found in contaminated soil and water but does not normally infect immunocompetent humans. We report a case of a cavitary lung lesion associated with community-acquired A. xylosoxidans infection, which mimicked pulmonary tuberculosis or lung cancer in an immunocompetent man. The patient was hospitalized due to hemoptysis, and chest computed tomography (CT) revealed a cavitary lesion in the superior segment of the left lower lobe. We performed bronchoscopy and bronchial washing, and subsequent bacterial cultures excluded pulmonary tuberculosis and identified A. xylosoxidans. We performed antibiotic sensitivity testing and treated the patient with a 6-week course of amoxicillin/clavulanate. After 2 months, follow-up chest CT revealed complete resolution of the cavitary lesion.
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Citations
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Case Report
- Pulmonary and Respiratory Medicine
- Partial spontaneous remission of small cell lung carcinoma with neurologic symptom
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Kyung Hyun Yun, Sung Heon Song, Chung Hyoun Kim, Chan Hee Hwang, Jun Ho Lee, Je Hyoung Choi, Sun Young Kim
- Yeungnam Univ J Med. 2017;34(2):275-278. Published online December 31, 2017
- DOI: https://doi.org/10.12701/yujm.2017.34.2.275
- 3,996 View
- 14 Download
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Abstract
PDF
- Small cell lung carcinoma (SCLC) is a cancer that shows aggressive behavior, early spread to distant sites, and frequent association with distinct paraneoplastic syndromes. Spontaneous remission of cancer, particularly of SCLC, is a rare biological event. Cases involving spontaneous regression of SCLC were reported, and were associated with paraneoplastic syndromes of the nervous system. This article reports on a 78-year-old man with SCLC in remission, with neurological symptoms. The patient visited the hospital because of generalized weakness, and imaging studies revealed a mass in the lower lobe of the left lung, pathological evaluation showed SCLC. The patient refused oncologic treatment and was treated only with conservative care. In follow-up study the diameter of the mass had decreased from initial 32 mm, 9 months after admission to 20 mm, 17 months after admission to 13 mm. The patient kept complaining of generalized weakness, dizziness, and paresthesia of limbs. We assumed that, in this case, the spontaneous remission of lung cancer was related to the immunologic response directed against the tumor, which is believed to be an important factor in the pathogenesis of paraneoplastic neurologic syndromes.
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