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JYMS : Journal of Yeungnam Medical Science

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Keyong Hee Lee 1 Article
Gastric mucosal damage by bile acid.
Hyun Hong Cho, Jeong Ill Suh, Keyong Hee Lee, Tae Nyeun Kim, Moon Kwan Chung, Hyun Woo Lee, Won Hee Choi, Chang Heon Yang
Yeungnam Univ J Med. 1992;9(2):342-350.   Published online December 31, 1992
DOI: https://doi.org/10.12701/yujm.1992.9.2.342
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To investigate the effect of bile acid on gastric mucosa, we performed biologic test using Sprague-Dawley rat. Mixture solution of TDCA 15mM and Hcl of pH 3 was given into stomach to one group and HCl of pH 3 was given into stomach to another group. The significant gastric mucosal change was vasodilation and edema, that was disappeared progressively. These findings suggest the bile acid and damage gastric mucosa.

JYMS : Journal of Yeungnam Medical Science