Journal of Yeungnam Medical Science

Evaluation of The Neck Mass.: Kei Won Song, Seok Keun Yoon, Byung Heun Choi; Yeungnam Univ J Med. 1986;3(1):1-11. Published online December 31, 1986; DOI: https://doi.org/10.12701/yujm.1986.3.1.1

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Abstract PDF: As public awareness of the various warning signs of malignancy increases, so does the concern evoked by the self identified finding of mass in the head and neck area. Not all the palpable masses are always significantly abnormal, but any nontender mass especially to the adult is significant enough to warrant further full investigation and follow up, the object of which should be to determine the possibility of malignancy and urgency of treatment. Approach to the diagnosis of the neck mass is so important in that it affects decision regarding further evaluation would lead to the determination of the most efficacious mode of therapy, eventually to the good prognosis. So, it should be emphasized that approach to the diagnosis of neck mass should be planned, systematic and thorough, this begins with the taking careful history following performance of complete examination of the head and neck especially to the nasopharynx, tongue base, pyriform sinus, palatine tonsil and larynx. Then a number of laboratory and radiologic studies are available, following triple endoscopy under general anesthesia and blind biopsy if needed. The most important rule to keep is that any biopsy procedures should be delayed to the last modality of effort to the diagnosis and if it should be done, under the plan of radical neck dissection.

Anesthetic Management for Patients with Increased Intracranial Pressure.: Heung Dae Kim; Yeungnam Univ J Med. 1986;3(1):13-24. Published online December 31, 1986; DOI: https://doi.org/10.12701/yujm.1986.3.1.13

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Abstract PDF: No abstract available.

Toxic-Shock Syndrome Toxin in Staphylococcus aureus.: Sung Kwang Kim, Jae Kyu Chung; Yeungnam Univ J Med. 1986;3(1):25-31. Published online December 31, 1986; DOI: https://doi.org/10.12701/yujm.1986.3.1.25

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Abstract PDF: No abstract available.

Histopathological Study of Carcinoma of the Colorectum in the Taegu Area.: Hae Joo Nam, Won Hee Choi, Tae Sook Lee, Suk Jae Hong; Yeungnam Univ J Med. 1986;3(1):33-39. Published online December 31, 1986; DOI: https://doi.org/10.12701/yujm.1986.3.1.33

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Abstract PDF: A clinical and statistical study was done for 123 patients with histologically proven colorectal malignant tumor from 1983 to 1986 at the department of anatomical pathology. Yeungnam University Hospital. The results were as follows: 1. Ratio between male and female was 1.6:1 and incidence was most prevalent in 7th decades comprising 29.3%. 2. Location of tumor was the most frequent in rectum (65%). 3. Frequent symptoms and signs in case of right colon were pain, abdominal mass and bowel habit change. In left colon, they were pain, bowel habit change and bloody stool or melena. In rectum, they were bloody stool or melena, bowel habit change and pain. 4. Duration of symptom was 1 to 3 months (33.3%). 5. The most frequent histological type was adenocarcinoma (82.9%). 6. According to Duke's classification, 32.9% of the tumor were stage C2. 7. Operative procedures were Mile's operation (47.0%), right hemicolectomy (19.8%), and lower anterior resection (11.7%). 8. Polyps were the most frequent associated disease. 9. The most common complication was wound infection (11.1%).

Purification of Band 3 from the Human Erythrocyte Membrane and its Incorporation into Liposome.: Jae Ryong Kim, Jung Hye Kim, Ki Yung Lee; Yeungnam Univ J Med. 1986;3(1):41-48. Published online December 31, 1986; DOI: https://doi.org/10.12701/yujm.1986.3.1.41

