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Young Jo Kim 34 Articles
Bronchogenic cyst masquerading as malignant pericardial effusion with tamponade
Kang Un Choi, Byung Jun Kim, Hong Ju Kim, Jang Won Son, Jong Seon Park, Dong Gu Shin, Young Jo Kim
Yeungnam Univ J Med. 2017;34(1):91-95.   Published online June 30, 2017
DOI: https://doi.org/10.12701/yujm.2017.34.1.91
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AbstractAbstract PDF
We report on a rare case involving a 23-year-old female patient with mediastinal cystic mass complicated with acute pericarditis and cardiac tamponade. Pericardial fluid demonstrated lymphocyte-predominant exudate and the level of carcinoembryonic antigen (CEA) was unexpectedly elevated. Successive aspiration of mediastinal cystic mass revealed a very high level of CEA (>100,000 U/mL) and carbohydrate antigen 19-9 (>15,000 ng/mL). This patient was clinically diagnosed as an infected bronchogenic cyst complicated with pericarditis and cardiac tamponade. The treatment resulted in alleviation of her symptoms.
Parasympathetic Modulation Plays a Key Role in Initiation of Paroxysmal Atrial Fibrillation.
Won Jae Lee, Dong Gu Shin, Geu Ru Hong, Jong Sun Park, Young Jo Kim
Yeungnam Univ J Med. 2007;24(2):216-231.   Published online December 31, 2007
DOI: https://doi.org/10.12701/yujm.2007.24.2.216
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AbstractAbstract PDF
BACKGROUND
An acceleration or deceleration of the heart rate (HR), which reflects autonomic effects, is observed before the onset of paroxysmal atrial fibrillation (PAF). The purpose of this study was to assess the discrepancy in the autonomic interactions before the onset of PAF for different patterns of change in the HR. MATERIALS AND METHODS: From 105 Holter tapes with the PAF recorded, 55 episodes (42 patients, 34 men, 58+/-12 years) of PAF (>5 min), preceded by a sinus rhythm for more than 1 hour, were selected and submitted to time-domain and frequency-domain HR variability analyses. Fifty-five episodes were divided into 2 groups: group A PAF (n=30) with acceleration of the HR during the last 2 minutes before the PAF and group B (n=25) with deceleration of the HR. RESULTS: A significant linear decrease in the mean R-R interval was observed in group A (924+/-30 to 835+/-28 ms, P=0.001) and an increase from 831+/-32 to 866+/-31 ms in group B PAF episodes (P=0.046). In the frequency-domain analyses, the LF/HF ratio exhibited a progressive linear increase before the PAF in group A (P=0.005). The HF normalized units (HFnu) and natural logarithm-transformed HF (lnHF) values decreased from 30.8+/-4.0 to 16.1+/-1.8 (P=0.003) and 4.49+/-0.25 to 4.07+/-0.22 (P=0.001), respectively. Contrary to the results in group A, a significant increase in the HF components (HFnu and lnHF) (from 22.6+/-3.2 to 30.2+/-4.0, P=0.005, and 4.27+/-0.27 to 4.75 0.33, P=0.001, respectively) and a resultant decrease in the LF/HF ratio were observed in group B PAF episodes. No significant changes were observed in the LF components in either PAF group. CONCLUSION: Autonomic stimuli leading to an acceleration or deceleration of the HR before the onset of AF are due to parasympathetic modulation. Parasympathetic modulation plays a key role in the initiation of PAF
The Difference of Left Atrial Volume Index: Can It Predict the Occurrence of Atrial Fibrillation after Radiofrequency Ablation of Atrial Flutter?.
Ung Kim, Young Jo Kim, Sang Wook Kang, In Wook Song, Jung Hwan Jo, Sang Hee Lee, Geu Ru Hong, Jong Seon Park, Dong Gu Shin
Yeungnam Univ J Med. 2007;24(2):197-205.   Published online December 31, 2007
DOI: https://doi.org/10.12701/yujm.2007.24.2.197
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AbstractAbstract PDF
BACKGROUND
The occurrence of atrial fibrillation after ablation of atrial flutter is clinically important. We investigated variables predicting this evolution in ablated patients without a previous atrial fibrillation history. MATERIALS AND METHODS: Thirty-six patients (Male=28) who were diagnosed as atrial flutter without previous atrial fibrillation history were enrolled in this study. Group 1 (n=11) was defined as those who developed atrial fibrillation after atrial flutter ablation during 1 year follow-up. Group 2 (n=25) was defined as those who has not occurred atrial fibrillation during same follow-up term. Echocardiogram was performed to all patients. We measured left atrial size, left ventricle end diastolic and systolic dimension, ejection fraction and left atrial volume index before and after ablation of atrial flutter. The differences of each variables were compared and analyzed between two groups. RESULTS: The preablation left ventricular ejection fraction (preLVEF) and postablation left ventricular ejection fraction (postLVEF) are 54+/-14%, 56+/-13% in group 1 and 47+/-16%, 52+/-13% in group 2. The differences between each two groups are statistically insignificant (2.2+/-1.5 in group 1 vs 5.4+/-9.8 in group 2, p=0.53). The preablation left atrial size (preLA) and postablation left atrial size (postLA) are 40+/-4 mm, 41+/-4 mm in group1 and 44+/-8 mm, 41+/-4 mm in group 2. The atrial sizes of both groups were increased but, the differences of left atrial size between two groups before and after flutter ablation were statistically insignificant (0.6+/-0.9mm in group 1 vs -3.8+/-7.4 mm in group 2, p=0.149). The left atrial volume index before flutter ablation was significantly reduced in group 1 than group 2 (32+/-10 mm3/m2, 35+/-10 mm3/m2 in group 1 and 32+/-10 mm3/m2, 29+/-8 mm3/m2 in group 2, p<0.05). CONCLUSION: The difference between left atrial volume index before and after atrial flutter ablation is the robust predictor of occurrence of atrial fibrillation after atrial flutter ablation without previous atrial fibrillation.
Treatment of Coronary Artery Perforation and Tamponade Complicating Balloon Angioplasty by PTFE-Covered Stent. A Case Report.
