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JYMS : Journal of Yeungnam Medical Science

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Dong Hwan Ryu 2 Articles
A Case of Pyoderma Gangrenosum in Rheumotoid Arthritis Patient.
Dong Hwan Ryu, Chang Mo Kwon, Jung Hun Lee, Young Hun Hong, Choong Ki Lee
Yeungnam Univ J Med. 2003;20(1):79-84.   Published online June 30, 2003
DOI: https://doi.org/10.12701/yujm.2003.20.1.79
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AbstractAbstract PDF
Pyoderma gangrenosum is uncommon neutrophilic dermatosis characterized by richness of the mature neutrophilic polynuclear dermal infiltrate. Pyoderma gangrenosum is associated with variable diseases, most commonly inflammatory bowel disease, hematological diseases, malignancies, but it is reported rarely in rheumatoid arthritis. We report a case of pyoderma gangrenosum in rheumoid arthritis patient. A 50-year-old woman admitted to our hospital due to painful pretibial ulcerative skin lesions. She had been treated as rheumatoid arthritis for 8 years. At admission, body temperature was 36.5degrees C and other vital sign was unremarkable. Physical examination revealed right pretibial ulceration, multiple pustules on left pretibial area and both palms. Laboratory studies revealed WBC count 7,600/uL (neutrophils 60.3%, eosinophil 3.2%), hemoglobin 11.4 g/dL, platelet count 319,000/uL, ESR 65 mm/hour. Other lab findings were also unremarkable. Skin biopsy was done, which showed dense dermal infiltrate of neutrophils and wound culture were negative. By 8 weeks after systemic high dose corticosteroid (1 mg/kg/day), cyclosporine A (5 mg/kg/day), sulfasalazine 2 g therapy, symptoms and skin ulceration were being improved. Without skin relapse, she is followed up our hospital with low dose corticosteroid and sulfasalazine.
Symptomatic Sacroiliitis in Female Systemic Lupus Erythematosus.
Ki Do Park, Young Hun Hong, Sung Dong Kim, Dong Hwan Ryu, Coong Ki Lee
Yeungnam Univ J Med. 2000;17(2):161-164.   Published online December 31, 2000
DOI: https://doi.org/10.12701/yujm.2000.17.2.161
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AbstractAbstract PDF
We report a case of 17-year-old female with juvenile onset systemic lupus erythematosus Who developed symptomatic unilateral sacroiliitis. She had neither HLA-DR3 nir B27 antigens. Though sacroiliitis have been reported in mail SLE patient. it has been rarely reported in female patients. The rare coexistence of SLE and sacroiliitis. described in this case. may not be determined soley by genetic factors; sacroiliitis may be just an infrequent manifestation of SLE.

JYMS : Journal of Yeungnam Medical Science