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Abstract PDF: Band 3, the predominant 95,000 dalton anion transport protein, is the major intrinsic glycoprotein of the human erythrocyte membrane. This anion carrier exists as a dimer and binds the cytoskeletons such as spectrin, ankyrin and actin. And the liposomes are vesicular structures which form spontaneously upon hydration of phospholipids. These artificial lipid vesicles have been investigated as model of the biological membranes and as a mean of improving the delivery of nucleic acids, drugs, proteins and biological substances to specific target tissues and cells. In this study, we were purified Band 3 from the human erythrocyte membrane (ghost) was prepared by hemolysis of intact human erythrocyte with weak alkali-hypotonic solution. Band 6 was removed from ghost by extracting with solution of an ionic strength of 0.15. Band 3 and Band 4 were solubilized selectively by extracting Band 6-depleted ghosts with Triton X-100 under nondenaturing conditions. Band 3 was then purified from Triton X-100 extract treated with p-chloromercuribenzoate by sucrose density gradient ultracentrifugation. This purified Band 3 was incorporated into liposomes prepared by reverse-phase evaporation. Phosphatidyl L-serine and cholesterol (1:1 molar ratio) were dissolved in chloroform and the chloroform was removed by rotator evaporation under reduced pressure. Band 3 solution without Triton X-100 was introduced into a mixture of lipids and diethylether. Diethylether was subsequently removed by evaporation. This purified Band 3 and its incorporation into liposomes were confirmed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.

A Clinical Study of Succinylcholine-Atracurium for Cesarian Section.: Dae Pal Park; Yeungnam Univ J Med. 1986;3(1):49-51. Published online December 31, 1986; DOI: https://doi.org/10.12701/yujm.1986.3.1.49

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Abstract PDF: Atracurium was used in 10 parturients undergoing elective cesarian section under general Anesthesia. An initial bolus of 0.4 mg/kg of the atracurium was injected after recovery from succinylcholine block. Complete neuromuscular block resulted in all cases. Muscular relaxation was maintained by incremental dose of 0.2mg/kg of atracurium. Administration of atracurium did not cause significant change in blood pressure, pulse rate and infants Apgar score. The residual neuromuscular block could be antagonized at the end of the procedure by mixture of 0.005 mg/kg glycopyrrolate and 0.03 mg/kg of neostigmine. In all parturients, antagonism was adequate as evidenced by respiratory response and head lift test. Atracurium may be advantageous in parturients undergoing cesarian section under general anesthesia cause it maintained cardiovascular stability, is non-cumulative, is readily antagonized by neostigmine and has no deleterious effect on the newborn.

The Application and Effect of the Brown-Roberts-Wells Stereotactic System in the Management of Intracranial Lesions.: Choong Bae Moon, Wan Shup Kim, Sam Kyu Ko, Jowa Hyuk Ihm, Seung Chan Baek, Yung Chul Chi, Byung Yearn Choi, Soo Ho Cho; Yeungnam Univ J Med. 1986;3(1):53-62. Published online December 31, 1986; DOI: https://doi.org/10.12701/yujm.1986.3.1.53

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Abstract PDF: In the past 10 years, modern technology has made deep seated obscure lesions visible. With development of computer technology and various stereotaxic techniques, many new procedures, refinement of old procedures, and development of new applications are possible. The authors are intended to provide a detailed description of our experience with the Brown-Roberts-Wells (BRW) stereotactic system in the evaluation and management of 90 patients with intracranial lesions, and to provide cases presentation of various inaccessible intracranial lesions.

Clinical Evaluation of Cesarian Section Anerohesia.: Dae Pal Park; Yeungnam Univ J Med. 1986;3(1):63-66. Published online December 31, 1986; DOI: https://doi.org/10.12701/yujm.1986.3.1.63

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Abstract PDF: Maternal and fetal effects of anesthesia for 423 cesarian section, performed during the past three and quarter years period in this hospital, have been evaluated. It is emphasized that the selection of anesthetic agent and method should depend upon the physical status of the patients and the ability of both obstetrician and anesthesiologists. Author results were as follows: 1. The incidence of c-section was 13.9% of total deliveries. 2. More than about three fourths of total cases were emergency cases. 3. Almost all cases were operated under general anesthesia. 4. The good physical states of patients resulted in better Apgar score of infants. 5. The shorter the interval from induction of anesthesia to delivery, the better was the Apgar score of infants.

A Clinical Use of CT Scan in Rectal Cancer.: Bo Yang Suh, Yong Sik Chung, Su Jeung Lee, Min Chul Shim, Koing Bo Kwun; Yeungnam Univ J Med. 1986;3(1):67-72. Published online December 31, 1986; DOI: https://doi.org/10.12701/yujm.1986.3.1.67

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Abstract PDF: Authors evaluated the accuracy of preoperative pelvic CT scan staging and its effects on management in 12 biopsy proved rectal cancer patients. Authors also studied postoperative CT in 5 patients to detect disease recurrence and metastasis. Preoperative CT staging was identical to surgical and/or pathological staging in 9 patients (75%), but it was underestimated in two cases and overestimated in one instance than in surgical stagings. In 7 cases, CT scan did not alter original choice of procedures. However, preoperative CT staging gave definitive informations to change management plans in 5 cases otherwise the treatment would be difficult and inadequate. Postoperative CT showed local recurrence in one and liver metastases in 2 cases. One of them was not detected at exploratory laparotomy.