Jong Seon Park, Gu Ru Hong, Jun Ho Bae, Ihn Ho Cho, Bong Sup Shim, Young Jo Kim, Dong Gu Shin
Yeungnam Univ J Med. 2005;22(1):90-95.   Published online June 30, 2005
DOI: https://doi.org/10.12701/yujm.2005.22.1.90
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AbstractAbstract PDF
A coronary artery perforation is a rare but often fatal complication of angioplasty. We experienced a coronary artery perforation and cardiac tamponade during balloon angioplasty. A polytetrafluorethylene (PTFE) -covered stent was used to successfully close the perforation.
Evaluation of short-term Hypolipidemic Effect and Safety of Simvastatin(Zocor(R)) in Patients with Hyperlipidemia.
Min Kyoung Kim, Yong Ho Park, Jong sun Park, Dong Gu Shin, Young Jo Kim, Gi Sik Kim
Yeungnam Univ J Med. 2003;20(2):152-159.   Published online December 31, 2003
DOI: https://doi.org/10.12701/yujm.2003.20.2.152
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AbstractAbstract PDF
BACKGROUND
Hyperlipidemia is the one of the major risk factors causing the atherosclerosis of coronary arteries. Treatment of hyperlipidemia with drugs has been confirmed the effects of therapy showing a decreased incidence of coronary artery disease. Simvastatin is a new drug of HMG-CoA reductase inhibitors and the short-term hypolipidemic effects and safety of simvastatin is evaluated in patients with hyperlipidemia. METHODS: We studied 63 patients (39 males and 24 females, mean age 58) for 12 weeks whose plasma levels of total cholesterol were higher than 240 mg/dL or higher than 220 mg/dL with ischemic heart disease. Simvastatin was administered 20 mg/day and measured lipid profile at 12 week interval. RESULT: 1)Simvastatin significantly reduced the level of the plasma total cholesterol(-29.3%), LDL- cholesterol(-36.9%) and triglyceride(-13%)(p<0.05) but the level of HDL-cholesterol was not changed after 12 weeks simvastatin therapy. 2)the clinical symptoms and laboratory examination before and after simvastatin treatment showed no particular abnormal findings in short term follow up. CONCLUSION: These results suggested that short-term simvastatin therapy in patients with hyperlipidemia seeems to be very effective and safe.

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  • A Population Pharmacokinetic–Pharmacodynamic Model for Simvastatin that Predicts Low‐Density Lipoprotein‐Cholesterol Reduction in Patients with Primary Hyperlipidaemia
    Jimyon Kim, Byung‐Jin Ahn, Hong‐Seok Chae, Seunghoon Han, Kichan Doh, Jeongeun Choi, Yong K. Jun, Yong W. Lee, Dong‐Seok Yim
    Basic & Clinical Pharmacology & Toxicology.2011; 109(3): 156.     CrossRef
P wave dispersion as a predictor of idiopathic paroxysmal atrial fibrillation.
Gue Ru Hong, Woong Kim, Jong Seon Park, Dong Gu Shin, Young Jo Kim, Bong Sup Shim
Yeungnam Univ J Med. 2001;18(2):267-276.   Published online December 31, 2001
DOI: https://doi.org/10.12701/yujm.2001.18.2.267
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AbstractAbstract PDF
BACKGROUND
P wave dispersion(PWD) is defined as the difference between the maximum and minimal P wave duration in any of the 12 leads of the surface ECG. The prolongation of atrial conduction time and the inhomogeneous propagation of sinus impulse are known electrophysiologic features in patients with paroxysmal atrial fibrillation(PAF). The purpose of this study was to determine the role of P wave dispersion for the prediction of PAF and to evaluate the effectiveness of prophylactic antiarrhythmic therapy. MATERIALS AND METHODS: The study population included 20 patients with a history of idiopathic PAF and 20 age and sex matched healthy control subjects. We measured the maximum P wave duration(P maximum) and P wave dispersion from 12 lead ECG. RESULTS: P maximum and P dispersion in idiopathic PAF were significantly higher than normal control group(97.2+/-12, 48.5+/-9msec vs, 76.5+/-11, 21+/-8msec, respectively p<0.001, <0.001). After 12-month follow up period P maximum and P dispersion were significantly reduced than those of initial state(77.2+/-13, 26.4+/-9msec vs. 97.2+/-12, 48.5+/-9msec, respectively p<0.001,<0.001). CONCLUSION: P dispersion and P maximum were significantly different between patients with idiopathic PAF and healthy control group. Those are easily accessible, non-invasive simple electrocadiographic markers that could be used for the prediction and prognostic factors of idiopathic PAF.
Change of Serum Levels of C-Reactive Protein After Coronary Angioplasty and Its Effects on Clinical Restenosis.
Jong Seon Park, Gu Ru Hong, Chae Hoon Lee, Dong Gu Shin, Young Jo Kim, Bong Sup Shim
Yeungnam Univ J Med. 2001;18(2):215-225.   Published online December 31, 2001
DOI: https://doi.org/10.12701/yujm.2001.18.2.215
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AbstractAbstract PDF
BACKGROUND
There are many evidences that inflammation is an important determinant of the development of atherosclerosis and one of the systemic markers of inflammation, C-reactive protein(CRP), is associated with extent of coronary artery disease and risk of coronary events. We assessed the time response of CRP response after coronary angioplasty and it's influence on the clinical restenosis in angina patients. MATERIALS AND METHODS: Patients included 36 angina patients undergoing single vessel angioplasty. Levels of CRP were measured before and 12, 24, 48, and 72 hours after angioplasty. Clinical restenosis was assessed at 6 months after procedure. RESULTS: Baseline CRP level was 0.30+/-0.01 mg/dL in stable and 0.46+/-0.28 mg/dL in unstable angina patients(p<0.05). After angioplasty, CRP level was increased with peak at 24 hour and persisted to 72 hours after angioplasty. At 24 hour after angioplasty, the magnitude of CRP change was 0.32+/-0.31 mg/dL in stable and 0.79+/-0.73 mg/dL in unstable angina patient(p<0.05). The change of CRP level was not associated with troponin-T after angioplasty. In unstable angina patients, clinical restenosis was developed in 8% of patients with low baseline CRP levels and in 50% of those with high baseline CRP levels more than 0.6 mg/dL(p<0.05). CONCLUSION: In unstable angina patients, inflammatory response is more increased than stable angina patients, and increased inflammatory response effects on the restenosis after coronary angioplasty.
