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JYMS : Journal of Yeungnam Medical Science

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1 "Glial fibrillary acidic protein"
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Case report
Extramedullary tanycytic ependymoma of the lumbar spinal cord
Dong Ja Kim, Man-Hoon Han, SangHan Lee
Yeungnam Univ J Med. 2020;37(2):128-132.   Published online November 11, 2019
DOI: https://doi.org/10.12701/yujm.2019.00367
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AbstractAbstract PDF
Tanycytic ependymoma is a rare variant of ependymoma that commonly affects the cervical and thoracic spinal cord. It usually arises as intramedullary lesions, and extramedullary cases are extremely rare. We report a case of a 44-year-old woman who was diagnosed with tanycytic ependymoma in her lumbar spine at level 2-3. The tumor mass developed in an intradural extramedullary location. Histopathologically, tanycytic ependymoma can be misdiagnosed as schwannoma or pilocytic astrocytoma. Immunohistochemical findings such as strong positivity for glial fibrillary acidic protein, perinuclear dot-like positive patterns for epithelial membrane antigen, and focal positivity for S-100 are helpful in diagnosing tanycytic ependymoma. It is important to be aware of this rare tumor to ensure appropriate patient management and accurate prognosis.

Citations

Citations to this article as recorded by  
  • Whorling Sclerosing Ependymoma of the Cervical Spinal Cord Presenting Tanycytic Histopathologic Features: A Rare Case Report
    Cumhur Kaan Yaltırık, Emin Oğuzcan Yamaner, Öznur Suakar, Sezin Gürkan, Aydın Sav, Uğur Türe
    International Journal of Surgical Pathology.2023; 31(2): 239.     CrossRef
  • Stretched intradural extramedullary tanycytic ependymoma of the thoracic spine
    Nicola Montemurro, Daniele Lorenzini, Valerio Ortenzi, Jacopo Giorgetti
    Surgical Neurology International.2022; 13: 426.     CrossRef
  • Intradural extramedullary tanycytic ependymoma of the cervical spine: A case report
    Mahmoud M. Taha, Mazen M. Taha, Mohamed Kh. Elbadawy, Mohammad Ezzat
    Interdisciplinary Neurosurgery.2021; 26: 101319.     CrossRef

JYMS : Journal of Yeungnam Medical Science