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JYMS : Journal of Yeungnam Medical Science

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Jun hyuk Son 2 Articles
Ocular adnexal mucosa-associated lymphoid tissue lymphoma: a narrative review
Hyun Uk Chung, Jun Hyuk Son
J Yeungnam Med Sci. 2022;39(1):3-11.   Published online September 15, 2021
  • 5,539 View
  • 159 Download
  • 8 Web of Science
  • 6 Crossref
AbstractAbstract PDF
Lymphoma is the most common primary tumor of the orbit, accounting for 55% of all orbital malignancies. When divided into histopathological subtypes, extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) comprises the largest proportion. Clinical manifestations are unspecific, but in patients with slow-growing painless orbital mass, or red conjunctival lesion suggestive of ‘salmon patch’, ocular adnexa lymphoma (OAL) should be suspected. Although the pathogenetic mechanism of ocular adnexal MALT lymphoma (OAML) is not yet fully understood, the relationship between OAML and Chlamydia psittaci has been hypothesized recently, similar to that between gastric MALT lymphoma and Helicobacter pylori. This suggests a new treatment option for OAML; bacterial eradication therapy with systemic antibiotics. Several other treatment methods for OAML have been introduced, but no treatment guidelines have been established yet. In this article, we summarize the current knowledge on the clinical features, pathogenesis, diagnostic methods, therapeutic strategies, and prognosis of OAML.


Citations to this article as recorded by  
  • Unusual Pediatric Red Eye
    Carson W. Ercanbrack, Jamal O. Azhari, David B. Warner, Maher Abulfaraj, Abdelrahman M. Elhusseiny
    The Journal of Pediatrics.2024; 267: 113924.     CrossRef
  • The Possible Role of Pathogens and Chronic Immune Stimulation in the Development of Diffuse Large B-Cell Lymphoma
    Lajos Gergely, Miklos Udvardy, Arpad Illes
    Biomedicines.2024; 12(3): 648.     CrossRef
  • Radiomics analysis of T1WI and T2WI magnetic resonance images to differentiate between IgG4-related ophthalmic disease and orbital MALT lymphoma
    Yuchao Shao, Yuqing Chen, Sainan Chen, Ruili Wei
    BMC Ophthalmology.2023;[Epub]     CrossRef
  • Etiopathogenesis of primary acquired nasolacrimal duct obstruction (PANDO)
    Mohammad Javed Ali
    Progress in Retinal and Eye Research.2023; 96: 101193.     CrossRef
  • The Biology of Ocular Adnexal Marginal Zone Lymphomas
    Patricia Johansson, Anja Eckstein, Ralf Küppers
    Cancers.2022; 14(5): 1264.     CrossRef
  • One Case of Conjunctival MALT Lymphoma and Literature Review
    旭霞 李
    Advances in Clinical Medicine.2022; 12(08): 7586.     CrossRef
Trabeculectomy Using Mitomycin C in Aphakic and Pseudophakic Eyes.
Jun hyuk Son, Soon Cheol Cha
Yeungnam Univ J Med. 2007;24(2):232-242.   Published online December 31, 2007
  • 1,604 View
  • 1 Download
AbstractAbstract PDF
The safety and efficacy of trabeculectomy with Mitomycin C (MMC) for surgical treatment in aphakic and pseudophaic eyes were retrospectively evaluated. MATERIALS AND METHODS: The authors reviewed 51 eyes of 45 patients who had been followed up for at least 6 months after trabeculectomy using MMC for aphakic and pseudophakic eyes. The success rate and complications were analyzed. The success criteria included intraocular pressures of 21 mmHg or less with or without glaucoma medications and no loss of light perception. Surgical failure was defined as a postoperative loss of light perception in patients with preoperative vision better than light perception, additional glaucoma surgery, or phthisis bulbi in patients with preoperative vision of no light perception. RESULTS: The average follow up period was 27.7 months and the intraocular pressure was controlled under 21 mmHg in 36 eyes of 51 (70.6%) after the procedure with or without medication for glaucoma. Using the Kaplan-Meier survival analysis, the cumulative success rate at the 3-, 6-, 12-, 24- and 36-month intervals were 98.0%, 94.1%, 91.9%, 83.4% and 75.5%, respectively. The complications observed were hyphema (4 eyes), serous choroidal detachment (4 eyes), hypotony (3 eyes), and endophthalmitis (1 eye). CONCLUSION: Trabeculectomy using Mitomycin C for the treatment of aphakic and pseudophaic eyes was safe and effective.

JYMS : Journal of Yeungnam Medical Science