Development of Data Acquisition System for Quantification of Autonomic Nervous System Activity and It's Clinic Use.
Dong Gu Shin, Jong Sun Park, Young Jo Kim, Bong Sup Shim, Sang Hak Lee, Jun Ha Lee
Yeungnam Univ J Med. 2001;18(1):39-50.   Published online June 30, 2001
DOI: https://doi.org/10.12701/yujm.2001.18.1.39
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AbstractAbstract PDF
BACKGROUND
Power spectrum analysis method is a powerful noninvasive tool for quantifying autonomic nervous system activity. In this paper, we developed a data acquistion system for estimating the activity of the autonomic nervous system by the analysis of heart rate and respiratory rate variability using power spectrum analysis. MATERIALS AND METHODS: For the detection of QRS peak and measurement of respiratory rate from patient's ECG, we used low-pass filter and impedence method respectively. This system adopt an isolated power for patient's safety. In this system, two output signnals can be obtained: R-R interval(heart rate) and respiration rate time series. Experimental ranges are 30-240 BPM for ECG and 15-80 BPM for respiration. RESULTS: The system can acquire two signals accurately both in the experimental test using simulator and in real clinical setting. CONCLUSION: The system developed in this paper if efficient for the acquisition of heart rate and respiration signals. The system will play a role in research area for improving our understanding of the pathophysiologic involvement of the autonomic nervous system in various disease states.
Primary Cardiac Lymphoma: Case Report.
Jun Ho Bae, Jong Suk Lee, Hyung Jun Kim, Min Kyung Kim, Young Ho Park, Gue Ru Hong, Jong Sun Park, Dong Gu Sin, Young Jo Kim, Bong Sup Sim
Yeungnam Univ J Med. 2000;17(1):82-86.   Published online June 30, 2000
DOI: https://doi.org/10.12701/yujm.2000.17.1.82
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AbstractAbstract PDF
Primary cardiac lymphoma defined as involving only the heart and pericardium, is very rare and is diagnosed predominantly late in the course of illness or autopsy. This tumor is commonly fatal and until recently were rarely diagnosed antemortem. Recently, it was reported in patients with acquired immunodeficiency syndrome. We report a case of primary cardiac lymphoma in a 56 year old female who showed progressive exertional dyspnea. On echocardiogram and CT scan, large ill defined mass was demonstrated in right atrial and ventricular wall. It was diagnosed as B-cell type lymphoma on open cardiac biopsy.
The Predictors of Cerebral infarction in Mitral Stenosis.
Hyung Jun Kim, Woong Kim, Jong suk Lee, Gue Ru Hong, Jong Seon Park, Dong Gu Sin, Young Jo Kim, Bong Sup Shim
Yeungnam Univ J Med. 2000;17(1):75-81.   Published online June 30, 2000
DOI: https://doi.org/10.12701/yujm.2000.17.1.75
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AbstractAbstract PDF
BACKGROUND
Systemic embolism especially, cerebral infarction is one of the most important complications in patients with mitral stenosis. The authors analyse the some that could predict the development of cerebral infarction in cases of mitral stenosis and propose preventive therapeutic measures. METHODS: Retrospective study of 127 patients with rheumatic mitral stenosis was performed by analysis their medical records for transthoracic(TTE) or transesophageal echocardiography(TEE) over a 12months period. The patients were divided into two groups according to the presence (Group I: n=26, age: 55+/-13 years) or absence (Group II: n=101, age: 48.5+/-13 years) of cerebral infarction. No significant difference was observed between the two groups with respect to sex and functional class. RESULTS: Patients of group I were older (55.0+/-13 vs 48.5+/-13;p<0.05), had more dilated left atrial size(5.10+/-0.48 vs 4.81+/-0.70;p<0.05) and smaller mitral surface area(1.01+/-0.39 vs 1.21+/-0.45;p<0.05). In Group I, the incidence of atrial fibrillation(22 out of 26 vs 57 out of 101;p<0.05) and spontaneous left intra-atrial contrast phenomenon(22 out of 26 vs 44 out of 101;p<0.05) was more frequently observed. On multivariate analysis, atrial fibrillation and anticoagulant therapy were the independent predictive factors. CONCLUSION: Age, left atrial dilatation, the severity of mitral stenosis, the presence of spontaneous contrast and especially the presence of atrial fibrillation are the main predictive factors of the development of cerebral infarction in mitral stenosis. Patients presenting one or several of these factors may benefit from prophylactic anticoagulant treatment.
The Effect of Early IABP and Reperfusion therapy in Patient of Post MI Cardiogenic shock.
Jong Suk Lee, Min Kyeung Kim, Woong Kim, Hyung Jun Kim, Jun Ho Bae, Jong Seon Park, Dong Gu Sin, Young Jo Kim, Bong Sup Shim
Yeungnam Univ J Med. 2000;17(1):31-38.   Published online June 30, 2000
DOI: https://doi.org/10.12701/yujm.2000.17.1.31
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AbstractAbstract PDF
BACKGROUND
We sought to examine the use and outcomes with early intraaortic balloon couterpulsation(IABP) combined early reperfusion therapy in patients presenting with cardiogenic shock complicating acute myocardial infarction. The use of IABP in patients with cardiogenic shock is widely accepted. however, there is a paucity of information on the use of this technique in patients with cardiogenic shock who are treated with reperfusion therapy in Korea. MATERIALS AND METHODS: Twenty-eight Patients presented with cardiogenic shock were classified into two groups: the early IABP group (insertion within 12 hours after AMI onset time) and late IABP group (insertion after 12 hours). We compared In-hospital mortality in two group (early IABP group vs late IABP group). RESULTS: Two groups show no significant difference at clinical feature and coronary angiographic results. Among total 28 patients, 7 patients were treated with thrombolytic therapy and 21 patients with PTCA. Insertion site bleeding, fever, thrombocytopenia were reported as some of the complications of IABP insertion. In-hospital mortality of early IABP group and late IABP group were 4 patients(25%) and 8 patients(66%), respectively(p<0.05). Early IABP insertion and early PTCA showed lower hospital mortality rates. There was significant difference in the time to PTCA after AMI onset between the to groups(p<0.05). CONCLUSION: IABP appears to be useful in patients presenting with cardiogenic shock unresponsive medical therapy. Early IABP insertion and early Reperfusion therapy may reduce In-hospital mortality rates in PostMI Cardiogenic shock patients.