Hemoglobin Concentration in Female Workers of Occupational Exposure to Lead.: Nan Kyu Park, Pock Soo Kang, Jong Hak Chung; Yeungnam Univ J Med. 1986;3(1):73-79. Published online December 31, 1986; DOI: https://doi.org/10.12701/yujm.1986.3.1.73

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Abstract PDF: This study was conducted to evaluate the effects of lead on the incidence of anemia and to find cases with lead poisoning early among female workers who have been exposed to lead occupationally, for one year from August, 1985. The level of blood lead and hemoglobin concentration were observed for 284 female lead workers and 123 female non-lead workers of industries in the Gumi industrial complex in Kyungpook Province. The average age was 20.3±2.9 years and 21.1±3.5 years in lead workers and non-lead workers, respectively. The average working duration was 26.46±19.26 months in lead workers. The mean value of blood lead was 30.11±6.61 µg/100 ml and 21.86±3.75 µg/100 ml in lead workers and non-lead workers, respectively. There were significant differences between two groups. The mean value of hemoglobin concentration was 14.00±0.57 g/100 ml and 14.03±0.64 g/100 ml in lead workers and non-lead workers, respectively. Anemia cases were not observed at Hb concentration below 12g/100 ml. The percentages of lead workers at Hb concentration ranged 12.0~13.0 g/100 ml were 4.5%. There was no dose-response relationship between blood lead level and the incidence of anemia. There were no remarkable differences between age and blood lead level as well as Hb concentration, and between working duration and the level of blood lead and hemoglobin.

Statistic Evaluation of Changing Pattern of Blood Pressure and Pulse Rate During Enflurane Anesthesia.: Ill Sock Suh, Dae Pal Park; Yeungnam Univ J Med. 1986;3(1):81-85. Published online December 31, 1986; DOI: https://doi.org/10.12701/yujm.1986.3.1.81

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Abstract PDF: Observation of changing pattern of blood pressure and pulse rate of enflurane anesthesia for 200 cases operations, performed during the past 4 years (1983~1986) in Yeungnam University Hospital have been evaluated clinically. In order to observe the influence of enflurane upon the blood pressure and pulse rate during general anesthesia, the authors prepared a formula, expressing changing of blood pressure and pulse rate by time series and analyzed the types and distribution pattern in the experiment. The results obtained were as follows: 1. Blood pressure and pulse rate were increased at the time of intubation. 2. Generally, blood pressure and pulse rate were increased at the time of intubation and then stabilized within 20 minutes. 3. Most common patterns were identified. ADEE type was 73~74%, which is most common type and AEEE type was about 40%.

Clinical Study of Empyema Thoracis.: Tae Nyeun Kim, Young Hyun Lee, Jae Chun Chung, Chong Suhl Kim; Yeungnam Univ J Med. 1986;3(1):87-94. Published online December 31, 1986; DOI: https://doi.org/10.12701/yujm.1986.3.1.87

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Abstract PDF

Empyema thoracis following pneumonia, intra-abdominal pathology, trauma, and surgical procedure continues to be a source of major morbidity and mortality. Thirty seven adult and eleven pediatric patients with empyema thoracis were treated at the University of Yeungnam Medical Center from May 1983 to November 1986. Age distribution ranged from 6 months to 72 years and showed a double-peaked curve with the highest incidence between 36 and 65 years and below 15 years of age. There were male predominance in patients above 16 years of age. The most common predisposing factors was impaired consciousness due to either alcoholism or head injury. The causes of empyema were as follows: pneumonia 64.6%, ling abscess 6.4%, intraabdominal pathology 6.4%, and surgical procedure 6.4%. The cardinal symptoms were fever, cough, chest pain, dyspnea, sputum, weight loss, anorexia, and night sweat in orders. Culture of empyema fluid were positive in 50% of patients. The isolated organisms were Gram-negative bacilli 33.3%, staphylococcus aureus 25%, and streptococcus 25%. The patients received antibiotics in conjunction with various invasive procedures: chest tube drainage 77.1%, decortications 6.3%, and repeated thoracentesis 10.3%. There were 4 deaths, 1 child and 3 adults, with an overall mortality of 8.3%.

