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JYMS : Journal of Yeungnam Medical Science

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Bo Young Lee 2 Articles
A Case of Neurotoxicity Induced by Valaciclovir in a Continuous Ambulatory Peritoneal Dialysis Patient.
Joon Seok Kim, Jee Eun Yang, Bo Young Lee, Seohyun Lee, Hee Jung Park, Sunpyo Lee, Sang Koo Lee
Yeungnam Univ J Med. 2012;29(2):121-124.   Published online December 31, 2012
DOI: https://doi.org/10.12701/yujm.2012.29.2.121
  • 1,900 View
  • 6 Download
  • 2 Crossref
AbstractAbstract PDF
Valaciclovir is metabolized to acyclovir after ingestion and thereafter exerts its antiviral activity. Because of its superior pharmacokinetic profile, it has quickly replaced acyclovir in the treatment of herpesvirus infection. Neurotoxicity caused by valaciclovir has been reported, however, among patients with pre-existing impaired renal function. This paper reports a case of neurotoxicity of valaciclovir in a patient with end-stage renal disease who was undergoing continuous ambulatory peritoneal dialysis (CAPD). A 67-year-old female on CAPD took 500 mg of valaciclovir twice for herpes zoster. After she took her second dose orally, she developed confusion and disorientation, along with involuntary movements. Her mental confusion progressed to a coma. Discontinuation of valaciclovir showed no rapid improvement. There- fore, hemodialysis was started. After two sessions of hemodialysis, the patient became alert; and after four sessions of hemodialysis, her neurological abnormalities were completely reversed. In conclusion, valaciclovir can induce life-threatening neurotoxicity, especially in CAPD patients, even with appropriate dose reduction, which can be effectively managed by hemodialysis.

Citations

Citations to this article as recorded by  
  • Comparison of Renal Function Indicators According to Hydration Volume in Patients Receiving Intravenous Acyclovir With CNS Infection
    Sanghee Kim, Youngsoon Byun
    Biological Research For Nursing.2015; 17(1): 55.     CrossRef
  • Valacyclovir-Induced Neurotoxicity in a Maintenance Hemodialysis Patient
    June Seong Hwang, Hyo Yoep Song, Hoon Gil Jo, Song I Lee, Byung Hun Lim, Jung Sub Song, Seon Ho Ahn
    Journal of the Korean Geriatrics Society.2014; 18(2): 85.     CrossRef
A Case of Ruptured Mycotic Hepatic Artery Aneurysm Successfully Treated Using Arterial Embolization.
Gi Ae Kim, Han Chu Lee, Young Joo Jin, Jee Eun Yang, Min Jung Lee, Ji Hyun Park, Bo Young Lee
Yeungnam Univ J Med. 2012;29(1):24-27.   Published online June 30, 2012
DOI: https://doi.org/10.12701/yujm.2012.29.1.24
  • 1,932 View
  • 2 Download
  • 3 Crossref
AbstractAbstract PDF
Mycotic hepatic artery aneurysms (HAAs) have become very rare due to antibiotics. Untreated, they have a high possibility of rupture and mortality. In this paper, on the case of a 67-year-old male who had severe right-upperquadrant abdominal pain and a history of infective endocarditis is reported. The computed tomography (CT) and arterial angiography findings led to a diagnosis of a ruptured mycotic HAA. The CT showed an HAA and the formation of an intrahepatic hematoma caused by aneurysmal rupture. The arterial angiography showed a mycotic HAA that arose from the right posterior hepatic artery. Percutaneous transcatheter arterial embolization was used to successfully treat the HAA. Since then, the patient has been doing well, without symptoms.

Citations

Citations to this article as recorded by  
  • Hepatic Artery Aneurysms in Infective Endocarditis: Report of 10 Cases and Literature Review
    Monique Boukobza, Emila Ilic-Habensus, Florent Arregle, Gilbert Habib, Xavier Duval, Jean-Pierre Laissy
    Annals of Vascular Surgery.2024; 105: 252.     CrossRef
  • A mycotic hepatic artery aneurysm, a rare complication of aortic valve endocarditis.
    Jaime López-Sánchez , José Quiñones Sampedro , Luis Muñoz-Bellvís
    Revista Española de Enfermedades Digestivas.2020;[Epub]     CrossRef
  • Hepatic Artery Mycotic Aneurysm Associated with Staphylococcal Endocarditis with Successful Treatment: Case Report with Review of the Literature
    Dhara Chaudhari, Atif Saleem, Pranav Patel, Sara Khan, Mark Young, Gene LeSage
    Case Reports in Hepatology.2013; 2013: 1.     CrossRef

JYMS : Journal of Yeungnam Medical Science