Clinical Presentation of th patients with Non-traumatic Chest Pain in Emergency Department.
Jun Young Chung, Sam Beom Lee, Byung Soo Do, Jong Seon Park, Dong Gu Shin, Young Jo Kim
Yeungnam Univ J Med. 1999;16(2):283-295.   Published online December 31, 1999
DOI: https://doi.org/10.12701/yujm.1999.16.2.283
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AbstractAbstract PDF
BACKGROUND
Patients with acute non-traumatic chest pain are among the most challenging patients for care by emergency physicians, so the correct diagnosis and triage of patients with chest pain in the emergency department(ED) becomes important. To avoid discharging patients with acute myocardial infarction(AMI) without medical care, most emergency physicians attempt to admit almost all patients with acute chest pain and order many laboratory tests for the patients. But in practice, many patients with non-cardiac pain can be discharged with simple tests and treatment. These patients occupy expensive intensive care beds, substantially increasing financial cost and time of stay at ED for the diagnosis and treatment of myocardial ischemia and AMI. Despite vigorous efforts to identify patients with ischemic heart disease, approximately 2% to 5% of patients presented to the ED with AMI and chest pain are inadvertently discharged. If the cause for the chest pain is known, rapid and accurate diagnosis can be implemented, preventing wastes in time and money and inadvertent discharge. Methods and Results: The medical records of 488 patients from Jan. 1 to Dec. 31, 1997 were reviewed. There were 320(angina pectoris 140, AMI 128) cases of cardiac diseases, and 168(atypical chest pain 56, pneumothorax 47) cases of non-cardiac diseases. The number of associated symptoms were 1.1+/-0.9 in non-cardiac diseases, 1.4+/-1.1 in cardiac diseases and 1.7+/-1.1 in AMI(p<0.05). In laboratory finding the sensitivity of electrocardiography(EKG) was 96.1%, while the sensitivity of myoglobin test ranked 45.1%. Admission rate was 71.6% in for cardiac diseases and 50.6% for non-cardiac diseases(p<0.01). Mortality rate was 8.8% in all cases, 13.8% in cardiac diseases, 0.6% in non-cardiac diseases, and 28.1% especially in AMI. CONCLUSION: In conclusion, all emergency physicians should have thorough knowledge of the clinical characteristics of the diseases which cause non-traumatic chest pain, because a patient with any of these life-threatening diseases would require immediate treatment. Detailed history on the patient should be taken and physical examination performed. Then, the most simple diagnostic approach should be used to make an early diagnosis and to provide treatment.
Dual-Isotope SPECT Imaging with Thallium-201 and Technetium-99m MIBI in Detecting Coronary Artery Disease.
Gyu Gwang Lee, Ihn Ho Cho, Hyoung Woo Lee, Jong Sun Park, Kyu Chang Won, Dong Gu Sin, Young Jo Kim, Bong Sup Shim
Yeungnam Univ J Med. 1999;16(1):101-107.   Published online June 30, 1999
DOI: https://doi.org/10.12701/yujm.1999.16.1.101
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AbstractAbstract PDF
We evaluated the results of sequential SPECT dual-isotope imaging with Tl-201 and Tc-99m MIBI in 24 patients, all of whom also had coronary angiography within the past one month. Coronary angiography showed that 12 patients had no CAD, 4 patients had one-vessel CAD, 7 patients had two-vessel CAD and 1 patient had three-vessel CAD. Serial studies of resting Tl-201 and dipyridamole stress Tc-99m MIBI were completed within 2 hours. When more then 50% of coronary artery narrowing was considered significant. The overall sensitivity and specification of CAD detection were 91.7%. The sensitivity of CAD detection in patients with one-vessel and multi-vessel diseases was 75% and 100%, respectively. Therefore, sequential dual-isotope SPECT demonstrated high sensitivity and specificity of CAD detection. In conclusion, sequential dual-isotope imaging is feasible and can be completed in a short time and may therefore enhance laboratory throughput and patient convenience.
Antihypertensive effect and safety of imidapril on the patient with essential hypertension.
Gue Ru Hong, Jun Ho Bae, Dae Jin Jun, Jong Seon Park, Dong Gu Shin, Young Jo Kim, Bong Sup Sim
Yeungnam Univ J Med. 1999;16(1):69-75.   Published online June 30, 1999
DOI: https://doi.org/10.12701/yujm.1999.16.1.69
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AbstractAbstract PDF
Imidapril(Tanatril(R)), a newly developed ACE inhibitor, has been used to treat hypertension and congestive heart failure. This study was designed to assess the antihypertensive effect and safety of Imidapril(Tanatril(R)) in patient with essential hypertension. 5-10mg of imidapril(Tanatril(R)) was administered once day in 30 patients with essential hypertension and followed up to 8 weeks. We tested the drug's effectiveness, safety, and the incidence of imidapril induced dry coughs. After 8 weeks of treatment with Imidapril, 76.2%(16/21) of patient showed lowered blood pressure and 47.6% showed normal blood pressure. The overall incidence of adverse effects was 33.3%(7/21). and among these adverse effects. dry cough was shown in only 9.5%. Thus, concluded that imidapril(Tanatril(R)) is as safe and effective as other ACE inhibitors. especially with imidapril showing very little incidence of dry cough compared to other ACE inhibitors.
Determinants of Successful Percutaneous Transluminal Coronary Angioplasty.