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Empyema caused byClostridium perfringens
Hyun-Sun Park, Chul-Min Jung, Jang-Won Choi, Yoonki Hong, Woo Jin Kim
Yeungnam University Journal of Medicine.2015; 32(1): 35. CrossRef

Radiologic Analysis of Tuberculous Spondylitis.: Mi Soo Hwang, Sun Yong Kim; Yeungnam Univ J Med. 1986;3(1):95-102. Published online December 31, 1986; DOI: https://doi.org/10.12701/yujm.1986.3.1.95

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Abstract PDF: Among the skeletal tuberculous spondylitis is high incidence and curable disease, if early diagnosis and treatment are possible. We reviewed clinical manifestations and radiologic analysis of 30 cases tuberculous spondylitis from May 1983 to Sept. 1986, at Yeungnam medical center, Yeungnam University. The results were follows: 1. The frequent involve sites were thoracolumbar vertebra. 2. The continuous lesion is 86.7% of the all cases. 3. The most common type was intervertebral type, and lytic and sclerotic lesion were same incidence. 4. Paravertebral abscess, kyphosis and disc space narrowing were demonstrated more than 80.0% of the cases. 5. Computed tomography was more accurate diagnostic method rather than conventional plain study to evaluation of extent of lesion, involvement of spinal canal and cord, and size and location of paravertebral abscess. And CT guided abscess drainage procedure was helpful to diagnosis and treatment. 6. Ultrasonography was helpful to differential diagnosis between paravertebral abscess and other solid mass, and useful to follow up study of paravertebral abscess after treatment.

Production of Monoclonal Antibody to Polychlorinated Biphenyl Induced Cytochrome P-450 LMII in Rat Liver.: Jung Hye Kim, Jae Ryong Kim, Ki Yung Lee; Yeungnam Univ J Med. 1986;3(1):103-110. Published online December 31, 1986; DOI: https://doi.org/10.12701/yujm.1986.3.1.103

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Abstract PDF: Cytochrome P-450 (CP-450) is one of the three components of the liver microsomal enzyme system which hydroxylates fatty acids, hydrocarbons and a variety of drugs and other foreign compounds. Female Balb/c mice were immunized with purified polychlorinated biphenyl (PCB) – induced CP-450 LMII. The spleen cells derived from immunized mice were fused with SP2 myeloma cells using polyethylene glycol (PEG 3500). The hybrid cells were selected by hypoxanthine-aminopterin-thymidine (HAT) medium and the culture fluid were screened by enzyme-linked immunosorbent assay to CP450 LMII. The hybrid cells(×107) were inoculated into intraperitoneal cavity of Balb/c mice for the purpose of production of ascetic fluids. Monoclonal antibody (Mab) was purified from ascitic fluid by DEAE cellulose ion exchange chromatography and I¹²⁵ labeled Mab was also confirmed by autoradiography and SDS-polyacrylamide gel electrophoresis (MW:55,000 and 110,000)

A Study on Organic Brain Syndrome in the Elderly at the Home for the Aged.: Byung Tak Park, Jin Sung Kim, Seung Douk Cheung; Yeungnam Univ J Med. 1986;3(1):111-120. Published online December 31, 1986; DOI: https://doi.org/10.12701/yujm.1986.3.1.111

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Abstract PDF: The authors studied organic brain syndrome, using organic brain syndrome scale of the Diagnostic Interview Schedule for DSM-Ⅲ, in the subjects of 65 males and 231 females at the homes for the aged in the Taegu and Kyong-buk areas. The authors collected the data during the period from June to August, 1986, and applied ANOVA and x²-test in order to compare various psychologic factors in relation to the organic brain syndrome. The results could be summarized as follows: The elderly males (15%) showed high OBS scores of 12 and over, while ninety elderly females (39%) showed the same scores. Among those psychosocial factors, age, education, birth place, occupation, religion, history before institutionalization are significantly related to the OBS scores.

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