- Multidisciplinary approach to sarcopenia: a narrative review
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Wook Tae Park, Oog-Jin Shon, Gi Beom Kim
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J Yeungnam Med Sci. 2023;40(4):352-363. Published online September 7, 2023
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DOI: https://doi.org/10.12701/jyms.2023.00724
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Abstract
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- Sarcopenia is a condition in which muscle mass and strength are decreased and muscle function is impaired. It is an indicator of frailty and loss of independence in older adults. It is also associated with increased physical disability, which increases the risk of falls. As a multifactorial disease, sarcopenia is caused by a combination of factors including aging, hormonal changes, nutritional deficiencies, and physical inactivity. Understanding the underlying pathophysiology of sarcopenia and identifying its different causes is critical to developing effective prevention and treatment strategies. This review summarizes the pathophysiology, consequences, diagnostic methods, and multidisciplinary approaches to sarcopenia.
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- Head and Neck Cancer and Sarcopenia: An Integrative Clinical and Functional Review
Kazuhira Endo, Mariko Ichinose, Eiji Kobayashi, Takayoshi Ueno, Nobuyuki Hirai, Yosuke Nakanishi, Satoru Kondo, Tomokazu Yoshizaki Cancers.2024; 16(20): 3460. CrossRef - Economic burden of sarcopenia-related disability in the elderly population: a study in Iran
Ali Darvishi, Adeleh Nikkhah, Gita Shafiee, Rajabali Daroudi, Ramin Heshmat BMC Research Notes.2024;[Epub] CrossRef
- Current perspectives in stem cell therapies for osteoarthritis of the knee
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Gi Beom Kim, Oog-Jin Shon
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Yeungnam Univ J Med. 2020;37(3):149-158. Published online April 13, 2020
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DOI: https://doi.org/10.12701/yujm.2020.00157
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- Mesenchymal stem cells (MSCs) are emerging as an attractive option for osteoarthritis (OA) of the knee joint, due to their marked disease-modifying ability and chondrogenic potential. MSCs can be isolated from various organ tissues, such as bone marrow, adipose tissue, synovium, umbilical cord blood, and articular cartilage with similar phenotypic characteristics but different proliferation and differentiation potentials. They can be differentiated into a variety of connective tissues such as bone, adipose tissue, cartilage, intervertebral discs, ligaments, and muscles. Although several studies have reported on the clinical efficacy of MSCs in knee OA, the results lack consistency. Furthermore, there is no consensus regarding the proper cell dosage and application method to achieve the optimal effect of stem cells. Therefore, the purpose of this study is to review the characteristics of various type of stem cells in knee OA, especially MSCs. Moreover, we summarize the clinical issues faced during the application of MSCs.
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- Clinical Evaluation of Safety and Efficacy of a Central Current Good Manufacturing Practices Laboratory Produced Autologous Adipose-Derived Stromal Vascular Fraction Cell Therapy Product for the Treatment of Knee Osteoarthritis
Christopher J. Rogers, Robert Harman, Mitchell B. Sheinkop, Peter Hanson, Mary A. Ambach, Tal David, Rahul Desai, Steven Sampson, Danielle Aufierro, Jay Bowen, Gerard Malanga Stem Cells and Development.2024; 33(7-8): 168. CrossRef - Safety and efficacy of an allogeneic adipose-derived mesenchymal stem cell preparation in the treatment of knee osteoarthritis: A Phase I/IIa randomised controlled trial
Julien Freitag, Matthew Chamberlain, James Wickham, Kiran Shah, Flavia Cicuttini, Yuanyuan Wang, Ann Solterbeck, Lucinda Kenihan, Lesley-Anne Kelly, Renee Castelluccio, Ellee Picken, Melissa Grogan, Michael Kenihan, Abi Tenen, Nirali Shah, Carla Lutz, Tee Osteoarthritis and Cartilage Open.2024; 6(3): 100500. CrossRef - Human umbilical cord mesenchymal stem cells promoting knee joint chondrogenesis for the treatment of knee osteoarthritis: a systematic review
Pengwei Zhang, Bo Dong, Puwei Yuan, Xun Li Journal of Orthopaedic Surgery and Research.2023;[Epub] CrossRef - Scaffold-Free Cartilage Construct from Infrapatellar Fat Pad Stem Cells for Cartilage Restoration
Orada Sriwatananukulkit, Tulyapruek Tawonsawatruk, Kasem Rattanapinyopituk, Ticomporn Luangwattanawilai, Narongrit Srikaew, Ruedee Hemstapat Tissue Engineering Part A.2022; 28(5-6): 199. CrossRef - Autologous Protein Solution Effect on Chondrogenic Differentiation of Mesenchymal Stem Cells from Adipose Tissue and Bone Marrow in an Osteoarthritic Environment
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Gi Beom Kim, Oog-Jin Shon, Min-Soo Seo, Young Choi, Wook Tae Park, Gun Woo Lee Biology.2021; 10(4): 285. CrossRef - Molecular basis for new approaches to therapy of osteoarthritis (part I)
E. V. Chetina, G. A. Markova, A. M. Lila Modern Rheumatology Journal.2021; 15(4): 7. CrossRef - The therapeutic potential of mesenchymal stem cells in treating osteoporosis
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