Kyo Won Choi, Jun Young Kweon, Yeung Jin Kim, Tae Il Lee, Dong Gu Shin, Young Jo Kim, Bong Sup Shim, Hyun Woo Lee, Sam Beom Lee
Yeungnam Univ J Med. 1994;11(2):230-239.   Published online December 31, 1994
DOI: https://doi.org/10.12701/yujm.1994.11.2.230
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AbstractAbstract PDF
In Order to evaluate determinants of successful percutaneous transluminal coronary angioplasty (PTCA), PTCA was performed for 172 coronary arterial lesions in 120 patients(89 male, 31 female) at Yeungnam university hospital from Sep. 1992 to Aug 1993. The corinary artery luminal diameter at the site of the original stenosis was eveluated from end-diastolic frames of identical projections of the preangioplasty and immediate post angioplasty. The coronary luminal and balloon diameters were measured with using of computer measuring system. Overall success rate of 172 attempted lesions was 87.2%. Success rate of female patients was 93.5% and higher than those of male patients. According to the clinical diagnosis, success rate in stable angina was 93.7% and higher than those of post myocardial infarction angina, unstable angina and acute myocardial infarcrion. Success rate of American Heart Association type C lesion was 65.5% and lower those of type A(95.7%), type B (89.%). There was significantly difference in preangioplasty luminal stenosis, elastic recoil and length of lesion between successful PTCA group and failed PTCA group. Success rate of lesion location at a bed >45° and presence of intracoronary thrombus were lower than than those of other angiographic findings. In coclusion, primary angioplasty success was affected by specific angiographic factors, Stenosis severity, thrombus, lesion location at a bend >45°, elastic recoil, and length of lesion were the principle of determinants of coronary angioplasty success rate.
A Case of Amiodarone-induced Interstitial Lung Disease
Byeong Hun Kim, Won Jong Park, Jin Hong Chung, Kwan Ho Lee, Young Jo Kim, Bong Sup Shim, Hyun Woo Lee
Yeungnam Univ J Med. 1994;11(1):186-192.   Published online June 30, 1994
DOI: https://doi.org/10.12701/yujm.1994.11.1.186
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AbstractAbstract PDF
Amiodarone has a potent suppressive effect on supraventricular and ventricular dysrhythmias, so has widely used as a class III antiarrhythmic agent. However, significant side effects were noted in over 50% of patients treated. Pulmonary toxicity represents the most serious adverse reaction limiting the clinical efficacy of this new antidysrhythmic drug. A 66-year-old male had received amiodarone 200 mg/day for 7 months to control high grade ventricular premature contraction and was admitted due to dyspnea on exertion for 1 week. At the time of admission end-inspiratory crepitant rale was heard on auscultation. The roentgenogram of his chest revealed reticular and granular radiopaque densities on both lower lung fields and high resonance CT revealed interstitial fibrosis and pneumonic consolidations on the periphery of the both middle and lower lobes. Trans-bronchoscopic lung biopsy revealed non-specific interstitial fibrosis. The laboratory findings were non-specific. We present a case of amiodarone-induced interstitial pulmonary disease clinically improved by corticosteroid therapy
A Case of Disappearing Symptoms Developed Repetitively in a Complete Atrioventricular Block Patient Implanted Bipolar Permanent Pacemaker After Converting It into Unipolar System.
Jun Young Kweon, Kyo Won Choi, Dong Gu Shin, Young Jo Kim, Bong Sup Shim, Hyun Woo Lee
Yeungnam Univ J Med. 1994;11(1):181-185.   Published online June 30, 1994
DOI: https://doi.org/10.12701/yujm.1994.11.1.181
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AbstractAbstract PDF
Pacemaker malfunctions are secondary to alterations of the preset pacing rate, irregular pacing failure of sensing, failure of cardiac capture or depolarization, and various combinations of these events. A 76 years old male patients was admitted due to pacemaker malfunction. 2 years ago, he was diagnosed as complete atrioventricular block. And then bipolar permanent pacemaker was implanted. Since then syncopal attack developed repetitivly. 12 lead ECG and 24 hour holter moniter monitoring, revealed pacing and sensing failure, thus we converted bipolar system into unipolar system. since then syncopal attack did not developed again.
Analysis of Polar Maps of Dipyridamole Stress/Rest Tc-MIBI Myocardial SPECT in 14 Healthy Young Men.
Ihn Ho Cho, Dong Gu Shin, Hyoung Woo Lee, Young Jo Kim, Bong Sup Shim, Hyun Woo Lee
Yeungnam Univ J Med. 1994;11(1):146-152.   Published online June 30, 1994
DOI: https://doi.org/10.12701/yujm.1994.11.1.146
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AbstractAbstract PDF
We performed the same day dipyridamole stress/rest myocardial SPECT in 14 healthy young men, reconstructed the polar maps according to Cedars-Sinal method and quantitated the radioactivity of myocardial wall. We divided the whole myocardium to 9 sectors. The latero-anterior wall contains the highest count. The infero-septal wall contains the lowest count. There isn't any significant differences of radioactivity in each segment between stress and rest polar map. The hemodynamic parameters after dipyridamole injection in the subjects were significantly changed except systolic blood pressure : the heart rate was increased and diastolic blood pressure was decreased. Adverse effects were reported in 85.7%. We suggest that these data can be used to dectect perfusion defect in the coromary artery disease.
Prevalene of Secondary Hypertension in Yeungnam University Hospital.
Jun Young Kweon, Kyo Won Choi, Dong Gu Sin, Hyoung Woo Lee, Kyeung Woo Yu, Young Jo Kim, Bong Sup Shim, Hyun Woo Lee
Yeungnam Univ J Med. 1994;11(1):109-114.   Published online June 30, 1994
DOI: https://doi.org/10.12701/yujm.1994.11.1.109
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AbstractAbstract PDF
We studied the incidence and results of treatment of secondary hypertension in Yeungnam University Hospital. Nineteen hundred fifty patients with hypertension were included from march 1990 to march 1994. We analysed the prevalence of secondary hypertension and results of treatment. The incidence of secondary hypertension in Yeungnam University Hospital was six percent. The most common underlying causes of secondary hypertension was renal parenchymal disease. Patients with three forms of potentially reversible secondary hypertension, namely, renovascular hypertension, endocrine disease, exogenous hormone, were assed to determine whether surgery or withdrawal of the exogenous hormane had led to an improvement in blood pressure control. The incidence of secondary hypertension in Yeungnam University Hospital was low(6%), but some of these are curable. Thus it is very inportant that evaluate the secondary hypertension.
An aortic dissection in pregnant woman - a case report -.
Hyeong Min Lee, Eun Pyo Hong, Dong Hyup Lee, Jung Cheul Lee, Sung Sae Han, Dong Gu Sin, Young Jo Kim, Bong Sup Shim
Yeungnam Univ J Med. 1993;10(1):253-259.   Published online June 30, 1993
DOI: https://doi.org/10.12701/yujm.1993.10.1.253
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AbstractAbstract PDF
We have experienced a case of aortic dissecting aneurysm in pregnant woman. She felt initially severe chest pain which was radiated to the neck on the 3days before delivery. Thereafter dyspnea and generalized edema were developed for 1 month after delivery. She was diagnosed as aortic dissectLn, Debakey type-II. During cardiopulmonary bypass, the selective cerebral perfusion was done through the right and left commom carotid arteries. Aortic replacement with Hemashield vascular graft and reimplantation of innominate artery, resuspension of aortic valve, repair of intimal tear were performed. The postoperative course was uneventful.

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  • A Case of Ascending Aortic Dissection with Severe Aortic Regurgitation Diagnosed by Echocardiography
    Sung-Hee Kim, Ok-Kyoung Lee
    The Korean Journal of Clinical Laboratory Science.2020; 52(4): 425.     CrossRef
A case of free-floating left atrial ball thrombus in mitral stenosis.
Young Jin Kim, Tea Il Lee, Kyo Won Choi, Seung Ho Kang, Dong Gu Sin, Young Jo Kim, Bong Sup Shim, Hyun Woo Lee, Eun Pyo Hong
Yeungnam Univ J Med. 1993;10(1):237-244.   Published online June 30, 1993
DOI: https://doi.org/10.12701/yujm.1993.10.1.237
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A free-floating ball thrombus in the left atrium is a rare complication of the mitral valvular disease. A 53-year-old man was admitted for pain and paresthesia on both legs. On admission he had auscultatory sign of mitral stenosis and mitral regurgitation, and the roentgenogram of his chest revealed a slight pulmonary ve..ous congestion, enlargement of the pulmonary conus and cardiomegaly. Laboratory findings including complete blood counts, coagulation studies and blood chemistry were normal. An echocardiographic examination revealed a mitral stenosis and a free-floating ball thrombus in the left atrium. We performed the emergent open heart surgery for removal of the ball thrombus and mitral replacement successfuly with Duromedics 29 mm valve. The size of thrombus was 39 X 32 X 30 mm.
Comparision of signal - averaged electrocardiography (SAECG) determined by flank lead system (FLS) and pyramidal lead system (PLS) in healthy young adults.
Byeong Ik Jang, Seung Ho Kang, Hyeung Il Kim, Dong Gu Sin, Young Jo Kim, Bong Sup Shim, Hyun Woo Lee
Yeungnam Univ J Med. 1993;10(1):179-189.   Published online June 30, 1993
DOI: https://doi.org/10.12701/yujm.1993.10.1.179
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It has recently become possible to record electrical activity originationg from abnormally conducting myocardium from the body surface with high-gain amplification and averaging technique. These signals, which result from delayed ventricular activation(late potentials), have been recorded in patients with documented ventricular tachyarrythmia. Several electrode lead system for detecting ventricular late potential were introduced. Pyramidal electrode lead system(PLS) is useful. Also interpretation of SAECG in the young could be of value in detecting those at risk for episodic ventricular tachycardia, but suffer from a lack of data in normal young people. There was no difference between normal values, determined by FLS and PLS at high pass filtering of 25 Hz and 80 Hz, but significant, difference was found in HFLAD and RMS-40 of 40 Hz (p<0.05). These results will provide a basis for interpretations of SAECG, determined by FLS and PLS in healthy young adults with normal QRS duration. SELECTION OF SUBJECTS: For this study, normal healthy young adult volunteers (age : mean 24 years) were recruited from the medical students at Yeungnam University Hospital, Internal Medicine. Twenty fourths male and seventeenths female subjects were selected. All subjects had normal resting ECGs as judged from both the standard 12 channel lead and echocardiography, and none had a history of cardiovascular disease. All subjects were considered to be in good general physical condition. SIGNAL-AVERAGED ELECTROCARDIOGRAPHY: In order to obtain low noise recordings with a small number of averaging cycles, all subject ware asked to relax completely in the supine position. Silver/silver chloride electrodes were attached after the skin was cleaned with alcohol, to constitute classic flank lead system(FLS) and pyramidal lead system(PLS). Signals were recorded and processed using a commercially available microprocessor-augmented ECG cart(Marquette Electronics, USA) suitable for portable bedside recording.
The Role of Free Radicals in Reperfusion Myocardial Injury.
Young Jo Kim, Hyun Woo Lee
Yeungnam Univ J Med. 1991;8(2):1-12.   Published online December 31, 1991
DOI: https://doi.org/10.12701/yujm.1991.8.2.1
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AbstractAbstract PDF
No abstract available.
Ventricular premature complexes and associated factors in the early postinfarction period.
Jong Hoa Choi, Myung Soo Hyun, Young Jo Kim, Bong Sup Shim, Hyun Woo Lee
Yeungnam Univ J Med. 1990;7(1):61-68.   Published online June 30, 1990
DOI: https://doi.org/10.12701/yujm.1990.7.1.61
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To assess the role of multiple factors in influencing occurrence of ventricular premature complexes after acute myocardial infarction twenty-four hour Holter electrocardiographic tape recording were made in 40 survivors of an acute myocardial infarction 10 to 20days after attack. Ventricular premature complexes in the early post infarction period were not correlated with left ventricular function, age, sex, smoking, diabetes mellitus, previous angina, and previous myocardial infarction. The occurrence of ventricular premature complexes showed a positive correlation with the occurrence of ST-T change. The occurrence of ventricular premature complexes during sleep hours was compared to the awake state. In 22 patients, the incidence of ventricular premature complexes are excluded from analysis, the 22 of patients, or in 76 percent, sleep was associated with a lowered occurrence of ventricular extrasystoles.
A Case of Bradycardia-Dependent Complete Atrioventricular(A-V) Block.
Jae Yik Lee, Young Jo Kim, Bong Sup Shim, Hyun Woo Lee
Yeungnam Univ J Med. 1989;6(2):241-245.   Published online December 31, 1989
DOI: https://doi.org/10.12701/yujm.1989.6.2.241
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Induction of A-V block by tachycardia is a well-known phenomenon. But there are few case reports of bradycardia-dependent A-V block. We report a case of bradycardia-dependent A-V block with review of literatures. This patient was a 52-year-old female who complained of dizziness and anterior chest discomfort. Electrocardiographic recording demonstrated complete A-V block. Monitor electrocardiographic recordings during sitting position and after atropine administration demonstrated decrease of degree of block from complete A-V block to first degree A-V block. The occurrence of complete A-V block from bradycardia during supine position suggests a phase 4-dependent block. After a permanent ventricular pacemaker was implanted, the patient recovered and was without symptoms during 12 months follow up.
A Design of High-Frequency Oscillatory Ventilator Using Phase Lock Loop system.
Sang Hag Lee, Dong Gyo Jeong, Joon Ha Lee, Kwan Ho Lee, Young Jo Kim, Jae Chun Chung, Hyun Woo Lee, Suck Kang Lee, Tae Sug Lee
Yeungnam Univ J Med. 1989;6(2):217-222.   Published online December 31, 1989
DOI: https://doi.org/10.12701/yujm.1989.6.2.217
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In this study, high frequency oscillatory ventilator was designed and constructed. Using designed by phase-lock loop system, in order to accurately and easily treat both the outlet volume and rpm. A system has been designed and is being evaluated using CD4046A PLL IC. We use this PLL IC for the purpose of motor controls. The device consists of PLL system, pumping mechanism, piston, cylinder, and special crank shaft are required. This system characteristics were as follows: 1) Frequency: 20-1800 rpm 2) Outlet air volume: 1-50 cc
The Comparison of Histopathology of Cats Received Conventional Mechanical Ventilation and High Frequency Oscillation Ventilation.
Kwan Ho Lee, Young Jo Kim, Jae Chun Chung, Hyun Woo Lee, Hae Joo Nam, Tae Sook Lee
Yeungnam Univ J Med. 1989;6(2):39-46.   Published online December 31, 1989
DOI: https://doi.org/10.12701/yujm.1989.6.2.39
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The tracheobronchial histopathologic findings in 7 healthy cats used with high frequency oscillation ventilation (HFOV) were compared with those in 6 cats used with conventional mechanical ventilation (CMV). 4-point, 9-variable scoring system was used to evaluate the injury in the trachea, right & left main bronchi and parenchyma. The following results were obtained; 1) The tracheobronchial tree received HFOV had no significant damage compared with CMV (P>0.05). 2) Intraepithelial mucus loss and emphysema were slightly more prominent in CMV groups. As above results; the tracheobronchial histopathologic difference was not prominent between CMV and HFOV groups received with relatively short period, however, the cellular of function and barotrauma may be more prominent in CMV groups. From now on, as causes of tracheobronchial injury in HFV, interaction between humidification and mechanical trauma considers further study.
A Case of Dissection in Marfan Syndrome with Ascending Aortic Aneurysm.
Bong Young Yoon, Chang Heon Yang, Young Jo Kim, Bong Sup Shim, Hyun Woo Lee, Han Young Ryu, Tae Eun Jung, Yee Tae Park, Sung Sae Han
Yeungnam Univ J Med. 1989;6(1):179-184.   Published online June 30, 1989
DOI: https://doi.org/10.12701/yujm.1989.6.1.179
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The Marfan syndrome is a generalized connective tissue disease involving eye, musculoskeletal system, cardiovascular system, and inherited autosomal dominant with various expression type. The cardiovascular complications such as aortic aneurysm, aortic dissection, aortic regurgitation, mitral regurgitation and aortic dissection which usually occurs in previously normal sized aorta are poor prognostic factors. However, the aortic dissection which developed in patient with Marfan syndrome and aortic aneurysm was rare. We experienced one case of dissecting aneurysm in patient diagnosed as previous aortic aneurysm, aortic regurgitation, and Marfan syndrome, receiving successful operation.
The Clinical Value of the 24-hour Ambulatory ECG Monitoring in Patients with Chronic Atrial Fibrillation.
Chang Heon Yang, Young Jo Kim, Bong Sup Shim, Hyun Woo Lee
Yeungnam Univ J Med. 1989;6(1):99-107.   Published online June 30, 1989
DOI: https://doi.org/10.12701/yujm.1989.6.1.99
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24-hour ambulatory ECG monitoring has been examined for the evaluation of heart rate and longest pause in 34 patients with chronic atrial fibrillation (20 patients treated with digoxin and 14 patients without treatment). Following results were obtained: 1. In 34 patients, the mean of average heart rates was 75.7±13.8/minute, fastest heart rates 148.0±32.4/minute, slowest heart rates 48.1±8.4/minute, difference between fastest and slowest heart rates in individual patients 99.9±29.0/minute and longest pauses 2.95±1.06seconds. The longest pauses of more than 4.0 seconds occurred in 4 of the 34 patients and made an exception of comparison groups. 2. In 27 of the 34 patients, ventricular premature contractures were developed and in 11 of 27, mainly occurred less than 100/24 hours and aberrant conduction occurred in all patients. 3. In 20 patients treated with digoxin (0.25 mg/day), the mean of average heart rates was 78.4±13.7/minute, fastest heart rates 152.5±33.1/minute, slowest heart rates 48.9±8.5/minute, difference between fastest and slowest heart rates in individual patients 103.6±31.7/minute and longest pauses 2.55±0.50 seconds. 4. In 10 patients without treatment, the mean of average heart rates was 78.0±10.7/minute, fastest heart rates 154.5±26.8/minute, slowest heart rates 50.6±7.1/minute, difference between fastest and slowest heart rates in individual patients 103.9±22.2/minute and longest pauses 2.66±0.39 seconds. 5. The difference of heart rates and longest pauses between patients with treatment and without treatment were statistically not significant (P>0.05). In summary, authors seemed to consider that 24-hour ambulatory ECG was useful and safe method for clinical evaluation of patients with chronic atrial fibrillation.
Extra-LDH Isoenzyme(LD₆) in Myocardial Infarction with Serious Course: Two cases report.
Kyung Dong Kim, Myung Sook Choi, Chae Hoon Lee, Chang Ho Jeon, Chung Sook Kim, Young Jo Kim
Yeungnam Univ J Med. 1988;5(2):247-254.   Published online December 31, 1988
DOI: https://doi.org/10.12701/yujm.1988.5.2.247
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Serum lactate dehydrogenase isoenzyme are separated 5 fractions (LD1-LD5) in normal serum by agarose electrophoresis. An unusual band on the cathodic side of LD5 isoenzyme has been found on lactate dehydrogenase electrophoresis is of serum, called LD6, and the presence of which signifies a poor prognosis for the patients of myocardial infarction. In recent, we have experienced LD6 in two patients with myocardial infarction. Cardiac arrest was noted within 24 hours after exhibition of LD6 extra band and they did not recover from their illness.
Chronic Dissecting Aortic Aneurysm with Right Coronary Artery Perfused Solely by False Lumen of Asceading Aorta.
Myeong Gu Go, Jong Myung Kim, Kwan Ho Lee, Young Jo Kim, Bong Sup Shim, Hyun Woo Lee, Mi Soo Hwang
Yeungnam Univ J Med. 1988;5(1):159-166.   Published online June 30, 1988
DOI: https://doi.org/10.12701/yujm.1988.5.1.159
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Dissecting aortic aneurysm is relatively rare in those under 40 years of age without high risk factors. After dissecting aortic aneurysm is occurred, the coronary artery is rarely perfused by false lumen. We present a thirty two-year-old man who showed Debakey type 1 dissecting aortic aneurysm with right coronary artery perfused by false lumen of ascending aorta and with congestive heart failure due to aortic insufficiency without discernible risk factor. Medical and surgical treatment (Modified Bentall's operation) were successfully performed. The pathologic report showed combined cystic medial necrosis. Now he is well tolerated and stable only with anticoagulation during follow up 18 months.
Histiocytic Medullary Reticulosis.
Kyoung Hee Lee, Myung Soo Hyun, Young Jo Kim, Bong Sup Shim, Kyung Dong Kim, Chung Sook Kim, Won Hee Choi, Tae Sook Lee
Yeungnam Univ J Med. 1987;4(2):165-172.   Published online December 31, 1987
DOI: https://doi.org/10.12701/yujm.1987.4.2.165
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The term histiocytic medullary reticulosis first was introduced by Scott and Robb-Smith. It is a clinicopathologic syndrome characterized by wasting, fever, lymphadenopathy, hepatosplenomegaly, pancytopenia, and is often accompanied by jaundice, purpura. Cardinal pathologic feature are systemized proliferation of atypical, neoplastic, erythrophagocytic D. We are here reporting one case which considered compatible for HMR, with a few elementary reviewed literatures.
A Case Report of Primary Pericardial Malignant Epitheloid Mesothelioma.
Moon Ho Chung, Myung Soo Hyun, Young Jo Kim, Bong Sup Shim, Chong Suhi Kim, Dong Hyup Lee, Cheol Joo Lee, Myeun Shik Kang
Yeungnam Univ J Med. 1986;3(1):301-306.   Published online December 31, 1986
DOI: https://doi.org/10.12701/yujm.1986.3.1.301
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Primary pericardial mesothelioma is a rare tumor of mesodermal origin that is infrequently diagnosed antemortem and survival is short. A 60 year old male case of pericardial mesothelioma (epitheloid type) is reported. He was admitted to Yeungnam University Hospital because of chest pain, dyspnea, orthopnea and nonproductive cough. Chest x-ray suggested pericardial effusion. 2-D echocardiography showed echo free spaces of massive pericardial effusion and areas of thick hyperrefractile echoes arising from the pericardium. Pericardiocentesis was attempted and aspirated fluid was bloody exudates. Pericardial window operation with biopsy was done. Swan-Ganz catheterization showed equalization between right atrial pressure and pulmonary capillary wedge pressure. The pathologic diagnosis was established by histologic finding at pericardial biopsy.
A Case Report of Ventricular Septal Defect with Bacterial Endocarditis and Pulmonic Valve Vegetation.
Wha Chong Park, Young Jo Kim, Bong Sup Sim, Chong Suhl Kim, Dong Hyup Lee, Cheol Joo Lee, Bum Koo Cho
Yeungnam Univ J Med. 1985;2(1):241-247.   Published online December 31, 1985
DOI: https://doi.org/10.12701/yujm.1985.2.1.241
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Bacterial endocarditis has been well recognized as an important complication of congenital heart disease, such as ventricular septal defect, patent ductus arteriosus or pulmonary stenosis. The incidence of right sided bacterial endocarditis is lesser than left sided bacterial endocarditis. Also, pulmonic valve vegetation has been thought to be relatively uncommon. So in a patient with fever and evidence of recurrent pulmonary infarction, changing heart murmurs and scattered pneumonic infiltrates, one should direct attention to the heart as a possible source of the infection. Echocardiography with M-mode, 2-D and Doppler mode represents the only noninvasive technic available for detecting vegetations in bacterial endocarditis. In fact, the technic is more sensitive in identifying these lesions than angiography. We experienced a case of ventricular septal defect with bacterial endocarditis, pulmonic valve vegetation and multiple pulmonary embolism diagnosed with Echocardiogram and lung scan, and confirmed by operation. Patch repair of ventricular septal defect, resection of pulmonic valve and vegetation and artificial valve formation with pericardium were done.

JYMS : Journal of Yeungnam Medical Science